Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QF07_LEIMA

TriTrypDb:

LmjF.16.0130 , LMJLV39_160006400 , LMJSD75_160006400

Length:

208

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QF07

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QF07

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	35	37	PF00675	0.426
CLV_NRD_NRD_1	68	70	PF00675	0.554
CLV_PCSK_KEX2_1	35	37	PF00082	0.433
CLV_PCSK_KEX2_1	63	65	PF00082	0.513
CLV_PCSK_KEX2_1	68	70	PF00082	0.488
CLV_PCSK_PC1ET2_1	63	65	PF00082	0.498
CLV_PCSK_PC7_1	64	70	PF00082	0.514
CLV_PCSK_SKI1_1	122	126	PF00082	0.434
CLV_PCSK_SKI1_1	26	30	PF00082	0.565
CLV_PCSK_SKI1_1	68	72	PF00082	0.454
DEG_APCC_DBOX_1	114	122	PF00400	0.483
DEG_APCC_DBOX_1	68	76	PF00400	0.567
DEG_SPOP_SBC_1	163	167	PF00917	0.533
DOC_CYCLIN_RxL_1	117	130	PF00134	0.486
DOC_CYCLIN_RxL_1	63	73	PF00134	0.447
DOC_MAPK_gen_1	117	126	PF00069	0.481
DOC_MAPK_MEF2A_6	120	128	PF00069	0.490
DOC_PP1_RVXF_1	24	30	PF00149	0.412
DOC_USP7_MATH_1	144	148	PF00917	0.532
DOC_USP7_MATH_1	163	167	PF00917	0.550
DOC_USP7_MATH_1	44	48	PF00917	0.535
DOC_USP7_MATH_1	91	95	PF00917	0.567
DOC_USP7_UBL2_3	39	43	PF12436	0.522
DOC_WW_Pin1_4	140	145	PF00397	0.592
DOC_WW_Pin1_4	75	80	PF00397	0.551
LIG_14-3-3_CanoR_1	64	72	PF00244	0.445
LIG_deltaCOP1_diTrp_1	182	191	PF00928	0.506
LIG_FHA_1	165	171	PF00498	0.745
LIG_FHA_1	48	54	PF00498	0.530
LIG_FHA_1	76	82	PF00498	0.587
LIG_FHA_1	94	100	PF00498	0.490
LIG_FHA_2	2	8	PF00498	0.583
LIG_MYND_1	140	144	PF01753	0.589
LIG_SH2_NCK_1	30	34	PF00017	0.476
LIG_SH2_SRC	30	33	PF00017	0.612
LIG_SH2_STAT3	10	13	PF00017	0.493
LIG_SH3_3	76	82	PF00018	0.548
LIG_TRAF2_1	132	135	PF00917	0.566
MOD_CDK_SPK_2	75	80	PF00069	0.484
MOD_CK1_1	143	149	PF00069	0.607
MOD_CK1_1	165	171	PF00069	0.534
MOD_CK1_1	47	53	PF00069	0.530
MOD_CK1_1	94	100	PF00069	0.479
MOD_CK2_1	128	134	PF00069	0.498
MOD_GlcNHglycan	130	133	PF01048	0.533
MOD_GlcNHglycan	155	159	PF01048	0.705
MOD_GlcNHglycan	96	99	PF01048	0.531
MOD_GSK3_1	140	147	PF00069	0.522
MOD_GSK3_1	161	168	PF00069	0.675
MOD_GSK3_1	174	181	PF00069	0.464
MOD_NEK2_1	1	6	PF00069	0.586
MOD_NEK2_1	198	203	PF00069	0.490
MOD_PK_1	80	86	PF00069	0.590
MOD_PKA_1	63	69	PF00069	0.514
MOD_PKA_2	174	180	PF00069	0.589
MOD_PKA_2	63	69	PF00069	0.514
MOD_Plk_1	134	140	PF00069	0.540
MOD_Plk_1	6	12	PF00069	0.480
MOD_Plk_4	165	171	PF00069	0.643
MOD_Plk_4	198	204	PF00069	0.496
MOD_ProDKin_1	140	146	PF00069	0.593
MOD_ProDKin_1	75	81	PF00069	0.555
TRG_ENDOCYTIC_2	30	33	PF00928	0.442
TRG_ER_diArg_1	115	118	PF00400	0.485
TRG_ER_diArg_1	138	141	PF00400	0.474
TRG_NES_CRM1_1	116	130	PF08389	0.382
TRG_Pf-PMV_PEXEL_1	122	127	PF00026	0.588
TRG_Pf-PMV_PEXEL_1	69	73	PF00026	0.455

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0H3	Leptomonas seymouri	32%	100%
A0A3Q8IIW8	Leishmania donovani	80%	100%
A4HWR2	Leishmania infantum	81%	100%
E9AQG9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	100%