OAR domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QF05_LEIMA

TriTrypDb:

LmjF.16.0150 , LMJLV39_160006600 , LMJSD75_160006600

Length:

234

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QF05

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QF05

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	125	127	PF00675	0.714
CLV_PCSK_KEX2_1	125	127	PF00082	0.643
CLV_PCSK_KEX2_1	218	220	PF00082	0.439
CLV_PCSK_PC1ET2_1	218	220	PF00082	0.454
CLV_PCSK_SKI1_1	24	28	PF00082	0.546
DEG_SCF_FBW7_1	108	115	PF00400	0.597
DOC_CYCLIN_yCln2_LP_2	164	170	PF00134	0.615
DOC_PP2B_LxvP_1	164	167	PF13499	0.609
DOC_USP7_MATH_1	114	118	PF00917	0.600
DOC_USP7_MATH_1	156	160	PF00917	0.560
DOC_USP7_MATH_1	16	20	PF00917	0.548
DOC_USP7_MATH_1	178	182	PF00917	0.598
DOC_USP7_MATH_1	228	232	PF00917	0.497
DOC_WW_Pin1_4	106	111	PF00397	0.619
DOC_WW_Pin1_4	112	117	PF00397	0.669
DOC_WW_Pin1_4	126	131	PF00397	0.503
DOC_WW_Pin1_4	170	175	PF00397	0.606
DOC_WW_Pin1_4	195	200	PF00397	0.619
DOC_WW_Pin1_4	94	99	PF00397	0.530
LIG_14-3-3_CanoR_1	4	10	PF00244	0.507
LIG_BRCT_BRCA1_1	18	22	PF00533	0.473
LIG_FHA_1	205	211	PF00498	0.499
LIG_FHA_1	221	227	PF00498	0.480
LIG_FHA_1	73	79	PF00498	0.483
LIG_Integrin_isoDGR_2	185	187	PF01839	0.645
LIG_LIR_Gen_1	73	82	PF02991	0.573
LIG_LIR_Nem_3	51	57	PF02991	0.518
LIG_LIR_Nem_3	73	77	PF02991	0.548
LIG_NRBOX	22	28	PF00104	0.546
LIG_Pex14_2	208	212	PF04695	0.576
LIG_SH2_CRK	74	78	PF00017	0.609
LIG_SH2_STAP1	74	78	PF00017	0.609
LIG_SH2_STAT5	74	77	PF00017	0.568
LIG_SH3_3	113	119	PF00018	0.601
LIG_SH3_3	196	202	PF00018	0.615
LIG_SH3_3	59	65	PF00018	0.633
LIG_SH3_CIN85_PxpxPR_1	65	70	PF14604	0.507
LIG_TRAF2_1	119	122	PF00917	0.564
MOD_CDC14_SPxK_1	115	118	PF00782	0.568
MOD_CDK_SPxK_1	112	118	PF00069	0.568
MOD_CK1_1	204	210	PF00069	0.485
MOD_DYRK1A_RPxSP_1	126	130	PF00069	0.588
MOD_GlcNHglycan	181	184	PF01048	0.623
MOD_GlcNHglycan	203	206	PF01048	0.531
MOD_GSK3_1	108	115	PF00069	0.593
MOD_GSK3_1	5	12	PF00069	0.516
MOD_PIKK_1	156	162	PF00454	0.578
MOD_PKA_2	156	162	PF00069	0.557
MOD_PKB_1	70	78	PF00069	0.515
MOD_Plk_1	72	78	PF00069	0.584
MOD_ProDKin_1	106	112	PF00069	0.617
MOD_ProDKin_1	126	132	PF00069	0.590
MOD_ProDKin_1	170	176	PF00069	0.607
MOD_ProDKin_1	195	201	PF00069	0.615
MOD_ProDKin_1	94	100	PF00069	0.535
MOD_SUMO_for_1	33	36	PF00179	0.489
MOD_SUMO_rev_2	213	220	PF00179	0.474
TRG_ENDOCYTIC_2	74	77	PF00928	0.605
TRG_ER_diArg_1	124	126	PF00400	0.647
TRG_ER_diArg_1	69	72	PF00400	0.503
TRG_Pf-PMV_PEXEL_1	55	59	PF00026	0.541

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFT2	Leptomonas seymouri	44%	100%
A0A3S7WTR0	Leishmania donovani	88%	100%
A4H8E2	Leishmania braziliensis	61%	67%
A4HWR4	Leishmania infantum	88%	100%
E9AQH2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%