XRN_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

XRN 5'-3' exonuclease N-terminus, putative

Species:

Leishmania major

UniProt:

Q4QEY1_LEIMA

TriTrypDb:

LmjF.16.0390 , LMJLV39_160009200 , LMJSD75_160009200

Length:

985

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0005730	nucleolus	5	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4QEY1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QEY1

Function

Biological processes
Term	Name	Level	Count
GO:0000956	nuclear-transcribed mRNA catabolic process	7	2
GO:0006139	nucleobase-containing compound metabolic process	3	2
GO:0006401	RNA catabolic process	5	2
GO:0006402	mRNA catabolic process	6	2
GO:0006725	cellular aromatic compound metabolic process	3	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0008152	metabolic process	1	2
GO:0009056	catabolic process	2	2
GO:0009057	macromolecule catabolic process	4	2
GO:0009892	negative regulation of metabolic process	4	2
GO:0009987	cellular process	1	2
GO:0010468	regulation of gene expression	5	2
GO:0010605	negative regulation of macromolecule metabolic process	5	2
GO:0010629	negative regulation of gene expression	6	2
GO:0016070	RNA metabolic process	5	2
GO:0016071	mRNA metabolic process	6	2
GO:0019222	regulation of metabolic process	3	2
GO:0019439	aromatic compound catabolic process	4	2
GO:0034641	cellular nitrogen compound metabolic process	3	2
GO:0034655	nucleobase-containing compound catabolic process	4	2
GO:0043170	macromolecule metabolic process	3	2
GO:0044237	cellular metabolic process	2	2
GO:0044238	primary metabolic process	2	2
GO:0044248	cellular catabolic process	3	2
GO:0044260	obsolete cellular macromolecule metabolic process	3	2
GO:0044265	obsolete cellular macromolecule catabolic process	4	2
GO:0044270	cellular nitrogen compound catabolic process	4	2
GO:0046483	heterocycle metabolic process	3	2
GO:0046700	heterocycle catabolic process	4	2
GO:0048519	negative regulation of biological process	3	2
GO:0050789	regulation of biological process	2	2
GO:0060255	regulation of macromolecule metabolic process	4	2
GO:0065007	biological regulation	1	2
GO:0071704	organic substance metabolic process	2	2
GO:0090304	nucleic acid metabolic process	4	2
GO:1901360	organic cyclic compound metabolic process	3	2
GO:1901361	organic cyclic compound catabolic process	4	2
GO:1901575	organic substance catabolic process	3	2

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	9
GO:0003723	RNA binding	4	2
GO:0003824	catalytic activity	1	9
GO:0004518	nuclease activity	4	9
GO:0004527	exonuclease activity	5	9
GO:0004532	RNA exonuclease activity	5	2
GO:0004534	5'-3' RNA exonuclease activity	7	2
GO:0004540	RNA nuclease activity	4	2
GO:0005488	binding	1	9
GO:0008409	5'-3' exonuclease activity	6	2
GO:0016787	hydrolase activity	2	9
GO:0016788	hydrolase activity, acting on ester bonds	3	9
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6	2
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	6	2
GO:0097159	organic cyclic compound binding	2	9
GO:0140098	catalytic activity, acting on RNA	3	2
GO:0140640	catalytic activity, acting on a nucleic acid	2	2
GO:1901363	heterocyclic compound binding	2	9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	359	363	PF00656	0.444
CLV_C14_Caspase3-7	47	51	PF00656	0.684
CLV_C14_Caspase3-7	717	721	PF00656	0.670
CLV_NRD_NRD_1	173	175	PF00675	0.302
CLV_NRD_NRD_1	220	222	PF00675	0.525
CLV_NRD_NRD_1	271	273	PF00675	0.703
CLV_NRD_NRD_1	279	281	PF00675	0.762
CLV_NRD_NRD_1	34	36	PF00675	0.650
CLV_NRD_NRD_1	401	403	PF00675	0.498
CLV_NRD_NRD_1	592	594	PF00675	0.615
CLV_NRD_NRD_1	6	8	PF00675	0.431
CLV_NRD_NRD_1	750	752	PF00675	0.607
CLV_NRD_NRD_1	76	78	PF00675	0.776
CLV_NRD_NRD_1	781	783	PF00675	0.550
CLV_NRD_NRD_1	785	787	PF00675	0.536
CLV_NRD_NRD_1	806	808	PF00675	0.681
CLV_NRD_NRD_1	896	898	PF00675	0.810
CLV_NRD_NRD_1	929	931	PF00675	0.755
CLV_NRD_NRD_1	957	959	PF00675	0.654
CLV_NRD_NRD_1	981	983	PF00675	0.716
CLV_PCSK_FUR_1	170	174	PF00082	0.301
CLV_PCSK_FUR_1	269	273	PF00082	0.589
CLV_PCSK_FUR_1	955	959	PF00082	0.667
CLV_PCSK_KEX2_1	172	174	PF00082	0.301
CLV_PCSK_KEX2_1	220	222	PF00082	0.525
CLV_PCSK_KEX2_1	271	273	PF00082	0.703
CLV_PCSK_KEX2_1	279	281	PF00082	0.762
CLV_PCSK_KEX2_1	33	35	PF00082	0.650
CLV_PCSK_KEX2_1	401	403	PF00082	0.412
CLV_PCSK_KEX2_1	591	593	PF00082	0.557
CLV_PCSK_KEX2_1	733	735	PF00082	0.733
CLV_PCSK_KEX2_1	75	77	PF00082	0.786
CLV_PCSK_KEX2_1	781	783	PF00082	0.550
CLV_PCSK_KEX2_1	785	787	PF00082	0.536
CLV_PCSK_KEX2_1	954	956	PF00082	0.680
CLV_PCSK_KEX2_1	957	959	PF00082	0.686
CLV_PCSK_KEX2_1	979	981	PF00082	0.722
CLV_PCSK_PC1ET2_1	33	35	PF00082	0.700
CLV_PCSK_PC1ET2_1	733	735	PF00082	0.725
CLV_PCSK_PC1ET2_1	954	956	PF00082	0.646
CLV_PCSK_PC1ET2_1	979	981	PF00082	0.766
CLV_PCSK_PC7_1	216	222	PF00082	0.492
CLV_PCSK_PC7_1	72	78	PF00082	0.796
CLV_PCSK_PC7_1	781	787	PF00082	0.624
CLV_PCSK_SKI1_1	216	220	PF00082	0.448
CLV_PCSK_SKI1_1	351	355	PF00082	0.528
CLV_PCSK_SKI1_1	556	560	PF00082	0.561
CLV_PCSK_SKI1_1	577	581	PF00082	0.454
CLV_PCSK_SKI1_1	619	623	PF00082	0.531
CLV_PCSK_SKI1_1	691	695	PF00082	0.759
CLV_PCSK_SKI1_1	77	81	PF00082	0.752
CLV_PCSK_SKI1_1	799	803	PF00082	0.631
CLV_PCSK_SKI1_1	826	830	PF00082	0.480
CLV_PCSK_SKI1_1	872	876	PF00082	0.790
CLV_PCSK_SKI1_1	898	902	PF00082	0.731
DEG_SCF_TRCP1_1	52	58	PF00400	0.549
DEG_SPOP_SBC_1	78	82	PF00917	0.770
DOC_ANK_TNKS_1	34	41	PF00023	0.667
DOC_CDC14_PxL_1	629	637	PF14671	0.547
DOC_CKS1_1	507	512	PF01111	0.401
DOC_CKS1_1	775	780	PF01111	0.680
DOC_CKS1_1	971	976	PF01111	0.732
DOC_CYCLIN_RxL_1	14	25	PF00134	0.390
DOC_CYCLIN_yCln2_LP_2	630	636	PF00134	0.548
DOC_MAPK_gen_1	170	178	PF00069	0.525
DOC_MAPK_gen_1	220	227	PF00069	0.484
DOC_MAPK_gen_1	303	312	PF00069	0.562
DOC_MAPK_gen_1	556	564	PF00069	0.572
DOC_MAPK_MEF2A_6	150	157	PF00069	0.533
DOC_MAPK_MEF2A_6	374	382	PF00069	0.421
DOC_MAPK_RevD_3	161	175	PF00069	0.560
DOC_PP1_RVXF_1	240	247	PF00149	0.428
DOC_PP1_RVXF_1	372	378	PF00149	0.367
DOC_PP1_RVXF_1	637	644	PF00149	0.485
DOC_PP1_SILK_1	539	544	PF00149	0.543
DOC_PP2B_LxvP_1	19	22	PF13499	0.526
DOC_PP2B_LxvP_1	630	633	PF13499	0.535
DOC_PP4_FxxP_1	157	160	PF00568	0.560
DOC_PP4_FxxP_1	579	582	PF00568	0.464
DOC_PP4_FxxP_1	643	646	PF00568	0.431
DOC_PP4_FxxP_1	775	778	PF00568	0.678
DOC_USP7_MATH_1	149	153	PF00917	0.503
DOC_USP7_MATH_1	205	209	PF00917	0.476
DOC_USP7_MATH_1	248	252	PF00917	0.593
DOC_USP7_MATH_1	267	271	PF00917	0.471
DOC_USP7_MATH_1	411	415	PF00917	0.333
DOC_USP7_MATH_1	537	541	PF00917	0.523
DOC_USP7_MATH_1	707	711	PF00917	0.757
DOC_USP7_MATH_1	78	82	PF00917	0.775
DOC_USP7_MATH_1	840	844	PF00917	0.659
DOC_USP7_UBL2_3	867	871	PF12436	0.789
DOC_WW_Pin1_4	258	263	PF00397	0.763
DOC_WW_Pin1_4	363	368	PF00397	0.509
DOC_WW_Pin1_4	414	419	PF00397	0.535
DOC_WW_Pin1_4	506	511	PF00397	0.409
DOC_WW_Pin1_4	578	583	PF00397	0.500
DOC_WW_Pin1_4	697	702	PF00397	0.732
DOC_WW_Pin1_4	774	779	PF00397	0.691
DOC_WW_Pin1_4	831	836	PF00397	0.666
DOC_WW_Pin1_4	97	102	PF00397	0.510
DOC_WW_Pin1_4	970	975	PF00397	0.735
LIG_14-3-3_CanoR_1	140	149	PF00244	0.560
LIG_14-3-3_CanoR_1	150	154	PF00244	0.560
LIG_14-3-3_CanoR_1	173	179	PF00244	0.525
LIG_14-3-3_CanoR_1	344	352	PF00244	0.477
LIG_14-3-3_CanoR_1	407	411	PF00244	0.441
LIG_14-3-3_CanoR_1	577	582	PF00244	0.547
LIG_14-3-3_CanoR_1	601	611	PF00244	0.492
LIG_14-3-3_CanoR_1	619	624	PF00244	0.590
LIG_14-3-3_CanoR_1	667	673	PF00244	0.684
LIG_14-3-3_CanoR_1	686	695	PF00244	0.761
LIG_14-3-3_CanoR_1	751	758	PF00244	0.557
LIG_14-3-3_CanoR_1	76	85	PF00244	0.752
LIG_14-3-3_CanoR_1	812	821	PF00244	0.634
LIG_14-3-3_CanoR_1	933	937	PF00244	0.738
LIG_Actin_WH2_2	338	356	PF00022	0.495
LIG_BIR_III_2	832	836	PF00653	0.659
LIG_BRCT_BRCA1_1	153	157	PF00533	0.560
LIG_Clathr_ClatBox_1	197	201	PF01394	0.413
LIG_eIF4E_1	410	416	PF01652	0.507
LIG_FHA_1	14	20	PF00498	0.484
LIG_FHA_1	142	148	PF00498	0.512
LIG_FHA_1	166	172	PF00498	0.538
LIG_FHA_1	179	185	PF00498	0.577
LIG_FHA_1	187	193	PF00498	0.506
LIG_FHA_1	307	313	PF00498	0.409
LIG_FHA_1	549	555	PF00498	0.529
LIG_FHA_1	578	584	PF00498	0.464
LIG_FHA_1	636	642	PF00498	0.533
LIG_FHA_1	763	769	PF00498	0.514
LIG_FHA_1	98	104	PF00498	0.523
LIG_FHA_2	259	265	PF00498	0.731
LIG_FHA_2	357	363	PF00498	0.565
LIG_FHA_2	43	49	PF00498	0.656
LIG_FHA_2	507	513	PF00498	0.413
LIG_FHA_2	545	551	PF00498	0.539
LIG_FHA_2	568	574	PF00498	0.455
LIG_FHA_2	620	626	PF00498	0.479
LIG_FHA_2	698	704	PF00498	0.707
LIG_FHA_2	712	718	PF00498	0.552
LIG_FHA_2	902	908	PF00498	0.731
LIG_FHA_2	909	915	PF00498	0.714
LIG_FHA_2	971	977	PF00498	0.747
LIG_Integrin_isoDGR_2	291	293	PF01839	0.527
LIG_Integrin_RGD_1	360	362	PF01839	0.618
LIG_LIR_Apic_2	154	160	PF02991	0.560
LIG_LIR_Apic_2	642	646	PF02991	0.444
LIG_LIR_Gen_1	327	337	PF02991	0.375
LIG_LIR_Gen_1	376	383	PF02991	0.363
LIG_LIR_Gen_1	466	476	PF02991	0.483
LIG_LIR_Gen_1	512	522	PF02991	0.464
LIG_LIR_Gen_1	605	616	PF02991	0.556
LIG_LIR_Gen_1	638	647	PF02991	0.499
LIG_LIR_Nem_3	327	332	PF02991	0.375
LIG_LIR_Nem_3	347	353	PF02991	0.375
LIG_LIR_Nem_3	376	382	PF02991	0.363
LIG_LIR_Nem_3	39	44	PF02991	0.669
LIG_LIR_Nem_3	466	471	PF02991	0.434
LIG_LIR_Nem_3	512	517	PF02991	0.449
LIG_LIR_Nem_3	605	611	PF02991	0.558
LIG_LIR_Nem_3	638	643	PF02991	0.514
LIG_Pex14_2	377	381	PF04695	0.365
LIG_Pex14_2	643	647	PF04695	0.441
LIG_PTB_Apo_2	628	635	PF02174	0.536
LIG_PTB_Phospho_1	628	634	PF10480	0.532
LIG_SH2_CRK	403	407	PF00017	0.393
LIG_SH2_CRK	468	472	PF00017	0.433
LIG_SH2_GRB2like	57	60	PF00017	0.710
LIG_SH2_GRB2like	629	632	PF00017	0.522
LIG_SH2_GRB2like	736	739	PF00017	0.755
LIG_SH2_PTP2	514	517	PF00017	0.494
LIG_SH2_PTP2	608	611	PF00017	0.553
LIG_SH2_SRC	226	229	PF00017	0.399
LIG_SH2_SRC	470	473	PF00017	0.483
LIG_SH2_SRC	629	632	PF00017	0.491
LIG_SH2_STAP1	637	641	PF00017	0.542
LIG_SH2_STAP1	916	920	PF00017	0.806
LIG_SH2_STAT3	736	739	PF00017	0.701
LIG_SH2_STAT5	226	229	PF00017	0.399
LIG_SH2_STAT5	301	304	PF00017	0.570
LIG_SH2_STAT5	389	392	PF00017	0.457
LIG_SH2_STAT5	437	440	PF00017	0.469
LIG_SH2_STAT5	470	473	PF00017	0.486
LIG_SH2_STAT5	514	517	PF00017	0.491
LIG_SH2_STAT5	57	60	PF00017	0.666
LIG_SH2_STAT5	575	578	PF00017	0.507
LIG_SH2_STAT5	608	611	PF00017	0.553
LIG_SH2_STAT5	629	632	PF00017	0.465
LIG_SH2_STAT5	634	637	PF00017	0.504
LIG_SH2_STAT5	640	643	PF00017	0.497
LIG_SH2_STAT5	644	647	PF00017	0.478
LIG_SH2_STAT5	736	739	PF00017	0.695
LIG_SH2_STAT5	809	812	PF00017	0.657
LIG_SH2_STAT5	99	102	PF00017	0.461
LIG_SH3_3	143	149	PF00018	0.501
LIG_SH3_3	361	367	PF00018	0.575
LIG_SH3_3	468	474	PF00018	0.466
LIG_SH3_3	493	499	PF00018	0.526
LIG_SH3_3	504	510	PF00018	0.435
LIG_SH3_3	561	567	PF00018	0.514
LIG_SH3_3	584	590	PF00018	0.560
LIG_SH3_3	608	614	PF00018	0.491
LIG_SH3_3	630	636	PF00018	0.561
LIG_SH3_3	90	96	PF00018	0.523
LIG_SUMO_SIM_anti_2	307	316	PF11976	0.409
LIG_SUMO_SIM_par_1	188	193	PF11976	0.429
LIG_SUMO_SIM_par_1	198	203	PF11976	0.377
LIG_TRAF2_1	28	31	PF00917	0.689
LIG_TRAF2_1	963	966	PF00917	0.565
LIG_TYR_ITIM	348	353	PF00017	0.407
LIG_TYR_ITIM	627	632	PF00017	0.492
LIG_UBA3_1	3	8	PF00899	0.481
LIG_WRC_WIRS_1	961	966	PF05994	0.676
LIG_WW_3	588	592	PF00397	0.612
MOD_CDC14_SPxK_1	834	837	PF00782	0.430
MOD_CDK_SPxK_1	831	837	PF00069	0.434
MOD_CDK_SPxxK_3	697	704	PF00069	0.669
MOD_CDK_SPxxK_3	774	781	PF00069	0.688
MOD_CK1_1	251	257	PF00069	0.717
MOD_CK1_1	414	420	PF00069	0.339
MOD_CK1_1	435	441	PF00069	0.526
MOD_CK1_1	456	462	PF00069	0.384
MOD_CK1_1	548	554	PF00069	0.531
MOD_CK1_1	671	677	PF00069	0.646
MOD_CK1_1	710	716	PF00069	0.706
MOD_CK1_1	83	89	PF00069	0.732
MOD_CK1_1	865	871	PF00069	0.769
MOD_CK1_1	932	938	PF00069	0.794
MOD_CK2_1	21	27	PF00069	0.581
MOD_CK2_1	267	273	PF00069	0.715
MOD_CK2_1	438	444	PF00069	0.540
MOD_CK2_1	506	512	PF00069	0.434
MOD_CK2_1	567	573	PF00069	0.445
MOD_CK2_1	592	598	PF00069	0.524
MOD_CK2_1	619	625	PF00069	0.474
MOD_CK2_1	710	716	PF00069	0.681
MOD_CK2_1	83	89	PF00069	0.786
MOD_CK2_1	879	885	PF00069	0.682
MOD_CK2_1	908	914	PF00069	0.654
MOD_CK2_1	960	966	PF00069	0.775
MOD_CK2_1	970	976	PF00069	0.752
MOD_Cter_Amidation	277	280	PF01082	0.784
MOD_GlcNHglycan	250	253	PF01048	0.563
MOD_GlcNHglycan	282	285	PF01048	0.797
MOD_GlcNHglycan	356	359	PF01048	0.522
MOD_GlcNHglycan	451	454	PF01048	0.410
MOD_GlcNHglycan	52	55	PF01048	0.740
MOD_GlcNHglycan	563	567	PF01048	0.488
MOD_GlcNHglycan	59	62	PF01048	0.641
MOD_GlcNHglycan	664	667	PF01048	0.716
MOD_GlcNHglycan	670	673	PF01048	0.725
MOD_GlcNHglycan	695	698	PF01048	0.766
MOD_GlcNHglycan	709	712	PF01048	0.647
MOD_GlcNHglycan	752	755	PF01048	0.577
MOD_GlcNHglycan	765	768	PF01048	0.529
MOD_GlcNHglycan	794	797	PF01048	0.669
MOD_GlcNHglycan	864	867	PF01048	0.762
MOD_GlcNHglycan	881	884	PF01048	0.556
MOD_GlcNHglycan	947	952	PF01048	0.702
MOD_GSK3_1	120	127	PF00069	0.351
MOD_GSK3_1	174	181	PF00069	0.533
MOD_GSK3_1	186	193	PF00069	0.291
MOD_GSK3_1	251	258	PF00069	0.715
MOD_GSK3_1	365	372	PF00069	0.577
MOD_GSK3_1	406	413	PF00069	0.442
MOD_GSK3_1	431	438	PF00069	0.446
MOD_GSK3_1	449	456	PF00069	0.260
MOD_GSK3_1	459	466	PF00069	0.322
MOD_GSK3_1	502	509	PF00069	0.468
MOD_GSK3_1	520	527	PF00069	0.329
MOD_GSK3_1	537	544	PF00069	0.544
MOD_GSK3_1	667	674	PF00069	0.590
MOD_GSK3_1	693	700	PF00069	0.712
MOD_GSK3_1	707	714	PF00069	0.646
MOD_GSK3_1	79	86	PF00069	0.729
MOD_GSK3_1	861	868	PF00069	0.777
MOD_GSK3_1	9	16	PF00069	0.459
MOD_GSK3_1	966	973	PF00069	0.750
MOD_LATS_1	684	690	PF00433	0.686
MOD_N-GLC_1	124	129	PF02516	0.395
MOD_N-GLC_1	330	335	PF02516	0.453
MOD_N-GLC_1	548	553	PF02516	0.507
MOD_NEK2_1	178	183	PF00069	0.530
MOD_NEK2_1	190	195	PF00069	0.401
MOD_NEK2_1	227	232	PF00069	0.391
MOD_NEK2_1	319	324	PF00069	0.372
MOD_NEK2_1	353	358	PF00069	0.538
MOD_NEK2_1	449	454	PF00069	0.367
MOD_NEK2_1	602	607	PF00069	0.509
MOD_NEK2_1	693	698	PF00069	0.719
MOD_NEK2_1	705	710	PF00069	0.732
MOD_NEK2_1	762	767	PF00069	0.517
MOD_NEK2_1	79	84	PF00069	0.817
MOD_NEK2_1	9	14	PF00069	0.464
MOD_NEK2_1	920	925	PF00069	0.730
MOD_OFUCOSY	112	117	PF10250	0.423
MOD_PIKK_1	165	171	PF00454	0.357
MOD_PIKK_1	205	211	PF00454	0.479
MOD_PIKK_1	365	371	PF00454	0.568
MOD_PIKK_1	502	508	PF00454	0.554
MOD_PIKK_1	649	655	PF00454	0.594
MOD_PKA_1	174	180	PF00069	0.391
MOD_PKA_1	279	285	PF00069	0.708
MOD_PKA_1	592	598	PF00069	0.524
MOD_PKA_2	149	155	PF00069	0.438
MOD_PKA_2	279	285	PF00069	0.708
MOD_PKA_2	343	349	PF00069	0.463
MOD_PKA_2	406	412	PF00069	0.483
MOD_PKA_2	592	598	PF00069	0.524
MOD_PKA_2	678	684	PF00069	0.744
MOD_PKA_2	750	756	PF00069	0.564
MOD_PKA_2	929	935	PF00069	0.832
MOD_PKB_1	172	180	PF00069	0.391
MOD_PKB_1	75	83	PF00069	0.766
MOD_PKB_1	958	966	PF00069	0.671
MOD_PKB_1	970	978	PF00069	0.565
MOD_Plk_1	306	312	PF00069	0.419
MOD_Plk_1	330	336	PF00069	0.475
MOD_Plk_1	520	526	PF00069	0.458
MOD_Plk_2-3	712	718	PF00069	0.762
MOD_Plk_4	174	180	PF00069	0.391
MOD_Plk_4	193	199	PF00069	0.401
MOD_Plk_4	228	234	PF00069	0.452
MOD_Plk_4	306	312	PF00069	0.439
MOD_Plk_4	411	417	PF00069	0.501
MOD_Plk_4	456	462	PF00069	0.392
MOD_Plk_4	537	543	PF00069	0.541
MOD_ProDKin_1	258	264	PF00069	0.764
MOD_ProDKin_1	363	369	PF00069	0.500
MOD_ProDKin_1	414	420	PF00069	0.531
MOD_ProDKin_1	506	512	PF00069	0.409
MOD_ProDKin_1	578	584	PF00069	0.498
MOD_ProDKin_1	697	703	PF00069	0.731
MOD_ProDKin_1	774	780	PF00069	0.688
MOD_ProDKin_1	831	837	PF00069	0.667
MOD_ProDKin_1	97	103	PF00069	0.497
MOD_ProDKin_1	970	976	PF00069	0.734
MOD_SUMO_rev_2	122	127	PF00179	0.434
MOD_SUMO_rev_2	235	241	PF00179	0.388
MOD_SUMO_rev_2	744	754	PF00179	0.705
MOD_SUMO_rev_2	805	810	PF00179	0.678
TRG_DiLeu_BaEn_2	823	829	PF01217	0.585
TRG_DiLeu_BaLyEn_6	14	19	PF01217	0.522
TRG_ENDOCYTIC_2	350	353	PF00928	0.396
TRG_ENDOCYTIC_2	403	406	PF00928	0.396
TRG_ENDOCYTIC_2	41	44	PF00928	0.681
TRG_ENDOCYTIC_2	468	471	PF00928	0.434
TRG_ENDOCYTIC_2	514	517	PF00928	0.494
TRG_ENDOCYTIC_2	608	611	PF00928	0.553
TRG_ENDOCYTIC_2	629	632	PF00928	0.457
TRG_ENDOCYTIC_2	640	643	PF00928	0.586
TRG_ENDOCYTIC_2	644	647	PF00928	0.498
TRG_ENDOCYTIC_2	99	102	PF00928	0.564
TRG_ER_diArg_1	138	141	PF00400	0.391
TRG_ER_diArg_1	170	173	PF00400	0.357
TRG_ER_diArg_1	219	221	PF00400	0.498
TRG_ER_diArg_1	268	271	PF00400	0.643
TRG_ER_diArg_1	302	305	PF00400	0.561
TRG_ER_diArg_1	34	37	PF00400	0.653
TRG_ER_diArg_1	400	402	PF00400	0.501
TRG_ER_diArg_1	590	593	PF00400	0.637
TRG_ER_diArg_1	746	749	PF00400	0.678
TRG_ER_diArg_1	75	77	PF00400	0.809
TRG_ER_diArg_1	781	783	PF00400	0.552
TRG_ER_diArg_1	785	787	PF00400	0.538
TRG_ER_diArg_1	887	890	PF00400	0.590
TRG_ER_diArg_1	955	958	PF00400	0.689
TRG_ER_diArg_1	980	982	PF00400	0.772
TRG_NES_CRM1_1	130	145	PF08389	0.438
TRG_NES_CRM1_1	506	521	PF08389	0.503
TRG_NLS_MonoCore_2	953	958	PF00514	0.654
TRG_NLS_MonoCore_2	977	982	PF00514	0.815
TRG_NLS_MonoExtC_3	32	37	PF00514	0.701
TRG_NLS_MonoExtC_3	953	958	PF00514	0.656
TRG_NLS_MonoExtC_3	977	982	PF00514	0.815
TRG_NLS_MonoExtN_4	928	934	PF00514	0.742
TRG_NLS_MonoExtN_4	978	983	PF00514	0.815
TRG_Pf-PMV_PEXEL_1	140	145	PF00026	0.398
TRG_Pf-PMV_PEXEL_1	34	39	PF00026	0.641
TRG_Pf-PMV_PEXEL_1	819	824	PF00026	0.578

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IM29	Leptomonas seymouri	65%	100%
A0A1X0NZ48	Trypanosomatidae	45%	100%
A0A3S7WTU7	Leishmania donovani	89%	98%
A4H8G4	Leishmania braziliensis	78%	99%
A4HWT8	Leishmania infantum	89%	98%
C9ZPR7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	100%
E9AQJ6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%