LeishMANIAdb
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LysM domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
LysM domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QEU9_LEIMA
TriTrypDb:
LmjF.16.0700 , LMJLV39_160012500 * , LMJSD75_160012300
Length:
849

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QEU9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QEU9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 427 431 PF00656 0.747
CLV_NRD_NRD_1 185 187 PF00675 0.636
CLV_NRD_NRD_1 403 405 PF00675 0.587
CLV_NRD_NRD_1 692 694 PF00675 0.730
CLV_NRD_NRD_1 818 820 PF00675 0.741
CLV_PCSK_KEX2_1 185 187 PF00082 0.649
CLV_PCSK_KEX2_1 403 405 PF00082 0.587
CLV_PCSK_KEX2_1 5 7 PF00082 0.549
CLV_PCSK_KEX2_1 692 694 PF00082 0.730
CLV_PCSK_PC1ET2_1 5 7 PF00082 0.499
CLV_PCSK_SKI1_1 359 363 PF00082 0.582
CLV_PCSK_SKI1_1 455 459 PF00082 0.686
CLV_PCSK_SKI1_1 685 689 PF00082 0.677
CLV_Separin_Metazoa 816 820 PF03568 0.658
DEG_APCC_DBOX_1 283 291 PF00400 0.678
DEG_COP1_1 242 251 PF00400 0.644
DEG_Nend_UBRbox_2 1 3 PF02207 0.577
DEG_ODPH_VHL_1 464 477 PF01847 0.587
DEG_SCF_TRCP1_1 237 243 PF00400 0.724
DEG_SPOP_SBC_1 190 194 PF00917 0.714
DEG_SPOP_SBC_1 596 600 PF00917 0.746
DOC_CKS1_1 577 582 PF01111 0.737
DOC_MAPK_DCC_7 244 253 PF00069 0.640
DOC_MAPK_MEF2A_6 244 253 PF00069 0.640
DOC_MAPK_MEF2A_6 702 709 PF00069 0.658
DOC_PP2B_LxvP_1 251 254 PF13499 0.652
DOC_PP2B_LxvP_1 537 540 PF13499 0.663
DOC_PP2B_LxvP_1 718 721 PF13499 0.670
DOC_PP4_FxxP_1 577 580 PF00568 0.734
DOC_PP4_FxxP_1 687 690 PF00568 0.775
DOC_PP4_MxPP_1 649 652 PF00568 0.737
DOC_USP7_MATH_1 129 133 PF00917 0.642
DOC_USP7_MATH_1 190 194 PF00917 0.809
DOC_USP7_MATH_1 206 210 PF00917 0.534
DOC_USP7_MATH_1 219 223 PF00917 0.605
DOC_USP7_MATH_1 311 315 PF00917 0.754
DOC_USP7_MATH_1 318 322 PF00917 0.508
DOC_USP7_MATH_1 393 397 PF00917 0.659
DOC_USP7_MATH_1 417 421 PF00917 0.665
DOC_USP7_MATH_1 473 477 PF00917 0.633
DOC_USP7_MATH_1 538 542 PF00917 0.704
DOC_USP7_MATH_1 559 563 PF00917 0.795
DOC_USP7_MATH_1 565 569 PF00917 0.729
DOC_USP7_MATH_1 596 600 PF00917 0.743
DOC_USP7_MATH_1 612 616 PF00917 0.699
DOC_USP7_MATH_1 635 639 PF00917 0.661
DOC_USP7_MATH_1 669 673 PF00917 0.680
DOC_USP7_MATH_1 794 798 PF00917 0.628
DOC_USP7_MATH_2 34 40 PF00917 0.587
DOC_USP7_MATH_2 540 546 PF00917 0.575
DOC_WW_Pin1_4 242 247 PF00397 0.724
DOC_WW_Pin1_4 277 282 PF00397 0.659
DOC_WW_Pin1_4 295 300 PF00397 0.524
DOC_WW_Pin1_4 321 326 PF00397 0.629
DOC_WW_Pin1_4 330 335 PF00397 0.606
DOC_WW_Pin1_4 339 344 PF00397 0.530
DOC_WW_Pin1_4 348 353 PF00397 0.670
DOC_WW_Pin1_4 380 385 PF00397 0.725
DOC_WW_Pin1_4 409 414 PF00397 0.616
DOC_WW_Pin1_4 465 470 PF00397 0.727
DOC_WW_Pin1_4 478 483 PF00397 0.691
DOC_WW_Pin1_4 519 524 PF00397 0.724
DOC_WW_Pin1_4 531 536 PF00397 0.601
DOC_WW_Pin1_4 570 575 PF00397 0.718
DOC_WW_Pin1_4 576 581 PF00397 0.704
DOC_WW_Pin1_4 605 610 PF00397 0.832
DOC_WW_Pin1_4 613 618 PF00397 0.729
DOC_WW_Pin1_4 627 632 PF00397 0.661
DOC_WW_Pin1_4 643 648 PF00397 0.651
DOC_WW_Pin1_4 658 663 PF00397 0.577
DOC_WW_Pin1_4 694 699 PF00397 0.668
DOC_WW_Pin1_4 709 714 PF00397 0.714
DOC_WW_Pin1_4 719 724 PF00397 0.639
DOC_WW_Pin1_4 826 831 PF00397 0.735
DOC_WW_Pin1_4 839 844 PF00397 0.571
LIG_14-3-3_CanoR_1 128 137 PF00244 0.665
LIG_14-3-3_CanoR_1 138 143 PF00244 0.642
LIG_14-3-3_CanoR_1 403 410 PF00244 0.709
LIG_14-3-3_CanoR_1 423 429 PF00244 0.555
LIG_14-3-3_CanoR_1 47 54 PF00244 0.544
LIG_14-3-3_CanoR_1 491 499 PF00244 0.698
LIG_14-3-3_CanoR_1 657 662 PF00244 0.684
LIG_14-3-3_CanoR_1 678 683 PF00244 0.700
LIG_14-3-3_CanoR_1 685 690 PF00244 0.613
LIG_BRCT_BRCA1_1 214 218 PF00533 0.642
LIG_BRCT_BRCA1_1 332 336 PF00533 0.554
LIG_CtBP_PxDLS_1 663 667 PF00389 0.731
LIG_CtBP_PxDLS_1 715 719 PF00389 0.674
LIG_EVH1_1 322 326 PF00568 0.609
LIG_EVH1_2 683 687 PF00568 0.631
LIG_FHA_1 387 393 PF00498 0.597
LIG_FHA_1 804 810 PF00498 0.649
LIG_FHA_2 30 36 PF00498 0.581
LIG_FHA_2 766 772 PF00498 0.362
LIG_GBD_Chelix_1 37 45 PF00786 0.481
LIG_IBAR_NPY_1 773 775 PF08397 0.412
LIG_LIR_Apic_2 575 580 PF02991 0.729
LIG_LIR_Gen_1 122 131 PF02991 0.579
LIG_LIR_Gen_1 733 741 PF02991 0.683
LIG_LIR_Gen_1 750 760 PF02991 0.445
LIG_LIR_Gen_1 9 20 PF02991 0.518
LIG_LIR_Nem_3 122 127 PF02991 0.557
LIG_LIR_Nem_3 283 288 PF02991 0.623
LIG_LIR_Nem_3 733 737 PF02991 0.714
LIG_LIR_Nem_3 750 755 PF02991 0.671
LIG_LIR_Nem_3 771 775 PF02991 0.412
LIG_LIR_Nem_3 9 15 PF02991 0.494
LIG_Pex14_1 353 357 PF04695 0.772
LIG_SH2_CRK 12 16 PF00017 0.504
LIG_SH2_STAT5 124 127 PF00017 0.548
LIG_SH2_STAT5 286 289 PF00017 0.628
LIG_SH2_STAT5 775 778 PF00017 0.412
LIG_SH3_1 382 388 PF00018 0.654
LIG_SH3_2 450 455 PF14604 0.559
LIG_SH3_2 466 471 PF14604 0.532
LIG_SH3_3 104 110 PF00018 0.546
LIG_SH3_3 115 121 PF00018 0.648
LIG_SH3_3 243 249 PF00018 0.721
LIG_SH3_3 275 281 PF00018 0.603
LIG_SH3_3 320 326 PF00018 0.759
LIG_SH3_3 331 337 PF00018 0.681
LIG_SH3_3 382 388 PF00018 0.672
LIG_SH3_3 447 453 PF00018 0.620
LIG_SH3_3 463 469 PF00018 0.612
LIG_SH3_3 477 483 PF00018 0.798
LIG_SH3_3 577 583 PF00018 0.611
LIG_SH3_3 656 662 PF00018 0.799
LIG_SH3_3 692 698 PF00018 0.723
LIG_SH3_3 710 716 PF00018 0.624
LIG_SH3_3 720 726 PF00018 0.661
LIG_SH3_3 781 787 PF00018 0.619
LIG_SH3_3 842 848 PF00018 0.620
LIG_SUMO_SIM_par_1 16 21 PF11976 0.535
LIG_SUMO_SIM_par_1 286 293 PF11976 0.683
LIG_SUMO_SIM_par_1 326 333 PF11976 0.594
LIG_TRAF2_1 371 374 PF00917 0.664
LIG_TYR_ITIM 10 15 PF00017 0.495
LIG_UBA3_1 287 291 PF00899 0.685
LIG_WW_3 452 456 PF00397 0.635
LIG_WW_3 682 686 PF00397 0.695
LIG_WW_3 689 693 PF00397 0.646
MOD_CDC14_SPxK_1 468 471 PF00782 0.730
MOD_CDK_SPK_2 627 632 PF00069 0.713
MOD_CDK_SPxK_1 465 471 PF00069 0.730
MOD_CDK_SPxK_1 841 847 PF00069 0.628
MOD_CDK_SPxxK_3 277 284 PF00069 0.614
MOD_CDK_SPxxK_3 643 650 PF00069 0.737
MOD_CK1_1 132 138 PF00069 0.695
MOD_CK1_1 140 146 PF00069 0.669
MOD_CK1_1 155 161 PF00069 0.607
MOD_CK1_1 164 170 PF00069 0.657
MOD_CK1_1 189 195 PF00069 0.811
MOD_CK1_1 196 202 PF00069 0.688
MOD_CK1_1 232 238 PF00069 0.770
MOD_CK1_1 242 248 PF00069 0.660
MOD_CK1_1 273 279 PF00069 0.629
MOD_CK1_1 297 303 PF00069 0.729
MOD_CK1_1 321 327 PF00069 0.653
MOD_CK1_1 329 335 PF00069 0.681
MOD_CK1_1 367 373 PF00069 0.728
MOD_CK1_1 396 402 PF00069 0.662
MOD_CK1_1 478 484 PF00069 0.718
MOD_CK1_1 494 500 PF00069 0.585
MOD_CK1_1 541 547 PF00069 0.733
MOD_CK1_1 557 563 PF00069 0.602
MOD_CK1_1 608 614 PF00069 0.821
MOD_CK1_1 630 636 PF00069 0.744
MOD_CK1_1 672 678 PF00069 0.705
MOD_CK1_1 69 75 PF00069 0.770
MOD_CK2_1 368 374 PF00069 0.727
MOD_CK2_1 600 606 PF00069 0.678
MOD_CK2_1 618 624 PF00069 0.576
MOD_CK2_1 630 636 PF00069 0.613
MOD_CK2_1 719 725 PF00069 0.755
MOD_CK2_1 765 771 PF00069 0.362
MOD_CK2_1 794 800 PF00069 0.616
MOD_CK2_1 87 93 PF00069 0.484
MOD_Cter_Amidation 401 404 PF01082 0.589
MOD_GlcNHglycan 158 161 PF01048 0.737
MOD_GlcNHglycan 163 166 PF01048 0.697
MOD_GlcNHglycan 167 170 PF01048 0.626
MOD_GlcNHglycan 188 191 PF01048 0.710
MOD_GlcNHglycan 214 217 PF01048 0.645
MOD_GlcNHglycan 231 234 PF01048 0.659
MOD_GlcNHglycan 237 240 PF01048 0.772
MOD_GlcNHglycan 370 373 PF01048 0.594
MOD_GlcNHglycan 38 41 PF01048 0.505
MOD_GlcNHglycan 444 447 PF01048 0.716
MOD_GlcNHglycan 477 480 PF01048 0.731
MOD_GlcNHglycan 493 496 PF01048 0.595
MOD_GlcNHglycan 567 570 PF01048 0.638
MOD_GlcNHglycan 610 613 PF01048 0.737
MOD_GlcNHglycan 620 623 PF01048 0.639
MOD_GlcNHglycan 671 674 PF01048 0.669
MOD_GlcNHglycan 68 71 PF01048 0.636
MOD_GlcNHglycan 835 838 PF01048 0.697
MOD_GSK3_1 129 136 PF00069 0.678
MOD_GSK3_1 137 144 PF00069 0.704
MOD_GSK3_1 152 159 PF00069 0.573
MOD_GSK3_1 161 168 PF00069 0.668
MOD_GSK3_1 186 193 PF00069 0.760
MOD_GSK3_1 196 203 PF00069 0.706
MOD_GSK3_1 235 242 PF00069 0.733
MOD_GSK3_1 249 256 PF00069 0.575
MOD_GSK3_1 273 280 PF00069 0.721
MOD_GSK3_1 326 333 PF00069 0.649
MOD_GSK3_1 364 371 PF00069 0.835
MOD_GSK3_1 374 381 PF00069 0.692
MOD_GSK3_1 393 400 PF00069 0.549
MOD_GSK3_1 409 416 PF00069 0.597
MOD_GSK3_1 467 474 PF00069 0.706
MOD_GSK3_1 478 485 PF00069 0.669
MOD_GSK3_1 538 545 PF00069 0.719
MOD_GSK3_1 555 562 PF00069 0.669
MOD_GSK3_1 572 579 PF00069 0.726
MOD_GSK3_1 596 603 PF00069 0.736
MOD_GSK3_1 608 615 PF00069 0.735
MOD_GSK3_1 69 76 PF00069 0.703
MOD_N-GLC_1 439 444 PF02516 0.597
MOD_N-GLC_1 664 669 PF02516 0.732
MOD_N-GLC_1 762 767 PF02516 0.412
MOD_N-GLC_1 826 831 PF02516 0.710
MOD_N-GLC_2 255 257 PF02516 0.647
MOD_NEK2_1 524 529 PF00069 0.577
MOD_NEK2_1 597 602 PF00069 0.748
MOD_NEK2_1 764 769 PF00069 0.362
MOD_NEK2_1 95 100 PF00069 0.513
MOD_PIKK_1 168 174 PF00454 0.670
MOD_PIKK_1 224 230 PF00454 0.723
MOD_PIKK_1 524 530 PF00454 0.618
MOD_PIKK_1 724 730 PF00454 0.628
MOD_PK_1 138 144 PF00069 0.545
MOD_PK_1 471 477 PF00069 0.666
MOD_PKA_2 137 143 PF00069 0.646
MOD_PKA_2 194 200 PF00069 0.659
MOD_PKA_2 229 235 PF00069 0.797
MOD_PKA_2 239 245 PF00069 0.648
MOD_PKA_2 402 408 PF00069 0.748
MOD_PKA_2 46 52 PF00069 0.538
MOD_PKA_2 66 72 PF00069 0.676
MOD_PKA_2 677 683 PF00069 0.662
MOD_PKB_1 376 384 PF00069 0.619
MOD_PKB_1 421 429 PF00069 0.595
MOD_Plk_1 249 255 PF00069 0.652
MOD_Plk_1 471 477 PF00069 0.666
MOD_Plk_1 635 641 PF00069 0.588
MOD_Plk_1 762 768 PF00069 0.438
MOD_Plk_2-3 751 757 PF00069 0.362
MOD_Plk_4 120 126 PF00069 0.573
MOD_Plk_4 393 399 PF00069 0.584
MOD_Plk_4 765 771 PF00069 0.362
MOD_ProDKin_1 242 248 PF00069 0.724
MOD_ProDKin_1 277 283 PF00069 0.660
MOD_ProDKin_1 295 301 PF00069 0.516
MOD_ProDKin_1 321 327 PF00069 0.633
MOD_ProDKin_1 330 336 PF00069 0.605
MOD_ProDKin_1 339 345 PF00069 0.532
MOD_ProDKin_1 348 354 PF00069 0.668
MOD_ProDKin_1 380 386 PF00069 0.726
MOD_ProDKin_1 409 415 PF00069 0.618
MOD_ProDKin_1 465 471 PF00069 0.729
MOD_ProDKin_1 478 484 PF00069 0.692
MOD_ProDKin_1 519 525 PF00069 0.726
MOD_ProDKin_1 531 537 PF00069 0.602
MOD_ProDKin_1 570 576 PF00069 0.720
MOD_ProDKin_1 605 611 PF00069 0.834
MOD_ProDKin_1 613 619 PF00069 0.727
MOD_ProDKin_1 627 633 PF00069 0.660
MOD_ProDKin_1 643 649 PF00069 0.651
MOD_ProDKin_1 658 664 PF00069 0.575
MOD_ProDKin_1 694 700 PF00069 0.670
MOD_ProDKin_1 709 715 PF00069 0.705
MOD_ProDKin_1 719 725 PF00069 0.639
MOD_ProDKin_1 826 832 PF00069 0.735
MOD_ProDKin_1 839 845 PF00069 0.568
TRG_DiLeu_BaEn_1 805 810 PF01217 0.606
TRG_ENDOCYTIC_2 12 15 PF00928 0.512
TRG_ENDOCYTIC_2 124 127 PF00928 0.548
TRG_ENDOCYTIC_2 285 288 PF00928 0.625
TRG_ENDOCYTIC_2 752 755 PF00928 0.412
TRG_ER_diArg_1 148 151 PF00400 0.710
TRG_ER_diArg_1 375 378 PF00400 0.623
TRG_ER_diArg_1 421 424 PF00400 0.620
TRG_ER_diArg_1 438 441 PF00400 0.684
TRG_ER_diArg_1 583 586 PF00400 0.612
TRG_ER_diArg_1 691 693 PF00400 0.717
TRG_NES_CRM1_1 86 101 PF08389 0.510
TRG_NLS_MonoExtC_3 550 555 PF00514 0.581

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IJ04 Leishmania donovani 87% 100%
A4H8J2 Leishmania braziliensis 60% 99%
A4HWW7 Leishmania infantum 87% 100%
E9AQM9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS