LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QEU8_LEIMA
TriTrypDb:
LmjF.16.0710 * , LMJLV39_160012600 * , LMJSD75_160012400
Length:
1009

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QEU8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QEU8

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 500 504 PF00656 0.662
CLV_C14_Caspase3-7 548 552 PF00656 0.720
CLV_C14_Caspase3-7 603 607 PF00656 0.712
CLV_NRD_NRD_1 1006 1008 PF00675 0.730
CLV_NRD_NRD_1 214 216 PF00675 0.789
CLV_NRD_NRD_1 242 244 PF00675 0.786
CLV_NRD_NRD_1 323 325 PF00675 0.734
CLV_NRD_NRD_1 328 330 PF00675 0.762
CLV_NRD_NRD_1 338 340 PF00675 0.663
CLV_NRD_NRD_1 367 369 PF00675 0.789
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S7WU41 Leishmania donovani 86% 100%
A4H8J3 Leishmania braziliensis 59% 98%
A4HWW8 Leishmania infantum 86% 100%
E9AQN0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 81% 97%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS