Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QES9_LEIMA

TriTrypDb:

LmjF.16.0895 , LMJLV39_160014700 , LMJSD75_160014500

Length:

298

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QES9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QES9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	193	195	PF00675	0.625
CLV_NRD_NRD_1	205	207	PF00675	0.685
CLV_NRD_NRD_1	30	32	PF00675	0.560
CLV_NRD_NRD_1	99	101	PF00675	0.507
CLV_PCSK_KEX2_1	192	194	PF00082	0.629
CLV_PCSK_KEX2_1	205	207	PF00082	0.678
CLV_PCSK_KEX2_1	30	32	PF00082	0.578
CLV_PCSK_KEX2_1	99	101	PF00082	0.491
CLV_PCSK_PC7_1	189	195	PF00082	0.609
CLV_PCSK_SKI1_1	140	144	PF00082	0.552
CLV_PCSK_SKI1_1	152	156	PF00082	0.552
CLV_PCSK_SKI1_1	193	197	PF00082	0.639
CLV_PCSK_SKI1_1	77	81	PF00082	0.618
DEG_APCC_DBOX_1	103	111	PF00400	0.541
DEG_APCC_KENBOX_2	261	265	PF00400	0.613
DEG_COP1_1	67	75	PF00400	0.494
DEG_SPOP_SBC_1	268	272	PF00917	0.636
DOC_CYCLIN_RxL_1	74	84	PF00134	0.592
DOC_MAPK_gen_1	30	38	PF00069	0.559
DOC_PP1_RVXF_1	138	144	PF00149	0.529
DOC_PP1_RVXF_1	97	104	PF00149	0.539
DOC_USP7_MATH_1	135	139	PF00917	0.569
DOC_USP7_MATH_1	150	154	PF00917	0.504
DOC_USP7_MATH_1	268	272	PF00917	0.663
DOC_USP7_MATH_1	276	280	PF00917	0.578
DOC_USP7_MATH_1	37	41	PF00917	0.562
DOC_WW_Pin1_4	289	294	PF00397	0.608
DOC_WW_Pin1_4	50	55	PF00397	0.580
LIG_14-3-3_CanoR_1	140	148	PF00244	0.541
LIG_14-3-3_CanoR_1	17	25	PF00244	0.644
LIG_14-3-3_CanoR_1	66	73	PF00244	0.523
LIG_14-3-3_CanoR_1	77	87	PF00244	0.645
LIG_14-3-3_CanoR_1	99	104	PF00244	0.545
LIG_EH_1	31	35	PF12763	0.558
LIG_FHA_1	67	73	PF00498	0.565
LIG_FHA_2	179	185	PF00498	0.605
LIG_NRBOX	106	112	PF00104	0.424
LIG_PDZ_Class_3	293	298	PF00595	0.582
LIG_Rb_LxCxE_1	117	138	PF01857	0.470
LIG_SH2_CRK	167	171	PF00017	0.616
LIG_SH2_STAT5	228	231	PF00017	0.543
LIG_SH3_1	167	173	PF00018	0.611
LIG_SH3_3	167	173	PF00018	0.563
LIG_SH3_3	284	290	PF00018	0.605
LIG_SH3_3	84	90	PF00018	0.595
LIG_SUMO_SIM_par_1	34	41	PF11976	0.534
MOD_CDK_SPK_2	289	294	PF00069	0.505
MOD_CK1_1	102	108	PF00069	0.508
MOD_CK1_1	267	273	PF00069	0.665
MOD_CK1_1	71	77	PF00069	0.640
MOD_CK1_1	81	87	PF00069	0.565
MOD_CK2_1	178	184	PF00069	0.704
MOD_Cter_Amidation	190	193	PF01082	0.748
MOD_Cter_Amidation	203	206	PF01082	0.539
MOD_GlcNHglycan	152	155	PF01048	0.578
MOD_GlcNHglycan	202	205	PF01048	0.676
MOD_GlcNHglycan	221	224	PF01048	0.641
MOD_GlcNHglycan	256	259	PF01048	0.665
MOD_GlcNHglycan	266	269	PF01048	0.642
MOD_GlcNHglycan	278	281	PF01048	0.625
MOD_GlcNHglycan	56	59	PF01048	0.663
MOD_GlcNHglycan	83	86	PF01048	0.625
MOD_GSK3_1	105	112	PF00069	0.559
MOD_GSK3_1	262	269	PF00069	0.684
MOD_GSK3_1	50	57	PF00069	0.652
MOD_GSK3_1	64	71	PF00069	0.653
MOD_GSK3_1	95	102	PF00069	0.569
MOD_NEK2_1	254	259	PF00069	0.547
MOD_NEK2_1	266	271	PF00069	0.660
MOD_NEK2_1	281	286	PF00069	0.568
MOD_NEK2_1	6	11	PF00069	0.679
MOD_NEK2_1	79	84	PF00069	0.597
MOD_OFUCOSY	64	70	PF10250	0.568
MOD_PIKK_1	105	111	PF00454	0.565
MOD_PIKK_1	141	147	PF00454	0.466
MOD_PIKK_1	214	220	PF00454	0.605
MOD_PIKK_1	25	31	PF00454	0.551
MOD_PK_1	68	74	PF00069	0.554
MOD_PKA_1	99	105	PF00069	0.520
MOD_PKA_2	229	235	PF00069	0.469
MOD_PKA_2	88	94	PF00069	0.642
MOD_PKA_2	99	105	PF00069	0.438
MOD_PKB_1	192	200	PF00069	0.576
MOD_Plk_1	262	268	PF00069	0.699
MOD_ProDKin_1	289	295	PF00069	0.609
MOD_ProDKin_1	50	56	PF00069	0.583
TRG_ER_diArg_1	119	122	PF00400	0.544
TRG_ER_diArg_1	192	194	PF00400	0.777
TRG_ER_diArg_1	99	101	PF00400	0.582
TRG_Pf-PMV_PEXEL_1	4	8	PF00026	0.500

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P756	Leptomonas seymouri	35%	96%
A0A3S7WU02	Leishmania donovani	87%	100%
A4H8L3	Leishmania braziliensis	68%	100%
E9AGN6	Leishmania infantum	88%	100%
E9AQP8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%