Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QEQ8_LEIMA

TriTrypDb:

LmjF.16.1090 , LMJLV39_160017000 , LMJSD75_160016600

Length:

2147

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QEQ8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0006508	proteolysis	4	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0019538	protein metabolic process	3	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044238	primary metabolic process	2	1
GO:0071704	organic substance metabolic process	2	1
GO:1901564	organonitrogen compound metabolic process	3	1

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Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	1
GO:0008233	peptidase activity	3	1
GO:0008236	serine-type peptidase activity	4	1
GO:0016787	hydrolase activity	2	1
GO:0017171	serine hydrolase activity	3	1
GO:0140096	catalytic activity, acting on a protein	2	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1044	1048	PF00656	0.616
CLV_C14_Caspase3-7	1592	1596	PF00656	0.646
CLV_C14_Caspase3-7	1620	1624	PF00656	0.604
CLV_C14_Caspase3-7	1887	1891	PF00656	0.574
CLV_C14_Caspase3-7	256	260	PF00656	0.505
CLV_C14_Caspase3-7	829	833	PF00656	0.501
CLV_C14_Caspase3-7	938	942	PF00656	0.675
CLV_NRD_NRD_1	1009	1011	PF00675	0.721
CLV_NRD_NRD_1	1161	1163	PF00675	0.508
CLV_NRD_NRD_1	1190	1192	PF00675	0.643

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WU82	Leishmania donovani	86%	100%
A4H8N5	Leishmania braziliensis	54%	92%
A4HX06	Leishmania infantum	86%	100%
E9AQR8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	100%

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