Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QEQ5_LEIMA

TriTrypDb:

LmjF.16.1120 , LMJLV39_160017400 , LMJSD75_160017000

Length:

270

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QEQ5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QEQ5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	128	132	PF00656	0.667
CLV_C14_Caspase3-7	191	195	PF00656	0.795
CLV_C14_Caspase3-7	76	80	PF00656	0.634
CLV_NRD_NRD_1	11	13	PF00675	0.672
CLV_NRD_NRD_1	115	117	PF00675	0.624
CLV_NRD_NRD_1	16	18	PF00675	0.610
CLV_NRD_NRD_1	178	180	PF00675	0.477
CLV_NRD_NRD_1	182	184	PF00675	0.472
CLV_NRD_NRD_1	98	100	PF00675	0.684
CLV_PCSK_FUR_1	14	18	PF00082	0.660
CLV_PCSK_FUR_1	179	183	PF00082	0.650
CLV_PCSK_FUR_1	96	100	PF00082	0.665
CLV_PCSK_KEX2_1	11	13	PF00082	0.672
CLV_PCSK_KEX2_1	115	117	PF00082	0.603
CLV_PCSK_KEX2_1	16	18	PF00082	0.610
CLV_PCSK_KEX2_1	178	180	PF00082	0.477
CLV_PCSK_KEX2_1	181	183	PF00082	0.494
CLV_PCSK_KEX2_1	232	234	PF00082	0.649
CLV_PCSK_KEX2_1	96	98	PF00082	0.662
CLV_PCSK_PC1ET2_1	181	183	PF00082	0.674
CLV_PCSK_PC1ET2_1	232	234	PF00082	0.649
CLV_PCSK_PC7_1	12	18	PF00082	0.663
CLV_PCSK_PC7_1	178	184	PF00082	0.649
CLV_PCSK_PC7_1	93	99	PF00082	0.658
CLV_PCSK_SKI1_1	178	182	PF00082	0.506
CLV_PCSK_SKI1_1	219	223	PF00082	0.522
DOC_CDC14_PxL_1	59	67	PF14671	0.618
DOC_CYCLIN_yCln2_LP_2	245	251	PF00134	0.728
DOC_CYCLIN_yCln2_LP_2	60	66	PF00134	0.621
DOC_MAPK_MEF2A_6	53	62	PF00069	0.638
DOC_PP2B_LxvP_1	221	224	PF13499	0.432
DOC_PP2B_LxvP_1	245	248	PF13499	0.732
DOC_PP2B_LxvP_1	60	63	PF13499	0.756
DOC_PP2B_LxvP_1	64	67	PF13499	0.695
DOC_USP7_MATH_1	200	204	PF00917	0.653
DOC_USP7_MATH_2	248	254	PF00917	0.705
DOC_WW_Pin1_4	48	53	PF00397	0.696
LIG_14-3-3_CanoR_1	31	39	PF00244	0.723
LIG_APCC_ABBA_1	71	76	PF00400	0.638
LIG_BIR_III_4	207	211	PF00653	0.700
LIG_BRCT_BRCA1_1	147	151	PF00533	0.607
LIG_eIF4E_1	171	177	PF01652	0.602
LIG_FHA_1	234	240	PF00498	0.672
LIG_FHA_1	31	37	PF00498	0.621
LIG_FHA_2	191	197	PF00498	0.793
LIG_LIR_Gen_1	148	159	PF02991	0.593
LIG_LIR_Nem_3	148	154	PF02991	0.594
LIG_LIR_Nem_3	240	245	PF02991	0.551
LIG_MYND_1	63	67	PF01753	0.624
LIG_Pex14_1	242	246	PF04695	0.730
LIG_Pex14_2	151	155	PF04695	0.580
LIG_SH2_SRC	246	249	PF00017	0.653
LIG_SH2_STAT5	156	159	PF00017	0.599
LIG_SH2_STAT5	246	249	PF00017	0.734
LIG_SH3_3	161	167	PF00018	0.653
LIG_SH3_3	52	58	PF00018	0.712
LIG_SUMO_SIM_anti_2	38	43	PF11976	0.594
LIG_TYR_ITIM	154	159	PF00017	0.589
MOD_CDK_SPK_2	48	53	PF00069	0.626
MOD_CK1_1	118	124	PF00069	0.818
MOD_CK1_1	203	209	PF00069	0.578
MOD_CK1_1	237	243	PF00069	0.559
MOD_CK1_1	51	57	PF00069	0.625
MOD_CK1_1	89	95	PF00069	0.636
MOD_CK2_1	122	128	PF00069	0.821
MOD_CK2_1	190	196	PF00069	0.656
MOD_Cter_Amidation	9	12	PF01082	0.672
MOD_GlcNHglycan	109	112	PF01048	0.811
MOD_GlcNHglycan	117	120	PF01048	0.677
MOD_GlcNHglycan	124	127	PF01048	0.555
MOD_GlcNHglycan	133	136	PF01048	0.478
MOD_GlcNHglycan	186	189	PF01048	0.602
MOD_GlcNHglycan	190	193	PF01048	0.623
MOD_GlcNHglycan	198	201	PF01048	0.582
MOD_GlcNHglycan	252	255	PF01048	0.684
MOD_GSK3_1	103	110	PF00069	0.723
MOD_GSK3_1	117	124	PF00069	0.647
MOD_GSK3_1	184	191	PF00069	0.759
MOD_GSK3_1	196	203	PF00069	0.556
MOD_GSK3_1	233	240	PF00069	0.669
MOD_GSK3_1	44	51	PF00069	0.743
MOD_LATS_1	113	119	PF00433	0.812
MOD_NEK2_1	109	114	PF00069	0.811
MOD_NEK2_1	117	122	PF00069	0.678
MOD_NEK2_1	35	40	PF00069	0.738
MOD_NEK2_1	86	91	PF00069	0.630
MOD_OFUCOSY	157	162	PF10250	0.621
MOD_PKA_1	115	121	PF00069	0.814
MOD_PKA_2	10	16	PF00069	0.663
MOD_PKA_2	115	121	PF00069	0.814
MOD_PKA_2	30	36	PF00069	0.505
MOD_Plk_1	145	151	PF00069	0.445
MOD_Plk_1	234	240	PF00069	0.672
MOD_Plk_4	150	156	PF00069	0.590
MOD_Plk_4	172	178	PF00069	0.601
MOD_Plk_4	37	43	PF00069	0.594
MOD_Plk_4	44	50	PF00069	0.541
MOD_ProDKin_1	48	54	PF00069	0.696
TRG_DiLeu_BaLyEn_6	240	245	PF01217	0.722
TRG_DiLeu_BaLyEn_6	55	60	PF01217	0.537
TRG_ENDOCYTIC_2	156	159	PF00928	0.599
TRG_ENDOCYTIC_2	171	174	PF00928	0.611
TRG_ER_diArg_1	11	14	PF00400	0.669
TRG_ER_diArg_1	114	116	PF00400	0.604
TRG_ER_diArg_1	16	18	PF00400	0.610
TRG_ER_diArg_1	177	179	PF00400	0.623
TRG_ER_diArg_1	182	184	PF00400	0.575
TRG_ER_diArg_1	95	98	PF00400	0.658
TRG_NLS_MonoExtN_4	178	185	PF00514	0.658

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9AQS2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%