LeishMANIAdb
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Putative 60S ribosomal protein L39

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative 60S ribosomal protein L39
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania major
UniProt:
Q4QEQ0_LEIMA
TriTrypDb:
Length:
51

Annotations

Annotations by Jardim et al.

Ribosomal Protein, 60S ribosomal L39

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 2
GO:0015934 large ribosomal subunit 4 2
GO:0022625 cytosolic large ribosomal subunit 5 2
GO:0032991 protein-containing complex 1 8
GO:0044391 ribosomal subunit 3 2
GO:0110165 cellular anatomical entity 1 8
GO:1990904 ribonucleoprotein complex 2 8
GO:0005840 ribosome 5 6
GO:0043226 organelle 2 6
GO:0043228 non-membrane-bounded organelle 3 6
GO:0043229 intracellular organelle 3 6
GO:0043232 intracellular non-membrane-bounded organelle 4 6

Expansion

Sequence features

Q4QEQ0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QEQ0

PDB structure(s): 6az3_l

Function

Biological processes
Term Name Level Count
GO:0006412 translation 4 8
GO:0006518 peptide metabolic process 4 8
GO:0006807 nitrogen compound metabolic process 2 8
GO:0008152 metabolic process 1 8
GO:0009058 biosynthetic process 2 8
GO:0009059 macromolecule biosynthetic process 4 8
GO:0009987 cellular process 1 8
GO:0019538 protein metabolic process 3 8
GO:0034641 cellular nitrogen compound metabolic process 3 8
GO:0034645 obsolete cellular macromolecule biosynthetic process 4 8
GO:0043043 peptide biosynthetic process 5 8
GO:0043170 macromolecule metabolic process 3 8
GO:0043603 amide metabolic process 3 8
GO:0043604 amide biosynthetic process 4 8
GO:0044237 cellular metabolic process 2 8
GO:0044238 primary metabolic process 2 8
GO:0044249 cellular biosynthetic process 3 8
GO:0044260 obsolete cellular macromolecule metabolic process 3 8
GO:0044271 cellular nitrogen compound biosynthetic process 4 8
GO:0071704 organic substance metabolic process 2 8
GO:1901564 organonitrogen compound metabolic process 3 8
GO:1901566 organonitrogen compound biosynthetic process 4 8
GO:1901576 organic substance biosynthetic process 3 8
Molecular functions
Term Name Level Count
GO:0003735 structural constituent of ribosome 2 8
GO:0005198 structural molecule activity 1 8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 41 43 PF00675 0.256
CLV_NRD_NRD_1 45 47 PF00675 0.256
CLV_PCSK_KEX2_1 40 42 PF00082 0.256
CLV_PCSK_KEX2_1 45 47 PF00082 0.256
CLV_PCSK_PC1ET2_1 40 42 PF00082 0.256
CLV_PCSK_PC7_1 41 47 PF00082 0.256
CLV_PCSK_SKI1_1 12 16 PF00082 0.258
DOC_PP1_RVXF_1 32 38 PF00149 0.256
DOC_USP7_UBL2_3 11 15 PF12436 0.256
DOC_USP7_UBL2_3 36 40 PF12436 0.256
LIG_SH2_STAP1 13 17 PF00017 0.295
MOD_PKA_2 44 50 PF00069 0.256
TRG_ER_diArg_1 27 30 PF00400 0.256
TRG_ER_diArg_1 44 46 PF00400 0.256

Homologs

Protein Taxonomy Sequence identity Coverage
A0A1D8PDT4 Candida albicans (strain SC5314 / ATCC MYA-2876) 59% 100%
A0A3Q8IAG7 Leishmania donovani 100% 100%
A2BN55 Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5) 51% 100%
A3DNH3 Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1) 45% 100%
A4H8P4 Leishmania braziliensis 100% 100%
A4HX14 Leishmania infantum 100% 100%
A4YH79 Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) 43% 100%
B6YWY4 Thermococcus onnurineus (strain NA1) 49% 100%
C3MR76 Sulfolobus islandicus (strain L.S.2.15 / Lassen #1) 47% 100%
C3MXG5 Sulfolobus islandicus (strain M.14.25 / Kamchatka #1) 47% 100%
C3MZB1 Sulfolobus islandicus (strain M.16.27) 47% 100%
C3N7D1 Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1) 47% 100%
C3NGA3 Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2) 47% 100%
C4KII9 Sulfolobus islandicus (strain M.16.4 / Kamchatka #3) 47% 100%
C5A7H4 Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) 51% 100%
C6A264 Thermococcus sibiricus (strain DSM 12597 / MM 739) 45% 100%
C9ZVY8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 90% 100%
E9ALI7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 100% 100%
O16130 Drosophila melanogaster 61% 100%
O27650 Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) 47% 100%
O28212 Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) 47% 100%
P04650 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 56% 100%
P05767 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 60% 100%
P0DJ61 Tetrahymena thermophila (strain SB210) 49% 98%
P22452 Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) 48% 100%
P48536 Kluyveromyces marxianus 57% 100%
P51424 Arabidopsis thaliana 61% 100%
P51425 Zea mays 63% 100%
P51426 Oryza sativa subsp. japonica 63% 100%
P52814 Caenorhabditis elegans 57% 100%
P59472 Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) 47% 100%
P59473 Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) 57% 100%
P62891 Homo sapiens 57% 100%
P62892 Mus musculus 57% 100%
P62893 Rattus norvegicus 57% 100%
Q3T051 Bos taurus 57% 100%
Q59GN2 Homo sapiens 55% 100%
Q5JGT6 Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) 49% 100%
Q5SMI4 Oryza sativa subsp. japonica 63% 100%
Q6BHV8 Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) 60% 100%
Q6CW22 Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) 57% 100%
Q6F482 Plutella xylostella 59% 100%
Q6KAJ8 Oryza sativa subsp. japonica 63% 100%
Q6L2L2 Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828) 43% 100%
Q758D8 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) 55% 100%
Q8L8W6 Arabidopsis thaliana 61% 100%
Q8TUY3 Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) 53% 100%
Q8U3S6 Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) 51% 100%
Q90YS9 Ictalurus punctatus 56% 100%
Q962S4 Spodoptera frugiperda 59% 100%
Q96EH5 Homo sapiens 50% 100%
Q96W55 Candida albicans 59% 100%
Q980F9 Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) 47% 100%
Q98TF5 Gallus gallus 57% 100%
Q9UYI8 Pyrococcus abyssi (strain GE5 / Orsay) 55% 100%
V5BCD6 Trypanosoma cruzi 92% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS