LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Sm domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Sm domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QEP2_LEIMA
TriTrypDb:
LmjF.16.1250 , LMJLV39_160018800 * , LMJSD75_160018400
Length:
150

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
Term Name Level Count
GO:0032991 protein-containing complex 1 1
GO:1990904 ribonucleoprotein complex 2 1

Expansion

Sequence features

Q4QEP2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QEP2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 128 132 PF00656 0.524
CLV_NRD_NRD_1 59 61 PF00675 0.522
CLV_NRD_NRD_1 93 95 PF00675 0.627
CLV_PCSK_FUR_1 57 61 PF00082 0.494
CLV_PCSK_KEX2_1 57 59 PF00082 0.467
DEG_SPOP_SBC_1 76 80 PF00917 0.743
DOC_CYCLIN_RxL_1 116 129 PF00134 0.486
DOC_MAPK_gen_1 94 102 PF00069 0.581
DOC_MAPK_RevD_3 46 60 PF00069 0.468
DOC_PP1_RVXF_1 119 126 PF00149 0.419
DOC_USP7_MATH_1 76 80 PF00917 0.735
DOC_USP7_MATH_1 85 89 PF00917 0.664
DOC_WW_Pin1_4 80 85 PF00397 0.683
LIG_14-3-3_CanoR_1 94 102 PF00244 0.513
LIG_BIR_II_1 1 5 PF00653 0.627
LIG_Clathr_ClatBox_1 21 25 PF01394 0.373
LIG_Clathr_ClatBox_1 36 40 PF01394 0.476
LIG_FHA_1 28 34 PF00498 0.411
LIG_FHA_1 41 47 PF00498 0.415
LIG_FHA_1 68 74 PF00498 0.610
LIG_FHA_1 97 103 PF00498 0.495
LIG_LIR_Nem_3 134 139 PF02991 0.540
LIG_SH2_STAT5 119 122 PF00017 0.508
LIG_TYR_ITSM 132 139 PF00017 0.551
MOD_CK1_1 4 10 PF00069 0.555
MOD_CK1_1 78 84 PF00069 0.738
MOD_CK2_1 132 138 PF00069 0.564
MOD_GSK3_1 72 79 PF00069 0.733
MOD_GSK3_1 85 92 PF00069 0.602
MOD_N-GLC_1 27 32 PF02516 0.470
MOD_NEK2_1 1 6 PF00069 0.625
MOD_PKA_2 93 99 PF00069 0.635
MOD_PKB_1 58 66 PF00069 0.524
MOD_Plk_1 96 102 PF00069 0.565
MOD_Plk_4 109 115 PF00069 0.404
MOD_Plk_4 27 33 PF00069 0.499
MOD_ProDKin_1 80 86 PF00069 0.687
TRG_DiLeu_BaLyEn_6 32 37 PF01217 0.460
TRG_ENDOCYTIC_2 122 125 PF00928 0.420
TRG_ENDOCYTIC_2 136 139 PF00928 0.530
TRG_ER_diArg_1 56 59 PF00400 0.451
TRG_Pf-PMV_PEXEL_1 35 40 PF00026 0.422

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I4W6 Leptomonas seymouri 64% 100%
A0A1X0NYY2 Trypanosomatidae 42% 97%
A0A3R7LUA9 Trypanosoma rangeli 45% 100%
A0A3S7WU38 Leishmania donovani 93% 100%
A4H8Q3 Leishmania braziliensis 79% 100%
A4HX22 Leishmania infantum 93% 100%
C9ZVX7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 40% 100%
E9AQT6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS