Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Present in the outer mitochondrial membrane proteome 41

Species:

Leishmania major

UniProt:

Q4QEN7_LEIMA

TriTrypDb:

LmjF.16.1300 , LMJLV39_160019300 , LMJSD75_160018900

Length:

997

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Show entries

Cellular components
Term	Name	Level	Count
GO:0005741	mitochondrial outer membrane	5	2
GO:0016020	membrane	2	2
GO:0019867	outer membrane	3	2
GO:0031090	organelle membrane	3	2
GO:0031966	mitochondrial membrane	4	2
GO:0031968	organelle outer membrane	4	2
GO:0098588	bounding membrane of organelle	4	2
GO:0110165	cellular anatomical entity	1	2

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Expansion

Sequence features

Q4QEN7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QEN7

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	741	745	PF00656	0.422
CLV_C14_Caspase3-7	824	828	PF00656	0.669
CLV_NRD_NRD_1	289	291	PF00675	0.735
CLV_NRD_NRD_1	402	404	PF00675	0.459
CLV_NRD_NRD_1	456	458	PF00675	0.614
CLV_NRD_NRD_1	682	684	PF00675	0.499
CLV_NRD_NRD_1	69	71	PF00675	0.684
CLV_NRD_NRD_1	712	714	PF00675	0.435
CLV_NRD_NRD_1	796	798	PF00675	0.566
CLV_NRD_NRD_1	908	910	PF00675	0.811

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2G9	Leptomonas seymouri	42%	99%
A0A3Q8IAI0	Leishmania donovani	92%	100%
A4H8Q8	Leishmania braziliensis	70%	98%
A4HX27	Leishmania infantum	92%	100%
E9AQU1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%

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