ADP-ribosylation factor-like protein 6

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ADP-ribosylation factor-like, putative

Species:

Leishmania major

UniProt:

Q4QEM9_LEIMA

TriTrypDb:

LmjF.16.1380 , LMJLV39_160020100 , LMJSD75_160019700

Length:

182

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 6
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 14

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	2
GO:0005737	cytoplasm	2	2
GO:0005815	microtubule organizing center	2	2
GO:0005930	axoneme	2	2
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	2
GO:0036064	ciliary basal body	3	2
GO:0097014	ciliary plasm	5	2
GO:0099568	cytoplasmic region	3	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4QEM9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QEM9

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	2
GO:0006886	intracellular protein transport	4	2
GO:0006996	organelle organization	4	2
GO:0008104	protein localization	4	2
GO:0009987	cellular process	1	2
GO:0015031	protein transport	4	2
GO:0016043	cellular component organization	3	2
GO:0016192	vesicle-mediated transport	4	2
GO:0022607	cellular component assembly	4	2
GO:0030030	cell projection organization	4	2
GO:0030031	cell projection assembly	5	2
GO:0033036	macromolecule localization	2	2
GO:0033365	protein localization to organelle	5	2
GO:0044782	cilium organization	5	2
GO:0045184	establishment of protein localization	3	2
GO:0046907	intracellular transport	3	2
GO:0051179	localization	1	2
GO:0051234	establishment of localization	2	2
GO:0051641	cellular localization	2	2
GO:0051649	establishment of localization in cell	3	2
GO:0060271	cilium assembly	6	2
GO:0061512	protein localization to cilium	6	2
GO:0070727	cellular macromolecule localization	3	2
GO:0070925	organelle assembly	5	2
GO:0071702	organic substance transport	4	2
GO:0071705	nitrogen compound transport	4	2
GO:0071840	cellular component organization or biogenesis	2	2
GO:0120031	plasma membrane bounded cell projection assembly	6	2
GO:0120036	plasma membrane bounded cell projection organization	5	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	10
GO:0003824	catalytic activity	1	10
GO:0003924	GTPase activity	7	10
GO:0005488	binding	1	10
GO:0005525	GTP binding	5	10
GO:0016462	pyrophosphatase activity	5	10
GO:0016787	hydrolase activity	2	10
GO:0016817	hydrolase activity, acting on acid anhydrides	3	10
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	10
GO:0017076	purine nucleotide binding	4	10
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	10
GO:0019001	guanyl nucleotide binding	5	10
GO:0032553	ribonucleotide binding	3	10
GO:0032555	purine ribonucleotide binding	4	10
GO:0032561	guanyl ribonucleotide binding	5	10
GO:0035639	purine ribonucleoside triphosphate binding	4	10
GO:0036094	small molecule binding	2	10
GO:0043167	ion binding	2	10
GO:0043168	anion binding	3	10
GO:0097159	organic cyclic compound binding	2	10
GO:0097367	carbohydrate derivative binding	2	10
GO:1901265	nucleoside phosphate binding	3	10
GO:1901363	heterocyclic compound binding	2	10

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	75	79	PF00656	0.308
CLV_C14_Caspase3-7	85	89	PF00656	0.423
CLV_NRD_NRD_1	174	176	PF00675	0.369
CLV_PCSK_KEX2_1	174	176	PF00082	0.349
DOC_MAPK_DCC_7	109	118	PF00069	0.349
DOC_MAPK_gen_1	49	55	PF00069	0.446
DOC_MAPK_gen_1	5	12	PF00069	0.401
DOC_MAPK_MEF2A_6	109	118	PF00069	0.357
DOC_MAPK_MEF2A_6	5	12	PF00069	0.343
DOC_PP4_FxxP_1	26	29	PF00568	0.349
DOC_WW_Pin1_4	126	131	PF00397	0.401
LIG_CtBP_PxDLS_1	130	134	PF00389	0.401
LIG_FHA_1	132	138	PF00498	0.388
LIG_FHA_1	19	25	PF00498	0.314
LIG_FHA_2	127	133	PF00498	0.308
LIG_FHA_2	54	60	PF00498	0.304
LIG_LIR_Gen_1	112	122	PF02991	0.284
LIG_LIR_Gen_1	71	82	PF02991	0.335
LIG_LIR_Nem_3	112	118	PF02991	0.371
LIG_LIR_Nem_3	71	77	PF02991	0.335
LIG_Pex14_1	70	74	PF04695	0.284
LIG_Pex14_2	66	70	PF04695	0.284
LIG_REV1ctd_RIR_1	115	125	PF16727	0.343
LIG_SH2_GRB2like	74	77	PF00017	0.284
LIG_SH2_NCK_1	74	78	PF00017	0.284
LIG_SH2_STAT5	54	57	PF00017	0.305
LIG_SH3_4	28	35	PF00018	0.401
LIG_UBA3_1	11	20	PF00899	0.368
LIG_UBA3_1	172	181	PF00899	0.491
LIG_UBA3_1	23	28	PF00899	0.230
LIG_WRC_WIRS_1	45	50	PF05994	0.343
MOD_CK1_1	18	24	PF00069	0.290
MOD_CK1_1	72	78	PF00069	0.437
MOD_CK2_1	126	132	PF00069	0.308
MOD_GlcNHglycan	16	20	PF01048	0.293
MOD_GlcNHglycan	59	63	PF01048	0.439
MOD_GSK3_1	15	22	PF00069	0.303
MOD_NEK2_1	131	136	PF00069	0.324
MOD_NEK2_1	15	20	PF00069	0.376
MOD_NEK2_1	176	181	PF00069	0.556
MOD_NEK2_1	58	63	PF00069	0.359
MOD_NEK2_1	69	74	PF00069	0.245
MOD_NMyristoyl	1	7	PF02799	0.284
MOD_PIKK_1	131	137	PF00454	0.401
MOD_Plk_1	131	137	PF00069	0.327
MOD_Plk_4	138	144	PF00069	0.357
MOD_Plk_4	19	25	PF00069	0.335
MOD_Plk_4	69	75	PF00069	0.284
MOD_ProDKin_1	126	132	PF00069	0.401
MOD_SUMO_for_1	27	30	PF00179	0.401
MOD_SUMO_for_1	95	98	PF00179	0.308
TRG_ENDOCYTIC_2	74	77	PF00928	0.284
TRG_ER_diArg_1	173	175	PF00400	0.410
TRG_NES_CRM1_1	163	177	PF08389	0.401
TRG_Pf-PMV_PEXEL_1	174	178	PF00026	0.388
TRG_Pf-PMV_PEXEL_1	67	71	PF00026	0.332

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3Q3	Leptomonas seymouri	32%	96%
A0A0N0P4P7	Leptomonas seymouri	80%	100%
A0A0N0P633	Leptomonas seymouri	36%	99%
A0A0N0P8D4	Leptomonas seymouri	34%	100%
A0A0N0P8Z3	Leptomonas seymouri	32%	100%
A0A0N1HS40	Leptomonas seymouri	27%	100%
A0A0N1HTN6	Leptomonas seymouri	33%	96%
A0A0N1I3A9	Leptomonas seymouri	34%	100%
A0A0N1I556	Leptomonas seymouri	36%	100%
A0A0N1I6N0	Leptomonas seymouri	31%	100%
A0A0N1IKF2	Leptomonas seymouri	26%	93%
A0A0N1PD39	Leptomonas seymouri	31%	100%
A0A0S4IQT8	Bodo saltans	34%	97%
A0A0S4IS60	Bodo saltans	32%	100%
A0A0S4J2X3	Bodo saltans	34%	100%
A0A0S4J3L7	Bodo saltans	33%	100%
A0A0S4J5U8	Bodo saltans	29%	96%
A0A0S4J8H6	Bodo saltans	36%	100%
A0A0S4JK65	Bodo saltans	29%	100%
A0A0S4JQ13	Bodo saltans	29%	93%
A0A0S4KJ70	Bodo saltans	36%	85%
A0A0S4KKS9	Bodo saltans	36%	100%
A0A1X0NKM5	Trypanosomatidae	28%	98%
A0A1X0NKZ8	Trypanosomatidae	29%	94%
A0A1X0NLB1	Trypanosomatidae	33%	96%
A0A1X0NLP5	Trypanosomatidae	34%	99%
A0A1X0NT19	Trypanosomatidae	35%	96%
A0A1X0NZX3	Trypanosomatidae	36%	100%
A0A1X0P0A2	Trypanosomatidae	32%	100%
A0A1X0P0D4	Trypanosomatidae	60%	94%
A0A1X0P1Y5	Trypanosomatidae	31%	99%
A0A1X0P2L5	Trypanosomatidae	27%	94%
A0A1X0P5P0	Trypanosomatidae	35%	100%
A0A1X0P676	Trypanosomatidae	27%	95%
A0A221LG87	Leishmania donovani	26%	93%
A0A3Q8IDS2	Leishmania donovani	97%	100%
A0A3Q8IFX9	Leishmania donovani	34%	100%
A0A3R7KSW8	Trypanosoma rangeli	33%	100%
A0A3R7L2X6	Trypanosoma rangeli	36%	100%
A0A3R7MW79	Trypanosoma rangeli	33%	96%
A0A3R7NC73	Trypanosoma rangeli	38%	96%
A0A3R7NMH3	Trypanosoma rangeli	28%	96%
A0A3R7RGT1	Trypanosoma rangeli	35%	99%
A0A3S5H598	Leishmania donovani	30%	99%
A0A3S5H5A9	Leishmania donovani	32%	96%
A0A3S5IQP0	Trypanosoma rangeli	31%	98%
A0A3S5ISB1	Trypanosoma rangeli	27%	99%
A0A3S7WU76	Leishmania donovani	32%	97%
A0A3S7X4X3	Leishmania donovani	36%	100%
A0A3S7X8N3	Leishmania donovani	29%	98%
A0A3S7XC57	Leishmania donovani	36%	100%
A0A422MYB1	Trypanosoma rangeli	35%	100%
A0A422MZM4	Trypanosoma rangeli	58%	94%
A0A422NNC6	Trypanosoma rangeli	30%	95%
A0A422NRN0	Trypanosoma rangeli	36%	100%
A0A422NW53	Trypanosoma rangeli	32%	98%
A1CRG9	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	31%	96%
A1D4D1	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	31%	96%
A3LTA2	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	30%	96%
A4H3V3	Leishmania braziliensis	31%	99%
A4H3W8	Leishmania braziliensis	33%	96%
A4H449	Leishmania braziliensis	27%	93%
A4H8R6	Leishmania braziliensis	88%	100%
A4H8V3	Leishmania braziliensis	32%	97%
A4HH98	Leishmania braziliensis	34%	100%
A4HJL1	Leishmania braziliensis	37%	100%
A4HJR7	Leishmania braziliensis	36%	100%
A4HM52	Leishmania braziliensis	31%	98%
A4HQE3	Leishmania braziliensis	33%	100%
A4HS29	Leishmania infantum	30%	99%
A4HS43	Leishmania infantum	32%	96%
A4HSC6	Leishmania infantum	26%	93%
A4HX34	Leishmania infantum	97%	100%
A4HX72	Leishmania infantum	32%	97%
A4I4E4	Leishmania infantum	34%	100%
A4I5R5	Leishmania infantum	34%	100%
A4I784	Leishmania infantum	36%	100%
A4IAR4	Leishmania infantum	29%	98%
A4IE34	Leishmania infantum	36%	100%
A5DR82	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	33%	96%
A5E5G3	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	30%	96%
A6NH57	Homo sapiens	33%	100%
A8ISN6	Chlamydomonas reinhardtii	36%	100%
B5FYQ0	Taeniopygia guttata	34%	100%
C9ZL19	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
C9ZPY6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	94%
C9ZR33	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	99%
C9ZTU8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	96%
C9ZVV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	60%	96%
C9ZY21	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	94%
C9ZY41	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	96%
C9ZZD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
C9ZZD6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
D0A2E8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	98%
D0A2Q7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	67%
E9ADU4	Leishmania major	33%	100%
E9AEJ0	Leishmania major	29%	100%
E9AHL7	Leishmania infantum	36%	100%
E9AIU0	Leishmania braziliensis	34%	100%
E9AK16	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	99%
E9AK30	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9AKA7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	93%
E9ALY6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9AQU9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
E9ARC9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	97%
E9AU58	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	100%
E9B110	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9B229	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	100%
E9B278	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	100%
E9B5Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	98%
F4IZ82	Arabidopsis thaliana	35%	100%
O00909	Dictyostelium discoideum	36%	100%
O04266	Brassica campestris	31%	94%
O04267	Brassica campestris	31%	93%
O04834	Arabidopsis thaliana	29%	94%
O08697	Rattus norvegicus	32%	99%
O23778	Catharanthus roseus	38%	100%
O45379	Caenorhabditis elegans	36%	99%
O48649	Salix bakko	38%	100%
O48920	Vigna unguiculata	38%	100%
O88848	Mus musculus	47%	98%
P0C583	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	34%	96%
P0C950	Aspergillus niger	30%	96%
P0C951	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	31%	96%
P0CM16	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	34%	100%
P0CM17	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	34%	100%
P0CR30	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	32%	96%
P0CR31	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	32%	96%
P0CT16	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	32%	96%
P0CT17	Magnaporthe oryzae (strain Y34)	32%	96%
P0DH91	Arabidopsis thaliana	39%	100%
P11076	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	100%
P18085	Homo sapiens	35%	100%
P19146	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	100%
P20606	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	96%
P22274	Candida albicans (strain SC5314 / ATCC MYA-2876)	35%	100%
P25160	Drosophila melanogaster	35%	100%
P26990	Gallus gallus	34%	100%
P26991	Giardia intestinalis	35%	95%
P32939	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	88%
P34212	Caenorhabditis elegans	37%	100%
P34727	Ajellomyces capsulatus	37%	99%
P36397	Arabidopsis thaliana	39%	100%
P36404	Homo sapiens	32%	99%
P36405	Homo sapiens	33%	100%
P36536	Mus musculus	28%	92%
P36579	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	100%
P37996	Rattus norvegicus	34%	100%
P38116	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	99%
P39110	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	95%
P40616	Homo sapiens	37%	100%
P40617	Homo sapiens	34%	91%
P40940	Arabidopsis thaliana	36%	100%
P40945	Drosophila melanogaster	36%	100%
P40946	Drosophila melanogaster	34%	100%
P40994	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	99%
P49076	Zea mays	40%	100%
P49702	Gallus gallus	33%	100%
P49703	Homo sapiens	30%	91%
P51643	Xenopus laevis	35%	100%
P51644	Xenopus laevis	34%	100%
P51645	Xenopus laevis	34%	100%
P51646	Rattus norvegicus	37%	100%
P51821	Chlamydomonas reinhardtii	38%	100%
P51822	Daucus carota	38%	100%
P51823	Oryza sativa subsp. japonica	39%	100%
P51824	Solanum tuberosum	38%	92%
P52884	Solanum lycopersicum	31%	94%
P52885	Nicotiana tabacum	28%	92%
P56559	Homo sapiens	34%	95%
P61204	Homo sapiens	35%	100%
P61205	Mus musculus	35%	100%
P61206	Rattus norvegicus	35%	100%
P61207	Takifugu rubripes	35%	100%
P61208	Mus musculus	34%	95%
P61209	Drosophila melanogaster	35%	100%
P61210	Locusta migratoria	35%	100%
P61211	Mus musculus	37%	100%
P61212	Rattus norvegicus	37%	100%
P61213	Mus musculus	34%	91%
P61214	Rattus norvegicus	34%	91%
P61750	Mus musculus	34%	100%
P61751	Rattus norvegicus	34%	100%
P62330	Homo sapiens	34%	100%
P62331	Mus musculus	34%	100%
P62332	Rattus norvegicus	34%	100%
P78976	Hypocrea jecorina	31%	96%
P84077	Homo sapiens	35%	100%
P84078	Mus musculus	35%	100%
P84079	Rattus norvegicus	35%	100%
P84080	Bos taurus	35%	100%
P84081	Bos taurus	34%	100%
P84082	Rattus norvegicus	34%	100%
P84083	Rattus norvegicus	34%	100%
P84084	Mus musculus	34%	100%
P84085	Homo sapiens	34%	100%
P91924	Dugesia japonica	36%	99%
Q007T5	Sus scrofa	34%	100%
Q01474	Arabidopsis thaliana	31%	94%
Q01475	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	96%
Q02804	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	92%
Q06396	Oryza sativa subsp. japonica	39%	100%
Q06849	Drosophila melanogaster	31%	99%
Q09767	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	98%
Q0CUN7	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	31%	96%
Q0IIM2	Bos taurus	47%	98%
Q0UKC0	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	32%	98%
Q0VC18	Bos taurus	31%	91%
Q10943	Caenorhabditis elegans	35%	100%
Q13795	Homo sapiens	30%	91%
Q18510	Caenorhabditis elegans	42%	96%
Q19705	Caenorhabditis elegans	31%	99%
Q1MTE5	Danio rerio	34%	100%
Q1ZXA5	Dictyostelium discoideum	34%	98%
Q20758	Caenorhabditis elegans	33%	100%
Q23445	Caenorhabditis elegans	30%	94%
Q25761	Plasmodium falciparum (isolate NF54)	37%	100%
Q2HA55	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	32%	96%
Q2KI07	Bos taurus	29%	98%
Q2KJ96	Bos taurus	38%	100%
Q2TA37	Bos taurus	32%	99%
Q2TBW6	Bos taurus	33%	100%
Q2YDM1	Bos taurus	37%	100%
Q32LJ2	Bos taurus	29%	91%
Q3SXC5	Mus musculus	29%	95%
Q3SZF2	Bos taurus	34%	100%
Q3T0D7	Bos taurus	28%	92%
Q3T0M9	Bos taurus	34%	91%
Q3T0T7	Bos taurus	26%	92%
Q4P0I7	Ustilago maydis (strain 521 / FGSC 9021)	32%	96%
Q4Q0D7	Leishmania major	36%	100%
Q4Q5Y0	Leishmania major	37%	100%
Q4Q756	Leishmania major	34%	100%
Q4QEJ1	Leishmania major	33%	100%
Q4QJK0	Leishmania major	26%	93%
Q4R4S4	Macaca fascicularis	29%	98%
Q4R5P2	Macaca fascicularis	35%	100%
Q4WJS7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	31%	96%
Q52NJ3	Sus scrofa	28%	92%
Q52NJ4	Sus scrofa	33%	100%
Q54HK2	Dictyostelium discoideum	32%	96%
Q54I24	Dictyostelium discoideum	33%	84%
Q54JJ3	Dictyostelium discoideum	33%	96%
Q54R04	Dictyostelium discoideum	31%	98%
Q54UF1	Dictyostelium discoideum	33%	99%
Q54V41	Dictyostelium discoideum	33%	97%
Q54V47	Dictyostelium discoideum	34%	97%
Q54Y14	Dictyostelium discoideum	27%	94%
Q54YV7	Dictyostelium discoideum	25%	93%
Q559R0	Dictyostelium discoideum	30%	97%
Q55AD9	Dictyostelium discoideum	38%	99%
Q58DI9	Bos taurus	31%	100%
Q59S78	Candida albicans (strain SC5314 / ATCC MYA-2876)	31%	96%
Q5BGB9	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	31%	96%
Q5BK71	Rattus norvegicus	34%	100%
Q5E9I6	Bos taurus	35%	100%
Q5EA19	Bos taurus	29%	90%
Q5HZY2	Rattus norvegicus	26%	92%
Q5M9P8	Danio rerio	45%	98%
Q5PYH3	Sus scrofa	26%	92%
Q5R4G5	Pongo abelii	47%	98%
Q5R548	Pongo abelii	28%	92%
Q5R579	Pongo abelii	30%	91%
Q5R5P7	Pongo abelii	35%	100%
Q5R6E7	Pongo abelii	29%	98%
Q5RCF1	Pongo abelii	35%	100%
Q5RCQ6	Pongo abelii	28%	100%
Q5REU3	Pongo abelii	30%	91%
Q5RFN0	Pongo abelii	29%	89%
Q5VLR7	Leishmania donovani	36%	100%
Q5ZKQ8	Gallus gallus	30%	98%
Q60Z38	Caenorhabditis briggsae	44%	96%
Q61LA8	Caenorhabditis briggsae	35%	100%
Q627K4	Caenorhabditis briggsae	32%	99%
Q63055	Rattus norvegicus	29%	91%
Q66HA6	Rattus norvegicus	29%	98%
Q6BVA7	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	32%	96%
Q6CB54	Yarrowia lipolytica (strain CLIB 122 / E 150)	31%	96%
Q6CWR7	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	30%	96%
Q6FUZ9	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	33%	96%
Q6IMM3	Leishmania major	36%	100%
Q6NZW8	Danio rerio	29%	98%
Q6P068	Mus musculus	37%	100%
Q6P3A9	Mus musculus	33%	100%
Q6P8C8	Xenopus tropicalis	30%	98%
Q6T311	Homo sapiens	29%	97%
Q755D7	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	32%	96%
Q75A26	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	34%	100%
Q7KQL3	Plasmodium falciparum (isolate 3D7)	38%	100%
Q7RVM2	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	35%	98%
Q80ZU0	Mus musculus	37%	100%
Q877B9	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	31%	96%
Q8BGR6	Mus musculus	30%	89%
Q8BSL7	Mus musculus	34%	100%
Q8BXL7	Mus musculus	29%	91%
Q8MQT8	Giardia intestinalis	29%	95%
Q8N4G2	Homo sapiens	32%	95%
Q8N8L6	Homo sapiens	31%	75%
Q8QHI3	Xenopus laevis	33%	100%
Q8SS09	Encephalitozoon cuniculi (strain GB-M1)	30%	82%
Q8VEH3	Mus musculus	30%	98%
Q8VY57	Arabidopsis thaliana	33%	99%
Q8W4C8	Arabidopsis thaliana	30%	99%
Q93Y31	Arabidopsis thaliana	32%	99%
Q94231	Caenorhabditis elegans	37%	100%
Q94650	Plasmodium falciparum	38%	100%
Q96361	Brassica rapa subsp. pekinensis	36%	100%
Q969Q4	Homo sapiens	33%	93%
Q96BM9	Homo sapiens	30%	98%
Q96KC2	Homo sapiens	40%	100%
Q99PE9	Mus musculus	31%	91%
Q9CQC9	Mus musculus	26%	92%
Q9CQW2	Mus musculus	29%	98%
Q9D0J4	Mus musculus	32%	99%
Q9D4P0	Mus musculus	40%	100%
Q9H0F7	Homo sapiens	47%	98%
Q9LQC8	Arabidopsis thaliana	39%	100%
Q9N6B0	Leishmania donovani	34%	100%
Q9NR31	Homo sapiens	28%	92%
Q9NVJ2	Homo sapiens	29%	98%
Q9NXU5	Homo sapiens	29%	89%
Q9P4C8	Komagataella phaffii (strain GS115 / ATCC 20864)	29%	96%
Q9QVY3	Cricetulus griseus	26%	92%
Q9QXJ4	Mus musculus	33%	75%
Q9SHU5	Arabidopsis thaliana	34%	89%
Q9U0T6	Leishmania major	31%	96%
Q9VHV5	Drosophila melanogaster	29%	98%
Q9WUL7	Mus musculus	34%	100%
Q9XZX2	Leishmania major	30%	99%
Q9Y689	Homo sapiens	37%	100%
Q9Y6B6	Homo sapiens	26%	92%
Q9Y7Z2	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	99%
Q9ZPX1	Arabidopsis thaliana	36%	98%
V5B891	Trypanosoma cruzi	36%	96%
V5DJR8	Trypanosoma cruzi	31%	98%