SIT4 phosphatase-associated family protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QEL3_LEIMA

TriTrypDb:

LmjF.16.1520 , LMJLV39_160022100 , LMJSD75_160021800

Length:

1145

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0031298	replication fork protection complex	3	2
GO:0032991	protein-containing complex	1	2
GO:0140513	nuclear protein-containing complex	2	2

Expansion

Sequence features

Q4QEL3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QEL3

Function

Biological processes
Term	Name	Level	Count
GO:0000075	cell cycle checkpoint signaling	4	2
GO:0000076	DNA replication checkpoint signaling	6	2
GO:0006139	nucleobase-containing compound metabolic process	3	2
GO:0006259	DNA metabolic process	4	2
GO:0006275	regulation of DNA replication	6	2
GO:0006281	DNA repair	5	2
GO:0006725	cellular aromatic compound metabolic process	3	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0006950	response to stress	2	2
GO:0006974	DNA damage response	4	2
GO:0007165	signal transduction	2	2
GO:0008152	metabolic process	1	2
GO:0008156	negative regulation of DNA replication	7	2
GO:0009892	negative regulation of metabolic process	4	2
GO:0009987	cellular process	1	2
GO:0010564	regulation of cell cycle process	5	2
GO:0010605	negative regulation of macromolecule metabolic process	5	2
GO:0010948	negative regulation of cell cycle process	6	2
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	2
GO:0019222	regulation of metabolic process	3	2
GO:0031323	regulation of cellular metabolic process	4	2
GO:0031324	negative regulation of cellular metabolic process	5	2
GO:0031570	DNA integrity checkpoint signaling	5	2
GO:0033554	cellular response to stress	3	2
GO:0034641	cellular nitrogen compound metabolic process	3	2
GO:0035556	intracellular signal transduction	3	2
GO:0043111	replication fork arrest	6	2
GO:0043170	macromolecule metabolic process	3	2
GO:0044237	cellular metabolic process	2	2
GO:0044238	primary metabolic process	2	2
GO:0044260	obsolete cellular macromolecule metabolic process	3	2
GO:0045005	DNA-templated DNA replication maintenance of fidelity	5	2
GO:0045786	negative regulation of cell cycle	5	2
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	6	2
GO:0046483	heterocycle metabolic process	3	2
GO:0048478	obsolete replication fork protection	6	2
GO:0048519	negative regulation of biological process	3	2
GO:0048523	negative regulation of cellular process	4	2
GO:0050789	regulation of biological process	2	2
GO:0050794	regulation of cellular process	3	2
GO:0050896	response to stimulus	1	2
GO:0051052	regulation of DNA metabolic process	5	2
GO:0051053	negative regulation of DNA metabolic process	6	2
GO:0051171	regulation of nitrogen compound metabolic process	4	2
GO:0051172	negative regulation of nitrogen compound metabolic process	5	2
GO:0051716	cellular response to stimulus	2	2
GO:0051726	regulation of cell cycle	4	2
GO:0060255	regulation of macromolecule metabolic process	4	2
GO:0065007	biological regulation	1	2
GO:0071704	organic substance metabolic process	2	2
GO:0080090	regulation of primary metabolic process	4	2
GO:0090304	nucleic acid metabolic process	4	2
GO:0090329	regulation of DNA-templated DNA replication	7	2
GO:1901360	organic cyclic compound metabolic process	3	2
GO:1901987	regulation of cell cycle phase transition	6	2
GO:1901988	negative regulation of cell cycle phase transition	7	2
GO:2000104	negative regulation of DNA-templated DNA replication	8	2

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	2
GO:0003677	DNA binding	4	2
GO:0005488	binding	1	2
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1037	1041	PF00656	0.760
CLV_C14_Caspase3-7	1091	1095	PF00656	0.668
CLV_C14_Caspase3-7	1104	1108	PF00656	0.653
CLV_C14_Caspase3-7	728	732	PF00656	0.700
CLV_C14_Caspase3-7	75	79	PF00656	0.606
CLV_C14_Caspase3-7	797	801	PF00656	0.639
CLV_C14_Caspase3-7	997	1001	PF00656	0.645
CLV_NRD_NRD_1	1088	1090	PF00675	0.798
CLV_NRD_NRD_1	429	431	PF00675	0.683
CLV_NRD_NRD_1	442	444	PF00675	0.534
CLV_NRD_NRD_1	604	606	PF00675	0.417
CLV_NRD_NRD_1	775	777	PF00675	0.634
CLV_PCSK_KEX2_1	1002	1004	PF00082	0.792
CLV_PCSK_KEX2_1	1069	1071	PF00082	0.706
CLV_PCSK_KEX2_1	1086	1088	PF00082	0.725
CLV_PCSK_KEX2_1	176	178	PF00082	0.438
CLV_PCSK_KEX2_1	429	431	PF00082	0.693
CLV_PCSK_KEX2_1	444	446	PF00082	0.522
CLV_PCSK_KEX2_1	603	605	PF00082	0.415
CLV_PCSK_KEX2_1	7	9	PF00082	0.510
CLV_PCSK_KEX2_1	701	703	PF00082	0.592
CLV_PCSK_PC1ET2_1	1002	1004	PF00082	0.792
CLV_PCSK_PC1ET2_1	1069	1071	PF00082	0.738
CLV_PCSK_PC1ET2_1	1086	1088	PF00082	0.806
CLV_PCSK_PC1ET2_1	176	178	PF00082	0.438
CLV_PCSK_PC1ET2_1	444	446	PF00082	0.589
CLV_PCSK_PC1ET2_1	7	9	PF00082	0.510
CLV_PCSK_PC1ET2_1	701	703	PF00082	0.624
CLV_PCSK_SKI1_1	1028	1032	PF00082	0.795
CLV_PCSK_SKI1_1	1054	1058	PF00082	0.768
CLV_PCSK_SKI1_1	147	151	PF00082	0.568
CLV_PCSK_SKI1_1	333	337	PF00082	0.297
CLV_PCSK_SKI1_1	447	451	PF00082	0.578
CLV_PCSK_SKI1_1	486	490	PF00082	0.447
CLV_PCSK_SKI1_1	546	550	PF00082	0.515
CLV_PCSK_SKI1_1	553	557	PF00082	0.551
CLV_PCSK_SKI1_1	655	659	PF00082	0.426
CLV_PCSK_SKI1_1	8	12	PF00082	0.461
CLV_PCSK_SKI1_1	824	828	PF00082	0.683
CLV_PCSK_SKI1_1	898	902	PF00082	0.436
CLV_PCSK_SKI1_1	965	969	PF00082	0.503
CLV_Separin_Metazoa	483	487	PF03568	0.317
CLV_Separin_Metazoa	741	745	PF03568	0.690
DEG_APCC_DBOX_1	1002	1010	PF00400	0.606
DEG_APCC_DBOX_1	332	340	PF00400	0.292
DEG_APCC_DBOX_1	545	553	PF00400	0.474
DEG_APCC_DBOX_1	7	15	PF00400	0.488
DEG_APCC_DBOX_1	823	831	PF00400	0.713
DEG_SPOP_SBC_1	24	28	PF00917	0.507
DOC_AGCK_PIF_1	677	682	PF00069	0.468
DOC_CYCLIN_RxL_1	962	972	PF00134	0.517
DOC_CYCLIN_yCln2_LP_2	105	111	PF00134	0.485
DOC_MAPK_gen_1	176	184	PF00069	0.530
DOC_MAPK_gen_1	502	512	PF00069	0.492
DOC_MAPK_gen_1	603	612	PF00069	0.452
DOC_MAPK_gen_1	7	14	PF00069	0.568
DOC_MAPK_MEF2A_6	104	111	PF00069	0.534
DOC_MAPK_MEF2A_6	127	136	PF00069	0.403
DOC_MAPK_MEF2A_6	183	192	PF00069	0.409
DOC_MAPK_MEF2A_6	217	225	PF00069	0.399
DOC_MAPK_MEF2A_6	264	273	PF00069	0.763
DOC_MAPK_MEF2A_6	603	612	PF00069	0.503
DOC_MAPK_MEF2A_6	650	658	PF00069	0.413
DOC_MAPK_MEF2A_6	7	14	PF00069	0.568
DOC_MAPK_NFAT4_5	7	15	PF00069	0.572
DOC_MAPK_RevD_3	163	177	PF00069	0.403
DOC_PP1_RVXF_1	548	555	PF00149	0.296
DOC_PP1_RVXF_1	653	659	PF00149	0.466
DOC_PP2B_LxvP_1	105	108	PF13499	0.481
DOC_PP2B_LxvP_1	134	137	PF13499	0.455
DOC_PP2B_LxvP_1	697	700	PF13499	0.562
DOC_PP4_FxxP_1	922	925	PF00568	0.425
DOC_USP7_MATH_1	25	29	PF00917	0.400
DOC_USP7_MATH_1	299	303	PF00917	0.658
DOC_USP7_MATH_1	338	342	PF00917	0.485
DOC_USP7_MATH_1	398	402	PF00917	0.625
DOC_USP7_MATH_1	526	530	PF00917	0.387
DOC_USP7_MATH_1	642	646	PF00917	0.411
DOC_USP7_MATH_1	700	704	PF00917	0.651
DOC_USP7_UBL2_3	383	387	PF12436	0.630
DOC_USP7_UBL2_3	690	694	PF12436	0.516
DOC_USP7_UBL2_3	704	708	PF12436	0.729
DOC_WW_Pin1_4	1015	1020	PF00397	0.648
DOC_WW_Pin1_4	361	366	PF00397	0.720
DOC_WW_Pin1_4	454	459	PF00397	0.675
DOC_WW_Pin1_4	522	527	PF00397	0.597
DOC_WW_Pin1_4	844	849	PF00397	0.539
LIG_14-3-3_CanoR_1	138	145	PF00244	0.594
LIG_14-3-3_CanoR_1	23	31	PF00244	0.409
LIG_14-3-3_CanoR_1	367	373	PF00244	0.667
LIG_14-3-3_CanoR_1	486	491	PF00244	0.321
LIG_14-3-3_CanoR_1	934	939	PF00244	0.626
LIG_Actin_WH2_2	535	552	PF00022	0.375
LIG_APCC_ABBAyCdc20_2	277	283	PF00400	0.699
LIG_BIR_II_1	1	5	PF00653	0.497
LIG_BRCT_BRCA1_1	1017	1021	PF00533	0.579
LIG_BRCT_BRCA1_1	27	31	PF00533	0.524
LIG_BRCT_BRCA1_1	478	482	PF00533	0.499
LIG_BRCT_BRCA1_1	838	842	PF00533	0.537
LIG_BRCT_BRCA1_1	885	889	PF00533	0.538
LIG_Clathr_ClatBox_1	11	15	PF01394	0.567
LIG_deltaCOP1_diTrp_1	1071	1076	PF00928	0.576
LIG_deltaCOP1_diTrp_1	325	331	PF00928	0.452
LIG_deltaCOP1_diTrp_1	386	390	PF00928	0.684
LIG_deltaCOP1_diTrp_1	756	764	PF00928	0.685
LIG_EH1_1	218	226	PF00400	0.498
LIG_EH1_1	574	582	PF00400	0.322
LIG_EH1_1	873	881	PF00400	0.489
LIG_eIF4E_1	614	620	PF01652	0.464
LIG_eIF4E_1	693	699	PF01652	0.523
LIG_FHA_1	196	202	PF00498	0.403
LIG_FHA_1	206	212	PF00498	0.537
LIG_FHA_1	264	270	PF00498	0.746
LIG_FHA_1	47	53	PF00498	0.582
LIG_FHA_1	518	524	PF00498	0.625
LIG_FHA_1	554	560	PF00498	0.462
LIG_FHA_1	679	685	PF00498	0.457
LIG_FHA_1	89	95	PF00498	0.478
LIG_FHA_1	962	968	PF00498	0.600
LIG_FHA_2	1113	1119	PF00498	0.755
LIG_FHA_2	176	182	PF00498	0.535
LIG_FHA_2	244	250	PF00498	0.613
LIG_FHA_2	974	980	PF00498	0.636
LIG_GBD_Chelix_1	611	619	PF00786	0.382
LIG_IRF3_LxIS_1	14	20	PF10401	0.572
LIG_KLC1_Yacidic_2	974	979	PF13176	0.631
LIG_LIR_Apic_2	341	347	PF02991	0.549
LIG_LIR_Apic_2	921	925	PF02991	0.446
LIG_LIR_Gen_1	160	171	PF02991	0.399
LIG_LIR_Gen_1	270	280	PF02991	0.535
LIG_LIR_Gen_1	421	428	PF02991	0.690
LIG_LIR_Gen_1	475	485	PF02991	0.429
LIG_LIR_Gen_1	489	498	PF02991	0.435
LIG_LIR_Gen_1	529	539	PF02991	0.478
LIG_LIR_Gen_1	587	597	PF02991	0.438
LIG_LIR_Gen_1	681	688	PF02991	0.475
LIG_LIR_Gen_1	839	848	PF02991	0.539
LIG_LIR_Gen_1	852	863	PF02991	0.522
LIG_LIR_Gen_1	91	101	PF02991	0.463
LIG_LIR_Gen_1	972	983	PF02991	0.501
LIG_LIR_Gen_1	988	994	PF02991	0.601
LIG_LIR_LC3C_4	103	107	PF02991	0.493
LIG_LIR_LC3C_4	222	227	PF02991	0.451
LIG_LIR_Nem_3	159	165	PF02991	0.397
LIG_LIR_Nem_3	270	276	PF02991	0.536
LIG_LIR_Nem_3	385	391	PF02991	0.553
LIG_LIR_Nem_3	421	426	PF02991	0.755
LIG_LIR_Nem_3	475	480	PF02991	0.414
LIG_LIR_Nem_3	489	493	PF02991	0.394
LIG_LIR_Nem_3	529	535	PF02991	0.541
LIG_LIR_Nem_3	565	569	PF02991	0.649
LIG_LIR_Nem_3	587	593	PF02991	0.439
LIG_LIR_Nem_3	681	685	PF02991	0.470
LIG_LIR_Nem_3	787	793	PF02991	0.737
LIG_LIR_Nem_3	839	845	PF02991	0.498
LIG_LIR_Nem_3	852	858	PF02991	0.466
LIG_LIR_Nem_3	885	891	PF02991	0.489
LIG_LIR_Nem_3	953	957	PF02991	0.470
LIG_LIR_Nem_3	972	978	PF02991	0.370
LIG_LIR_Nem_3	988	992	PF02991	0.594
LIG_MAD2	917	925	PF02301	0.519
LIG_MLH1_MIPbox_1	838	842	PF16413	0.537
LIG_MLH1_MIPbox_1	885	889	PF16413	0.560
LIG_NRBOX	124	130	PF00104	0.399
LIG_NRBOX	368	374	PF00104	0.662
LIG_NRBOX	621	627	PF00104	0.496
LIG_PCNA_yPIPBox_3	308	322	PF02747	0.473
LIG_PDZ_Class_1	1140	1145	PF00595	0.551
LIG_Pex14_1	760	764	PF04695	0.686
LIG_Pex14_2	566	570	PF04695	0.494
LIG_Pex14_2	889	893	PF04695	0.431
LIG_Pex14_2	923	927	PF04695	0.479
LIG_PTB_Apo_2	226	233	PF02174	0.406
LIG_PTB_Apo_2	887	894	PF02174	0.428
LIG_PTB_Apo_2	921	928	PF02174	0.445
LIG_PTB_Phospho_1	226	232	PF10480	0.400
LIG_REV1ctd_RIR_1	839	847	PF16727	0.574
LIG_SH2_CRK	232	236	PF00017	0.587
LIG_SH2_CRK	532	536	PF00017	0.515
LIG_SH2_CRK	541	545	PF00017	0.463
LIG_SH2_CRK	855	859	PF00017	0.528
LIG_SH2_CRK	989	993	PF00017	0.695
LIG_SH2_GRB2like	532	535	PF00017	0.536
LIG_SH2_GRB2like	74	77	PF00017	0.718
LIG_SH2_NCK_1	64	68	PF00017	0.585
LIG_SH2_NCK_1	989	993	PF00017	0.695
LIG_SH2_SRC	74	77	PF00017	0.631
LIG_SH2_STAP1	664	668	PF00017	0.610
LIG_SH2_STAT3	314	317	PF00017	0.442
LIG_SH2_STAT5	199	202	PF00017	0.494
LIG_SH2_STAT5	551	554	PF00017	0.448
LIG_SH2_STAT5	614	617	PF00017	0.362
LIG_SH2_STAT5	954	957	PF00017	0.546
LIG_SH2_STAT5	975	978	PF00017	0.594
LIG_SH2_STAT5	989	992	PF00017	0.698
LIG_SH3_3	1128	1134	PF00018	0.761
LIG_SH3_3	520	526	PF00018	0.558
LIG_SH3_3	565	571	PF00018	0.608
LIG_SUMO_SIM_anti_2	222	228	PF11976	0.491
LIG_SUMO_SIM_anti_2	606	613	PF11976	0.438
LIG_SUMO_SIM_anti_2	617	624	PF11976	0.422
LIG_SUMO_SIM_par_1	10	16	PF11976	0.561
LIG_SUMO_SIM_par_1	191	198	PF11976	0.404
LIG_SUMO_SIM_par_1	519	525	PF11976	0.598
LIG_SUMO_SIM_par_1	578	584	PF11976	0.409
LIG_SUMO_SIM_par_1	617	624	PF11976	0.464
LIG_TRAF2_1	347	350	PF00917	0.534
LIG_TYR_ITIM	539	544	PF00017	0.405
LIG_TYR_ITIM	853	858	PF00017	0.511
LIG_TYR_ITIM	973	978	PF00017	0.638
LIG_UBA3_1	121	127	PF00899	0.404
LIG_UBA3_1	149	154	PF00899	0.546
LIG_WRC_WIRS_1	477	482	PF05994	0.493
LIG_WRC_WIRS_1	487	492	PF05994	0.447
LIG_WRC_WIRS_1	593	598	PF05994	0.488
LIG_WRC_WIRS_1	679	684	PF05994	0.469
MOD_CDC14_SPxK_1	364	367	PF00782	0.651
MOD_CDK_SPK_2	844	849	PF00069	0.539
MOD_CDK_SPxK_1	361	367	PF00069	0.652
MOD_CDK_SPxxK_3	1015	1022	PF00069	0.642
MOD_CK1_1	1015	1021	PF00069	0.723
MOD_CK1_1	13	19	PF00069	0.413
MOD_CK1_1	26	32	PF00069	0.521
MOD_CK1_1	300	306	PF00069	0.630
MOD_CK1_1	361	367	PF00069	0.711
MOD_CK1_1	409	415	PF00069	0.732
MOD_CK1_1	517	523	PF00069	0.596
MOD_CK1_1	591	597	PF00069	0.342
MOD_CK1_1	662	668	PF00069	0.482
MOD_CK1_1	729	735	PF00069	0.744
MOD_CK1_1	767	773	PF00069	0.716
MOD_CK1_1	818	824	PF00069	0.631
MOD_CK1_1	828	834	PF00069	0.560
MOD_CK2_1	1043	1049	PF00069	0.740
MOD_CK2_1	137	143	PF00069	0.585
MOD_CK2_1	175	181	PF00069	0.496
MOD_CK2_1	243	249	PF00069	0.597
MOD_CK2_1	26	32	PF00069	0.588
MOD_CK2_1	829	835	PF00069	0.548
MOD_CK2_1	86	92	PF00069	0.589
MOD_CK2_1	973	979	PF00069	0.509
MOD_GlcNHglycan	1	4	PF01048	0.632
MOD_GlcNHglycan	1031	1034	PF01048	0.796
MOD_GlcNHglycan	1100	1106	PF01048	0.796
MOD_GlcNHglycan	1109	1112	PF01048	0.746
MOD_GlcNHglycan	139	142	PF01048	0.528
MOD_GlcNHglycan	265	269	PF01048	0.748
MOD_GlcNHglycan	297	300	PF01048	0.648
MOD_GlcNHglycan	409	412	PF01048	0.709
MOD_GlcNHglycan	474	477	PF01048	0.441
MOD_GlcNHglycan	516	519	PF01048	0.499
MOD_GlcNHglycan	528	531	PF01048	0.494
MOD_GlcNHglycan	577	580	PF01048	0.520
MOD_GlcNHglycan	731	734	PF01048	0.743
MOD_GlcNHglycan	770	773	PF01048	0.654
MOD_GlcNHglycan	779	782	PF01048	0.753
MOD_GlcNHglycan	838	841	PF01048	0.559
MOD_GlcNHglycan	948	951	PF01048	0.541
MOD_GSK3_1	1029	1036	PF00069	0.751
MOD_GSK3_1	1039	1046	PF00069	0.671
MOD_GSK3_1	13	20	PF00069	0.492
MOD_GSK3_1	293	300	PF00069	0.640
MOD_GSK3_1	357	364	PF00069	0.649
MOD_GSK3_1	407	414	PF00069	0.753
MOD_GSK3_1	468	475	PF00069	0.574
MOD_GSK3_1	517	524	PF00069	0.560
MOD_GSK3_1	558	565	PF00069	0.561
MOD_GSK3_1	575	582	PF00069	0.320
MOD_GSK3_1	588	595	PF00069	0.366
MOD_GSK3_1	764	771	PF00069	0.718
MOD_GSK3_1	804	811	PF00069	0.699
MOD_GSK3_1	815	822	PF00069	0.577
MOD_GSK3_1	825	832	PF00069	0.586
MOD_GSK3_1	849	856	PF00069	0.485
MOD_GSK3_1	946	953	PF00069	0.602
MOD_GSK3_1	957	964	PF00069	0.530
MOD_GSK3_1	969	976	PF00069	0.521
MOD_GSK3_1	981	988	PF00069	0.629
MOD_GSK3_1	992	999	PF00069	0.547
MOD_LATS_1	262	268	PF00433	0.706
MOD_N-GLC_1	1107	1112	PF02516	0.692
MOD_N-GLC_1	115	120	PF02516	0.461
MOD_N-GLC_1	230	235	PF02516	0.492
MOD_N-GLC_1	258	263	PF02516	0.649
MOD_N-GLC_1	726	731	PF02516	0.737
MOD_N-GLC_1	822	827	PF02516	0.596
MOD_N-GLC_1	849	854	PF02516	0.513
MOD_NEK2_1	1057	1062	PF00069	0.662
MOD_NEK2_1	117	122	PF00069	0.448
MOD_NEK2_1	17	22	PF00069	0.423
MOD_NEK2_1	297	302	PF00069	0.611
MOD_NEK2_1	488	493	PF00069	0.418
MOD_NEK2_1	588	593	PF00069	0.439
MOD_NEK2_1	621	626	PF00069	0.407
MOD_NEK2_1	643	648	PF00069	0.385
MOD_NEK2_1	680	685	PF00069	0.369
MOD_NEK2_1	764	769	PF00069	0.730
MOD_NEK2_1	853	858	PF00069	0.417
MOD_NEK2_1	957	962	PF00069	0.462
MOD_NEK2_1	973	978	PF00069	0.503
MOD_NEK2_1	987	992	PF00069	0.538
MOD_NEK2_2	418	423	PF00069	0.750
MOD_PIKK_1	1034	1040	PF00454	0.802
MOD_PIKK_1	1055	1061	PF00454	0.581
MOD_PIKK_1	809	815	PF00454	0.748
MOD_PK_1	815	821	PF00069	0.742
MOD_PK_1	934	940	PF00069	0.608
MOD_PKA_1	382	388	PF00069	0.628
MOD_PKA_2	1038	1044	PF00069	0.740
MOD_PKA_2	137	143	PF00069	0.585
MOD_PKA_2	243	249	PF00069	0.593
MOD_PKA_2	263	269	PF00069	0.593
MOD_PKA_2	300	306	PF00069	0.666
MOD_PKA_2	406	412	PF00069	0.638
MOD_PKA_2	501	507	PF00069	0.525
MOD_PKA_2	808	814	PF00069	0.726
MOD_PKA_2	961	967	PF00069	0.618
MOD_Plk_1	1004	1010	PF00069	0.741
MOD_Plk_1	230	236	PF00069	0.527
MOD_Plk_1	293	299	PF00069	0.711
MOD_Plk_1	46	52	PF00069	0.553
MOD_Plk_1	606	612	PF00069	0.530
MOD_Plk_1	662	668	PF00069	0.477
MOD_Plk_1	726	732	PF00069	0.700
MOD_Plk_1	764	770	PF00069	0.670
MOD_Plk_1	786	792	PF00069	0.692
MOD_Plk_1	822	828	PF00069	0.701
MOD_Plk_1	849	855	PF00069	0.495
MOD_Plk_1	957	963	PF00069	0.472
MOD_Plk_1	973	979	PF00069	0.428
MOD_Plk_2-3	284	290	PF00069	0.647
MOD_Plk_2-3	726	732	PF00069	0.752
MOD_Plk_2-3	736	742	PF00069	0.720
MOD_Plk_4	117	123	PF00069	0.437
MOD_Plk_4	192	198	PF00069	0.407
MOD_Plk_4	26	32	PF00069	0.526
MOD_Plk_4	338	344	PF00069	0.490
MOD_Plk_4	352	358	PF00069	0.579
MOD_Plk_4	368	374	PF00069	0.651
MOD_Plk_4	418	424	PF00069	0.646
MOD_Plk_4	592	598	PF00069	0.440
MOD_Plk_4	606	612	PF00069	0.365
MOD_Plk_4	621	627	PF00069	0.383
MOD_Plk_4	643	649	PF00069	0.390
MOD_Plk_4	870	876	PF00069	0.478
MOD_Plk_4	883	889	PF00069	0.428
MOD_Plk_4	934	940	PF00069	0.670
MOD_Plk_4	950	956	PF00069	0.477
MOD_Plk_4	973	979	PF00069	0.525
MOD_ProDKin_1	1015	1021	PF00069	0.650
MOD_ProDKin_1	361	367	PF00069	0.721
MOD_ProDKin_1	454	460	PF00069	0.665
MOD_ProDKin_1	522	528	PF00069	0.597
MOD_ProDKin_1	844	850	PF00069	0.532
MOD_SUMO_for_1	1001	1004	PF00179	0.762
MOD_SUMO_for_1	257	260	PF00179	0.538
MOD_SUMO_for_1	559	562	PF00179	0.537
MOD_SUMO_rev_2	265	273	PF00179	0.700
MOD_SUMO_rev_2	501	510	PF00179	0.568
MOD_SUMO_rev_2	770	779	PF00179	0.742
MOD_SUMO_rev_2	974	983	PF00179	0.495
TRG_DiLeu_BaEn_1	161	166	PF01217	0.412
TRG_DiLeu_BaEn_1	617	622	PF01217	0.448
TRG_DiLeu_BaEn_4	349	355	PF01217	0.545
TRG_DiLeu_BaLyEn_6	105	110	PF01217	0.404
TRG_DiLeu_BaLyEn_6	40	45	PF01217	0.540
TRG_ENDOCYTIC_2	232	235	PF00928	0.492
TRG_ENDOCYTIC_2	453	456	PF00928	0.686
TRG_ENDOCYTIC_2	532	535	PF00928	0.441
TRG_ENDOCYTIC_2	541	544	PF00928	0.334
TRG_ENDOCYTIC_2	551	554	PF00928	0.256
TRG_ENDOCYTIC_2	855	858	PF00928	0.519
TRG_ENDOCYTIC_2	920	923	PF00928	0.427
TRG_ENDOCYTIC_2	954	957	PF00928	0.558
TRG_ENDOCYTIC_2	975	978	PF00928	0.489
TRG_ENDOCYTIC_2	989	992	PF00928	0.614
TRG_ER_diArg_1	1076	1079	PF00400	0.763
TRG_ER_diArg_1	1087	1089	PF00400	0.795
TRG_ER_diArg_1	40	43	PF00400	0.422
TRG_ER_diArg_1	428	430	PF00400	0.707
TRG_ER_diArg_1	442	445	PF00400	0.531
TRG_ER_diArg_1	48	51	PF00400	0.468
TRG_ER_diArg_1	602	605	PF00400	0.423
TRG_NLS_Bipartite_1	1069	1090	PF00514	0.762
TRG_NLS_Bipartite_1	429	448	PF00514	0.663
TRG_NLS_MonoCore_2	1085	1090	PF00514	0.780
TRG_NLS_MonoExtC_3	1085	1091	PF00514	0.825
TRG_NLS_MonoExtC_3	442	447	PF00514	0.568
TRG_NLS_MonoExtN_4	1085	1090	PF00514	0.835
TRG_NLS_MonoExtN_4	443	448	PF00514	0.568
TRG_NLS_MonoExtN_4	700	705	PF00514	0.606
TRG_Pf-PMV_PEXEL_1	308	312	PF00026	0.675
TRG_Pf-PMV_PEXEL_1	43	47	PF00026	0.438
TRG_Pf-PMV_PEXEL_1	553	557	PF00026	0.506

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PC20	Leptomonas seymouri	63%	100%
A0A3S7WU73	Leishmania donovani	90%	100%
A0A422N424	Trypanosoma rangeli	41%	100%
A4H8T1	Leishmania braziliensis	75%	100%
A4HX50	Leishmania infantum	90%	100%
C9ZVU2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
E9AQW5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
V5BS96	Trypanosoma cruzi	40%	100%