LeishMANIAdb
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DNA polymerase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
DNA polymerase
Gene product:
DNA polymerase I alpha catalytic subunit, putative
Species:
Leishmania major
UniProt:
Q4QEL1_LEIMA
TriTrypDb:
LmjF.16.1540 , LMJLV39_160022300 * , LMJSD75_160022000 *
Length:
1339

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0000428 DNA-directed RNA polymerase complex 4 2
GO:0005658 alpha DNA polymerase:primase complex 4 2
GO:0030880 RNA polymerase complex 3 2
GO:0032991 protein-containing complex 1 2
GO:0042575 DNA polymerase complex 3 2
GO:0055029 nuclear DNA-directed RNA polymerase complex 3 2
GO:0061695 transferase complex, transferring phosphorus-containing groups 4 2
GO:0140513 nuclear protein-containing complex 2 2
GO:0140535 intracellular protein-containing complex 2 2
GO:1902494 catalytic complex 2 2
GO:1990234 transferase complex 3 2
GO:0005634 nucleus 5 10
GO:0043226 organelle 2 10
GO:0043227 membrane-bounded organelle 3 10
GO:0043229 intracellular organelle 3 10
GO:0043231 intracellular membrane-bounded organelle 4 10
GO:0110165 cellular anatomical entity 1 10

Expansion

Sequence features

Q4QEL1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 12
GO:0006259 DNA metabolic process 4 12
GO:0006270 DNA replication initiation 5 12
GO:0006271 DNA strand elongation involved in DNA replication 6 2
GO:0006272 leading strand elongation 7 2
GO:0006273 lagging strand elongation 7 2
GO:0006725 cellular aromatic compound metabolic process 3 12
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0009987 cellular process 1 12
GO:0022402 cell cycle process 2 12
GO:0022616 DNA strand elongation 5 2
GO:0034641 cellular nitrogen compound metabolic process 3 12
GO:0043170 macromolecule metabolic process 3 12
GO:0044237 cellular metabolic process 2 12
GO:0044238 primary metabolic process 2 12
GO:0044260 obsolete cellular macromolecule metabolic process 3 12
GO:0046483 heterocycle metabolic process 3 12
GO:0071704 organic substance metabolic process 2 12
GO:0090304 nucleic acid metabolic process 4 12
GO:1901360 organic cyclic compound metabolic process 3 12
GO:1902292 cell cycle DNA replication initiation 3 12
GO:1902315 nuclear cell cycle DNA replication initiation 4 12
GO:1902975 mitotic DNA replication initiation 4 12
GO:1903047 mitotic cell cycle process 3 12
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 12
GO:0003676 nucleic acid binding 3 12
GO:0003677 DNA binding 4 12
GO:0003682 chromatin binding 2 2
GO:0003688 DNA replication origin binding 7 2
GO:0003690 double-stranded DNA binding 5 2
GO:0003697 single-stranded DNA binding 5 2
GO:0003824 catalytic activity 1 12
GO:0003887 DNA-directed DNA polymerase activity 5 12
GO:0005488 binding 1 12
GO:0016740 transferase activity 2 12
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 12
GO:0016779 nucleotidyltransferase activity 4 12
GO:0017076 purine nucleotide binding 4 2
GO:0019103 pyrimidine nucleotide binding 4 2
GO:0034061 DNA polymerase activity 4 12
GO:0036094 small molecule binding 2 12
GO:0043565 sequence-specific DNA binding 5 2
GO:0097159 organic cyclic compound binding 2 12
GO:0140097 catalytic activity, acting on DNA 3 12
GO:0140640 catalytic activity, acting on a nucleic acid 2 12
GO:1901265 nucleoside phosphate binding 3 12
GO:1901363 heterocyclic compound binding 2 12
GO:1990837 sequence-specific double-stranded DNA binding 6 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 126 130 PF00656 0.663
CLV_C14_Caspase3-7 439 443 PF00656 0.312
CLV_C14_Caspase3-7 813 817 PF00656 0.323
CLV_C14_Caspase3-7 827 831 PF00656 0.251
CLV_NRD_NRD_1 1060 1062 PF00675 0.289
CLV_NRD_NRD_1 1215 1217 PF00675 0.311
CLV_NRD_NRD_1 1284 1286 PF00675 0.330
CLV_NRD_NRD_1 1291 1293 PF00675 0.302
CLV_NRD_NRD_1 13 15 PF00675 0.685
CLV_NRD_NRD_1 321 323 PF00675 0.263
CLV_NRD_NRD_1 382 384 PF00675 0.386
CLV_NRD_NRD_1 504 506 PF00675 0.335
CLV_NRD_NRD_1 543 545 PF00675 0.380
CLV_NRD_NRD_1 66 68 PF00675 0.571
CLV_NRD_NRD_1 726 728 PF00675 0.242
CLV_NRD_NRD_1 818 820 PF00675 0.241
CLV_NRD_NRD_1 979 981 PF00675 0.241
CLV_PCSK_KEX2_1 1284 1286 PF00082 0.351
CLV_PCSK_KEX2_1 1291 1293 PF00082 0.331
CLV_PCSK_KEX2_1 1323 1325 PF00082 0.266
CLV_PCSK_KEX2_1 321 323 PF00082 0.256
CLV_PCSK_KEX2_1 382 384 PF00082 0.302
CLV_PCSK_KEX2_1 504 506 PF00082 0.282
CLV_PCSK_KEX2_1 543 545 PF00082 0.374
CLV_PCSK_KEX2_1 562 564 PF00082 0.133
CLV_PCSK_KEX2_1 669 671 PF00082 0.267
CLV_PCSK_KEX2_1 715 717 PF00082 0.274
CLV_PCSK_KEX2_1 726 728 PF00082 0.242
CLV_PCSK_KEX2_1 818 820 PF00082 0.241
CLV_PCSK_KEX2_1 822 824 PF00082 0.241
CLV_PCSK_KEX2_1 929 931 PF00082 0.387
CLV_PCSK_KEX2_1 979 981 PF00082 0.276
CLV_PCSK_KEX2_1 98 100 PF00082 0.577
CLV_PCSK_PC1ET2_1 1323 1325 PF00082 0.344
CLV_PCSK_PC1ET2_1 382 384 PF00082 0.302
CLV_PCSK_PC1ET2_1 562 564 PF00082 0.301
CLV_PCSK_PC1ET2_1 669 671 PF00082 0.267
CLV_PCSK_PC1ET2_1 715 717 PF00082 0.274
CLV_PCSK_PC1ET2_1 726 728 PF00082 0.256
CLV_PCSK_PC1ET2_1 822 824 PF00082 0.241
CLV_PCSK_PC1ET2_1 929 931 PF00082 0.387
CLV_PCSK_PC1ET2_1 98 100 PF00082 0.577
CLV_PCSK_PC7_1 558 564 PF00082 0.256
CLV_PCSK_PC7_1 818 824 PF00082 0.241
CLV_PCSK_SKI1_1 1035 1039 PF00082 0.256
CLV_PCSK_SKI1_1 1182 1186 PF00082 0.413
CLV_PCSK_SKI1_1 1260 1264 PF00082 0.264
CLV_PCSK_SKI1_1 182 186 PF00082 0.578
CLV_PCSK_SKI1_1 290 294 PF00082 0.306
CLV_PCSK_SKI1_1 321 325 PF00082 0.301
CLV_PCSK_SKI1_1 363 367 PF00082 0.262
CLV_PCSK_SKI1_1 383 387 PF00082 0.182
CLV_PCSK_SKI1_1 510 514 PF00082 0.256
CLV_PCSK_SKI1_1 61 65 PF00082 0.515
CLV_PCSK_SKI1_1 669 673 PF00082 0.280
CLV_PCSK_SKI1_1 681 685 PF00082 0.256
CLV_PCSK_SKI1_1 703 707 PF00082 0.241
CLV_PCSK_SKI1_1 727 731 PF00082 0.339
CLV_PCSK_SKI1_1 804 808 PF00082 0.241
CLV_PCSK_SKI1_1 809 813 PF00082 0.241
CLV_PCSK_SKI1_1 819 823 PF00082 0.241
CLV_PCSK_SKI1_1 842 846 PF00082 0.256
CLV_PCSK_SKI1_1 876 880 PF00082 0.241
CLV_PCSK_SKI1_1 943 947 PF00082 0.241
CLV_PCSK_SKI1_1 95 99 PF00082 0.528
CLV_PCSK_SKI1_1 970 974 PF00082 0.260
CLV_Separin_Metazoa 1063 1067 PF03568 0.387
DEG_APCC_DBOX_1 1060 1068 PF00400 0.387
DEG_APCC_DBOX_1 362 370 PF00400 0.262
DEG_APCC_DBOX_1 557 565 PF00400 0.387
DOC_CKS1_1 1183 1188 PF01111 0.436
DOC_CKS1_1 483 488 PF01111 0.368
DOC_CKS1_1 629 634 PF01111 0.494
DOC_CKS1_1 704 709 PF01111 0.241
DOC_CYCLIN_RxL_1 1257 1264 PF00134 0.278
DOC_CYCLIN_RxL_1 839 850 PF00134 0.256
DOC_CYCLIN_yCln2_LP_2 1183 1189 PF00134 0.387
DOC_MAPK_gen_1 1059 1067 PF00069 0.241
DOC_MAPK_gen_1 1201 1211 PF00069 0.320
DOC_MAPK_gen_1 1323 1330 PF00069 0.264
DOC_MAPK_gen_1 382 393 PF00069 0.275
DOC_MAPK_gen_1 543 550 PF00069 0.387
DOC_MAPK_gen_1 687 696 PF00069 0.241
DOC_MAPK_gen_1 726 737 PF00069 0.243
DOC_MAPK_gen_1 773 781 PF00069 0.240
DOC_MAPK_gen_1 826 836 PF00069 0.329
DOC_MAPK_gen_1 914 923 PF00069 0.320
DOC_MAPK_gen_1 926 936 PF00069 0.265
DOC_MAPK_gen_1 949 958 PF00069 0.241
DOC_MAPK_gen_1 98 108 PF00069 0.453
DOC_MAPK_MEF2A_6 1204 1213 PF00069 0.327
DOC_MAPK_MEF2A_6 1323 1332 PF00069 0.249
DOC_MAPK_MEF2A_6 639 648 PF00069 0.348
DOC_MAPK_MEF2A_6 914 923 PF00069 0.350
DOC_MAPK_MEF2A_6 929 938 PF00069 0.168
DOC_MAPK_RevD_3 936 952 PF00069 0.241
DOC_PP1_RVXF_1 319 326 PF00149 0.256
DOC_PP2B_LxvP_1 425 428 PF13499 0.387
DOC_PP2B_LxvP_1 51 54 PF13499 0.541
DOC_PP2B_LxvP_1 797 800 PF13499 0.339
DOC_PP4_FxxP_1 1263 1266 PF00568 0.266
DOC_PP4_FxxP_1 226 229 PF00568 0.441
DOC_PP4_FxxP_1 293 296 PF00568 0.256
DOC_PP4_FxxP_1 332 335 PF00568 0.241
DOC_PP4_FxxP_1 704 707 PF00568 0.241
DOC_USP7_MATH_1 1000 1004 PF00917 0.387
DOC_USP7_MATH_1 151 155 PF00917 0.518
DOC_USP7_MATH_1 232 236 PF00917 0.555
DOC_USP7_MATH_1 298 302 PF00917 0.262
DOC_USP7_MATH_1 371 375 PF00917 0.241
DOC_USP7_MATH_1 625 629 PF00917 0.519
DOC_USP7_MATH_1 657 661 PF00917 0.402
DOC_USP7_MATH_1 878 882 PF00917 0.387
DOC_USP7_UBL2_3 1035 1039 PF12436 0.241
DOC_USP7_UBL2_3 382 386 PF12436 0.335
DOC_USP7_UBL2_3 60 64 PF12436 0.541
DOC_USP7_UBL2_3 726 730 PF12436 0.243
DOC_USP7_UBL2_3 74 78 PF12436 0.634
DOC_USP7_UBL2_3 822 826 PF12436 0.241
DOC_USP7_UBL2_3 910 914 PF12436 0.335
DOC_USP7_UBL2_3 966 970 PF12436 0.248
DOC_WW_Pin1_4 1182 1187 PF00397 0.436
DOC_WW_Pin1_4 203 208 PF00397 0.446
DOC_WW_Pin1_4 225 230 PF00397 0.560
DOC_WW_Pin1_4 396 401 PF00397 0.340
DOC_WW_Pin1_4 411 416 PF00397 0.223
DOC_WW_Pin1_4 482 487 PF00397 0.259
DOC_WW_Pin1_4 628 633 PF00397 0.505
DOC_WW_Pin1_4 703 708 PF00397 0.241
DOC_WW_Pin1_4 73 78 PF00397 0.722
LIG_14-3-3_CanoR_1 1025 1029 PF00244 0.262
LIG_14-3-3_CanoR_1 1045 1050 PF00244 0.215
LIG_14-3-3_CanoR_1 1080 1088 PF00244 0.380
LIG_14-3-3_CanoR_1 1092 1099 PF00244 0.199
LIG_14-3-3_CanoR_1 1216 1220 PF00244 0.310
LIG_14-3-3_CanoR_1 1253 1259 PF00244 0.262
LIG_14-3-3_CanoR_1 1291 1297 PF00244 0.330
LIG_14-3-3_CanoR_1 275 279 PF00244 0.429
LIG_14-3-3_CanoR_1 402 410 PF00244 0.235
LIG_14-3-3_CanoR_1 479 484 PF00244 0.333
LIG_14-3-3_CanoR_1 603 608 PF00244 0.340
LIG_14-3-3_CanoR_1 670 678 PF00244 0.268
LIG_14-3-3_CanoR_1 930 935 PF00244 0.256
LIG_Actin_WH2_2 378 394 PF00022 0.387
LIG_Actin_WH2_2 688 705 PF00022 0.241
LIG_Actin_WH2_2 830 847 PF00022 0.241
LIG_Actin_WH2_2 879 896 PF00022 0.275
LIG_APCC_ABBA_1 455 460 PF00400 0.275
LIG_APCC_ABBAyCdc20_2 740 746 PF00400 0.241
LIG_BRCT_BRCA1_1 1155 1159 PF00533 0.387
LIG_BRCT_BRCA1_1 174 178 PF00533 0.521
LIG_BRCT_BRCA1_1 619 623 PF00533 0.399
LIG_CaM_NSCaTE_8 679 686 PF13499 0.275
LIG_CtBP_PxDLS_1 974 980 PF00389 0.241
LIG_eIF4E_1 744 750 PF01652 0.241
LIG_EVH1_1 425 429 PF00568 0.387
LIG_FHA_1 1051 1057 PF00498 0.335
LIG_FHA_1 164 170 PF00498 0.510
LIG_FHA_1 237 243 PF00498 0.439
LIG_FHA_1 252 258 PF00498 0.310
LIG_FHA_1 274 280 PF00498 0.446
LIG_FHA_1 535 541 PF00498 0.253
LIG_FHA_1 625 631 PF00498 0.469
LIG_FHA_1 654 660 PF00498 0.332
LIG_FHA_1 666 672 PF00498 0.208
LIG_FHA_1 880 886 PF00498 0.260
LIG_FHA_1 898 904 PF00498 0.365
LIG_FHA_2 1147 1153 PF00498 0.417
LIG_FHA_2 1293 1299 PF00498 0.342
LIG_FHA_2 134 140 PF00498 0.483
LIG_FHA_2 143 149 PF00498 0.425
LIG_FHA_2 22 28 PF00498 0.520
LIG_FHA_2 437 443 PF00498 0.312
LIG_FHA_2 696 702 PF00498 0.387
LIG_FHA_2 767 773 PF00498 0.256
LIG_FHA_2 825 831 PF00498 0.239
LIG_FHA_2 87 93 PF00498 0.642
LIG_FHA_2 955 961 PF00498 0.335
LIG_Integrin_isoDGR_2 273 275 PF01839 0.346
LIG_IRF3_LxIS_1 388 394 PF10401 0.306
LIG_LIR_Apic_2 291 296 PF02991 0.305
LIG_LIR_Apic_2 701 707 PF02991 0.335
LIG_LIR_Gen_1 1101 1112 PF02991 0.262
LIG_LIR_Gen_1 1326 1337 PF02991 0.262
LIG_LIR_Gen_1 342 350 PF02991 0.335
LIG_LIR_Gen_1 389 398 PF02991 0.264
LIG_LIR_Gen_1 551 561 PF02991 0.390
LIG_LIR_Gen_1 640 648 PF02991 0.349
LIG_LIR_Gen_1 692 699 PF02991 0.241
LIG_LIR_Gen_1 745 753 PF02991 0.241
LIG_LIR_Gen_1 858 867 PF02991 0.289
LIG_LIR_Nem_3 1101 1107 PF02991 0.264
LIG_LIR_Nem_3 1205 1210 PF02991 0.267
LIG_LIR_Nem_3 1231 1236 PF02991 0.392
LIG_LIR_Nem_3 1254 1259 PF02991 0.281
LIG_LIR_Nem_3 1319 1325 PF02991 0.279
LIG_LIR_Nem_3 1326 1332 PF02991 0.255
LIG_LIR_Nem_3 1333 1339 PF02991 0.240
LIG_LIR_Nem_3 240 246 PF02991 0.415
LIG_LIR_Nem_3 26 32 PF02991 0.525
LIG_LIR_Nem_3 327 332 PF02991 0.246
LIG_LIR_Nem_3 342 347 PF02991 0.256
LIG_LIR_Nem_3 389 393 PF02991 0.309
LIG_LIR_Nem_3 551 556 PF02991 0.377
LIG_LIR_Nem_3 595 600 PF02991 0.289
LIG_LIR_Nem_3 640 645 PF02991 0.318
LIG_LIR_Nem_3 692 696 PF02991 0.241
LIG_LIR_Nem_3 698 702 PF02991 0.241
LIG_LIR_Nem_3 745 750 PF02991 0.256
LIG_LIR_Nem_3 752 756 PF02991 0.266
LIG_LIR_Nem_3 850 855 PF02991 0.241
LIG_LIR_Nem_3 858 862 PF02991 0.241
LIG_LIR_Nem_3 939 945 PF02991 0.355
LIG_LIR_Nem_3 981 985 PF02991 0.241
LIG_LYPXL_S_1 1109 1113 PF13949 0.241
LIG_LYPXL_S_1 756 760 PF13949 0.241
LIG_LYPXL_yS_3 1110 1113 PF13949 0.241
LIG_LYPXL_yS_3 353 356 PF13949 0.306
LIG_LYPXL_yS_3 757 760 PF13949 0.241
LIG_MYND_1 887 891 PF01753 0.387
LIG_NRBOX 537 543 PF00104 0.335
LIG_Pex14_2 764 768 PF04695 0.387
LIG_SH2_CRK 1233 1237 PF00017 0.380
LIG_SH2_CRK 1259 1263 PF00017 0.409
LIG_SH2_CRK 289 293 PF00017 0.387
LIG_SH2_CRK 597 601 PF00017 0.301
LIG_SH2_CRK 602 606 PF00017 0.251
LIG_SH2_CRK 642 646 PF00017 0.370
LIG_SH2_CRK 852 856 PF00017 0.241
LIG_SH2_CRK 953 957 PF00017 0.241
LIG_SH2_GRB2like 201 204 PF00017 0.438
LIG_SH2_NCK_1 1294 1298 PF00017 0.342
LIG_SH2_PTP2 1210 1213 PF00017 0.408
LIG_SH2_PTP2 747 750 PF00017 0.256
LIG_SH2_STAP1 330 334 PF00017 0.262
LIG_SH2_STAP1 642 646 PF00017 0.401
LIG_SH2_STAP1 744 748 PF00017 0.241
LIG_SH2_STAT5 1009 1012 PF00017 0.275
LIG_SH2_STAT5 1026 1029 PF00017 0.196
LIG_SH2_STAT5 1073 1076 PF00017 0.241
LIG_SH2_STAT5 1104 1107 PF00017 0.241
LIG_SH2_STAT5 1210 1213 PF00017 0.357
LIG_SH2_STAT5 1223 1226 PF00017 0.215
LIG_SH2_STAT5 1294 1297 PF00017 0.283
LIG_SH2_STAT5 278 281 PF00017 0.488
LIG_SH2_STAT5 494 497 PF00017 0.264
LIG_SH2_STAT5 693 696 PF00017 0.241
LIG_SH2_STAT5 710 713 PF00017 0.241
LIG_SH2_STAT5 747 750 PF00017 0.243
LIG_SH3_2 1269 1274 PF14604 0.355
LIG_SH3_2 229 234 PF14604 0.614
LIG_SH3_3 1183 1189 PF00018 0.306
LIG_SH3_3 1263 1269 PF00018 0.283
LIG_SH3_3 13 19 PF00018 0.693
LIG_SH3_3 1304 1310 PF00018 0.379
LIG_SH3_3 183 189 PF00018 0.660
LIG_SH3_3 226 232 PF00018 0.601
LIG_SH3_3 332 338 PF00018 0.273
LIG_SH3_3 394 400 PF00018 0.325
LIG_SH3_3 409 415 PF00018 0.220
LIG_SH3_3 423 429 PF00018 0.241
LIG_SH3_3 51 57 PF00018 0.637
LIG_SH3_3 626 632 PF00018 0.514
LIG_SH3_3 733 739 PF00018 0.241
LIG_SH3_3 778 784 PF00018 0.263
LIG_SH3_4 74 81 PF00018 0.626
LIG_SH3_CIN85_PxpxPR_1 189 194 PF14604 0.459
LIG_SUMO_SIM_anti_2 537 542 PF11976 0.277
LIG_SUMO_SIM_anti_2 660 666 PF11976 0.412
LIG_SUMO_SIM_anti_2 745 752 PF11976 0.256
LIG_SUMO_SIM_anti_2 881 887 PF11976 0.260
LIG_SUMO_SIM_par_1 166 175 PF11976 0.505
LIG_SUMO_SIM_par_1 253 258 PF11976 0.488
LIG_SUMO_SIM_par_1 487 493 PF11976 0.335
LIG_SUMO_SIM_par_1 603 609 PF11976 0.311
LIG_SUMO_SIM_par_1 745 752 PF11976 0.241
LIG_TRAF2_1 1303 1306 PF00917 0.347
LIG_TYR_ITIM 600 605 PF00017 0.387
LIG_TYR_ITIM 691 696 PF00017 0.241
LIG_TYR_ITSM 1229 1236 PF00017 0.392
LIG_TYR_ITSM 1318 1325 PF00017 0.407
LIG_UBA3_1 375 382 PF00899 0.256
LIG_UBA3_1 836 842 PF00899 0.315
LIG_UBA3_1 945 952 PF00899 0.244
LIG_Vh1_VBS_1 634 652 PF01044 0.358
LIG_WRC_WIRS_1 696 701 PF05994 0.335
MOD_CDC14_SPxK_1 399 402 PF00782 0.175
MOD_CDK_SPK_2 203 208 PF00069 0.522
MOD_CDK_SPK_2 411 416 PF00069 0.256
MOD_CDK_SPK_2 73 78 PF00069 0.578
MOD_CDK_SPxK_1 396 402 PF00069 0.175
MOD_CDK_SPxK_1 703 709 PF00069 0.241
MOD_CDK_SPxxK_3 73 80 PF00069 0.580
MOD_CK1_1 1154 1160 PF00069 0.340
MOD_CK1_1 277 283 PF00069 0.383
MOD_CK1_1 411 417 PF00069 0.378
MOD_CK1_1 473 479 PF00069 0.296
MOD_CK1_1 482 488 PF00069 0.333
MOD_CK1_1 493 499 PF00069 0.275
MOD_CK1_1 551 557 PF00069 0.388
MOD_CK1_1 628 634 PF00069 0.438
MOD_CK1_1 992 998 PF00069 0.338
MOD_CK2_1 1292 1298 PF00069 0.390
MOD_CK2_1 133 139 PF00069 0.518
MOD_CK2_1 142 148 PF00069 0.472
MOD_CK2_1 28 34 PF00069 0.565
MOD_CK2_1 371 377 PF00069 0.253
MOD_CK2_1 814 820 PF00069 0.241
MOD_Cter_Amidation 724 727 PF01082 0.335
MOD_GlcNHglycan 1244 1247 PF01048 0.305
MOD_GlcNHglycan 181 185 PF01048 0.585
MOD_GlcNHglycan 393 396 PF01048 0.403
MOD_GlcNHglycan 47 50 PF01048 0.619
MOD_GlcNHglycan 495 498 PF01048 0.240
MOD_GlcNHglycan 57 60 PF01048 0.488
MOD_GlcNHglycan 635 638 PF01048 0.412
MOD_GlcNHglycan 70 73 PF01048 0.530
MOD_GlcNHglycan 797 800 PF01048 0.418
MOD_GSK3_1 1031 1038 PF00069 0.256
MOD_GSK3_1 1154 1161 PF00069 0.353
MOD_GSK3_1 1211 1218 PF00069 0.296
MOD_GSK3_1 159 166 PF00069 0.440
MOD_GSK3_1 232 239 PF00069 0.531
MOD_GSK3_1 273 280 PF00069 0.365
MOD_GSK3_1 436 443 PF00069 0.421
MOD_GSK3_1 548 555 PF00069 0.306
MOD_GSK3_1 586 593 PF00069 0.299
MOD_GSK3_1 6 13 PF00069 0.694
MOD_GSK3_1 624 631 PF00069 0.512
MOD_GSK3_1 653 660 PF00069 0.347
MOD_GSK3_1 665 672 PF00069 0.217
MOD_GSK3_1 752 759 PF00069 0.316
MOD_GSK3_1 80 87 PF00069 0.577
MOD_GSK3_1 810 817 PF00069 0.320
MOD_GSK3_1 985 992 PF00069 0.212
MOD_N-GLC_1 164 169 PF02516 0.585
MOD_N-GLC_1 548 553 PF02516 0.304
MOD_N-GLC_1 774 779 PF02516 0.240
MOD_N-GLC_2 765 767 PF02516 0.232
MOD_NEK2_1 1031 1036 PF00069 0.256
MOD_NEK2_1 1153 1158 PF00069 0.497
MOD_NEK2_1 1228 1233 PF00069 0.297
MOD_NEK2_1 213 218 PF00069 0.451
MOD_NEK2_1 288 293 PF00069 0.346
MOD_NEK2_1 369 374 PF00069 0.275
MOD_NEK2_1 391 396 PF00069 0.403
MOD_NEK2_1 451 456 PF00069 0.387
MOD_NEK2_1 548 553 PF00069 0.306
MOD_NEK2_1 567 572 PF00069 0.129
MOD_NEK2_1 695 700 PF00069 0.306
MOD_NEK2_1 814 819 PF00069 0.286
MOD_NEK2_1 84 89 PF00069 0.564
MOD_NEK2_1 844 849 PF00069 0.241
MOD_NEK2_1 857 862 PF00069 0.241
MOD_NEK2_1 904 909 PF00069 0.241
MOD_NEK2_1 985 990 PF00069 0.175
MOD_NEK2_2 1317 1322 PF00069 0.286
MOD_NEK2_2 679 684 PF00069 0.256
MOD_OFUCOSY 1227 1232 PF10250 0.312
MOD_PIKK_1 1092 1098 PF00454 0.277
MOD_PIKK_1 1199 1205 PF00454 0.275
MOD_PIKK_1 1226 1232 PF00454 0.263
MOD_PIKK_1 1251 1257 PF00454 0.351
MOD_PIKK_1 21 27 PF00454 0.593
MOD_PIKK_1 298 304 PF00454 0.262
MOD_PIKK_1 339 345 PF00454 0.262
MOD_PIKK_1 436 442 PF00454 0.253
MOD_PKA_1 669 675 PF00069 0.280
MOD_PKA_1 67 73 PF00069 0.521
MOD_PKA_2 10 16 PF00069 0.618
MOD_PKA_2 1024 1030 PF00069 0.262
MOD_PKA_2 1079 1085 PF00069 0.363
MOD_PKA_2 1215 1221 PF00069 0.459
MOD_PKA_2 142 148 PF00069 0.396
MOD_PKA_2 274 280 PF00069 0.466
MOD_PKA_2 391 397 PF00069 0.335
MOD_PKA_2 401 407 PF00069 0.191
MOD_PKA_2 665 671 PF00069 0.299
MOD_Plk_1 131 137 PF00069 0.612
MOD_Plk_1 163 169 PF00069 0.612
MOD_Plk_1 172 178 PF00069 0.565
MOD_Plk_1 339 345 PF00069 0.335
MOD_Plk_1 408 414 PF00069 0.387
MOD_Plk_1 463 469 PF00069 0.400
MOD_Plk_1 548 554 PF00069 0.340
MOD_Plk_1 857 863 PF00069 0.256
MOD_Plk_2-3 1146 1152 PF00069 0.457
MOD_Plk_2-3 774 780 PF00069 0.387
MOD_Plk_4 1154 1160 PF00069 0.362
MOD_Plk_4 1317 1323 PF00069 0.283
MOD_Plk_4 1331 1337 PF00069 0.260
MOD_Plk_4 164 170 PF00069 0.598
MOD_Plk_4 258 264 PF00069 0.362
MOD_Plk_4 274 280 PF00069 0.450
MOD_Plk_4 371 377 PF00069 0.301
MOD_Plk_4 386 392 PF00069 0.185
MOD_Plk_4 470 476 PF00069 0.457
MOD_Plk_4 625 631 PF00069 0.374
MOD_Plk_4 752 758 PF00069 0.241
MOD_Plk_4 810 816 PF00069 0.370
MOD_Plk_4 847 853 PF00069 0.241
MOD_Plk_4 899 905 PF00069 0.241
MOD_Plk_4 989 995 PF00069 0.397
MOD_ProDKin_1 1182 1188 PF00069 0.436
MOD_ProDKin_1 203 209 PF00069 0.444
MOD_ProDKin_1 225 231 PF00069 0.558
MOD_ProDKin_1 396 402 PF00069 0.340
MOD_ProDKin_1 411 417 PF00069 0.223
MOD_ProDKin_1 482 488 PF00069 0.259
MOD_ProDKin_1 628 634 PF00069 0.498
MOD_ProDKin_1 703 709 PF00069 0.241
MOD_ProDKin_1 73 79 PF00069 0.722
MOD_SUMO_for_1 1140 1143 PF00179 0.473
MOD_SUMO_for_1 171 174 PF00179 0.530
MOD_SUMO_for_1 825 828 PF00179 0.241
MOD_SUMO_rev_2 1195 1202 PF00179 0.292
MOD_SUMO_rev_2 421 426 PF00179 0.329
MOD_SUMO_rev_2 554 564 PF00179 0.301
MOD_SUMO_rev_2 816 824 PF00179 0.241
MOD_SUMO_rev_2 918 925 PF00179 0.311
MOD_SUMO_rev_2 960 967 PF00179 0.260
TRG_DiLeu_BaEn_1 820 825 PF01217 0.275
TRG_DiLeu_BaLyEn_6 600 605 PF01217 0.306
TRG_DiLeu_BaLyEn_6 92 97 PF01217 0.501
TRG_ENDOCYTIC_2 1104 1107 PF00928 0.265
TRG_ENDOCYTIC_2 1110 1113 PF00928 0.222
TRG_ENDOCYTIC_2 1210 1213 PF00928 0.297
TRG_ENDOCYTIC_2 1233 1236 PF00928 0.392
TRG_ENDOCYTIC_2 1259 1262 PF00928 0.409
TRG_ENDOCYTIC_2 1322 1325 PF00928 0.252
TRG_ENDOCYTIC_2 289 292 PF00928 0.387
TRG_ENDOCYTIC_2 329 332 PF00928 0.256
TRG_ENDOCYTIC_2 353 356 PF00928 0.275
TRG_ENDOCYTIC_2 458 461 PF00928 0.256
TRG_ENDOCYTIC_2 545 548 PF00928 0.275
TRG_ENDOCYTIC_2 597 600 PF00928 0.301
TRG_ENDOCYTIC_2 602 605 PF00928 0.251
TRG_ENDOCYTIC_2 642 645 PF00928 0.370
TRG_ENDOCYTIC_2 693 696 PF00928 0.241
TRG_ENDOCYTIC_2 747 750 PF00928 0.241
TRG_ENDOCYTIC_2 757 760 PF00928 0.241
TRG_ENDOCYTIC_2 852 855 PF00928 0.241
TRG_ENDOCYTIC_2 859 862 PF00928 0.241
TRG_ENDOCYTIC_2 931 934 PF00928 0.289
TRG_ENDOCYTIC_2 953 956 PF00928 0.241
TRG_ER_diArg_1 1291 1293 PF00400 0.413
TRG_ER_diArg_1 187 190 PF00400 0.563
TRG_ER_diArg_1 283 286 PF00400 0.387
TRG_ER_diArg_1 321 323 PF00400 0.256
TRG_ER_diArg_1 503 505 PF00400 0.335
TRG_ER_diArg_1 542 544 PF00400 0.380
TRG_ER_diArg_1 978 980 PF00400 0.241
TRG_NES_CRM1_1 1319 1333 PF08389 0.398
TRG_NES_CRM1_1 82 94 PF08389 0.568
TRG_NES_CRM1_1 912 922 PF08389 0.401
TRG_NLS_Bipartite_1 715 731 PF00514 0.280
TRG_NLS_MonoCore_2 948 953 PF00514 0.241
TRG_NLS_MonoExtC_3 381 386 PF00514 0.335
TRG_NLS_MonoExtC_3 63 68 PF00514 0.549
TRG_NLS_MonoExtC_3 725 730 PF00514 0.256
TRG_NLS_MonoExtC_3 97 103 PF00514 0.488
TRG_NLS_MonoExtN_4 382 387 PF00514 0.330
TRG_NLS_MonoExtN_4 61 68 PF00514 0.550
TRG_NLS_MonoExtN_4 726 731 PF00514 0.256
TRG_NLS_MonoExtN_4 949 954 PF00514 0.241
TRG_NLS_MonoExtN_4 95 102 PF00514 0.574
TRG_Pf-PMV_PEXEL_1 1162 1166 PF00026 0.290
TRG_Pf-PMV_PEXEL_1 1260 1264 PF00026 0.279
TRG_Pf-PMV_PEXEL_1 1285 1290 PF00026 0.275
TRG_Pf-PMV_PEXEL_1 30 34 PF00026 0.608
TRG_Pf-PMV_PEXEL_1 468 472 PF00026 0.327
TRG_Pf-PMV_PEXEL_1 510 514 PF00026 0.346
TRG_Pf-PMV_PEXEL_1 639 643 PF00026 0.325
TRG_Pf-PMV_PEXEL_1 917 922 PF00026 0.252
TRG_Pf-PMV_PEXEL_1 996 1001 PF00026 0.275

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I597 Leptomonas seymouri 81% 100%
A0A0S4IUC6 Bodo saltans 45% 95%
A0A1X0P042 Trypanosomatidae 60% 99%
A0A3R7MDF7 Trypanosoma rangeli 58% 100%
A0A3S5H6Z2 Leishmania donovani 96% 100%
A0A3S7X6W2 Leishmania donovani 25% 100%
A4H8T3 Leishmania braziliensis 89% 100%
A4HLN0 Leishmania braziliensis 26% 100%
A4HX52 Leishmania infantum 96% 100%
A4I965 Leishmania infantum 25% 100%
C9ZVT9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 57% 100%
E9AQW7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 96% 100%
E9B406 Leishmania mexicana (strain MHOM/GT/2001/U1103) 25% 100%
O00874 Leishmania donovani 96% 100%
O48653 Oryza sativa subsp. japonica 38% 87%
O89042 Rattus norvegicus 38% 92%
P09884 Homo sapiens 37% 92%
P13382 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 34% 91%
P26019 Drosophila melanogaster 34% 90%
P27727 Trypanosoma brucei brucei 57% 100%
P28040 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 34% 95%
P30315 Plasmodium falciparum (isolate K1 / Thailand) 25% 100%
P30316 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 25% 100%
P33609 Mus musculus 37% 91%
Q27152 Oxytricha trifallax 34% 88%
Q4Q418 Leishmania major 25% 100%
Q54SV8 Dictyostelium discoideum 33% 89%
Q94636 Sterkiella nova 35% 90%
Q9DE46 Xenopus laevis 38% 92%
Q9FHA3 Arabidopsis thaliana 37% 88%
V5B2M9 Trypanosoma cruzi 60% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS