LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

ATP pyrophosphate-lyase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP pyrophosphate-lyase
Gene product:
receptor-type adenylate cyclase a
Species:
Leishmania major
UniProt:
Q4QEI3_LEIMA
TriTrypDb:
LmjF.17.0200 , LMJLV39_170006100 , LMJSD75_170006400
Length:
1377

Annotations

LeishMANIAdb annotations

Carries an ATP pyrophosphate-lyase domain on its cytoplasmic segment. Likely acts as a receptor for some unknown extracellular stimulus. Extremely expanded kinetoplastid protein family.. Expressed in the insect stage (promastigote) but not in the mammalian host stage of the parasite life cycle.. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. yes yes: 57
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 46, no: 28
NetGPI no yes: 0, no: 74
Cellular components
Term Name Level Count
GO:0110165 cellular anatomical entity 1 75
GO:0016020 membrane 2 68

Expansion

Sequence features

Q4QEI3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 74
GO:0006163 purine nucleotide metabolic process 5 74
GO:0006164 purine nucleotide biosynthetic process 6 74
GO:0006171 cAMP biosynthetic process 8 74
GO:0006725 cellular aromatic compound metabolic process 3 74
GO:0006753 nucleoside phosphate metabolic process 4 74
GO:0006793 phosphorus metabolic process 3 74
GO:0006796 phosphate-containing compound metabolic process 4 74
GO:0006807 nitrogen compound metabolic process 2 74
GO:0007165 signal transduction 2 74
GO:0008152 metabolic process 1 74
GO:0009058 biosynthetic process 2 74
GO:0009117 nucleotide metabolic process 5 74
GO:0009150 purine ribonucleotide metabolic process 6 74
GO:0009152 purine ribonucleotide biosynthetic process 7 74
GO:0009165 nucleotide biosynthetic process 6 74
GO:0009187 cyclic nucleotide metabolic process 6 74
GO:0009190 cyclic nucleotide biosynthetic process 7 74
GO:0009259 ribonucleotide metabolic process 5 74
GO:0009260 ribonucleotide biosynthetic process 6 74
GO:0009987 cellular process 1 74
GO:0018130 heterocycle biosynthetic process 4 74
GO:0019438 aromatic compound biosynthetic process 4 74
GO:0019637 organophosphate metabolic process 3 74
GO:0019693 ribose phosphate metabolic process 4 74
GO:0034641 cellular nitrogen compound metabolic process 3 74
GO:0034654 nucleobase-containing compound biosynthetic process 4 74
GO:0035556 intracellular signal transduction 3 74
GO:0044237 cellular metabolic process 2 74
GO:0044238 primary metabolic process 2 74
GO:0044249 cellular biosynthetic process 3 74
GO:0044271 cellular nitrogen compound biosynthetic process 4 74
GO:0044281 small molecule metabolic process 2 74
GO:0046058 cAMP metabolic process 7 74
GO:0046390 ribose phosphate biosynthetic process 5 74
GO:0046483 heterocycle metabolic process 3 74
GO:0050789 regulation of biological process 2 74
GO:0050794 regulation of cellular process 3 74
GO:0052652 cyclic purine nucleotide metabolic process 6 74
GO:0055086 nucleobase-containing small molecule metabolic process 3 74
GO:0065007 biological regulation 1 74
GO:0071704 organic substance metabolic process 2 74
GO:0072521 purine-containing compound metabolic process 4 74
GO:0072522 purine-containing compound biosynthetic process 5 74
GO:0090407 organophosphate biosynthetic process 4 74
GO:1901135 carbohydrate derivative metabolic process 3 74
GO:1901137 carbohydrate derivative biosynthetic process 4 74
GO:1901293 nucleoside phosphate biosynthetic process 5 74
GO:1901360 organic cyclic compound metabolic process 3 74
GO:1901362 organic cyclic compound biosynthetic process 4 74
GO:1901564 organonitrogen compound metabolic process 3 74
GO:1901566 organonitrogen compound biosynthetic process 4 74
GO:1901576 organic substance biosynthetic process 3 74
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 64
GO:0016829 lyase activity 2 64
GO:0004016 adenylate cyclase activity 3 1
GO:0009975 cyclase activity 2 1
GO:0016849 phosphorus-oxygen lyase activity 3 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1009 1013 PF00656 0.557
CLV_C14_Caspase3-7 1250 1254 PF00656 0.699
CLV_C14_Caspase3-7 1332 1336 PF00656 0.704
CLV_C14_Caspase3-7 172 176 PF00656 0.434
CLV_C14_Caspase3-7 670 674 PF00656 0.364
CLV_C14_Caspase3-7 975 979 PF00656 0.488
CLV_MEL_PAP_1 1361 1367 PF00089 0.313
CLV_NRD_NRD_1 1138 1140 PF00675 0.421
CLV_NRD_NRD_1 202 204 PF00675 0.587
CLV_NRD_NRD_1 378 380 PF00675 0.511
CLV_NRD_NRD_1 599 601 PF00675 0.477
CLV_PCSK_FUR_1 200 204 PF00082 0.587
CLV_PCSK_KEX2_1 1138 1140 PF00082 0.421
CLV_PCSK_KEX2_1 1257 1259 PF00082 0.452
CLV_PCSK_KEX2_1 202 204 PF00082 0.588
CLV_PCSK_KEX2_1 307 309 PF00082 0.581
CLV_PCSK_KEX2_1 599 601 PF00082 0.504
CLV_PCSK_PC1ET2_1 1257 1259 PF00082 0.557
CLV_PCSK_PC1ET2_1 307 309 PF00082 0.606
CLV_PCSK_SKI1_1 1000 1004 PF00082 0.283
CLV_PCSK_SKI1_1 101 105 PF00082 0.699
CLV_PCSK_SKI1_1 1235 1239 PF00082 0.430
CLV_PCSK_SKI1_1 1373 1377 PF00082 0.341
CLV_PCSK_SKI1_1 203 207 PF00082 0.579
CLV_PCSK_SKI1_1 280 284 PF00082 0.530
CLV_PCSK_SKI1_1 300 304 PF00082 0.492
CLV_PCSK_SKI1_1 307 311 PF00082 0.477
CLV_PCSK_SKI1_1 802 806 PF00082 0.534
CLV_PCSK_SKI1_1 962 966 PF00082 0.226
DEG_APCC_DBOX_1 875 883 PF00400 0.326
DEG_Nend_UBRbox_3 1 3 PF02207 0.277
DEG_SCF_FBW7_2 865 872 PF00400 0.489
DEG_SPOP_SBC_1 285 289 PF00917 0.446
DEG_SPOP_SBC_1 330 334 PF00917 0.245
DEG_SPOP_SBC_1 793 797 PF00917 0.429
DOC_CDC14_PxL_1 589 597 PF14671 0.391
DOC_CKS1_1 866 871 PF01111 0.434
DOC_CYCLIN_RxL_1 304 314 PF00134 0.239
DOC_CYCLIN_yClb1_LxF_4 196 201 PF00134 0.186
DOC_CYCLIN_yCln2_LP_2 230 236 PF00134 0.336
DOC_CYCLIN_yCln2_LP_2 863 869 PF00134 0.436
DOC_MAPK_FxFP_2 486 489 PF00069 0.259
DOC_MAPK_gen_1 1046 1054 PF00069 0.510
DOC_MAPK_gen_1 198 206 PF00069 0.290
DOC_MAPK_gen_1 26 34 PF00069 0.526
DOC_MAPK_gen_1 596 605 PF00069 0.279
DOC_MAPK_MEF2A_6 181 190 PF00069 0.344
DOC_MAPK_MEF2A_6 497 506 PF00069 0.421
DOC_MAPK_RevD_3 1125 1139 PF00069 0.539
DOC_MAPK_RevD_3 188 203 PF00069 0.240
DOC_PP1_RVXF_1 196 202 PF00149 0.251
DOC_PP1_RVXF_1 298 304 PF00149 0.419
DOC_PP2B_LxvP_1 1343 1346 PF13499 0.497
DOC_PP2B_LxvP_1 160 163 PF13499 0.419
DOC_PP2B_LxvP_1 863 866 PF13499 0.502
DOC_PP4_FxxP_1 486 489 PF00568 0.447
DOC_PP4_FxxP_1 659 662 PF00568 0.413
DOC_PP4_FxxP_1 769 772 PF00568 0.282
DOC_SPAK_OSR1_1 432 436 PF12202 0.233
DOC_USP7_MATH_1 1010 1014 PF00917 0.606
DOC_USP7_MATH_1 1237 1241 PF00917 0.660
DOC_USP7_MATH_1 285 289 PF00917 0.445
DOC_USP7_MATH_1 330 334 PF00917 0.317
DOC_USP7_MATH_1 531 535 PF00917 0.372
DOC_USP7_MATH_1 662 666 PF00917 0.411
DOC_USP7_MATH_1 791 795 PF00917 0.368
DOC_USP7_MATH_1 983 987 PF00917 0.556
DOC_USP7_UBL2_3 189 193 PF12436 0.195
DOC_WW_Pin1_4 1073 1078 PF00397 0.532
DOC_WW_Pin1_4 326 331 PF00397 0.407
DOC_WW_Pin1_4 677 682 PF00397 0.350
DOC_WW_Pin1_4 773 778 PF00397 0.345
DOC_WW_Pin1_4 861 866 PF00397 0.391
DOC_WW_Pin1_4 880 885 PF00397 0.378
LIG_14-3-3_CanoR_1 1035 1041 PF00244 0.616
LIG_14-3-3_CanoR_1 1217 1224 PF00244 0.648
LIG_14-3-3_CanoR_1 1235 1240 PF00244 0.619
LIG_14-3-3_CanoR_1 1258 1267 PF00244 0.561
LIG_14-3-3_CanoR_1 1339 1346 PF00244 0.706
LIG_14-3-3_CanoR_1 171 179 PF00244 0.416
LIG_14-3-3_CanoR_1 286 293 PF00244 0.412
LIG_14-3-3_CanoR_1 308 317 PF00244 0.448
LIG_14-3-3_CanoR_1 321 331 PF00244 0.437
LIG_14-3-3_CanoR_1 420 424 PF00244 0.334
LIG_14-3-3_CanoR_1 474 479 PF00244 0.379
LIG_14-3-3_CanoR_1 624 628 PF00244 0.395
LIG_14-3-3_CanoR_1 638 646 PF00244 0.341
LIG_14-3-3_CanoR_1 725 731 PF00244 0.410
LIG_14-3-3_CanoR_1 738 743 PF00244 0.432
LIG_14-3-3_CanoR_1 985 993 PF00244 0.598
LIG_Actin_WH2_2 609 626 PF00022 0.211
LIG_Actin_WH2_2 710 727 PF00022 0.383
LIG_APCC_ABBA_1 136 141 PF00400 0.427
LIG_APCC_ABBA_1 717 722 PF00400 0.299
LIG_BIR_III_2 919 923 PF00653 0.643
LIG_BRCT_BRCA1_1 175 179 PF00533 0.366
LIG_BRCT_BRCA1_1 351 355 PF00533 0.264
LIG_BRCT_BRCA1_1 694 698 PF00533 0.427
LIG_deltaCOP1_diTrp_1 756 765 PF00928 0.453
LIG_DLG_GKlike_1 738 745 PF00625 0.264
LIG_FHA_1 1006 1012 PF00498 0.487
LIG_FHA_1 1031 1037 PF00498 0.497
LIG_FHA_1 1081 1087 PF00498 0.493
LIG_FHA_1 143 149 PF00498 0.306
LIG_FHA_1 28 34 PF00498 0.431
LIG_FHA_1 326 332 PF00498 0.307
LIG_FHA_1 412 418 PF00498 0.405
LIG_FHA_1 624 630 PF00498 0.337
LIG_FHA_1 631 637 PF00498 0.352
LIG_FHA_1 656 662 PF00498 0.323
LIG_FHA_1 670 676 PF00498 0.366
LIG_FHA_1 725 731 PF00498 0.368
LIG_FHA_1 774 780 PF00498 0.376
LIG_FHA_1 793 799 PF00498 0.305
LIG_FHA_1 803 809 PF00498 0.384
LIG_FHA_1 902 908 PF00498 0.386
LIG_FHA_1 997 1003 PF00498 0.552
LIG_FHA_2 1023 1029 PF00498 0.585
LIG_FHA_2 1143 1149 PF00498 0.735
LIG_FHA_2 1153 1159 PF00498 0.725
LIG_FHA_2 1171 1177 PF00498 0.569
LIG_FHA_2 1245 1251 PF00498 0.679
LIG_FHA_2 170 176 PF00498 0.424
LIG_FHA_2 178 184 PF00498 0.428
LIG_FHA_2 380 386 PF00498 0.372
LIG_FHA_2 478 484 PF00498 0.305
LIG_FHA_2 73 79 PF00498 0.413
LIG_FHA_2 749 755 PF00498 0.283
LIG_FHA_2 795 801 PF00498 0.307
LIG_FHA_2 82 88 PF00498 0.365
LIG_FHA_2 830 836 PF00498 0.413
LIG_FHA_2 932 938 PF00498 0.488
LIG_FHA_2 973 979 PF00498 0.492
LIG_GBD_Chelix_1 118 126 PF00786 0.619
LIG_GBD_Chelix_1 191 199 PF00786 0.389
LIG_GBD_Chelix_1 993 1001 PF00786 0.396
LIG_LIR_Apic_2 1027 1032 PF02991 0.478
LIG_LIR_Apic_2 443 447 PF02991 0.365
LIG_LIR_Apic_2 483 489 PF02991 0.442
LIG_LIR_Apic_2 658 662 PF02991 0.419
LIG_LIR_Gen_1 1012 1023 PF02991 0.462
LIG_LIR_Gen_1 1038 1048 PF02991 0.543
LIG_LIR_Gen_1 1060 1070 PF02991 0.586
LIG_LIR_Gen_1 238 248 PF02991 0.348
LIG_LIR_Gen_1 250 261 PF02991 0.329
LIG_LIR_Gen_1 477 486 PF02991 0.391
LIG_LIR_Gen_1 544 554 PF02991 0.346
LIG_LIR_Gen_1 695 706 PF02991 0.383
LIG_LIR_Gen_1 718 728 PF02991 0.281
LIG_LIR_Gen_1 741 747 PF02991 0.361
LIG_LIR_Gen_1 930 941 PF02991 0.489
LIG_LIR_Nem_3 1012 1018 PF02991 0.490
LIG_LIR_Nem_3 1038 1044 PF02991 0.490
LIG_LIR_Nem_3 1060 1066 PF02991 0.507
LIG_LIR_Nem_3 1067 1073 PF02991 0.467
LIG_LIR_Nem_3 1096 1102 PF02991 0.502
LIG_LIR_Nem_3 1186 1192 PF02991 0.631
LIG_LIR_Nem_3 238 244 PF02991 0.286
LIG_LIR_Nem_3 304 309 PF02991 0.370
LIG_LIR_Nem_3 352 358 PF02991 0.358
LIG_LIR_Nem_3 477 482 PF02991 0.322
LIG_LIR_Nem_3 512 517 PF02991 0.339
LIG_LIR_Nem_3 544 549 PF02991 0.377
LIG_LIR_Nem_3 695 701 PF02991 0.372
LIG_LIR_Nem_3 718 724 PF02991 0.310
LIG_LIR_Nem_3 741 745 PF02991 0.350
LIG_LIR_Nem_3 756 762 PF02991 0.349
LIG_LIR_Nem_3 836 842 PF02991 0.441
LIG_LIR_Nem_3 930 936 PF02991 0.489
LIG_LIR_Nem_3 940 946 PF02991 0.592
LIG_LYPXL_yS_3 514 517 PF13949 0.422
LIG_MLH1_MIPbox_1 175 179 PF16413 0.382
LIG_MYND_1 861 865 PF01753 0.385
LIG_MYND_3 606 610 PF01753 0.358
LIG_NRBOX 225 231 PF00104 0.231
LIG_NRBOX 674 680 PF00104 0.219
LIG_PCNA_TLS_4 380 387 PF02747 0.271
LIG_PCNA_yPIPBox_3 128 136 PF02747 0.229
LIG_PCNA_yPIPBox_3 216 230 PF02747 0.231
LIG_PCNA_yPIPBox_3 299 308 PF02747 0.314
LIG_Pex14_1 478 482 PF04695 0.197
LIG_Pex14_2 482 486 PF04695 0.436
LIG_Pex14_2 765 769 PF04695 0.285
LIG_PTB_Apo_2 1365 1372 PF02174 0.490
LIG_PTB_Apo_2 63 70 PF02174 0.391
LIG_PTB_Apo_2 803 810 PF02174 0.264
LIG_PTB_Phospho_1 1365 1371 PF10480 0.490
LIG_PTB_Phospho_1 63 69 PF10480 0.400
LIG_PTB_Phospho_1 803 809 PF10480 0.312
LIG_SH2_CRK 237 241 PF00017 0.417
LIG_SH2_CRK 306 310 PF00017 0.419
LIG_SH2_CRK 444 448 PF00017 0.363
LIG_SH2_GRB2like 809 812 PF00017 0.411
LIG_SH2_NCK_1 1063 1067 PF00017 0.580
LIG_SH2_NCK_1 116 120 PF00017 0.381
LIG_SH2_NCK_1 237 241 PF00017 0.430
LIG_SH2_NCK_1 617 621 PF00017 0.410
LIG_SH2_PTP2 1029 1032 PF00017 0.522
LIG_SH2_PTP2 602 605 PF00017 0.446
LIG_SH2_SRC 1029 1032 PF00017 0.535
LIG_SH2_SRC 1063 1066 PF00017 0.580
LIG_SH2_SRC 116 119 PF00017 0.363
LIG_SH2_SRC 139 142 PF00017 0.223
LIG_SH2_SRC 348 351 PF00017 0.323
LIG_SH2_SRC 809 812 PF00017 0.365
LIG_SH2_STAP1 1041 1045 PF00017 0.544
LIG_SH2_STAP1 1371 1375 PF00017 0.506
LIG_SH2_STAP1 565 569 PF00017 0.341
LIG_SH2_STAP1 69 73 PF00017 0.279
LIG_SH2_STAP1 91 95 PF00017 0.431
LIG_SH2_STAT3 460 463 PF00017 0.427
LIG_SH2_STAT3 91 94 PF00017 0.438
LIG_SH2_STAT5 1029 1032 PF00017 0.469
LIG_SH2_STAT5 1224 1227 PF00017 0.623
LIG_SH2_STAT5 139 142 PF00017 0.346
LIG_SH2_STAT5 178 181 PF00017 0.328
LIG_SH2_STAT5 221 224 PF00017 0.363
LIG_SH2_STAT5 291 294 PF00017 0.320
LIG_SH2_STAT5 348 351 PF00017 0.257
LIG_SH2_STAT5 381 384 PF00017 0.460
LIG_SH2_STAT5 439 442 PF00017 0.318
LIG_SH2_STAT5 460 463 PF00017 0.386
LIG_SH2_STAT5 479 482 PF00017 0.317
LIG_SH2_STAT5 602 605 PF00017 0.367
LIG_SH2_STAT5 614 617 PF00017 0.279
LIG_SH2_STAT5 63 66 PF00017 0.439
LIG_SH2_STAT5 74 77 PF00017 0.350
LIG_SH2_STAT5 809 812 PF00017 0.327
LIG_SH2_STAT5 910 913 PF00017 0.527
LIG_SH3_1 370 376 PF00018 0.323
LIG_SH3_1 444 450 PF00018 0.248
LIG_SH3_3 1111 1117 PF00018 0.431
LIG_SH3_3 1207 1213 PF00018 0.596
LIG_SH3_3 132 138 PF00018 0.316
LIG_SH3_3 370 376 PF00018 0.325
LIG_SH3_3 444 450 PF00018 0.248
LIG_SH3_3 567 573 PF00018 0.383
LIG_SH3_3 582 588 PF00018 0.348
LIG_SH3_3 855 861 PF00018 0.367
LIG_SH3_3 863 869 PF00018 0.388
LIG_SUMO_SIM_anti_2 1356 1364 PF11976 0.592
LIG_SUMO_SIM_anti_2 156 162 PF11976 0.360
LIG_SUMO_SIM_anti_2 566 571 PF11976 0.439
LIG_SUMO_SIM_anti_2 845 851 PF11976 0.427
LIG_SUMO_SIM_anti_2 926 935 PF11976 0.491
LIG_SUMO_SIM_par_1 897 904 PF11976 0.428
LIG_TRAF2_1 1037 1040 PF00917 0.612
LIG_TRAF2_1 127 130 PF00917 0.400
LIG_TRAF2_1 57 60 PF00917 0.347
LIG_TRAF2_1 641 644 PF00917 0.222
LIG_TRFH_1 584 588 PF08558 0.277
LIG_TYR_ITIM 1061 1066 PF00017 0.466
LIG_TYR_ITIM 239 244 PF00017 0.486
LIG_TYR_ITIM 615 620 PF00017 0.429
LIG_UBA3_1 122 131 PF00899 0.427
LIG_WRC_WIRS_1 739 744 PF05994 0.563
LIG_WRC_WIRS_1 821 826 PF05994 0.482
LIG_WW_3 1212 1216 PF00397 0.622
MOD_CDK_SPxxK_3 880 887 PF00069 0.444
MOD_CK1_1 1170 1176 PF00069 0.473
MOD_CK1_1 1286 1292 PF00069 0.621
MOD_CK1_1 1325 1331 PF00069 0.681
MOD_CK1_1 1341 1347 PF00069 0.639
MOD_CK1_1 242 248 PF00069 0.409
MOD_CK1_1 311 317 PF00069 0.472
MOD_CK1_1 325 331 PF00069 0.610
MOD_CK1_1 477 483 PF00069 0.422
MOD_CK1_1 495 501 PF00069 0.393
MOD_CK1_1 563 569 PF00069 0.386
MOD_CK1_1 741 747 PF00069 0.494
MOD_CK1_1 794 800 PF00069 0.442
MOD_CK1_1 986 992 PF00069 0.490
MOD_CK2_1 1034 1040 PF00069 0.512
MOD_CK2_1 1100 1106 PF00069 0.347
MOD_CK2_1 1142 1148 PF00069 0.668
MOD_CK2_1 1152 1158 PF00069 0.619
MOD_CK2_1 1326 1332 PF00069 0.702
MOD_CK2_1 1341 1347 PF00069 0.631
MOD_CK2_1 177 183 PF00069 0.521
MOD_CK2_1 379 385 PF00069 0.479
MOD_CK2_1 638 644 PF00069 0.367
MOD_CK2_1 748 754 PF00069 0.354
MOD_CK2_1 794 800 PF00069 0.439
MOD_CK2_1 829 835 PF00069 0.424
MOD_CK2_1 842 848 PF00069 0.434
MOD_CK2_1 931 937 PF00069 0.337
MOD_Cter_Amidation 1136 1139 PF01082 0.512
MOD_GlcNHglycan 1012 1015 PF01048 0.487
MOD_GlcNHglycan 1161 1164 PF01048 0.560
MOD_GlcNHglycan 1285 1288 PF01048 0.642
MOD_GlcNHglycan 1295 1298 PF01048 0.550
MOD_GlcNHglycan 1340 1343 PF01048 0.445
MOD_GlcNHglycan 1351 1355 PF01048 0.500
MOD_GlcNHglycan 155 158 PF01048 0.489
MOD_GlcNHglycan 167 170 PF01048 0.361
MOD_GlcNHglycan 288 291 PF01048 0.510
MOD_GlcNHglycan 310 313 PF01048 0.496
MOD_GlcNHglycan 324 327 PF01048 0.643
MOD_GlcNHglycan 350 354 PF01048 0.319
MOD_GlcNHglycan 402 405 PF01048 0.485
MOD_GlcNHglycan 44 47 PF01048 0.428
MOD_GlcNHglycan 466 469 PF01048 0.495
MOD_GlcNHglycan 640 643 PF01048 0.382
MOD_GlcNHglycan 985 988 PF01048 0.433
MOD_GSK3_1 1030 1037 PF00069 0.494
MOD_GSK3_1 1152 1159 PF00069 0.532
MOD_GSK3_1 1166 1173 PF00069 0.569
MOD_GSK3_1 1213 1220 PF00069 0.598
MOD_GSK3_1 1282 1289 PF00069 0.654
MOD_GSK3_1 1308 1315 PF00069 0.629
MOD_GSK3_1 1322 1329 PF00069 0.712
MOD_GSK3_1 1341 1348 PF00069 0.668
MOD_GSK3_1 165 172 PF00069 0.393
MOD_GSK3_1 173 180 PF00069 0.465
MOD_GSK3_1 235 242 PF00069 0.408
MOD_GSK3_1 280 287 PF00069 0.475
MOD_GSK3_1 322 329 PF00069 0.616
MOD_GSK3_1 375 382 PF00069 0.601
MOD_GSK3_1 407 414 PF00069 0.366
MOD_GSK3_1 464 471 PF00069 0.535
MOD_GSK3_1 477 484 PF00069 0.329
MOD_GSK3_1 488 495 PF00069 0.400
MOD_GSK3_1 667 674 PF00069 0.443
MOD_GSK3_1 68 75 PF00069 0.387
MOD_GSK3_1 746 753 PF00069 0.407
MOD_GSK3_1 794 801 PF00069 0.437
MOD_GSK3_1 813 820 PF00069 0.340
MOD_GSK3_1 829 836 PF00069 0.354
MOD_GSK3_1 861 868 PF00069 0.504
MOD_GSK3_1 927 934 PF00069 0.354
MOD_GSK3_1 972 979 PF00069 0.345
MOD_N-GLC_1 1308 1313 PF02516 0.655
MOD_N-GLC_1 418 423 PF02516 0.394
MOD_N-GLC_1 474 479 PF02516 0.486
MOD_N-GLC_1 493 498 PF02516 0.533
MOD_N-GLC_1 563 568 PF02516 0.452
MOD_N-GLC_1 773 778 PF02516 0.422
MOD_NEK2_1 1167 1172 PF00069 0.513
MOD_NEK2_1 1183 1188 PF00069 0.310
MOD_NEK2_1 1308 1313 PF00069 0.727
MOD_NEK2_1 1338 1343 PF00069 0.660
MOD_NEK2_1 164 169 PF00069 0.451
MOD_NEK2_1 207 212 PF00069 0.444
MOD_NEK2_1 256 261 PF00069 0.358
MOD_NEK2_1 27 32 PF00069 0.512
MOD_NEK2_1 293 298 PF00069 0.314
MOD_NEK2_1 33 38 PF00069 0.406
MOD_NEK2_1 402 407 PF00069 0.389
MOD_NEK2_1 42 47 PF00069 0.303
MOD_NEK2_1 455 460 PF00069 0.477
MOD_NEK2_1 482 487 PF00069 0.304
MOD_NEK2_1 532 537 PF00069 0.405
MOD_NEK2_1 623 628 PF00069 0.361
MOD_NEK2_1 630 635 PF00069 0.454
MOD_NEK2_1 652 657 PF00069 0.359
MOD_NEK2_1 671 676 PF00069 0.278
MOD_NEK2_1 724 729 PF00069 0.362
MOD_NEK2_1 740 745 PF00069 0.311
MOD_NEK2_1 792 797 PF00069 0.403
MOD_NEK2_1 842 847 PF00069 0.307
MOD_NEK2_1 90 95 PF00069 0.340
MOD_NEK2_1 901 906 PF00069 0.314
MOD_NEK2_2 173 178 PF00069 0.496
MOD_PIKK_1 1237 1243 PF00454 0.610
MOD_PIKK_1 1317 1323 PF00454 0.478
MOD_PIKK_1 340 346 PF00454 0.443
MOD_PIKK_1 495 501 PF00454 0.401
MOD_PIKK_1 90 96 PF00454 0.245
MOD_PKA_1 1257 1263 PF00069 0.589
MOD_PKA_1 379 385 PF00069 0.605
MOD_PKA_2 1034 1040 PF00069 0.515
MOD_PKA_2 1257 1263 PF00069 0.462
MOD_PKA_2 1280 1286 PF00069 0.660
MOD_PKA_2 1312 1318 PF00069 0.725
MOD_PKA_2 1322 1328 PF00069 0.707
MOD_PKA_2 1338 1344 PF00069 0.654
MOD_PKA_2 1363 1369 PF00069 0.408
MOD_PKA_2 142 148 PF00069 0.470
MOD_PKA_2 207 213 PF00069 0.518
MOD_PKA_2 27 33 PF00069 0.492
MOD_PKA_2 285 291 PF00069 0.502
MOD_PKA_2 3 9 PF00069 0.577
MOD_PKA_2 419 425 PF00069 0.379
MOD_PKA_2 623 629 PF00069 0.408
MOD_PKA_2 724 730 PF00069 0.289
MOD_PKB_1 1215 1223 PF00069 0.664
MOD_PKB_1 377 385 PF00069 0.347
MOD_Plk_1 1095 1101 PF00069 0.366
MOD_Plk_1 1346 1352 PF00069 0.695
MOD_Plk_1 242 248 PF00069 0.406
MOD_Plk_1 418 424 PF00069 0.397
MOD_Plk_1 474 480 PF00069 0.451
MOD_Plk_1 482 488 PF00069 0.419
MOD_Plk_1 532 538 PF00069 0.491
MOD_Plk_1 563 569 PF00069 0.451
MOD_Plk_1 630 636 PF00069 0.457
MOD_Plk_1 715 721 PF00069 0.438
MOD_Plk_2-3 72 78 PF00069 0.275
MOD_Plk_2-3 750 756 PF00069 0.386
MOD_Plk_2-3 972 978 PF00069 0.336
MOD_Plk_4 1095 1101 PF00069 0.305
MOD_Plk_4 1110 1116 PF00069 0.298
MOD_Plk_4 173 179 PF00069 0.409
MOD_Plk_4 225 231 PF00069 0.440
MOD_Plk_4 293 299 PF00069 0.397
MOD_Plk_4 402 408 PF00069 0.537
MOD_Plk_4 474 480 PF00069 0.453
MOD_Plk_4 505 511 PF00069 0.409
MOD_Plk_4 542 548 PF00069 0.402
MOD_Plk_4 715 721 PF00069 0.456
MOD_Plk_4 775 781 PF00069 0.375
MOD_Plk_4 794 800 PF00069 0.332
MOD_Plk_4 903 909 PF00069 0.340
MOD_Plk_4 927 933 PF00069 0.336
MOD_Plk_4 976 982 PF00069 0.350
MOD_ProDKin_1 1073 1079 PF00069 0.398
MOD_ProDKin_1 326 332 PF00069 0.498
MOD_ProDKin_1 677 683 PF00069 0.426
MOD_ProDKin_1 773 779 PF00069 0.414
MOD_ProDKin_1 861 867 PF00069 0.483
MOD_ProDKin_1 880 886 PF00069 0.454
MOD_SUMO_rev_2 183 191 PF00179 0.503
MOD_SUMO_rev_2 72 82 PF00179 0.337
MOD_SUMO_rev_2 794 804 PF00179 0.487
TRG_DiLeu_BaEn_1 927 932 PF01217 0.467
TRG_DiLeu_BaEn_4 1039 1045 PF01217 0.374
TRG_DiLeu_BaLyEn_6 305 310 PF01217 0.481
TRG_DiLeu_LyEn_5 1200 1205 PF01217 0.536
TRG_ENDOCYTIC_2 1015 1018 PF00928 0.343
TRG_ENDOCYTIC_2 1041 1044 PF00928 0.326
TRG_ENDOCYTIC_2 1063 1066 PF00928 0.464
TRG_ENDOCYTIC_2 241 244 PF00928 0.480
TRG_ENDOCYTIC_2 306 309 PF00928 0.490
TRG_ENDOCYTIC_2 357 360 PF00928 0.468
TRG_ENDOCYTIC_2 479 482 PF00928 0.372
TRG_ENDOCYTIC_2 514 517 PF00928 0.447
TRG_ENDOCYTIC_2 602 605 PF00928 0.562
TRG_ENDOCYTIC_2 617 620 PF00928 0.464
TRG_ENDOCYTIC_2 721 724 PF00928 0.371
TRG_ENDOCYTIC_2 839 842 PF00928 0.478
TRG_ENDOCYTIC_2 910 913 PF00928 0.460
TRG_ER_diArg_1 1048 1051 PF00400 0.337
TRG_ER_diArg_1 1214 1217 PF00400 0.597
TRG_ER_diArg_1 1278 1281 PF00400 0.685
TRG_ER_diArg_1 1303 1306 PF00400 0.566
TRG_ER_diArg_1 201 203 PF00400 0.462
TRG_ER_diArg_1 376 379 PF00400 0.370
TRG_ER_diArg_1 873 876 PF00400 0.536
TRG_NES_CRM1_1 499 512 PF08389 0.352
TRG_Pf-PMV_PEXEL_1 959 963 PF00026 0.413

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P457 Leptomonas seymouri 26% 100%
A0A1X0P171 Trypanosomatidae 33% 100%
A0A3Q8IJB0 Leishmania donovani 55% 100%
A0A3R7M6J4 Trypanosoma rangeli 36% 100%
A0A3R7R8G4 Trypanosoma rangeli 30% 100%
A0A3S5H6Z8 Leishmania donovani 55% 100%
A0A3S7WU91 Leishmania donovani 56% 97%
A0A3S7WU94 Leishmania donovani 86% 100%
A0A3S7WU95 Leishmania donovani 54% 98%
A0A3S7XB85 Leishmania donovani 29% 98%
A4H8U6 Leishmania braziliensis 66% 100%
A4H8V5 Leishmania braziliensis 56% 100%
A4H8V7 Leishmania braziliensis 52% 100%
A4H8V8 Leishmania braziliensis 52% 98%
A4HPI4 Leishmania braziliensis 27% 98%
A4HX84 Leishmania infantum 86% 100%
A4HX85 Leishmania infantum 55% 98%
A4HX87 Leishmania infantum 57% 100%
A4HX88 Leishmania infantum 42% 100%
A4IDA6 Leishmania infantum 30% 98%
C9ZM79 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM80 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZM81 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM83 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM86 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZN26 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZN41 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN43 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZN44 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN45 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN46 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZNA5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZNA6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZNH3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZNT1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZPZ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZQ51 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZQ89 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZQ90 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZQ92 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZTS4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZTS5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZTS6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZUE6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZWQ5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZWU1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZWU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZWU3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWY7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZZQ4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A0U3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A0W7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A0X5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A1S1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
D0A5D2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5D5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5U0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
D0A5U1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
D0A7A0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A9R3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0AAV3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
E9AQY0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 56% 98%
E9AQY1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 77% 99%
E9AQY2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 53% 98%
E9AQY4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 55% 100%
E9ARD7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 80% 100%
E9AT96 Leishmania mexicana (strain MHOM/GT/2001/U1103) 28% 98%
Q25263 Leishmania donovani 54% 100%
Q26721 Trypanosoma brucei brucei 33% 100%
Q27675 Leishmania donovani 86% 100%
Q4QEH9 Leishmania major 56% 100%
Q4QEI0 Leishmania major 56% 100%
Q4QEI1 Leishmania major 57% 100%
Q4QEI2 Leishmania major 57% 100%
Q99279 Trypanosoma brucei brucei 30% 100%
Q99280 Trypanosoma brucei brucei 31% 100%
V5AYH7 Trypanosoma cruzi 34% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS