LeishMANIAdb
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ATP pyrophosphate-lyase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP pyrophosphate-lyase
Gene product:
receptor-type adenylate cyclase, putative
Species:
Leishmania major
UniProt:
Q4QEI2_LEIMA
TriTrypDb:
LmjF.17.0190 , LMJLV39_170006500 * , LMJLV39_170006600 * , LMJSD75_170006400
Length:
1414

Annotations

LeishMANIAdb annotations

Carries an ATP pyrophosphate-lyase domain on its cytoplasmic segment. Likely acts as a receptor for some unknown extracellular stimulus. Extremely expanded kinetoplastid protein family.. Expressed in the insect stage (promastigote) but not in the mammalian host stage of the parasite life cycle.. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. no yes: 54
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. yes yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 44, no: 27
NetGPI no yes: 0, no: 71
Cellular components
Term Name Level Count
GO:0016020 membrane 2 67
GO:0110165 cellular anatomical entity 1 72

Expansion

Sequence features

Q4QEI2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 72
GO:0006163 purine nucleotide metabolic process 5 72
GO:0006164 purine nucleotide biosynthetic process 6 72
GO:0006171 cAMP biosynthetic process 8 72
GO:0006725 cellular aromatic compound metabolic process 3 72
GO:0006753 nucleoside phosphate metabolic process 4 72
GO:0006793 phosphorus metabolic process 3 72
GO:0006796 phosphate-containing compound metabolic process 4 72
GO:0006807 nitrogen compound metabolic process 2 72
GO:0007165 signal transduction 2 72
GO:0008152 metabolic process 1 72
GO:0009058 biosynthetic process 2 72
GO:0009117 nucleotide metabolic process 5 72
GO:0009150 purine ribonucleotide metabolic process 6 72
GO:0009152 purine ribonucleotide biosynthetic process 7 72
GO:0009165 nucleotide biosynthetic process 6 72
GO:0009187 cyclic nucleotide metabolic process 6 72
GO:0009190 cyclic nucleotide biosynthetic process 7 72
GO:0009259 ribonucleotide metabolic process 5 72
GO:0009260 ribonucleotide biosynthetic process 6 72
GO:0009987 cellular process 1 72
GO:0018130 heterocycle biosynthetic process 4 72
GO:0019438 aromatic compound biosynthetic process 4 72
GO:0019637 organophosphate metabolic process 3 72
GO:0019693 ribose phosphate metabolic process 4 72
GO:0034641 cellular nitrogen compound metabolic process 3 72
GO:0034654 nucleobase-containing compound biosynthetic process 4 72
GO:0035556 intracellular signal transduction 3 72
GO:0044237 cellular metabolic process 2 72
GO:0044238 primary metabolic process 2 72
GO:0044249 cellular biosynthetic process 3 72
GO:0044271 cellular nitrogen compound biosynthetic process 4 72
GO:0044281 small molecule metabolic process 2 72
GO:0046058 cAMP metabolic process 7 72
GO:0046390 ribose phosphate biosynthetic process 5 72
GO:0046483 heterocycle metabolic process 3 72
GO:0050789 regulation of biological process 2 72
GO:0050794 regulation of cellular process 3 72
GO:0052652 cyclic purine nucleotide metabolic process 6 72
GO:0055086 nucleobase-containing small molecule metabolic process 3 72
GO:0065007 biological regulation 1 72
GO:0071704 organic substance metabolic process 2 72
GO:0072521 purine-containing compound metabolic process 4 72
GO:0072522 purine-containing compound biosynthetic process 5 72
GO:0090407 organophosphate biosynthetic process 4 72
GO:1901135 carbohydrate derivative metabolic process 3 72
GO:1901137 carbohydrate derivative biosynthetic process 4 72
GO:1901293 nucleoside phosphate biosynthetic process 5 72
GO:1901360 organic cyclic compound metabolic process 3 72
GO:1901362 organic cyclic compound biosynthetic process 4 72
GO:1901564 organonitrogen compound metabolic process 3 72
GO:1901566 organonitrogen compound biosynthetic process 4 72
GO:1901576 organic substance biosynthetic process 3 72
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 62
GO:0016829 lyase activity 2 62

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1031 1035 PF00656 0.556
CLV_C14_Caspase3-7 182 186 PF00656 0.386
CLV_C14_Caspase3-7 396 400 PF00656 0.475
CLV_C14_Caspase3-7 93 97 PF00656 0.392
CLV_C14_Caspase3-7 997 1001 PF00656 0.488
CLV_MEL_PAP_1 1070 1076 PF00089 0.281
CLV_MEL_PAP_1 19 25 PF00089 0.231
CLV_NRD_NRD_1 1160 1162 PF00675 0.424
CLV_NRD_NRD_1 1328 1330 PF00675 0.517
CLV_NRD_NRD_1 1368 1370 PF00675 0.600
CLV_NRD_NRD_1 1398 1400 PF00675 0.360
CLV_NRD_NRD_1 219 221 PF00675 0.593
CLV_NRD_NRD_1 41 43 PF00675 0.355
CLV_NRD_NRD_1 440 442 PF00675 0.480
CLV_NRD_NRD_1 538 540 PF00675 0.588
CLV_NRD_NRD_1 897 899 PF00675 0.548
CLV_PCSK_FUR_1 217 221 PF00082 0.591
CLV_PCSK_KEX2_1 1160 1162 PF00082 0.424
CLV_PCSK_KEX2_1 1328 1330 PF00082 0.514
CLV_PCSK_KEX2_1 1368 1370 PF00082 0.432
CLV_PCSK_KEX2_1 1397 1399 PF00082 0.351
CLV_PCSK_KEX2_1 219 221 PF00082 0.593
CLV_PCSK_KEX2_1 29 31 PF00082 0.404
CLV_PCSK_KEX2_1 41 43 PF00082 0.332
CLV_PCSK_PC1ET2_1 29 31 PF00082 0.459
CLV_PCSK_SKI1_1 1022 1026 PF00082 0.282
CLV_PCSK_SKI1_1 1257 1261 PF00082 0.452
CLV_PCSK_SKI1_1 220 224 PF00082 0.592
CLV_PCSK_SKI1_1 518 522 PF00082 0.567
CLV_PCSK_SKI1_1 645 649 PF00082 0.498
CLV_PCSK_SKI1_1 667 671 PF00082 0.521
CLV_PCSK_SKI1_1 759 763 PF00082 0.521
CLV_PCSK_SKI1_1 802 806 PF00082 0.576
CLV_PCSK_SKI1_1 95 99 PF00082 0.643
CLV_PCSK_SKI1_1 984 988 PF00082 0.226
DEG_APCC_DBOX_1 1328 1336 PF00400 0.722
DEG_APCC_DBOX_1 40 48 PF00400 0.586
DEG_APCC_DBOX_1 801 809 PF00400 0.292
DEG_APCC_DBOX_1 897 905 PF00400 0.346
DEG_APCC_KENBOX_2 619 623 PF00400 0.221
DEG_COP1_1 676 685 PF00400 0.246
DEG_MDM2_SWIB_1 495 502 PF02201 0.192
DEG_ODPH_VHL_1 178 189 PF01847 0.203
DEG_ODPH_VHL_1 700 711 PF01847 0.231
DEG_SCF_FBW7_2 888 894 PF00400 0.511
DEG_SPOP_SBC_1 159 163 PF00917 0.249
DEG_SPOP_SBC_1 302 306 PF00917 0.425
DOC_CDC14_PxL_1 143 151 PF14671 0.427
DOC_CDC14_PxL_1 532 540 PF14671 0.232
DOC_CDC14_PxL_1 777 785 PF14671 0.219
DOC_CKS1_1 888 893 PF01111 0.449
DOC_CYCLIN_yCln2_LP_2 248 254 PF00134 0.338
DOC_CYCLIN_yCln2_LP_2 521 527 PF00134 0.375
DOC_MAPK_gen_1 1068 1076 PF00069 0.509
DOC_MAPK_gen_1 1303 1312 PF00069 0.728
DOC_MAPK_gen_1 1344 1350 PF00069 0.510
DOC_MAPK_gen_1 217 226 PF00069 0.300
DOC_MAPK_gen_1 29 37 PF00069 0.625
DOC_MAPK_gen_1 41 51 PF00069 0.593
DOC_MAPK_gen_1 95 104 PF00069 0.443
DOC_MAPK_HePTP_8 520 532 PF00069 0.388
DOC_MAPK_MEF2A_6 1068 1076 PF00069 0.437
DOC_MAPK_MEF2A_6 42 51 PF00069 0.510
DOC_MAPK_MEF2A_6 523 532 PF00069 0.418
DOC_MAPK_MEF2A_6 725 732 PF00069 0.270
DOC_MAPK_MEF2A_6 802 809 PF00069 0.317
DOC_MAPK_MEF2A_6 95 104 PF00069 0.440
DOC_MAPK_RevD_3 1147 1161 PF00069 0.543
DOC_MAPK_RevD_3 205 220 PF00069 0.251
DOC_PP1_RVXF_1 555 561 PF00149 0.311
DOC_PP1_RVXF_1 702 708 PF00149 0.254
DOC_PP1_RVXF_1 757 764 PF00149 0.304
DOC_PP2B_LxvP_1 248 251 PF13499 0.291
DOC_PP4_FxxP_1 156 159 PF00568 0.365
DOC_PP4_FxxP_1 177 180 PF00568 0.437
DOC_PP4_FxxP_1 611 614 PF00568 0.268
DOC_PP4_FxxP_1 625 628 PF00568 0.362
DOC_PP4_FxxP_1 680 683 PF00568 0.457
DOC_PP4_FxxP_1 820 823 PF00568 0.244
DOC_USP7_MATH_1 1005 1009 PF00917 0.560
DOC_USP7_MATH_1 1032 1036 PF00917 0.605
DOC_USP7_MATH_1 1259 1263 PF00917 0.679
DOC_USP7_MATH_1 1273 1277 PF00917 0.653
DOC_USP7_MATH_1 1304 1308 PF00917 0.688
DOC_USP7_MATH_1 1316 1320 PF00917 0.690
DOC_USP7_MATH_1 1364 1368 PF00917 0.610
DOC_USP7_MATH_1 1379 1383 PF00917 0.550
DOC_USP7_MATH_1 159 163 PF00917 0.429
DOC_USP7_MATH_1 302 306 PF00917 0.423
DOC_USP7_MATH_1 395 399 PF00917 0.355
DOC_USP7_MATH_1 468 472 PF00917 0.391
DOC_USP7_MATH_1 68 72 PF00917 0.367
DOC_USP7_MATH_1 689 693 PF00917 0.477
DOC_USP7_MATH_1 776 780 PF00917 0.290
DOC_USP7_UBL2_3 383 387 PF12436 0.462
DOC_USP7_UBL2_3 73 77 PF12436 0.313
DOC_USP7_UBL2_3 899 903 PF12436 0.510
DOC_WW_Pin1_4 330 335 PF00397 0.399
DOC_WW_Pin1_4 605 610 PF00397 0.323
DOC_WW_Pin1_4 770 775 PF00397 0.439
DOC_WW_Pin1_4 794 799 PF00397 0.335
DOC_WW_Pin1_4 884 889 PF00397 0.415
LIG_14-3-3_CanoR_1 1007 1015 PF00244 0.597
LIG_14-3-3_CanoR_1 1057 1063 PF00244 0.615
LIG_14-3-3_CanoR_1 1239 1246 PF00244 0.644
LIG_14-3-3_CanoR_1 1257 1262 PF00244 0.633
LIG_14-3-3_CanoR_1 1328 1333 PF00244 0.705
LIG_14-3-3_CanoR_1 1377 1382 PF00244 0.534
LIG_14-3-3_CanoR_1 217 226 PF00244 0.339
LIG_14-3-3_CanoR_1 22 26 PF00244 0.491
LIG_14-3-3_CanoR_1 303 310 PF00244 0.391
LIG_14-3-3_CanoR_1 357 367 PF00244 0.306
LIG_14-3-3_CanoR_1 36 44 PF00244 0.497
LIG_14-3-3_CanoR_1 441 445 PF00244 0.327
LIG_14-3-3_CanoR_1 551 560 PF00244 0.295
LIG_14-3-3_CanoR_1 645 654 PF00244 0.394
LIG_14-3-3_CanoR_1 693 697 PF00244 0.436
LIG_14-3-3_CanoR_1 744 752 PF00244 0.402
LIG_14-3-3_CanoR_1 759 764 PF00244 0.435
LIG_14-3-3_CanoR_1 845 849 PF00244 0.422
LIG_Actin_WH2_2 201 216 PF00022 0.235
LIG_Actin_WH2_2 523 541 PF00022 0.294
LIG_Actin_WH2_2 581 599 PF00022 0.214
LIG_AP2alpha_2 200 202 PF02296 0.215
LIG_APCC_ABBA_1 153 158 PF00400 0.436
LIG_BIR_II_1 1 5 PF00653 0.533
LIG_BIR_III_2 941 945 PF00653 0.654
LIG_BRCT_BRCA1_1 166 170 PF00533 0.425
LIG_BRCT_BRCA1_1 607 611 PF00533 0.218
LIG_BRCT_BRCA1_1 805 809 PF00533 0.393
LIG_deltaCOP1_diTrp_1 580 583 PF00928 0.201
LIG_eIF4E_1 780 786 PF01652 0.224
LIG_FHA_1 1019 1025 PF00498 0.554
LIG_FHA_1 1028 1034 PF00498 0.490
LIG_FHA_1 1053 1059 PF00498 0.499
LIG_FHA_1 1103 1109 PF00498 0.493
LIG_FHA_1 12 18 PF00498 0.568
LIG_FHA_1 159 165 PF00498 0.319
LIG_FHA_1 204 210 PF00498 0.313
LIG_FHA_1 359 365 PF00498 0.403
LIG_FHA_1 368 374 PF00498 0.436
LIG_FHA_1 412 418 PF00498 0.346
LIG_FHA_1 450 456 PF00498 0.365
LIG_FHA_1 677 683 PF00498 0.364
LIG_FHA_1 795 801 PF00498 0.367
LIG_FHA_1 84 90 PF00498 0.288
LIG_FHA_1 918 924 PF00498 0.392
LIG_FHA_2 1045 1051 PF00498 0.584
LIG_FHA_2 1165 1171 PF00498 0.731
LIG_FHA_2 1175 1181 PF00498 0.721
LIG_FHA_2 180 186 PF00498 0.358
LIG_FHA_2 195 201 PF00498 0.436
LIG_FHA_2 331 337 PF00498 0.412
LIG_FHA_2 349 355 PF00498 0.305
LIG_FHA_2 429 435 PF00498 0.396
LIG_FHA_2 692 698 PF00498 0.292
LIG_FHA_2 710 716 PF00498 0.334
LIG_FHA_2 852 858 PF00498 0.413
LIG_FHA_2 903 909 PF00498 0.450
LIG_FHA_2 91 97 PF00498 0.407
LIG_FHA_2 954 960 PF00498 0.488
LIG_FHA_2 995 1001 PF00498 0.491
LIG_GBD_Chelix_1 1015 1023 PF00786 0.397
LIG_GBD_Chelix_1 291 299 PF00786 0.507
LIG_GBD_Chelix_1 419 427 PF00786 0.507
LIG_GBD_Chelix_1 55 63 PF00786 0.438
LIG_Integrin_RGD_1 198 200 PF01839 0.424
LIG_IRF3_LxIS_1 601 608 PF10401 0.217
LIG_LIR_Apic_2 1049 1054 PF02991 0.479
LIG_LIR_Apic_2 174 180 PF02991 0.431
LIG_LIR_Apic_2 464 468 PF02991 0.357
LIG_LIR_Apic_2 608 614 PF02991 0.329
LIG_LIR_Apic_2 679 683 PF02991 0.461
LIG_LIR_Apic_2 817 823 PF02991 0.332
LIG_LIR_Gen_1 1060 1070 PF02991 0.542
LIG_LIR_Gen_1 1082 1092 PF02991 0.585
LIG_LIR_Gen_1 200 209 PF02991 0.413
LIG_LIR_Gen_1 221 231 PF02991 0.428
LIG_LIR_Gen_1 269 278 PF02991 0.336
LIG_LIR_Gen_1 529 538 PF02991 0.312
LIG_LIR_Gen_1 580 588 PF02991 0.332
LIG_LIR_Gen_1 621 630 PF02991 0.425
LIG_LIR_Gen_1 734 742 PF02991 0.245
LIG_LIR_Gen_1 746 756 PF02991 0.290
LIG_LIR_Gen_1 762 768 PF02991 0.355
LIG_LIR_Gen_1 952 963 PF02991 0.489
LIG_LIR_Nem_3 1034 1040 PF02991 0.490
LIG_LIR_Nem_3 1060 1066 PF02991 0.488
LIG_LIR_Nem_3 1082 1088 PF02991 0.507
LIG_LIR_Nem_3 1089 1095 PF02991 0.467
LIG_LIR_Nem_3 1118 1124 PF02991 0.501
LIG_LIR_Nem_3 1208 1214 PF02991 0.630
LIG_LIR_Nem_3 144 149 PF02991 0.364
LIG_LIR_Nem_3 221 226 PF02991 0.429
LIG_LIR_Nem_3 233 239 PF02991 0.316
LIG_LIR_Nem_3 529 535 PF02991 0.345
LIG_LIR_Nem_3 580 586 PF02991 0.256
LIG_LIR_Nem_3 621 626 PF02991 0.406
LIG_LIR_Nem_3 633 638 PF02991 0.347
LIG_LIR_Nem_3 734 738 PF02991 0.285
LIG_LIR_Nem_3 741 745 PF02991 0.307
LIG_LIR_Nem_3 746 752 PF02991 0.325
LIG_LIR_Nem_3 762 766 PF02991 0.349
LIG_LIR_Nem_3 778 783 PF02991 0.284
LIG_LIR_Nem_3 858 864 PF02991 0.443
LIG_LIR_Nem_3 952 958 PF02991 0.489
LIG_LIR_Nem_3 962 968 PF02991 0.591
LIG_LYPXL_yS_3 146 149 PF13949 0.293
LIG_LYPXL_yS_3 780 783 PF13949 0.224
LIG_MYND_3 627 631 PF01753 0.356
LIG_NRBOX 600 606 PF00104 0.213
LIG_NRBOX 800 806 PF00104 0.213
LIG_PCNA_yPIPBox_3 416 426 PF02747 0.432
LIG_PCNA_yPIPBox_3 903 917 PF02747 0.296
LIG_PDZ_Class_3 1409 1414 PF00595 0.587
LIG_Pex14_2 177 181 PF04695 0.426
LIG_Pex14_2 495 499 PF04695 0.194
LIG_PTB_Apo_2 75 82 PF02174 0.406
LIG_PTB_Apo_2 784 791 PF02174 0.223
LIG_PTB_Phospho_1 75 81 PF10480 0.413
LIG_SH2_CRK 236 240 PF00017 0.356
LIG_SH2_CRK 254 258 PF00017 0.432
LIG_SH2_CRK 465 469 PF00017 0.355
LIG_SH2_CRK 742 746 PF00017 0.429
LIG_SH2_GRB2like 515 518 PF00017 0.271
LIG_SH2_NCK_1 1085 1089 PF00017 0.579
LIG_SH2_NCK_1 254 258 PF00017 0.444
LIG_SH2_PTP2 1051 1054 PF00017 0.525
LIG_SH2_SRC 1051 1054 PF00017 0.537
LIG_SH2_SRC 1085 1088 PF00017 0.579
LIG_SH2_SRC 454 457 PF00017 0.392
LIG_SH2_STAP1 1063 1067 PF00017 0.543
LIG_SH2_STAP1 324 328 PF00017 0.420
LIG_SH2_STAP1 509 513 PF00017 0.318
LIG_SH2_STAP1 586 590 PF00017 0.334
LIG_SH2_STAP1 839 843 PF00017 0.380
LIG_SH2_STAT3 481 484 PF00017 0.416
LIG_SH2_STAT5 1051 1054 PF00017 0.470
LIG_SH2_STAT5 1246 1249 PF00017 0.616
LIG_SH2_STAT5 195 198 PF00017 0.334
LIG_SH2_STAT5 225 228 PF00017 0.299
LIG_SH2_STAT5 254 257 PF00017 0.425
LIG_SH2_STAT5 308 311 PF00017 0.305
LIG_SH2_STAT5 454 457 PF00017 0.291
LIG_SH2_STAT5 475 478 PF00017 0.385
LIG_SH2_STAT5 481 484 PF00017 0.379
LIG_SH2_STAT5 515 518 PF00017 0.300
LIG_SH2_STAT5 623 626 PF00017 0.342
LIG_SH2_STAT5 635 638 PF00017 0.291
LIG_SH2_STAT5 81 84 PF00017 0.448
LIG_SH3_3 1229 1235 PF00018 0.593
LIG_SH3_3 1385 1391 PF00018 0.522
LIG_SH3_3 149 155 PF00018 0.321
LIG_SH3_3 497 503 PF00018 0.333
LIG_SH3_3 588 594 PF00018 0.369
LIG_SH3_3 603 609 PF00018 0.325
LIG_SH3_3 679 685 PF00018 0.393
LIG_SH3_3 877 883 PF00018 0.385
LIG_SH3_3 885 891 PF00018 0.404
LIG_Sin3_3 1186 1193 PF02671 0.511
LIG_SUMO_SIM_anti_2 133 140 PF11976 0.430
LIG_SUMO_SIM_anti_2 1384 1389 PF11976 0.537
LIG_SUMO_SIM_anti_2 50 56 PF11976 0.398
LIG_SUMO_SIM_anti_2 587 592 PF11976 0.424
LIG_SUMO_SIM_anti_2 602 608 PF11976 0.253
LIG_SUMO_SIM_anti_2 803 809 PF11976 0.252
LIG_SUMO_SIM_anti_2 920 925 PF11976 0.384
LIG_SUMO_SIM_anti_2 948 957 PF11976 0.491
LIG_SUMO_SIM_par_1 203 210 PF11976 0.252
LIG_SUMO_SIM_par_1 238 245 PF11976 0.247
LIG_SUMO_SIM_par_1 45 50 PF11976 0.438
LIG_SUMO_SIM_par_1 602 608 PF11976 0.264
LIG_SUMO_SIM_par_1 729 734 PF11976 0.385
LIG_TRAF2_1 1059 1062 PF00917 0.610
LIG_TRAF2_1 1370 1373 PF00917 0.595
LIG_TRAF2_1 431 434 PF00917 0.442
LIG_TRAF2_1 825 828 PF00917 0.345
LIG_TRFH_1 87 91 PF08558 0.273
LIG_TYR_ITIM 1083 1088 PF00017 0.465
LIG_TYR_ITIM 636 641 PF00017 0.450
LIG_UBA3_1 208 214 PF00899 0.542
LIG_UBA3_1 490 496 PF00899 0.501
LIG_WRC_WIRS_1 243 248 PF05994 0.263
LIG_WRC_WIRS_1 404 409 PF05994 0.293
LIG_WRC_WIRS_1 719 724 PF05994 0.460
LIG_WRC_WIRS_1 732 737 PF05994 0.312
LIG_WRC_WIRS_1 760 765 PF05994 0.567
LIG_WW_3 1234 1238 PF00397 0.620
MOD_CK1_1 1008 1014 PF00069 0.489
MOD_CK1_1 1192 1198 PF00069 0.470
MOD_CK1_1 1296 1302 PF00069 0.565
MOD_CK1_1 1349 1355 PF00069 0.601
MOD_CK1_1 241 247 PF00069 0.397
MOD_CK1_1 341 347 PF00069 0.618
MOD_CK1_1 397 403 PF00069 0.593
MOD_CK1_1 639 645 PF00069 0.351
MOD_CK1_1 646 652 PF00069 0.349
MOD_CK1_1 691 697 PF00069 0.544
MOD_CK1_1 721 727 PF00069 0.434
MOD_CK1_1 770 776 PF00069 0.497
MOD_CK1_1 887 893 PF00069 0.639
MOD_CK2_1 1056 1062 PF00069 0.510
MOD_CK2_1 1122 1128 PF00069 0.347
MOD_CK2_1 1164 1170 PF00069 0.663
MOD_CK2_1 1174 1180 PF00069 0.660
MOD_CK2_1 1398 1404 PF00069 0.467
MOD_CK2_1 346 352 PF00069 0.514
MOD_CK2_1 428 434 PF00069 0.413
MOD_CK2_1 468 474 PF00069 0.464
MOD_CK2_1 691 697 PF00069 0.408
MOD_CK2_1 772 778 PF00069 0.317
MOD_CK2_1 822 828 PF00069 0.465
MOD_CK2_1 851 857 PF00069 0.418
MOD_CK2_1 902 908 PF00069 0.620
MOD_CK2_1 953 959 PF00069 0.337
MOD_Cter_Amidation 1158 1161 PF01082 0.518
MOD_GlcNHglycan 1007 1010 PF01048 0.432
MOD_GlcNHglycan 1034 1037 PF01048 0.486
MOD_GlcNHglycan 105 108 PF01048 0.445
MOD_GlcNHglycan 110 113 PF01048 0.473
MOD_GlcNHglycan 116 119 PF01048 0.460
MOD_GlcNHglycan 1183 1186 PF01048 0.566
MOD_GlcNHglycan 1191 1194 PF01048 0.461
MOD_GlcNHglycan 1275 1278 PF01048 0.491
MOD_GlcNHglycan 1284 1287 PF01048 0.339
MOD_GlcNHglycan 1306 1309 PF01048 0.659
MOD_GlcNHglycan 1317 1321 PF01048 0.637
MOD_GlcNHglycan 1377 1380 PF01048 0.527
MOD_GlcNHglycan 305 308 PF01048 0.478
MOD_GlcNHglycan 341 344 PF01048 0.625
MOD_GlcNHglycan 37 40 PF01048 0.476
MOD_GlcNHglycan 399 402 PF01048 0.604
MOD_GlcNHglycan 423 426 PF01048 0.485
MOD_GlcNHglycan 510 514 PF01048 0.379
MOD_GlcNHglycan 560 563 PF01048 0.415
MOD_GlcNHglycan 600 604 PF01048 0.441
MOD_GlcNHglycan 69 73 PF01048 0.478
MOD_GlcNHglycan 774 777 PF01048 0.394
MOD_GlcNHglycan 792 795 PF01048 0.298
MOD_GSK3_1 1052 1059 PF00069 0.492
MOD_GSK3_1 108 115 PF00069 0.382
MOD_GSK3_1 1174 1181 PF00069 0.526
MOD_GSK3_1 1188 1195 PF00069 0.556
MOD_GSK3_1 1235 1242 PF00069 0.593
MOD_GSK3_1 1312 1319 PF00069 0.690
MOD_GSK3_1 1335 1342 PF00069 0.650
MOD_GSK3_1 1360 1367 PF00069 0.702
MOD_GSK3_1 1373 1380 PF00069 0.713
MOD_GSK3_1 160 167 PF00069 0.423
MOD_GSK3_1 17 24 PF00069 0.476
MOD_GSK3_1 2 9 PF00069 0.313
MOD_GSK3_1 203 210 PF00069 0.516
MOD_GSK3_1 238 245 PF00069 0.397
MOD_GSK3_1 252 259 PF00069 0.423
MOD_GSK3_1 297 304 PF00069 0.457
MOD_GSK3_1 338 345 PF00069 0.606
MOD_GSK3_1 393 400 PF00069 0.602
MOD_GSK3_1 526 533 PF00069 0.389
MOD_GSK3_1 595 602 PF00069 0.340
MOD_GSK3_1 636 643 PF00069 0.376
MOD_GSK3_1 661 668 PF00069 0.417
MOD_GSK3_1 688 695 PF00069 0.530
MOD_GSK3_1 772 779 PF00069 0.371
MOD_GSK3_1 790 797 PF00069 0.460
MOD_GSK3_1 822 829 PF00069 0.455
MOD_GSK3_1 844 851 PF00069 0.485
MOD_GSK3_1 85 92 PF00069 0.398
MOD_GSK3_1 883 890 PF00069 0.528
MOD_GSK3_1 949 956 PF00069 0.354
MOD_GSK3_1 994 1001 PF00069 0.345
MOD_N-GLC_1 130 135 PF02516 0.331
MOD_N-GLC_1 170 175 PF02516 0.355
MOD_N-GLC_1 530 535 PF02516 0.476
MOD_N-GLC_1 568 573 PF02516 0.374
MOD_N-GLC_1 584 589 PF02516 0.445
MOD_N-GLC_1 83 88 PF02516 0.406
MOD_N-GLC_1 848 853 PF02516 0.432
MOD_NEK2_1 108 113 PF00069 0.356
MOD_NEK2_1 1189 1194 PF00069 0.493
MOD_NEK2_1 1205 1210 PF00069 0.289
MOD_NEK2_1 1282 1287 PF00069 0.443
MOD_NEK2_1 1321 1326 PF00069 0.726
MOD_NEK2_1 1327 1332 PF00069 0.680
MOD_NEK2_1 1335 1340 PF00069 0.683
MOD_NEK2_1 160 165 PF00069 0.501
MOD_NEK2_1 212 217 PF00069 0.427
MOD_NEK2_1 224 229 PF00069 0.468
MOD_NEK2_1 238 243 PF00069 0.400
MOD_NEK2_1 260 265 PF00069 0.408
MOD_NEK2_1 273 278 PF00069 0.371
MOD_NEK2_1 35 40 PF00069 0.510
MOD_NEK2_1 367 372 PF00069 0.517
MOD_NEK2_1 449 454 PF00069 0.242
MOD_NEK2_1 558 563 PF00069 0.386
MOD_NEK2_1 568 573 PF00069 0.341
MOD_NEK2_1 826 831 PF00069 0.386
MOD_NEK2_1 83 88 PF00069 0.361
MOD_NEK2_1 864 869 PF00069 0.311
MOD_NEK2_2 308 313 PF00069 0.280
MOD_NEK2_2 403 408 PF00069 0.293
MOD_PIKK_1 1259 1265 PF00454 0.635
MOD_PIKK_1 568 574 PF00454 0.389
MOD_PK_1 1377 1383 PF00069 0.426
MOD_PKA_1 1328 1334 PF00069 0.639
MOD_PKA_1 1344 1350 PF00069 0.634
MOD_PKA_1 1368 1374 PF00069 0.537
MOD_PKA_1 1398 1404 PF00069 0.438
MOD_PKA_1 266 272 PF00069 0.288
MOD_PKA_2 1056 1062 PF00069 0.514
MOD_PKA_2 1304 1310 PF00069 0.660
MOD_PKA_2 1321 1327 PF00069 0.619
MOD_PKA_2 1328 1334 PF00069 0.659
MOD_PKA_2 1368 1374 PF00069 0.774
MOD_PKA_2 1398 1404 PF00069 0.446
MOD_PKA_2 21 27 PF00069 0.425
MOD_PKA_2 218 224 PF00069 0.531
MOD_PKA_2 302 308 PF00069 0.471
MOD_PKA_2 35 41 PF00069 0.480
MOD_PKA_2 440 446 PF00069 0.370
MOD_PKA_2 486 492 PF00069 0.220
MOD_PKA_2 661 667 PF00069 0.403
MOD_PKA_2 692 698 PF00069 0.466
MOD_PKA_2 743 749 PF00069 0.287
MOD_PKA_2 844 850 PF00069 0.528
MOD_PKB_1 1237 1245 PF00069 0.659
MOD_PKB_1 1265 1273 PF00069 0.424
MOD_Plk_1 1117 1123 PF00069 0.368
MOD_Plk_1 203 209 PF00069 0.245
MOD_Plk_1 373 379 PF00069 0.399
MOD_Plk_1 428 434 PF00069 0.434
MOD_Plk_1 449 455 PF00069 0.384
MOD_Plk_1 568 574 PF00069 0.390
MOD_Plk_1 584 590 PF00069 0.435
MOD_Plk_1 639 645 PF00069 0.491
MOD_Plk_1 696 702 PF00069 0.322
MOD_Plk_1 83 89 PF00069 0.425
MOD_Plk_2-3 994 1000 PF00069 0.335
MOD_Plk_4 1117 1123 PF00069 0.301
MOD_Plk_4 1293 1299 PF00069 0.596
MOD_Plk_4 1398 1404 PF00069 0.438
MOD_Plk_4 145 151 PF00069 0.469
MOD_Plk_4 160 166 PF00069 0.430
MOD_Plk_4 203 209 PF00069 0.428
MOD_Plk_4 238 244 PF00069 0.434
MOD_Plk_4 373 379 PF00069 0.501
MOD_Plk_4 403 409 PF00069 0.548
MOD_Plk_4 47 53 PF00069 0.339
MOD_Plk_4 486 492 PF00069 0.404
MOD_Plk_4 718 724 PF00069 0.435
MOD_Plk_4 796 802 PF00069 0.364
MOD_Plk_4 803 809 PF00069 0.336
MOD_Plk_4 826 832 PF00069 0.336
MOD_Plk_4 949 955 PF00069 0.335
MOD_Plk_4 998 1004 PF00069 0.350
MOD_ProDKin_1 330 336 PF00069 0.496
MOD_ProDKin_1 605 611 PF00069 0.385
MOD_ProDKin_1 770 776 PF00069 0.546
MOD_ProDKin_1 794 800 PF00069 0.400
MOD_ProDKin_1 884 890 PF00069 0.515
MOD_SUMO_rev_2 233 239 PF00179 0.359
MOD_SUMO_rev_2 376 385 PF00179 0.580
MOD_SUMO_rev_2 434 443 PF00179 0.446
MOD_SUMO_rev_2 90 100 PF00179 0.337
TRG_DiLeu_BaEn_1 204 209 PF01217 0.279
TRG_DiLeu_BaEn_1 908 913 PF01217 0.273
TRG_DiLeu_BaEn_1 949 954 PF01217 0.466
TRG_DiLeu_BaEn_2 620 626 PF01217 0.392
TRG_DiLeu_BaEn_4 1061 1067 PF01217 0.379
TRG_DiLeu_BaLyEn_6 1287 1292 PF01217 0.538
TRG_DiLeu_LyEn_5 1222 1227 PF01217 0.538
TRG_DiLeu_LyEn_5 778 783 PF01217 0.238
TRG_ENDOCYTIC_2 1037 1040 PF00928 0.343
TRG_ENDOCYTIC_2 1063 1066 PF00928 0.326
TRG_ENDOCYTIC_2 1085 1088 PF00928 0.462
TRG_ENDOCYTIC_2 146 149 PF00928 0.502
TRG_ENDOCYTIC_2 236 239 PF00928 0.468
TRG_ENDOCYTIC_2 323 326 PF00928 0.475
TRG_ENDOCYTIC_2 623 626 PF00928 0.527
TRG_ENDOCYTIC_2 638 641 PF00928 0.484
TRG_ENDOCYTIC_2 742 745 PF00928 0.368
TRG_ENDOCYTIC_2 780 783 PF00928 0.515
TRG_ENDOCYTIC_2 861 864 PF00928 0.491
TRG_ER_diArg_1 1070 1073 PF00400 0.337
TRG_ER_diArg_1 1236 1239 PF00400 0.592
TRG_ER_diArg_1 1265 1268 PF00400 0.596
TRG_ER_diArg_1 1327 1329 PF00400 0.546
TRG_ER_diArg_1 1368 1370 PF00400 0.518
TRG_ER_diArg_1 1397 1399 PF00400 0.415
TRG_ER_diArg_1 216 219 PF00400 0.462
TRG_ER_diArg_1 40 42 PF00400 0.475
TRG_ER_diArg_1 895 898 PF00400 0.572
TRG_NLS_MonoExtC_3 265 271 PF00514 0.288
TRG_Pf-PMV_PEXEL_1 551 555 PF00026 0.353
TRG_Pf-PMV_PEXEL_1 981 985 PF00026 0.412

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P457 Leptomonas seymouri 26% 100%
A0A1X0P171 Trypanosomatidae 32% 100%
A0A3Q8IJB0 Leishmania donovani 63% 100%
A0A3R7R8G4 Trypanosoma rangeli 31% 100%
A0A3S5H6Z8 Leishmania donovani 63% 100%
A0A3S7WU91 Leishmania donovani 86% 100%
A0A3S7WU94 Leishmania donovani 56% 100%
A0A3S7WU95 Leishmania donovani 63% 100%
A0A3S7XB85 Leishmania donovani 28% 100%
A4H8U6 Leishmania braziliensis 55% 100%
A4H8V5 Leishmania braziliensis 68% 100%
A4H8V7 Leishmania braziliensis 60% 100%
A4H8V8 Leishmania braziliensis 58% 100%
A4HPI4 Leishmania braziliensis 28% 100%
A4HX84 Leishmania infantum 56% 100%
A4HX85 Leishmania infantum 63% 100%
A4HX87 Leishmania infantum 87% 100%
A4IDA6 Leishmania infantum 28% 100%
C9ZM79 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM80 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM81 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZM82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM83 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZM86 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZN26 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN41 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN43 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN44 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN45 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN46 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZNA5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZNA6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZNH3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZNT1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZPZ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZQ51 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZQ89 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZQ90 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZQ92 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZTS4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZTS5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZTS6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZUE6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWQ5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZWU1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZWU3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZWY7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZZQ4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A0U3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A0W7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A0X5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A1S1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5D2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5D5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5U0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A5U1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A7A0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A9R3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0AAV3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
E9AQY0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 81% 100%
E9AQY1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 58% 100%
E9AQY2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 61% 100%
E9AQY4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 61% 100%
E9ARD7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 55% 100%
Q25263 Leishmania donovani 62% 100%
Q26721 Trypanosoma brucei brucei 35% 100%
Q27675 Leishmania donovani 56% 100%
Q4QEH9 Leishmania major 68% 100%
Q4QEI0 Leishmania major 68% 100%
Q4QEI1 Leishmania major 67% 100%
Q4QEI3 Leishmania major 57% 100%
Q99279 Trypanosoma brucei brucei 30% 100%
Q99280 Trypanosoma brucei brucei 32% 100%
V5AYH7 Trypanosoma cruzi 34% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS