LeishMANIAdb
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ATP pyrophosphate-lyase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP pyrophosphate-lyase
Gene product:
receptor-type adenylate cyclase b
Species:
Leishmania major
UniProt:
Q4QEI1_LEIMA
TriTrypDb:
LmjF.17.0230 , LMJLV39_170006100 , LMJSD75_170006400
Length:
1264

Annotations

LeishMANIAdb annotations

Carries an ATP pyrophosphate-lyase domain on its cytoplasmic segment. Likely acts as a receptor for some unknown extracellular stimulus. Extremely expanded kinetoplastid protein family.. Expressed in the insect stage (promastigote) but not in the mammalian host stage of the parasite life cycle.. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. yes yes: 60
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 48, no: 32
NetGPI no yes: 0, no: 80
Cellular components
Term Name Level Count
GO:0016020 membrane 2 74
GO:0110165 cellular anatomical entity 1 80

Expansion

Sequence features

Q4QEI1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QEI1

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 77
GO:0006163 purine nucleotide metabolic process 5 77
GO:0006164 purine nucleotide biosynthetic process 6 77
GO:0006171 cAMP biosynthetic process 8 77
GO:0006725 cellular aromatic compound metabolic process 3 77
GO:0006753 nucleoside phosphate metabolic process 4 77
GO:0006793 phosphorus metabolic process 3 77
GO:0006796 phosphate-containing compound metabolic process 4 77
GO:0006807 nitrogen compound metabolic process 2 77
GO:0007165 signal transduction 2 77
GO:0008152 metabolic process 1 77
GO:0009058 biosynthetic process 2 77
GO:0009117 nucleotide metabolic process 5 77
GO:0009150 purine ribonucleotide metabolic process 6 77
GO:0009152 purine ribonucleotide biosynthetic process 7 77
GO:0009165 nucleotide biosynthetic process 6 77
GO:0009187 cyclic nucleotide metabolic process 6 77
GO:0009190 cyclic nucleotide biosynthetic process 7 77
GO:0009259 ribonucleotide metabolic process 5 77
GO:0009260 ribonucleotide biosynthetic process 6 77
GO:0009987 cellular process 1 77
GO:0018130 heterocycle biosynthetic process 4 77
GO:0019438 aromatic compound biosynthetic process 4 77
GO:0019637 organophosphate metabolic process 3 77
GO:0019693 ribose phosphate metabolic process 4 77
GO:0034641 cellular nitrogen compound metabolic process 3 77
GO:0034654 nucleobase-containing compound biosynthetic process 4 77
GO:0035556 intracellular signal transduction 3 77
GO:0044237 cellular metabolic process 2 77
GO:0044238 primary metabolic process 2 77
GO:0044249 cellular biosynthetic process 3 77
GO:0044271 cellular nitrogen compound biosynthetic process 4 77
GO:0044281 small molecule metabolic process 2 77
GO:0046058 cAMP metabolic process 7 77
GO:0046390 ribose phosphate biosynthetic process 5 77
GO:0046483 heterocycle metabolic process 3 77
GO:0050789 regulation of biological process 2 77
GO:0050794 regulation of cellular process 3 77
GO:0052652 cyclic purine nucleotide metabolic process 6 77
GO:0055086 nucleobase-containing small molecule metabolic process 3 77
GO:0065007 biological regulation 1 77
GO:0071704 organic substance metabolic process 2 77
GO:0072521 purine-containing compound metabolic process 4 77
GO:0072522 purine-containing compound biosynthetic process 5 77
GO:0090407 organophosphate biosynthetic process 4 77
GO:1901135 carbohydrate derivative metabolic process 3 77
GO:1901137 carbohydrate derivative biosynthetic process 4 77
GO:1901293 nucleoside phosphate biosynthetic process 5 77
GO:1901360 organic cyclic compound metabolic process 3 77
GO:1901362 organic cyclic compound biosynthetic process 4 77
GO:1901564 organonitrogen compound metabolic process 3 77
GO:1901566 organonitrogen compound biosynthetic process 4 77
GO:1901576 organic substance biosynthetic process 3 77
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 66
GO:0016829 lyase activity 2 66
GO:0004016 adenylate cyclase activity 3 2
GO:0009975 cyclase activity 2 2
GO:0016849 phosphorus-oxygen lyase activity 3 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1016 1020 PF00656 0.559
CLV_C14_Caspase3-7 634 638 PF00656 0.455
CLV_C14_Caspase3-7 982 986 PF00656 0.490
CLV_MEL_PAP_1 1055 1061 PF00089 0.282
CLV_NRD_NRD_1 1145 1147 PF00675 0.404
CLV_NRD_NRD_1 207 209 PF00675 0.631
CLV_NRD_NRD_1 659 661 PF00675 0.527
CLV_NRD_NRD_1 800 802 PF00675 0.642
CLV_NRD_NRD_1 882 884 PF00675 0.548
CLV_NRD_NRD_1 9 11 PF00675 0.776
CLV_PCSK_FUR_1 205 209 PF00082 0.631
CLV_PCSK_KEX2_1 1145 1147 PF00082 0.404
CLV_PCSK_KEX2_1 207 209 PF00082 0.631
CLV_PCSK_KEX2_1 800 802 PF00082 0.664
CLV_PCSK_KEX2_1 9 11 PF00082 0.787
CLV_PCSK_SKI1_1 1007 1011 PF00082 0.284
CLV_PCSK_SKI1_1 107 111 PF00082 0.666
CLV_PCSK_SKI1_1 1242 1246 PF00082 0.457
CLV_PCSK_SKI1_1 129 133 PF00082 0.589
CLV_PCSK_SKI1_1 208 212 PF00082 0.599
CLV_PCSK_SKI1_1 631 635 PF00082 0.560
CLV_PCSK_SKI1_1 745 749 PF00082 0.511
CLV_PCSK_SKI1_1 767 771 PF00082 0.632
CLV_PCSK_SKI1_1 83 87 PF00082 0.624
CLV_PCSK_SKI1_1 969 973 PF00082 0.223
CLV_Separin_Metazoa 604 608 PF03568 0.326
DEG_APCC_DBOX_1 882 890 PF00400 0.389
DEG_Nend_UBRbox_4 1 3 PF02207 0.722
DEG_SCF_FBW7_2 873 879 PF00400 0.465
DEG_SPOP_SBC_1 245 249 PF00917 0.290
DEG_SPOP_SBC_1 289 293 PF00917 0.459
DEG_SPOP_SBC_1 806 810 PF00917 0.550
DOC_CDC14_PxL_1 131 139 PF14671 0.320
DOC_CKS1_1 781 786 PF01111 0.358
DOC_CKS1_1 873 878 PF01111 0.409
DOC_CYCLIN_RxL_1 506 515 PF00134 0.306
DOC_CYCLIN_RxL_1 83 94 PF00134 0.428
DOC_CYCLIN_yCln2_LP_2 236 242 PF00134 0.376
DOC_CYCLIN_yCln2_LP_2 335 341 PF00134 0.318
DOC_CYCLIN_yCln2_LP_2 507 513 PF00134 0.422
DOC_CYCLIN_yCln2_LP_2 870 876 PF00134 0.413
DOC_MAPK_gen_1 1053 1061 PF00069 0.513
DOC_MAPK_gen_1 30 40 PF00069 0.717
DOC_MAPK_gen_1 688 697 PF00069 0.239
DOC_MAPK_gen_1 83 92 PF00069 0.431
DOC_MAPK_MEF2A_6 1053 1061 PF00069 0.440
DOC_MAPK_MEF2A_6 120 128 PF00069 0.386
DOC_MAPK_MEF2A_6 186 193 PF00069 0.351
DOC_MAPK_MEF2A_6 33 42 PF00069 0.588
DOC_MAPK_MEF2A_6 509 518 PF00069 0.441
DOC_MAPK_MEF2A_6 688 697 PF00069 0.430
DOC_MAPK_MEF2A_6 713 721 PF00069 0.296
DOC_MAPK_MEF2A_6 83 92 PF00069 0.431
DOC_MAPK_RevD_3 1132 1146 PF00069 0.532
DOC_PP1_RVXF_1 507 514 PF00149 0.303
DOC_PP1_RVXF_1 743 750 PF00149 0.303
DOC_PP2B_LxvP_1 236 239 PF13499 0.342
DOC_PP4_FxxP_1 165 168 PF00568 0.435
DOC_USP7_MATH_1 1017 1021 PF00917 0.606
DOC_USP7_MATH_1 1244 1248 PF00917 0.690
DOC_USP7_MATH_1 1258 1262 PF00917 0.745
DOC_USP7_MATH_1 151 155 PF00917 0.442
DOC_USP7_MATH_1 289 293 PF00917 0.455
DOC_USP7_MATH_1 675 679 PF00917 0.454
DOC_USP7_MATH_1 734 738 PF00917 0.440
DOC_USP7_MATH_1 777 781 PF00917 0.444
DOC_USP7_MATH_1 990 994 PF00917 0.554
DOC_USP7_UBL2_3 370 374 PF12436 0.435
DOC_USP7_UBL2_3 884 888 PF12436 0.573
DOC_WW_Pin1_4 1080 1085 PF00397 0.535
DOC_WW_Pin1_4 152 157 PF00397 0.409
DOC_WW_Pin1_4 317 322 PF00397 0.422
DOC_WW_Pin1_4 544 549 PF00397 0.454
DOC_WW_Pin1_4 557 562 PF00397 0.447
DOC_WW_Pin1_4 591 596 PF00397 0.357
DOC_WW_Pin1_4 60 65 PF00397 0.483
DOC_WW_Pin1_4 780 785 PF00397 0.368
DOC_WW_Pin1_4 835 840 PF00397 0.405
DOC_WW_Pin1_4 869 874 PF00397 0.376
LIG_14-3-3_CanoR_1 1042 1048 PF00244 0.616
LIG_14-3-3_CanoR_1 1224 1231 PF00244 0.667
LIG_14-3-3_CanoR_1 1242 1247 PF00244 0.649
LIG_14-3-3_CanoR_1 205 214 PF00244 0.360
LIG_14-3-3_CanoR_1 290 298 PF00244 0.402
LIG_14-3-3_CanoR_1 660 668 PF00244 0.377
LIG_14-3-3_CanoR_1 745 750 PF00244 0.428
LIG_14-3-3_CanoR_1 767 772 PF00244 0.437
LIG_14-3-3_CanoR_1 992 1000 PF00244 0.598
LIG_Actin_WH2_2 528 545 PF00022 0.255
LIG_APCC_ABBA_1 141 146 PF00400 0.435
LIG_APCC_ABBA_1 307 312 PF00400 0.303
LIG_APCC_ABBA_1 718 723 PF00400 0.303
LIG_BIR_III_2 926 930 PF00653 0.618
LIG_deltaCOP1_diTrp_1 217 222 PF00928 0.265
LIG_deltaCOP1_diTrp_1 79 89 PF00928 0.233
LIG_eIF4E_1 29 35 PF01652 0.667
LIG_FHA_1 1004 1010 PF00498 0.552
LIG_FHA_1 1013 1019 PF00498 0.487
LIG_FHA_1 1038 1044 PF00498 0.498
LIG_FHA_1 1088 1094 PF00498 0.495
LIG_FHA_1 304 310 PF00498 0.382
LIG_FHA_1 355 361 PF00498 0.449
LIG_FHA_1 44 50 PF00498 0.697
LIG_FHA_1 571 577 PF00498 0.372
LIG_FHA_1 654 660 PF00498 0.351
LIG_FHA_1 677 683 PF00498 0.415
LIG_FHA_1 712 718 PF00498 0.422
LIG_FHA_1 810 816 PF00498 0.419
LIG_FHA_1 821 827 PF00498 0.398
LIG_FHA_1 838 844 PF00498 0.532
LIG_FHA_1 903 909 PF00498 0.392
LIG_FHA_2 1030 1036 PF00498 0.586
LIG_FHA_2 1150 1156 PF00498 0.762
LIG_FHA_2 1160 1166 PF00498 0.795
LIG_FHA_2 253 259 PF00498 0.427
LIG_FHA_2 318 324 PF00498 0.424
LIG_FHA_2 415 421 PF00498 0.421
LIG_FHA_2 632 638 PF00498 0.474
LIG_FHA_2 696 702 PF00498 0.355
LIG_FHA_2 836 842 PF00498 0.519
LIG_FHA_2 888 894 PF00498 0.532
LIG_FHA_2 939 945 PF00498 0.489
LIG_FHA_2 980 986 PF00498 0.494
LIG_GBD_Chelix_1 1000 1008 PF00786 0.390
LIG_GBD_Chelix_1 278 286 PF00786 0.503
LIG_GBD_Chelix_1 405 413 PF00786 0.497
LIG_LIR_Apic_2 1034 1039 PF02991 0.479
LIG_LIR_Apic_2 292 298 PF02991 0.255
LIG_LIR_Apic_2 450 454 PF02991 0.372
LIG_LIR_Apic_2 665 671 PF02991 0.463
LIG_LIR_Gen_1 1045 1055 PF02991 0.545
LIG_LIR_Gen_1 1067 1077 PF02991 0.588
LIG_LIR_Gen_1 209 219 PF02991 0.449
LIG_LIR_Gen_1 255 265 PF02991 0.348
LIG_LIR_Gen_1 588 598 PF02991 0.412
LIG_LIR_Gen_1 748 754 PF02991 0.342
LIG_LIR_Gen_1 937 948 PF02991 0.490
LIG_LIR_Nem_3 1019 1025 PF02991 0.492
LIG_LIR_Nem_3 1045 1051 PF02991 0.492
LIG_LIR_Nem_3 1067 1073 PF02991 0.508
LIG_LIR_Nem_3 1074 1080 PF02991 0.469
LIG_LIR_Nem_3 1103 1109 PF02991 0.504
LIG_LIR_Nem_3 1193 1199 PF02991 0.674
LIG_LIR_Nem_3 133 137 PF02991 0.415
LIG_LIR_Nem_3 209 214 PF02991 0.422
LIG_LIR_Nem_3 217 222 PF02991 0.402
LIG_LIR_Nem_3 306 310 PF02991 0.364
LIG_LIR_Nem_3 588 593 PF02991 0.351
LIG_LIR_Nem_3 748 752 PF02991 0.332
LIG_LIR_Nem_3 937 943 PF02991 0.490
LIG_LIR_Nem_3 947 953 PF02991 0.593
LIG_LYPXL_yS_3 134 137 PF13949 0.326
LIG_MYND_3 613 617 PF01753 0.427
LIG_PCNA_yPIPBox_3 888 902 PF02747 0.389
LIG_Pex14_1 218 222 PF04695 0.264
LIG_Pex14_2 165 169 PF04695 0.427
LIG_PTB_Apo_2 388 395 PF02174 0.300
LIG_PTB_Apo_2 605 612 PF02174 0.462
LIG_PTB_Apo_2 69 76 PF02174 0.356
LIG_PTB_Phospho_1 605 611 PF10480 0.467
LIG_PTB_Phospho_1 69 75 PF10480 0.361
LIG_SH2_CRK 242 246 PF00017 0.465
LIG_SH2_CRK 451 455 PF00017 0.375
LIG_SH2_CRK 624 628 PF00017 0.437
LIG_SH2_CRK 668 672 PF00017 0.485
LIG_SH2_CRK 728 732 PF00017 0.434
LIG_SH2_GRB2like 389 392 PF00017 0.458
LIG_SH2_GRB2like 668 671 PF00017 0.481
LIG_SH2_GRB2like 846 849 PF00017 0.295
LIG_SH2_NCK_1 101 105 PF00017 0.446
LIG_SH2_NCK_1 1070 1074 PF00017 0.581
LIG_SH2_NCK_1 242 246 PF00017 0.475
LIG_SH2_NCK_1 668 672 PF00017 0.320
LIG_SH2_PTP2 1036 1039 PF00017 0.520
LIG_SH2_PTP2 295 298 PF00017 0.375
LIG_SH2_PTP2 609 612 PF00017 0.426
LIG_SH2_SRC 1036 1039 PF00017 0.533
LIG_SH2_SRC 1070 1073 PF00017 0.581
LIG_SH2_SRC 668 671 PF00017 0.464
LIG_SH2_STAP1 1048 1052 PF00017 0.546
LIG_SH2_STAP1 311 315 PF00017 0.442
LIG_SH2_STAP1 572 576 PF00017 0.387
LIG_SH2_STAP1 728 732 PF00017 0.275
LIG_SH2_STAT3 467 470 PF00017 0.425
LIG_SH2_STAT3 849 852 PF00017 0.322
LIG_SH2_STAT5 101 104 PF00017 0.416
LIG_SH2_STAT5 1036 1039 PF00017 0.469
LIG_SH2_STAT5 1231 1234 PF00017 0.616
LIG_SH2_STAT5 183 186 PF00017 0.325
LIG_SH2_STAT5 213 216 PF00017 0.331
LIG_SH2_STAT5 295 298 PF00017 0.309
LIG_SH2_STAT5 389 392 PF00017 0.407
LIG_SH2_STAT5 440 443 PF00017 0.313
LIG_SH2_STAT5 467 470 PF00017 0.391
LIG_SH2_STAT5 541 544 PF00017 0.391
LIG_SH2_STAT5 572 575 PF00017 0.476
LIG_SH2_STAT5 590 593 PF00017 0.445
LIG_SH2_STAT5 609 612 PF00017 0.346
LIG_SH2_STAT5 69 72 PF00017 0.391
LIG_SH2_STAT5 917 920 PF00017 0.658
LIG_SH3_3 1214 1220 PF00018 0.616
LIG_SH3_3 137 143 PF00018 0.314
LIG_SH3_3 516 522 PF00018 0.348
LIG_SH3_3 589 595 PF00018 0.369
LIG_SH3_3 61 67 PF00018 0.469
LIG_SH3_3 862 868 PF00018 0.373
LIG_SH3_3 870 876 PF00018 0.361
LIG_Sin3_3 1171 1178 PF02671 0.558
LIG_SUMO_SIM_anti_2 121 128 PF11976 0.444
LIG_SUMO_SIM_anti_2 226 233 PF11976 0.462
LIG_SUMO_SIM_anti_2 714 723 PF11976 0.345
LIG_SUMO_SIM_anti_2 905 910 PF11976 0.382
LIG_SUMO_SIM_anti_2 933 942 PF11976 0.490
LIG_SUMO_SIM_par_1 45 51 PF11976 0.650
LIG_SUMO_SIM_par_1 693 698 PF11976 0.394
LIG_SUMO_SIM_par_1 714 723 PF11976 0.399
LIG_SUMO_SIM_par_1 853 858 PF11976 0.438
LIG_TRAF2_1 1044 1047 PF00917 0.612
LIG_TYR_ITIM 1068 1073 PF00017 0.468
LIG_TYR_ITIM 622 627 PF00017 0.434
LIG_TYR_ITIM 726 731 PF00017 0.393
LIG_UBA3_1 193 198 PF00899 0.550
LIG_UBA3_1 538 543 PF00899 0.293
LIG_UBA3_1 620 626 PF00899 0.476
LIG_WRC_WIRS_1 219 224 PF05994 0.348
LIG_WRC_WIRS_1 297 302 PF05994 0.514
LIG_WRC_WIRS_1 746 751 PF05994 0.550
LIG_WW_3 1219 1223 PF00397 0.660
MOD_CDK_SPxxK_3 835 842 PF00069 0.450
MOD_CK1_1 1177 1183 PF00069 0.566
MOD_CK1_1 247 253 PF00069 0.495
MOD_CK1_1 328 334 PF00069 0.558
MOD_CK1_1 383 389 PF00069 0.596
MOD_CK1_1 491 497 PF00069 0.472
MOD_CK1_1 499 505 PF00069 0.438
MOD_CK1_1 635 641 PF00069 0.408
MOD_CK1_1 662 668 PF00069 0.413
MOD_CK1_1 678 684 PF00069 0.528
MOD_CK1_1 756 762 PF00069 0.541
MOD_CK1_1 78 84 PF00069 0.462
MOD_CK1_1 780 786 PF00069 0.423
MOD_CK1_1 805 811 PF00069 0.586
MOD_CK1_1 819 825 PF00069 0.375
MOD_CK1_1 872 878 PF00069 0.585
MOD_CK1_1 993 999 PF00069 0.490
MOD_CK2_1 1041 1047 PF00069 0.512
MOD_CK2_1 1107 1113 PF00069 0.350
MOD_CK2_1 1149 1155 PF00069 0.691
MOD_CK2_1 1159 1165 PF00069 0.709
MOD_CK2_1 151 157 PF00069 0.472
MOD_CK2_1 223 229 PF00069 0.506
MOD_CK2_1 414 420 PF00069 0.427
MOD_CK2_1 60 66 PF00069 0.684
MOD_CK2_1 887 893 PF00069 0.727
MOD_CK2_1 938 944 PF00069 0.338
MOD_Cter_Amidation 1143 1146 PF01082 0.522
MOD_GlcNHglycan 1019 1022 PF01048 0.489
MOD_GlcNHglycan 104 107 PF01048 0.430
MOD_GlcNHglycan 1168 1171 PF01048 0.628
MOD_GlcNHglycan 1176 1179 PF01048 0.549
MOD_GlcNHglycan 1260 1263 PF01048 0.627
MOD_GlcNHglycan 160 163 PF01048 0.527
MOD_GlcNHglycan 172 175 PF01048 0.366
MOD_GlcNHglycan 242 245 PF01048 0.477
MOD_GlcNHglycan 292 295 PF01048 0.516
MOD_GlcNHglycan 328 331 PF01048 0.551
MOD_GlcNHglycan 385 388 PF01048 0.590
MOD_GlcNHglycan 409 412 PF01048 0.477
MOD_GlcNHglycan 473 476 PF01048 0.508
MOD_GlcNHglycan 490 493 PF01048 0.482
MOD_GlcNHglycan 544 547 PF01048 0.546
MOD_GlcNHglycan 627 630 PF01048 0.477
MOD_GlcNHglycan 637 640 PF01048 0.448
MOD_GlcNHglycan 661 664 PF01048 0.506
MOD_GlcNHglycan 683 686 PF01048 0.471
MOD_GlcNHglycan 760 763 PF01048 0.611
MOD_GlcNHglycan 787 790 PF01048 0.463
MOD_GlcNHglycan 795 798 PF01048 0.483
MOD_GlcNHglycan 93 96 PF01048 0.415
MOD_GlcNHglycan 992 995 PF01048 0.435
MOD_GSK3_1 1037 1044 PF00069 0.495
MOD_GSK3_1 114 121 PF00069 0.463
MOD_GSK3_1 1159 1166 PF00069 0.632
MOD_GSK3_1 1173 1180 PF00069 0.646
MOD_GSK3_1 1220 1227 PF00069 0.649
MOD_GSK3_1 240 247 PF00069 0.470
MOD_GSK3_1 284 291 PF00069 0.470
MOD_GSK3_1 325 332 PF00069 0.537
MOD_GSK3_1 333 340 PF00069 0.531
MOD_GSK3_1 43 50 PF00069 0.702
MOD_GSK3_1 471 478 PF00069 0.538
MOD_GSK3_1 499 506 PF00069 0.459
MOD_GSK3_1 566 573 PF00069 0.495
MOD_GSK3_1 631 638 PF00069 0.456
MOD_GSK3_1 671 678 PF00069 0.482
MOD_GSK3_1 726 733 PF00069 0.512
MOD_GSK3_1 734 741 PF00069 0.525
MOD_GSK3_1 763 770 PF00069 0.446
MOD_GSK3_1 791 798 PF00069 0.511
MOD_GSK3_1 802 809 PF00069 0.587
MOD_GSK3_1 816 823 PF00069 0.460
MOD_GSK3_1 833 840 PF00069 0.612
MOD_GSK3_1 868 875 PF00069 0.486
MOD_GSK3_1 934 941 PF00069 0.354
MOD_GSK3_1 979 986 PF00069 0.348
MOD_N-GLC_1 252 257 PF02516 0.543
MOD_N-GLC_1 531 536 PF02516 0.527
MOD_N-GLC_1 554 559 PF02516 0.496
MOD_N-GLC_1 570 575 PF02516 0.557
MOD_N-GLC_1 60 65 PF02516 0.524
MOD_N-GLC_1 653 658 PF02516 0.481
MOD_NEK2_1 1174 1179 PF00069 0.588
MOD_NEK2_1 1190 1195 PF00069 0.376
MOD_NEK2_1 169 174 PF00069 0.463
MOD_NEK2_1 230 235 PF00069 0.517
MOD_NEK2_1 260 265 PF00069 0.384
MOD_NEK2_1 354 359 PF00069 0.519
MOD_NEK2_1 47 52 PF00069 0.551
MOD_NEK2_1 542 547 PF00069 0.502
MOD_NEK2_1 659 664 PF00069 0.385
MOD_NEK2_1 695 700 PF00069 0.493
MOD_NEK2_1 795 800 PF00069 0.421
MOD_NEK2_1 802 807 PF00069 0.538
MOD_PIKK_1 1244 1250 PF00454 0.660
MOD_PIKK_1 398 404 PF00454 0.459
MOD_PIKK_1 433 439 PF00454 0.522
MOD_PIKK_1 493 499 PF00454 0.500
MOD_PIKK_1 777 783 PF00454 0.537
MOD_PK_1 738 744 PF00069 0.351
MOD_PK_1 817 823 PF00069 0.346
MOD_PKA_2 1041 1047 PF00069 0.515
MOD_PKA_2 206 212 PF00069 0.553
MOD_PKA_2 289 295 PF00069 0.509
MOD_PKA_2 29 35 PF00069 0.719
MOD_PKA_2 659 665 PF00069 0.423
MOD_PKA_2 816 822 PF00069 0.575
MOD_PKB_1 1222 1230 PF00069 0.695
MOD_PKB_1 1250 1258 PF00069 0.489
MOD_Plk_1 1102 1108 PF00069 0.367
MOD_Plk_1 252 258 PF00069 0.475
MOD_Plk_1 502 508 PF00069 0.497
MOD_Plk_1 531 537 PF00069 0.512
MOD_Plk_1 631 637 PF00069 0.536
MOD_Plk_1 653 659 PF00069 0.431
MOD_Plk_1 711 717 PF00069 0.506
MOD_Plk_1 78 84 PF00069 0.431
MOD_Plk_1 817 823 PF00069 0.479
MOD_Plk_2-3 223 229 PF00069 0.514
MOD_Plk_2-3 632 638 PF00069 0.610
MOD_Plk_2-3 646 652 PF00069 0.509
MOD_Plk_2-3 979 985 PF00069 0.338
MOD_Plk_4 1102 1108 PF00069 0.310
MOD_Plk_4 133 139 PF00069 0.518
MOD_Plk_4 223 229 PF00069 0.488
MOD_Plk_4 360 366 PF00069 0.502
MOD_Plk_4 409 415 PF00069 0.526
MOD_Plk_4 512 518 PF00069 0.428
MOD_Plk_4 712 718 PF00069 0.491
MOD_Plk_4 727 733 PF00069 0.471
MOD_Plk_4 767 773 PF00069 0.485
MOD_Plk_4 934 940 PF00069 0.335
MOD_Plk_4 983 989 PF00069 0.352
MOD_ProDKin_1 1080 1086 PF00069 0.401
MOD_ProDKin_1 152 158 PF00069 0.497
MOD_ProDKin_1 317 323 PF00069 0.525
MOD_ProDKin_1 544 550 PF00069 0.560
MOD_ProDKin_1 557 563 PF00069 0.557
MOD_ProDKin_1 591 597 PF00069 0.432
MOD_ProDKin_1 60 66 PF00069 0.595
MOD_ProDKin_1 780 786 PF00069 0.444
MOD_ProDKin_1 835 841 PF00069 0.499
MOD_ProDKin_1 869 875 PF00069 0.461
MOD_SUMO_rev_2 217 227 PF00179 0.428
MOD_SUMO_rev_2 363 372 PF00179 0.553
MOD_SUMO_rev_2 707 715 PF00179 0.566
TRG_DiLeu_BaEn_1 223 228 PF01217 0.543
TRG_DiLeu_BaEn_1 66 71 PF01217 0.524
TRG_DiLeu_BaEn_1 893 898 PF01217 0.419
TRG_DiLeu_BaEn_1 934 939 PF01217 0.469
TRG_DiLeu_BaEn_2 179 185 PF01217 0.542
TRG_DiLeu_BaEn_2 616 622 PF01217 0.347
TRG_DiLeu_BaEn_3 711 717 PF01217 0.552
TRG_DiLeu_BaEn_4 1046 1052 PF01217 0.366
TRG_DiLeu_BaLyEn_6 30 35 PF01217 0.639
TRG_DiLeu_BaLyEn_6 519 524 PF01217 0.528
TRG_DiLeu_BaLyEn_6 764 769 PF01217 0.310
TRG_DiLeu_LyEn_5 1207 1212 PF01217 0.523
TRG_ENDOCYTIC_2 1022 1025 PF00928 0.346
TRG_ENDOCYTIC_2 1048 1051 PF00928 0.330
TRG_ENDOCYTIC_2 1070 1073 PF00928 0.466
TRG_ENDOCYTIC_2 134 137 PF00928 0.563
TRG_ENDOCYTIC_2 310 313 PF00928 0.498
TRG_ENDOCYTIC_2 590 593 PF00928 0.568
TRG_ENDOCYTIC_2 609 612 PF00928 0.533
TRG_ENDOCYTIC_2 624 627 PF00928 0.480
TRG_ENDOCYTIC_2 728 731 PF00928 0.400
TRG_ENDOCYTIC_2 917 920 PF00928 0.643
TRG_ER_diArg_1 1055 1058 PF00400 0.340
TRG_ER_diArg_1 1221 1224 PF00400 0.667
TRG_ER_diArg_1 1250 1253 PF00400 0.665
TRG_ER_diArg_1 204 207 PF00400 0.529
TRG_ER_diArg_1 688 691 PF00400 0.585
TRG_ER_diArg_1 799 801 PF00400 0.560
TRG_ER_diArg_1 8 10 PF00400 0.513
TRG_ER_diArg_1 880 883 PF00400 0.545
TRG_Pf-PMV_PEXEL_1 225 229 PF00026 0.320
TRG_Pf-PMV_PEXEL_1 800 804 PF00026 0.387
TRG_Pf-PMV_PEXEL_1 966 970 PF00026 0.415

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P457 Leptomonas seymouri 26% 95%
A0A1X0NPQ6 Trypanosomatidae 28% 100%
A0A1X0P171 Trypanosomatidae 33% 99%
A0A3Q8IJB0 Leishmania donovani 89% 95%
A0A3R7KBB6 Trypanosoma rangeli 28% 100%
A0A3R7M6J4 Trypanosoma rangeli 38% 100%
A0A3R7R8G4 Trypanosoma rangeli 31% 100%
A0A3S5H6Z8 Leishmania donovani 89% 95%
A0A3S7WU91 Leishmania donovani 64% 89%
A0A3S7WU94 Leishmania donovani 56% 92%
A0A3S7WU95 Leishmania donovani 83% 90%
A0A3S7XB85 Leishmania donovani 27% 90%
A4H8U6 Leishmania braziliensis 55% 97%
A4H8V5 Leishmania braziliensis 62% 100%
A4H8V7 Leishmania braziliensis 69% 100%
A4H8V8 Leishmania braziliensis 71% 90%
A4HPI4 Leishmania braziliensis 26% 90%
A4HX84 Leishmania infantum 56% 92%
A4HX85 Leishmania infantum 90% 90%
A4HX87 Leishmania infantum 64% 96%
A4HX88 Leishmania infantum 80% 100%
A4IDA6 Leishmania infantum 28% 90%
C9ZM79 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM80 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM81 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM83 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 98%
C9ZM86 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZN26 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 99%
C9ZN41 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN43 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN44 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN45 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZN46 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZNA5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZNA6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZNH3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 99%
C9ZNT1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZPZ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZQ51 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZQ89 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 99%
C9ZQ90 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZQ91 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 24% 100%
C9ZQ92 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZTS4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZTS5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZTS6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZUE6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZWQ5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWU1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 93%
C9ZWU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZWU3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZWY7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZZQ4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A0U3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A0W7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A0X5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A1S1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5D2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5D5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5U0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5U1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A7A0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
D0A9R3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0AAV3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
E8NHJ6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 49% 100%
E9AQY0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 64% 90%
E9AQY1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 56% 91%
E9AQY2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 79% 90%
E9AQY4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 83% 95%
E9ARD7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 55% 92%
E9AT96 Leishmania mexicana (strain MHOM/GT/2001/U1103) 26% 90%
Q25263 Leishmania donovani 89% 95%
Q26721 Trypanosoma brucei brucei 33% 100%
Q27675 Leishmania donovani 56% 92%
Q4Q1A1 Leishmania major 28% 100%
Q4QEH9 Leishmania major 99% 100%
Q4QEI0 Leishmania major 100% 100%
Q4QEI2 Leishmania major 67% 89%
Q4QEI3 Leishmania major 57% 92%
Q99279 Trypanosoma brucei brucei 29% 100%
Q99280 Trypanosoma brucei brucei 31% 100%
V5AYH7 Trypanosoma cruzi 33% 99%
V5B1C8 Trypanosoma cruzi 38% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS