Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QEA8_LEIMA

TriTrypDb:

LmjF.17.0820 , LMJLV39_170015300 , LMJSD75_170014900

Length:

550

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QEA8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QEA8

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	351	355	PF00656	0.704
CLV_NRD_NRD_1	135	137	PF00675	0.708
CLV_NRD_NRD_1	440	442	PF00675	0.731
CLV_PCSK_KEX2_1	135	137	PF00082	0.708
CLV_PCSK_KEX2_1	440	442	PF00082	0.731
CLV_PCSK_SKI1_1	3	7	PF00082	0.542
CLV_PCSK_SKI1_1	458	462	PF00082	0.737
DEG_SPOP_SBC_1	447	451	PF00917	0.752
DEG_SPOP_SBC_1	511	515	PF00917	0.724
DOC_MAPK_MEF2A_6	123	130	PF00069	0.728

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I516	Leptomonas seymouri	58%	98%
A0A3Q8IJG5	Leishmania donovani	96%	92%
A4H946	Leishmania braziliensis	85%	93%
A4HXG0	Leishmania infantum	96%	100%
E9AR55	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%

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