LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QEA5_LEIMA
TriTrypDb:
LmjF.17.0850 , LMJLV39_170015600 , LMJSD75_170015200
Length:
117

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QEA5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QEA5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 104 106 PF00675 0.485
CLV_NRD_NRD_1 112 114 PF00675 0.374
CLV_NRD_NRD_1 36 38 PF00675 0.579
CLV_NRD_NRD_1 92 94 PF00675 0.477
CLV_PCSK_KEX2_1 104 106 PF00082 0.337
CLV_PCSK_KEX2_1 112 114 PF00082 0.559
CLV_PCSK_KEX2_1 38 40 PF00082 0.570
CLV_PCSK_KEX2_1 84 86 PF00082 0.542
CLV_PCSK_PC1ET2_1 38 40 PF00082 0.570
CLV_PCSK_PC1ET2_1 84 86 PF00082 0.542
CLV_PCSK_SKI1_1 7 11 PF00082 0.677
CLV_PCSK_SKI1_1 87 91 PF00082 0.491
DOC_USP7_UBL2_3 110 114 PF12436 0.365
DOC_USP7_UBL2_3 25 29 PF12436 0.695
DOC_USP7_UBL2_3 63 67 PF12436 0.651
DOC_USP7_UBL2_3 90 94 PF12436 0.517
DOC_WW_Pin1_4 24 29 PF00397 0.601
LIG_14-3-3_CanoR_1 7 13 PF00244 0.676
LIG_BRCT_BRCA1_1 74 78 PF00533 0.581
LIG_FHA_2 57 63 PF00498 0.561
LIG_LIR_Gen_1 75 82 PF02991 0.593
LIG_LIR_Nem_3 75 81 PF02991 0.618
LIG_SUMO_SIM_anti_2 11 16 PF11976 0.675
MOD_CDK_SPK_2 24 29 PF00069 0.601
MOD_CK2_1 56 62 PF00069 0.557
MOD_Cter_Amidation 23 26 PF01082 0.662
MOD_GSK3_1 52 59 PF00069 0.523
MOD_NEK2_1 31 36 PF00069 0.565
MOD_NEK2_1 52 57 PF00069 0.529
MOD_PKA_2 31 37 PF00069 0.584
MOD_Plk_1 52 58 PF00069 0.531
MOD_ProDKin_1 24 30 PF00069 0.601
TRG_DiLeu_BaEn_4 53 59 PF01217 0.604
TRG_ER_diArg_1 103 105 PF00400 0.484
TRG_NLS_Bipartite_1 25 42 PF00514 0.657
TRG_NLS_MonoExtC_3 112 117 PF00514 0.511
TRG_NLS_MonoExtC_3 36 41 PF00514 0.667
TRG_NLS_MonoExtN_4 110 117 PF00514 0.476
TRG_NLS_MonoExtN_4 35 42 PF00514 0.575
TRG_Pf-PMV_PEXEL_1 104 109 PF00026 0.594

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0S4KMF1 Bodo saltans 49% 82%
A0A1X0NKS3 Trypanosomatidae 56% 98%
A0A3Q8IAX0 Leishmania donovani 97% 100%
A4H949 Leishmania braziliensis 85% 99%
A4HXG3 Leishmania infantum 97% 100%
C9ZNE7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 59% 92%
E9AR58 Leishmania mexicana (strain MHOM/GT/2001/U1103) 94% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS