WGS project CBMI000000000 data, contig

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QEA4_LEIMA

TriTrypDb:

LmjF.17.0860 , LMJLV39_170015700 , LMJSD75_170015300

Length:

147

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QEA4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QEA4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	85	89	PF00656	0.627
CLV_PCSK_SKI1_1	28	32	PF00082	0.602
DEG_MDM2_SWIB_1	7	14	PF02201	0.629
DOC_CKS1_1	123	128	PF01111	0.633
DOC_USP7_MATH_1	57	61	PF00917	0.626
DOC_USP7_MATH_1	71	75	PF00917	0.562
DOC_USP7_MATH_1	82	86	PF00917	0.650
DOC_USP7_MATH_1	93	97	PF00917	0.684
DOC_USP7_UBL2_3	20	24	PF12436	0.605
DOC_WW_Pin1_4	122	127	PF00397	0.638
LIG_14-3-3_CanoR_1	28	35	PF00244	0.621
LIG_14-3-3_CanoR_1	56	64	PF00244	0.606
LIG_BIR_II_1	1	5	PF00653	0.611
LIG_BRCT_BRCA1_1	3	7	PF00533	0.558
LIG_BRCT_BRCA1_1	73	77	PF00533	0.631
LIG_FHA_1	16	22	PF00498	0.643
LIG_FHA_2	14	20	PF00498	0.708
LIG_LIR_Apic_2	33	38	PF02991	0.663
LIG_LIR_Gen_1	109	119	PF02991	0.719
LIG_LIR_Nem_3	97	103	PF02991	0.669
LIG_Pex14_2	3	7	PF04695	0.606
LIG_SH2_CRK	100	104	PF00017	0.612
LIG_SH2_CRK	143	147	PF00017	0.687
LIG_SH2_CRK	35	39	PF00017	0.650
LIG_SH2_GRB2like	35	38	PF00017	0.656
LIG_SH2_NCK_1	35	39	PF00017	0.696
LIG_SH2_SRC	35	38	PF00017	0.656
LIG_SH2_STAP1	108	112	PF00017	0.607
LIG_SH2_STAT3	130	133	PF00017	0.720
LIG_SH2_STAT5	108	111	PF00017	0.723
LIG_SH2_STAT5	124	127	PF00017	0.701
MOD_CK1_1	13	19	PF00069	0.519
MOD_CK1_1	2	8	PF00069	0.611
MOD_CK1_1	47	53	PF00069	0.733
MOD_CK1_1	60	66	PF00069	0.536
MOD_CK2_1	13	19	PF00069	0.632
MOD_GlcNHglycan	41	44	PF01048	0.693
MOD_GlcNHglycan	57	60	PF01048	0.553
MOD_GlcNHglycan	84	87	PF01048	0.671
MOD_GSK3_1	47	54	PF00069	0.675
MOD_GSK3_1	60	67	PF00069	0.535
MOD_N-GLC_1	82	87	PF02516	0.643
MOD_NEK2_1	1	6	PF00069	0.610
MOD_NEK2_1	55	60	PF00069	0.602
MOD_NEK2_1	64	69	PF00069	0.582
MOD_NEK2_2	73	78	PF00069	0.561
MOD_NEK2_2	99	104	PF00069	0.538
MOD_PK_1	44	50	PF00069	0.605
MOD_PKA_2	51	57	PF00069	0.649
MOD_ProDKin_1	122	128	PF00069	0.634
TRG_DiLeu_BaEn_1	25	30	PF01217	0.648
TRG_ENDOCYTIC_2	100	103	PF00928	0.622
TRG_ENDOCYTIC_2	112	115	PF00928	0.545
TRG_ENDOCYTIC_2	143	146	PF00928	0.687

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IAS9	Leishmania donovani	89%	100%
A4H950	Leishmania braziliensis	55%	100%
A4HXG4	Leishmania infantum	90%	100%
E9AR59	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%