LeishMANIAdb
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Putative 5'-3' exonuclease

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative 5'-3' exonuclease
Gene product:
5'-3' exoribonuclease B, putative
Species:
Leishmania major
UniProt:
Q4QE76_LEIMA
TriTrypDb:
LmjF.17.1150 , LMJLV39_170018800 * , LMJSD75_170018600 *
Length:
1164

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 2
GO:0005737 cytoplasm 2 2
GO:0016020 membrane 2 9
GO:0043226 organelle 2 2
GO:0043227 membrane-bounded organelle 3 2
GO:0043229 intracellular organelle 3 2
GO:0043231 intracellular membrane-bounded organelle 4 2
GO:0110165 cellular anatomical entity 1 9

Expansion

Sequence features

Q4QE76
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QE76

Function

Biological processes
Term Name Level Count
GO:0000956 nuclear-transcribed mRNA catabolic process 7 2
GO:0006139 nucleobase-containing compound metabolic process 3 11
GO:0006401 RNA catabolic process 5 2
GO:0006402 mRNA catabolic process 6 2
GO:0006725 cellular aromatic compound metabolic process 3 11
GO:0006807 nitrogen compound metabolic process 2 11
GO:0008152 metabolic process 1 11
GO:0009056 catabolic process 2 2
GO:0009057 macromolecule catabolic process 4 2
GO:0009892 negative regulation of metabolic process 4 2
GO:0009987 cellular process 1 11
GO:0010468 regulation of gene expression 5 2
GO:0010605 negative regulation of macromolecule metabolic process 5 2
GO:0010629 negative regulation of gene expression 6 2
GO:0016070 RNA metabolic process 5 11
GO:0016071 mRNA metabolic process 6 2
GO:0019222 regulation of metabolic process 3 2
GO:0019439 aromatic compound catabolic process 4 2
GO:0034641 cellular nitrogen compound metabolic process 3 11
GO:0034655 nucleobase-containing compound catabolic process 4 2
GO:0043170 macromolecule metabolic process 3 11
GO:0044237 cellular metabolic process 2 11
GO:0044238 primary metabolic process 2 11
GO:0044248 cellular catabolic process 3 2
GO:0044260 obsolete cellular macromolecule metabolic process 3 2
GO:0044265 obsolete cellular macromolecule catabolic process 4 2
GO:0044270 cellular nitrogen compound catabolic process 4 2
GO:0046483 heterocycle metabolic process 3 11
GO:0046700 heterocycle catabolic process 4 2
GO:0048519 negative regulation of biological process 3 2
GO:0050789 regulation of biological process 2 2
GO:0060255 regulation of macromolecule metabolic process 4 2
GO:0065007 biological regulation 1 2
GO:0071704 organic substance metabolic process 2 11
GO:0090304 nucleic acid metabolic process 4 11
GO:1901360 organic cyclic compound metabolic process 3 11
GO:1901361 organic cyclic compound catabolic process 4 2
GO:1901575 organic substance catabolic process 3 2
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 11
GO:0003723 RNA binding 4 2
GO:0003824 catalytic activity 1 11
GO:0004518 nuclease activity 4 11
GO:0004527 exonuclease activity 5 11
GO:0004532 RNA exonuclease activity 5 2
GO:0004534 5'-3' RNA exonuclease activity 7 2
GO:0004540 RNA nuclease activity 4 2
GO:0005488 binding 1 11
GO:0008409 5'-3' exonuclease activity 6 2
GO:0016787 hydrolase activity 2 11
GO:0016788 hydrolase activity, acting on ester bonds 3 11
GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6 2
GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 6 2
GO:0043167 ion binding 2 11
GO:0043169 cation binding 3 11
GO:0046872 metal ion binding 4 11
GO:0097159 organic cyclic compound binding 2 11
GO:0140098 catalytic activity, acting on RNA 3 2
GO:0140640 catalytic activity, acting on a nucleic acid 2 2
GO:1901363 heterocyclic compound binding 2 11

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 413 417 PF00656 0.706
CLV_C14_Caspase3-7 490 494 PF00656 0.652
CLV_C14_Caspase3-7 858 862 PF00656 0.795
CLV_NRD_NRD_1 11 13 PF00675 0.361
CLV_NRD_NRD_1 1119 1121 PF00675 0.477
CLV_NRD_NRD_1 241 243 PF00675 0.351
CLV_NRD_NRD_1 372 374 PF00675 0.579
CLV_NRD_NRD_1 667 669 PF00675 0.376
CLV_NRD_NRD_1 894 896 PF00675 0.646
CLV_NRD_NRD_1 899 901 PF00675 0.625
CLV_NRD_NRD_1 97 99 PF00675 0.282
CLV_NRD_NRD_1 981 983 PF00675 0.503
CLV_NRD_NRD_1 990 992 PF00675 0.503
CLV_PCSK_FUR_1 1117 1121 PF00082 0.496
CLV_PCSK_FUR_1 95 99 PF00082 0.282
CLV_PCSK_KEX2_1 1119 1121 PF00082 0.466
CLV_PCSK_KEX2_1 241 243 PF00082 0.288
CLV_PCSK_KEX2_1 340 342 PF00082 0.463
CLV_PCSK_KEX2_1 372 374 PF00082 0.569
CLV_PCSK_KEX2_1 667 669 PF00082 0.405
CLV_PCSK_KEX2_1 894 896 PF00082 0.630
CLV_PCSK_KEX2_1 97 99 PF00082 0.282
CLV_PCSK_KEX2_1 981 983 PF00082 0.502
CLV_PCSK_KEX2_1 990 992 PF00082 0.525
CLV_PCSK_PC1ET2_1 340 342 PF00082 0.463
CLV_PCSK_PC7_1 237 243 PF00082 0.330
CLV_PCSK_SKI1_1 130 134 PF00082 0.275
CLV_PCSK_SKI1_1 606 610 PF00082 0.362
CLV_PCSK_SKI1_1 838 842 PF00082 0.321
DEG_APCC_KENBOX_2 246 250 PF00400 0.428
DEG_SCF_FBW7_1 1049 1055 PF00400 0.348
DEG_SPOP_SBC_1 559 563 PF00917 0.753
DEG_SPOP_SBC_1 675 679 PF00917 0.612
DOC_ANK_TNKS_1 690 697 PF00023 0.562
DOC_CKS1_1 1049 1054 PF01111 0.350
DOC_CKS1_1 890 895 PF01111 0.734
DOC_MAPK_gen_1 57 65 PF00069 0.534
DOC_MAPK_gen_1 667 675 PF00069 0.566
DOC_MAPK_gen_1 73 82 PF00069 0.534
DOC_MAPK_HePTP_8 70 82 PF00069 0.562
DOC_MAPK_MEF2A_6 1056 1064 PF00069 0.384
DOC_MAPK_MEF2A_6 1140 1147 PF00069 0.600
DOC_MAPK_MEF2A_6 57 65 PF00069 0.513
DOC_MAPK_MEF2A_6 702 711 PF00069 0.562
DOC_MAPK_MEF2A_6 73 82 PF00069 0.451
DOC_MAPK_MEF2A_6 804 812 PF00069 0.513
DOC_MAPK_RevD_3 966 982 PF00069 0.618
DOC_PP1_RVXF_1 745 751 PF00149 0.521
DOC_PP2B_LxvP_1 328 331 PF13499 0.513
DOC_PP2B_LxvP_1 743 746 PF13499 0.476
DOC_PP2B_LxvP_1 763 766 PF13499 0.585
DOC_PP4_FxxP_1 890 893 PF00568 0.801
DOC_USP7_MATH_1 145 149 PF00917 0.536
DOC_USP7_MATH_1 374 378 PF00917 0.732
DOC_USP7_MATH_1 530 534 PF00917 0.800
DOC_USP7_MATH_1 559 563 PF00917 0.661
DOC_USP7_MATH_1 645 649 PF00917 0.620
DOC_USP7_MATH_1 689 693 PF00917 0.584
DOC_USP7_MATH_1 825 829 PF00917 0.566
DOC_USP7_MATH_1 840 844 PF00917 0.484
DOC_USP7_MATH_1 856 860 PF00917 0.726
DOC_USP7_MATH_1 964 968 PF00917 0.719
DOC_USP7_MATH_1 972 976 PF00917 0.628
DOC_USP7_UBL2_3 243 247 PF12436 0.584
DOC_USP7_UBL2_3 361 365 PF12436 0.767
DOC_USP7_UBL2_3 537 541 PF12436 0.732
DOC_WW_Pin1_4 1048 1053 PF00397 0.404
DOC_WW_Pin1_4 210 215 PF00397 0.506
DOC_WW_Pin1_4 220 225 PF00397 0.455
DOC_WW_Pin1_4 259 264 PF00397 0.583
DOC_WW_Pin1_4 360 365 PF00397 0.783
DOC_WW_Pin1_4 386 391 PF00397 0.727
DOC_WW_Pin1_4 423 428 PF00397 0.766
DOC_WW_Pin1_4 429 434 PF00397 0.750
DOC_WW_Pin1_4 655 660 PF00397 0.626
DOC_WW_Pin1_4 751 756 PF00397 0.518
DOC_WW_Pin1_4 778 783 PF00397 0.560
DOC_WW_Pin1_4 864 869 PF00397 0.761
DOC_WW_Pin1_4 889 894 PF00397 0.799
DOC_WW_Pin1_4 928 933 PF00397 0.767
LIG_14-3-3_CanoR_1 298 306 PF00244 0.482
LIG_14-3-3_CanoR_1 341 345 PF00244 0.687
LIG_14-3-3_CanoR_1 373 381 PF00244 0.769
LIG_14-3-3_CanoR_1 676 681 PF00244 0.600
LIG_14-3-3_CanoR_1 702 711 PF00244 0.535
LIG_14-3-3_CanoR_1 776 780 PF00244 0.562
LIG_14-3-3_CanoR_1 955 960 PF00244 0.677
LIG_14-3-3_CanoR_1 97 106 PF00244 0.562
LIG_APCC_ABBA_1 811 816 PF00400 0.513
LIG_BIR_III_2 865 869 PF00653 0.762
LIG_BIR_III_4 250 254 PF00653 0.428
LIG_BRCT_BRCA1_1 1111 1115 PF00533 0.636
LIG_Clathr_ClatBox_1 623 627 PF01394 0.551
LIG_deltaCOP1_diTrp_1 749 756 PF00928 0.521
LIG_EH1_1 805 813 PF00400 0.428
LIG_eIF4E_1 802 808 PF01652 0.525
LIG_EVH1_2 752 756 PF00568 0.496
LIG_FHA_1 160 166 PF00498 0.553
LIG_FHA_1 357 363 PF00498 0.753
LIG_FHA_1 65 71 PF00498 0.557
LIG_FHA_1 656 662 PF00498 0.640
LIG_FHA_1 675 681 PF00498 0.438
LIG_FHA_1 807 813 PF00498 0.511
LIG_FHA_1 937 943 PF00498 0.682
LIG_FHA_1 960 966 PF00498 0.639
LIG_FHA_2 105 111 PF00498 0.521
LIG_FHA_2 131 137 PF00498 0.484
LIG_FHA_2 283 289 PF00498 0.482
LIG_FHA_2 51 57 PF00498 0.551
LIG_FHA_2 597 603 PF00498 0.541
LIG_FHA_2 613 619 PF00498 0.562
LIG_FHA_2 650 656 PF00498 0.551
LIG_FHA_2 828 834 PF00498 0.487
LIG_FHA_2 929 935 PF00498 0.592
LIG_G3BP_FGDF_1 1024 1029 PF02136 0.447
LIG_GBD_Chelix_1 724 732 PF00786 0.368
LIG_Integrin_RGD_1 485 487 PF01839 0.541
LIG_LIR_Apic_2 712 718 PF02991 0.467
LIG_LIR_Apic_2 749 753 PF02991 0.521
LIG_LIR_Apic_2 958 964 PF02991 0.786
LIG_LIR_Gen_1 1044 1052 PF02991 0.598
LIG_LIR_Gen_1 1071 1081 PF02991 0.376
LIG_LIR_Gen_1 1097 1103 PF02991 0.738
LIG_LIR_Gen_1 320 331 PF02991 0.496
LIG_LIR_Gen_1 454 465 PF02991 0.562
LIG_LIR_Gen_1 570 579 PF02991 0.534
LIG_LIR_Gen_1 754 764 PF02991 0.496
LIG_LIR_Gen_1 873 881 PF02991 0.655
LIG_LIR_LC3C_4 66 70 PF02991 0.562
LIG_LIR_Nem_3 1044 1049 PF02991 0.639
LIG_LIR_Nem_3 1055 1061 PF02991 0.432
LIG_LIR_Nem_3 1071 1076 PF02991 0.297
LIG_LIR_Nem_3 1097 1102 PF02991 0.744
LIG_LIR_Nem_3 301 306 PF02991 0.513
LIG_LIR_Nem_3 320 326 PF02991 0.496
LIG_LIR_Nem_3 454 460 PF02991 0.563
LIG_LIR_Nem_3 570 575 PF02991 0.557
LIG_LIR_Nem_3 712 716 PF02991 0.499
LIG_LIR_Nem_3 754 759 PF02991 0.496
LIG_LIR_Nem_3 873 879 PF02991 0.656
LIG_LYPXL_yS_3 14 17 PF13949 0.513
LIG_NRBOX 574 580 PF00104 0.534
LIG_NRBOX 625 631 PF00104 0.527
LIG_PCNA_yPIPBox_3 142 156 PF02747 0.562
LIG_PDZ_Class_1 1159 1164 PF00595 0.684
LIG_Pex14_1 670 674 PF04695 0.538
LIG_Pex14_1 713 717 PF04695 0.482
LIG_Pex14_2 790 794 PF04695 0.482
LIG_SH2_CRK 611 615 PF00017 0.482
LIG_SH2_CRK 704 708 PF00017 0.556
LIG_SH2_CRK 961 965 PF00017 0.794
LIG_SH2_NCK_1 633 637 PF00017 0.496
LIG_SH2_NCK_1 704 708 PF00017 0.562
LIG_SH2_NCK_1 831 835 PF00017 0.521
LIG_SH2_PTP2 30 33 PF00017 0.496
LIG_SH2_PTP2 79 82 PF00017 0.534
LIG_SH2_SRC 1128 1131 PF00017 0.718
LIG_SH2_SRC 693 696 PF00017 0.482
LIG_SH2_STAP1 1155 1159 PF00017 0.706
LIG_SH2_STAP1 344 348 PF00017 0.730
LIG_SH2_STAP1 619 623 PF00017 0.554
LIG_SH2_STAP1 959 963 PF00017 0.699
LIG_SH2_STAT3 619 622 PF00017 0.496
LIG_SH2_STAT3 916 919 PF00017 0.641
LIG_SH2_STAT5 1159 1162 PF00017 0.683
LIG_SH2_STAT5 239 242 PF00017 0.565
LIG_SH2_STAT5 30 33 PF00017 0.482
LIG_SH2_STAT5 459 462 PF00017 0.547
LIG_SH2_STAT5 591 594 PF00017 0.501
LIG_SH2_STAT5 604 607 PF00017 0.436
LIG_SH2_STAT5 613 616 PF00017 0.482
LIG_SH2_STAT5 674 677 PF00017 0.541
LIG_SH2_STAT5 693 696 PF00017 0.470
LIG_SH2_STAT5 79 82 PF00017 0.496
LIG_SH2_STAT5 831 834 PF00017 0.535
LIG_SH2_STAT5 961 964 PF00017 0.665
LIG_SH2_STAT5 985 988 PF00017 0.651
LIG_SH3_1 1140 1146 PF00018 0.723
LIG_SH3_2 1127 1132 PF14604 0.701
LIG_SH3_3 1124 1130 PF00018 0.678
LIG_SH3_3 1140 1146 PF00018 0.608
LIG_SH3_3 368 374 PF00018 0.767
LIG_SH3_3 424 430 PF00018 0.776
LIG_SH3_3 447 453 PF00018 0.742
LIG_SH3_3 547 553 PF00018 0.729
LIG_SH3_3 582 588 PF00018 0.482
LIG_SH3_3 749 755 PF00018 0.516
LIG_SH3_3 807 813 PF00018 0.473
LIG_SH3_3 946 952 PF00018 0.715
LIG_SH3_3 960 966 PF00018 0.720
LIG_SH3_CIN85_PxpxPR_1 889 894 PF14604 0.760
LIG_SUMO_SIM_anti_2 461 466 PF11976 0.623
LIG_SUMO_SIM_anti_2 944 951 PF11976 0.685
LIG_SUMO_SIM_anti_2 967 973 PF11976 0.705
LIG_SUMO_SIM_par_1 332 338 PF11976 0.534
LIG_SUMO_SIM_par_1 66 71 PF11976 0.584
LIG_SUMO_SIM_par_1 722 727 PF11976 0.554
LIG_TRAF2_1 53 56 PF00917 0.482
LIG_TYR_ITIM 609 614 PF00017 0.482
LIG_TYR_ITIM 77 82 PF00017 0.534
MOD_CDC14_SPxK_1 213 216 PF00782 0.521
MOD_CDC14_SPxK_1 897 900 PF00782 0.758
MOD_CDK_SPK_2 360 365 PF00069 0.706
MOD_CDK_SPK_2 889 894 PF00069 0.729
MOD_CDK_SPxK_1 210 216 PF00069 0.521
MOD_CDK_SPxK_1 889 895 PF00069 0.801
MOD_CDK_SPxxK_3 360 367 PF00069 0.716
MOD_CDK_SPxxK_3 894 901 PF00069 0.764
MOD_CK1_1 1050 1056 PF00069 0.500
MOD_CK1_1 1088 1094 PF00069 0.758
MOD_CK1_1 1097 1103 PF00069 0.746
MOD_CK1_1 223 229 PF00069 0.482
MOD_CK1_1 377 383 PF00069 0.768
MOD_CK1_1 386 392 PF00069 0.765
MOD_CK1_1 429 435 PF00069 0.712
MOD_CK1_1 468 474 PF00069 0.580
MOD_CK1_1 705 711 PF00069 0.488
MOD_CK1_1 921 927 PF00069 0.723
MOD_CK2_1 130 136 PF00069 0.481
MOD_CK2_1 282 288 PF00069 0.482
MOD_CK2_1 339 345 PF00069 0.740
MOD_CK2_1 408 414 PF00069 0.753
MOD_CK2_1 452 458 PF00069 0.563
MOD_CK2_1 50 56 PF00069 0.533
MOD_CK2_1 507 513 PF00069 0.693
MOD_CK2_1 612 618 PF00069 0.521
MOD_CK2_1 689 695 PF00069 0.547
MOD_CK2_1 827 833 PF00069 0.487
MOD_CK2_1 924 930 PF00069 0.768
MOD_CK2_1 942 948 PF00069 0.600
MOD_CK2_1 993 999 PF00069 0.766
MOD_Cter_Amidation 192 195 PF01082 0.227
MOD_Cter_Amidation 988 991 PF01082 0.609
MOD_DYRK1A_RPxSP_1 423 427 PF00069 0.652
MOD_GlcNHglycan 101 104 PF01048 0.351
MOD_GlcNHglycan 1087 1090 PF01048 0.462
MOD_GlcNHglycan 1107 1110 PF01048 0.294
MOD_GlcNHglycan 120 123 PF01048 0.162
MOD_GlcNHglycan 300 303 PF01048 0.344
MOD_GlcNHglycan 308 311 PF01048 0.319
MOD_GlcNHglycan 385 388 PF01048 0.556
MOD_GlcNHglycan 454 457 PF01048 0.482
MOD_GlcNHglycan 496 499 PF01048 0.492
MOD_GlcNHglycan 523 527 PF01048 0.612
MOD_GlcNHglycan 531 535 PF01048 0.574
MOD_GlcNHglycan 594 597 PF01048 0.305
MOD_GlcNHglycan 647 650 PF01048 0.458
MOD_GlcNHglycan 662 665 PF01048 0.410
MOD_GlcNHglycan 827 830 PF01048 0.363
MOD_GlcNHglycan 842 845 PF01048 0.309
MOD_GlcNHglycan 907 910 PF01048 0.565
MOD_GlcNHglycan 920 923 PF01048 0.460
MOD_GlcNHglycan 926 929 PF01048 0.389
MOD_GlcNHglycan 994 998 PF01048 0.593
MOD_GSK3_1 1037 1044 PF00069 0.431
MOD_GSK3_1 1048 1055 PF00069 0.463
MOD_GSK3_1 1105 1112 PF00069 0.635
MOD_GSK3_1 114 121 PF00069 0.555
MOD_GSK3_1 181 188 PF00069 0.559
MOD_GSK3_1 216 223 PF00069 0.500
MOD_GSK3_1 274 281 PF00069 0.458
MOD_GSK3_1 349 356 PF00069 0.747
MOD_GSK3_1 375 382 PF00069 0.732
MOD_GSK3_1 401 408 PF00069 0.786
MOD_GSK3_1 421 428 PF00069 0.719
MOD_GSK3_1 559 566 PF00069 0.617
MOD_GSK3_1 592 599 PF00069 0.562
MOD_GSK3_1 64 71 PF00069 0.568
MOD_GSK3_1 645 652 PF00069 0.585
MOD_GSK3_1 705 712 PF00069 0.468
MOD_GSK3_1 825 832 PF00069 0.584
MOD_GSK3_1 856 863 PF00069 0.776
MOD_GSK3_1 866 873 PF00069 0.829
MOD_GSK3_1 918 925 PF00069 0.772
MOD_GSK3_1 951 958 PF00069 0.694
MOD_N-GLC_1 1113 1118 PF02516 0.437
MOD_N-GLC_1 306 311 PF02516 0.362
MOD_N-GLC_1 874 879 PF02516 0.612
MOD_NEK2_1 1136 1141 PF00069 0.698
MOD_NEK2_1 120 125 PF00069 0.540
MOD_NEK2_1 280 285 PF00069 0.534
MOD_NEK2_1 296 301 PF00069 0.486
MOD_NEK2_1 306 311 PF00069 0.457
MOD_NEK2_1 324 329 PF00069 0.482
MOD_NEK2_1 379 384 PF00069 0.765
MOD_NEK2_1 68 73 PF00069 0.482
MOD_NEK2_1 709 714 PF00069 0.551
MOD_NEK2_1 775 780 PF00069 0.514
MOD_NEK2_1 786 791 PF00069 0.450
MOD_NEK2_2 649 654 PF00069 0.501
MOD_PIKK_1 130 136 PF00454 0.584
MOD_PIKK_1 145 151 PF00454 0.408
MOD_PIKK_1 296 302 PF00454 0.496
MOD_PIKK_1 50 56 PF00454 0.521
MOD_PK_1 57 63 PF00069 0.550
MOD_PKA_1 340 346 PF00069 0.752
MOD_PKA_2 1094 1100 PF00069 0.686
MOD_PKA_2 340 346 PF00069 0.690
MOD_PKA_2 675 681 PF00069 0.584
MOD_PKA_2 775 781 PF00069 0.527
MOD_PKB_1 1006 1014 PF00069 0.576
MOD_PKB_1 955 963 PF00069 0.698
MOD_PKB_1 991 999 PF00069 0.754
MOD_Plk_1 1041 1047 PF00069 0.476
MOD_Plk_1 936 942 PF00069 0.676
MOD_Plk_4 1041 1047 PF00069 0.394
MOD_Plk_4 1068 1074 PF00069 0.397
MOD_Plk_4 1094 1100 PF00069 0.708
MOD_Plk_4 120 126 PF00069 0.577
MOD_Plk_4 13 19 PF00069 0.556
MOD_Plk_4 274 280 PF00069 0.518
MOD_Plk_4 353 359 PF00069 0.755
MOD_Plk_4 465 471 PF00069 0.595
MOD_Plk_4 586 592 PF00069 0.524
MOD_Plk_4 596 602 PF00069 0.520
MOD_Plk_4 64 70 PF00069 0.584
MOD_Plk_4 806 812 PF00069 0.479
MOD_Plk_4 942 948 PF00069 0.688
MOD_Plk_4 966 972 PF00069 0.748
MOD_ProDKin_1 1048 1054 PF00069 0.406
MOD_ProDKin_1 210 216 PF00069 0.506
MOD_ProDKin_1 220 226 PF00069 0.455
MOD_ProDKin_1 259 265 PF00069 0.583
MOD_ProDKin_1 360 366 PF00069 0.781
MOD_ProDKin_1 386 392 PF00069 0.727
MOD_ProDKin_1 423 429 PF00069 0.766
MOD_ProDKin_1 655 661 PF00069 0.600
MOD_ProDKin_1 751 757 PF00069 0.518
MOD_ProDKin_1 778 784 PF00069 0.560
MOD_ProDKin_1 864 870 PF00069 0.761
MOD_ProDKin_1 889 895 PF00069 0.801
MOD_ProDKin_1 928 934 PF00069 0.762
MOD_SUMO_for_1 528 531 PF00179 0.649
MOD_SUMO_for_1 746 749 PF00179 0.551
MOD_SUMO_rev_2 288 294 PF00179 0.486
MOD_SUMO_rev_2 521 530 PF00179 0.728
TRG_DiLeu_BaEn_2 694 700 PF01217 0.482
TRG_DiLeu_BaLyEn_6 625 630 PF01217 0.522
TRG_ENDOCYTIC_2 14 17 PF00928 0.505
TRG_ENDOCYTIC_2 30 33 PF00928 0.425
TRG_ENDOCYTIC_2 457 460 PF00928 0.534
TRG_ENDOCYTIC_2 611 614 PF00928 0.482
TRG_ENDOCYTIC_2 633 636 PF00928 0.504
TRG_ENDOCYTIC_2 704 707 PF00928 0.524
TRG_ENDOCYTIC_2 716 719 PF00928 0.469
TRG_ENDOCYTIC_2 79 82 PF00928 0.513
TRG_ER_diArg_1 1117 1120 PF00400 0.706
TRG_ER_diArg_1 240 242 PF00400 0.459
TRG_ER_diArg_1 371 373 PF00400 0.778
TRG_ER_diArg_1 893 895 PF00400 0.846
TRG_ER_diArg_1 95 98 PF00400 0.482
TRG_ER_diArg_1 981 983 PF00400 0.705
TRG_ER_diArg_1 990 993 PF00400 0.734
TRG_Pf-PMV_PEXEL_1 142 146 PF00026 0.331
TRG_Pf-PMV_PEXEL_1 768 773 PF00026 0.353

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PCR5 Leptomonas seymouri 56% 100%
A0A0S4JAB4 Bodo saltans 34% 100%
A0A3S5H716 Leishmania donovani 91% 100%
A0A422NS66 Trypanosoma rangeli 42% 100%
A4H970 Leishmania braziliensis 70% 100%
A4HXJ2 Leishmania infantum 91% 100%
C9ZP82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
E9AR87 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%
V5AZC6 Trypanosoma cruzi 37% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS