LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QE63_LEIMA
TriTrypDb:
LmjF.17.1280 , LMJLV39_170020200 , LMJSD75_170019900
Length:
67

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 15
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 8
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 7
GO:0110165 cellular anatomical entity 1 7
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Expansion

Sequence features

Q4QE63
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QE63

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_PCSK_KEX2_1 43 45 PF00082 0.452
CLV_PCSK_PC1ET2_1 43 45 PF00082 0.452
CLV_PCSK_SKI1_1 32 36 PF00082 0.363
DOC_CYCLIN_yCln2_LP_2 24 30 PF00134 0.363
DOC_MAPK_MEF2A_6 15 24 PF00069 0.305
DOC_PP2B_LxvP_1 24 27 PF13499 0.363
LIG_BIR_II_1 1 5 PF00653 0.355
LIG_LIR_Gen_1 53 63 PF02991 0.570
LIG_LIR_Nem_3 53 58 PF02991 0.567
LIG_Pex14_1 5 9 PF04695 0.312
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P7R6 Leptomonas seymouri 74% 96%
A0A0S4JAP6 Bodo saltans 60% 100%
A0A3Q8IAT0 Leishmania donovani 96% 100%
A4H987 Leishmania braziliensis 91% 100%
A4HXK5 Leishmania infantum 94% 100%
C9ZP95 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 62% 92%
E9ARA0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
V5DFS3 Trypanosoma cruzi 68% 92%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS