Carn_acyltransf domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QE52_LEIMA

TriTrypDb:

LmjF.17.1375 , LMJLV39_170021300 , LMJSD75_170021000

Length:

128

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QE52

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QE52

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	95	97	PF00675	0.469
CLV_PCSK_FUR_1	93	97	PF00082	0.481
CLV_PCSK_KEX2_1	50	52	PF00082	0.393
CLV_PCSK_KEX2_1	95	97	PF00082	0.476
CLV_PCSK_PC1ET2_1	50	52	PF00082	0.393
CLV_PCSK_SKI1_1	50	54	PF00082	0.480
CLV_PCSK_SKI1_1	74	78	PF00082	0.502
CLV_PCSK_SKI1_1	85	89	PF00082	0.545
DOC_PP1_RVXF_1	54	61	PF00149	0.511
DOC_PP4_FxxP_1	23	26	PF00568	0.577
DOC_PP4_FxxP_1	60	63	PF00568	0.442
DOC_USP7_MATH_1	26	30	PF00917	0.632
DOC_WW_Pin1_4	104	109	PF00397	0.548
DOC_WW_Pin1_4	11	16	PF00397	0.474
DOC_WW_Pin1_4	18	23	PF00397	0.451
DOC_WW_Pin1_4	31	36	PF00397	0.421
LIG_Actin_WH2_2	62	79	PF00022	0.455
LIG_BIR_II_1	1	5	PF00653	0.641
LIG_CSL_BTD_1	105	108	PF09270	0.551
LIG_FHA_1	53	59	PF00498	0.481
LIG_FHA_1	86	92	PF00498	0.356
LIG_LIR_Apic_2	21	26	PF02991	0.564
LIG_LIR_Nem_3	14	20	PF02991	0.546
LIG_PDZ_Class_2	123	128	PF00595	0.440
LIG_SH2_PTP2	17	20	PF00017	0.564
LIG_SH2_STAP1	45	49	PF00017	0.464
LIG_SH2_STAT5	112	115	PF00017	0.486
LIG_SH2_STAT5	17	20	PF00017	0.572
LIG_SH2_STAT5	45	48	PF00017	0.492
LIG_SH3_3	102	108	PF00018	0.518
MOD_CDC14_SPxK_1	21	24	PF00782	0.404
MOD_CDK_SPK_2	104	109	PF00069	0.548
MOD_CDK_SPK_2	11	16	PF00069	0.524
MOD_CDK_SPxK_1	18	24	PF00069	0.389
MOD_CK1_1	11	17	PF00069	0.492
MOD_CK2_1	38	44	PF00069	0.535
MOD_GlcNHglycan	88	91	PF01048	0.492
MOD_GSK3_1	26	33	PF00069	0.591
MOD_GSK3_1	7	14	PF00069	0.567
MOD_GSK3_1	95	102	PF00069	0.602
MOD_NEK2_1	122	127	PF00069	0.582
MOD_NEK2_1	6	11	PF00069	0.518
MOD_NEK2_1	76	81	PF00069	0.447
MOD_PIKK_1	99	105	PF00454	0.521
MOD_PKA_1	95	101	PF00069	0.475
MOD_PKA_2	95	101	PF00069	0.475
MOD_PKB_1	93	101	PF00069	0.480
MOD_Plk_1	122	128	PF00069	0.514
MOD_Plk_1	43	49	PF00069	0.500
MOD_Plk_4	77	83	PF00069	0.573
MOD_Plk_4	8	14	PF00069	0.472
MOD_ProDKin_1	104	110	PF00069	0.548
MOD_ProDKin_1	11	17	PF00069	0.476
MOD_ProDKin_1	18	24	PF00069	0.462
MOD_ProDKin_1	31	37	PF00069	0.419
TRG_ENDOCYTIC_2	17	20	PF00928	0.593
TRG_ER_diArg_1	92	95	PF00400	0.475

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P845	Leptomonas seymouri	68%	96%
A0A0S4J864	Bodo saltans	36%	99%
A0A1X0NSP0	Trypanosomatidae	52%	100%
A0A3R7MB48	Trypanosoma rangeli	52%	100%
A0A3S7WUQ8	Leishmania donovani	91%	99%
A4H994	Leishmania braziliensis	85%	99%
A4HXL5	Leishmania infantum	91%	99%
C9ZPA9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	54%	100%
E9ARB1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	99%