Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QE16_LEIMA

TriTrypDb:

LmjF.18.0260 , LMJLV39_180008000 , LMJSD75_180007900

Length:

118


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	2
GO:0020023	kinetoplast	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Q4QE16

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QE16

PDB structure(s): 7aih_BE , 7am2_BE , 7ane_BE


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	13	15	PF00675	0.659
CLV_NRD_NRD_1	49	51	PF00675	0.441
CLV_PCSK_KEX2_1	13	15	PF00082	0.680
CLV_PCSK_KEX2_1	49	51	PF00082	0.441
DEG_Nend_Nbox_1	1	3	PF02207	0.693
DOC_CKS1_1	25	30	PF01111	0.625
DOC_CYCLIN_yCln2_LP_2	20	26	PF00134	0.454
DOC_MAPK_MEF2A_6	95	104	PF00069	0.444
DOC_PP1_RVXF_1	47	54	PF00149	0.459
DOC_PP4_FxxP_1	73	76	PF00568	0.505
DOC_WW_Pin1_4	107	112	PF00397	0.423
DOC_WW_Pin1_4	19	24	PF00397	0.631
LIG_14-3-3_CanoR_1	13	17	PF00244	0.647
LIG_14-3-3_CanoR_1	30	35	PF00244	0.487
LIG_14-3-3_CanoR_1	49	54	PF00244	0.395
LIG_LIR_Apic_2	71	76	PF02991	0.494
LIG_REV1ctd_RIR_1	37	46	PF16727	0.479
LIG_SH2_STAT5	103	106	PF00017	0.339
LIG_SH2_STAT5	86	89	PF00017	0.498
MOD_CDK_SPxK_1	24	30	PF00069	0.626
MOD_CK1_1	33	39	PF00069	0.496
MOD_CK1_1	80	86	PF00069	0.542
MOD_CK2_1	112	118	PF00069	0.455
MOD_GSK3_1	26	33	PF00069	0.568
MOD_LATS_1	47	53	PF00433	0.480
MOD_N-GLC_1	107	112	PF02516	0.423
MOD_NEK2_1	68	73	PF00069	0.458
MOD_PK_1	30	36	PF00069	0.485
MOD_PKA_1	49	55	PF00069	0.441
MOD_PKA_2	12	18	PF00069	0.650
MOD_PKA_2	49	55	PF00069	0.441
MOD_ProDKin_1	107	113	PF00069	0.420
MOD_ProDKin_1	19	25	PF00069	0.631
TRG_ER_diArg_1	49	51	PF00400	0.457


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IHE6	Leptomonas seymouri	89%	91%
A0A1X0P6R5	Trypanosomatidae	72%	100%
A0A3Q8ICZ2	Leishmania donovani	98%	100%
A0A3S5IS44	Trypanosoma rangeli	76%	100%
A4H9D0	Leishmania braziliensis	94%	100%
A4HXQ2	Leishmania infantum	98%	100%
B6DTE3	Bodo saltans	74%	100%
D0A030	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	76%	100%
E9ARG3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%