acidPPc domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QDZ9_LEIMA

TriTrypDb:

LmjF.18.0430 , LMJLV39_180009700 , LMJSD75_180009600

Length:

223

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

Q4QDZ9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QDZ9

Function

Biological processes
Term	Name	Level	Count
GO:0006629	lipid metabolic process	3	1
GO:0006644	phospholipid metabolic process	4	1
GO:0006793	phosphorus metabolic process	3	1
GO:0006796	phosphate-containing compound metabolic process	4	1
GO:0008152	metabolic process	1	1
GO:0009987	cellular process	1	1
GO:0019637	organophosphate metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044255	cellular lipid metabolic process	3	1
GO:0071704	organic substance metabolic process	2	1

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	109	111	PF00675	0.442
CLV_NRD_NRD_1	195	197	PF00675	0.476
CLV_NRD_NRD_1	220	222	PF00675	0.434
CLV_PCSK_FUR_1	107	111	PF00082	0.447
CLV_PCSK_KEX2_1	109	111	PF00082	0.442
CLV_PCSK_KEX2_1	194	196	PF00082	0.481
CLV_PCSK_SKI1_1	110	114	PF00082	0.451
DEG_APCC_DBOX_1	108	116	PF00400	0.654
DEG_Nend_Nbox_1	1	3	PF02207	0.269
DOC_CYCLIN_yCln2_LP_2	3	9	PF00134	0.305
DOC_PP2B_LxvP_1	3	6	PF13499	0.305
DOC_PP2B_LxvP_1	7	10	PF13499	0.284
DOC_USP7_MATH_1	101	105	PF00917	0.645
DOC_USP7_MATH_1	128	132	PF00917	0.666
DOC_USP7_MATH_1	146	150	PF00917	0.582
DOC_USP7_MATH_1	155	159	PF00917	0.608
DOC_WW_Pin1_4	116	121	PF00397	0.644
DOC_WW_Pin1_4	181	186	PF00397	0.665
DOC_WW_Pin1_4	188	193	PF00397	0.646
DOC_WW_Pin1_4	206	211	PF00397	0.616
DOC_WW_Pin1_4	91	96	PF00397	0.650
LIG_14-3-3_CanoR_1	17	25	PF00244	0.274
LIG_14-3-3_CanoR_1	174	183	PF00244	0.656
LIG_14-3-3_CanoR_1	194	204	PF00244	0.606
LIG_APCC_ABBAyCdc20_2	48	54	PF00400	0.574
LIG_BRCT_BRCA1_1	102	106	PF00533	0.622
LIG_DCNL_PONY_1	1	4	PF03556	0.269
LIG_FHA_1	10	16	PF00498	0.285
LIG_FHA_1	65	71	PF00498	0.637
LIG_FHA_2	54	60	PF00498	0.720
LIG_LIR_Apic_2	56	61	PF02991	0.601
LIG_LIR_Apic_2	89	95	PF02991	0.635
LIG_LIR_Nem_3	54	58	PF02991	0.618
LIG_MLH1_MIPbox_1	102	106	PF16413	0.622
LIG_REV1ctd_RIR_1	103	114	PF16727	0.623
LIG_SH2_CRK	92	96	PF00017	0.624
LIG_SH2_NCK_1	58	62	PF00017	0.611
LIG_SH2_NCK_1	92	96	PF00017	0.624
LIG_SH2_SRC	58	61	PF00017	0.613
LIG_SH3_1	92	98	PF00018	0.618
LIG_SH3_3	148	154	PF00018	0.650
LIG_SH3_3	201	207	PF00018	0.697
LIG_SH3_3	92	98	PF00018	0.804
LIG_SUMO_SIM_par_1	11	16	PF11976	0.305
LIG_WRC_WIRS_1	44	49	PF05994	0.269
MOD_CDC14_SPxK_1	191	194	PF00782	0.658
MOD_CDK_SPK_2	116	121	PF00069	0.644
MOD_CDK_SPxK_1	188	194	PF00069	0.660
MOD_CDK_SPxxK_3	116	123	PF00069	0.646
MOD_CDK_SPxxK_3	188	195	PF00069	0.659
MOD_CK1_1	126	132	PF00069	0.686
MOD_CK1_1	138	144	PF00069	0.619
MOD_CK1_1	158	164	PF00069	0.611
MOD_CK1_1	16	22	PF00069	0.274
MOD_CK2_1	195	201	PF00069	0.754
MOD_GlcNHglycan	125	128	PF01048	0.491
MOD_GlcNHglycan	143	146	PF01048	0.398
MOD_GlcNHglycan	157	160	PF01048	0.427
MOD_GlcNHglycan	197	200	PF01048	0.459
MOD_GSK3_1	129	136	PF00069	0.665
MOD_GSK3_1	154	161	PF00069	0.656
MOD_GSK3_1	206	213	PF00069	0.637
MOD_GSK3_1	29	36	PF00069	0.199
MOD_GSK3_1	39	46	PF00069	0.252
MOD_GSK3_1	82	89	PF00069	0.644
MOD_GSK3_1	9	16	PF00069	0.305
MOD_N-GLC_1	210	215	PF02516	0.440
MOD_N-GLC_1	82	87	PF02516	0.441
MOD_NEK2_1	29	34	PF00069	0.305
MOD_NEK2_2	101	106	PF00069	0.621
MOD_NEK2_2	53	58	PF00069	0.590
MOD_PIKK_1	64	70	PF00454	0.607
MOD_PKA_1	195	201	PF00069	0.681
MOD_PKA_2	16	22	PF00069	0.274
MOD_PKA_2	173	179	PF00069	0.646
MOD_PKA_2	195	201	PF00069	0.673
MOD_PKA_2	47	53	PF00069	0.644
MOD_PKB_1	172	180	PF00069	0.644
MOD_Plk_1	53	59	PF00069	0.619
MOD_Plk_4	101	107	PF00069	0.622
MOD_Plk_4	146	152	PF00069	0.639
MOD_Plk_4	158	164	PF00069	0.631
MOD_Plk_4	33	39	PF00069	0.305
MOD_ProDKin_1	116	122	PF00069	0.645
MOD_ProDKin_1	181	187	PF00069	0.666
MOD_ProDKin_1	188	194	PF00069	0.646
MOD_ProDKin_1	206	212	PF00069	0.617
MOD_ProDKin_1	91	97	PF00069	0.645
MOD_SUMO_rev_2	108	115	PF00179	0.627
MOD_SUMO_rev_2	129	136	PF00179	0.646
TRG_DiLeu_BaEn_1	66	71	PF01217	0.616
TRG_DiLeu_BaLyEn_6	3	8	PF01217	0.305
TRG_ER_diArg_1	194	196	PF00400	0.657

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9ARI0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	66%	81%