Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QDU9_LEIMA

TriTrypDb:

LmjF.18.0930 , LMJLV39_180014800 , LMJSD75_180014700

Length:

875

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QDU9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QDU9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	149	153	PF00656	0.761
CLV_C14_Caspase3-7	205	209	PF00656	0.620
CLV_C14_Caspase3-7	448	452	PF00656	0.800
CLV_C14_Caspase3-7	507	511	PF00656	0.583
CLV_C14_Caspase3-7	575	579	PF00656	0.583
CLV_NRD_NRD_1	184	186	PF00675	0.501
CLV_NRD_NRD_1	216	218	PF00675	0.563
CLV_NRD_NRD_1	328	330	PF00675	0.783
CLV_NRD_NRD_1	399	401	PF00675	0.806
CLV_NRD_NRD_1	501	503	PF00675	0.758
CLV_NRD_NRD_1	630	632	PF00675	0.471
CLV_NRD_NRD_1	673	675	PF00675	0.515
CLV_NRD_NRD_1	697	699	PF00675	0.685
CLV_NRD_NRD_1	715	717	PF00675	0.479
CLV_NRD_NRD_1	756	758	PF00675	0.823
CLV_NRD_NRD_1	78	80	PF00675	0.640
CLV_NRD_NRD_1	834	836	PF00675	0.713
CLV_NRD_NRD_1	871	873	PF00675	0.806
CLV_PCSK_FUR_1	628	632	PF00082	0.554
CLV_PCSK_FUR_1	671	675	PF00082	0.573
CLV_PCSK_KEX2_1	184	186	PF00082	0.466
CLV_PCSK_KEX2_1	260	262	PF00082	0.733
CLV_PCSK_KEX2_1	501	503	PF00082	0.758
CLV_PCSK_KEX2_1	630	632	PF00082	0.471
CLV_PCSK_KEX2_1	673	675	PF00082	0.527
CLV_PCSK_KEX2_1	697	699	PF00082	0.685
CLV_PCSK_KEX2_1	714	716	PF00082	0.481
CLV_PCSK_KEX2_1	756	758	PF00082	0.823
CLV_PCSK_KEX2_1	78	80	PF00082	0.640
CLV_PCSK_KEX2_1	834	836	PF00082	0.713
CLV_PCSK_KEX2_1	871	873	PF00082	0.806
CLV_PCSK_PC1ET2_1	260	262	PF00082	0.842
CLV_PCSK_SKI1_1	124	128	PF00082	0.728
CLV_PCSK_SKI1_1	184	188	PF00082	0.621
CLV_PCSK_SKI1_1	257	261	PF00082	0.823
CLV_PCSK_SKI1_1	39	43	PF00082	0.627
CLV_PCSK_SKI1_1	502	506	PF00082	0.825
CLV_PCSK_SKI1_1	528	532	PF00082	0.700
CLV_PCSK_SKI1_1	673	677	PF00082	0.644
DEG_APCC_DBOX_1	673	681	PF00400	0.659
DEG_SCF_TRCP1_1	749	754	PF00400	0.631
DOC_CKS1_1	388	393	PF01111	0.812
DOC_CYCLIN_RxL_1	239	247	PF00134	0.503
DOC_CYCLIN_RxL_1	499	508	PF00134	0.747
DOC_MAPK_gen_1	184	191	PF00069	0.399
DOC_MAPK_gen_1	38	44	PF00069	0.550
DOC_MAPK_gen_1	668	678	PF00069	0.554
DOC_MAPK_gen_1	78	85	PF00069	0.628
DOC_MAPK_MEF2A_6	184	193	PF00069	0.625
DOC_MAPK_MEF2A_6	195	203	PF00069	0.434
DOC_MAPK_MEF2A_6	38	46	PF00069	0.629
DOC_MAPK_MEF2A_6	671	680	PF00069	0.579
DOC_MAPK_NFAT4_5	39	47	PF00069	0.635
DOC_MAPK_NFAT4_5	673	681	PF00069	0.581
DOC_PP2B_LxvP_1	143	146	PF13499	0.718
DOC_PP2B_LxvP_1	286	289	PF13499	0.860
DOC_PP2B_LxvP_1	416	419	PF13499	0.780
DOC_PP2B_LxvP_1	844	847	PF13499	0.699
DOC_PP4_FxxP_1	228	231	PF00568	0.663
DOC_USP7_MATH_1	106	110	PF00917	0.710
DOC_USP7_MATH_1	119	123	PF00917	0.514
DOC_USP7_MATH_1	146	150	PF00917	0.839
DOC_USP7_MATH_1	163	167	PF00917	0.540
DOC_USP7_MATH_1	408	412	PF00917	0.789
DOC_USP7_MATH_1	445	449	PF00917	0.705
DOC_USP7_MATH_1	471	475	PF00917	0.760
DOC_USP7_MATH_1	500	504	PF00917	0.759
DOC_USP7_MATH_1	517	521	PF00917	0.603
DOC_USP7_MATH_1	553	557	PF00917	0.627
DOC_USP7_MATH_1	568	572	PF00917	0.420
DOC_USP7_MATH_1	649	653	PF00917	0.642
DOC_USP7_MATH_1	747	751	PF00917	0.733
DOC_USP7_MATH_1	758	762	PF00917	0.595
DOC_USP7_MATH_1	780	784	PF00917	0.734
DOC_USP7_UBL2_3	39	43	PF12436	0.627
DOC_WW_Pin1_4	129	134	PF00397	0.578
DOC_WW_Pin1_4	27	32	PF00397	0.718
DOC_WW_Pin1_4	284	289	PF00397	0.786
DOC_WW_Pin1_4	291	296	PF00397	0.607
DOC_WW_Pin1_4	351	356	PF00397	0.660
DOC_WW_Pin1_4	366	371	PF00397	0.755
DOC_WW_Pin1_4	381	386	PF00397	0.628
DOC_WW_Pin1_4	387	392	PF00397	0.698
DOC_WW_Pin1_4	404	409	PF00397	0.661
DOC_WW_Pin1_4	489	494	PF00397	0.606
DOC_WW_Pin1_4	724	729	PF00397	0.611
DOC_WW_Pin1_4	743	748	PF00397	0.815
DOC_WW_Pin1_4	776	781	PF00397	0.790
DOC_WW_Pin1_4	797	802	PF00397	0.668
LIG_14-3-3_CanoR_1	140	144	PF00244	0.617
LIG_14-3-3_CanoR_1	3	7	PF00244	0.585
LIG_14-3-3_CanoR_1	329	333	PF00244	0.658
LIG_14-3-3_CanoR_1	376	385	PF00244	0.790
LIG_14-3-3_CanoR_1	441	449	PF00244	0.690
LIG_14-3-3_CanoR_1	458	466	PF00244	0.717
LIG_14-3-3_CanoR_1	501	505	PF00244	0.749
LIG_14-3-3_CanoR_1	561	567	PF00244	0.571
LIG_14-3-3_CanoR_1	610	614	PF00244	0.537
LIG_14-3-3_CanoR_1	650	658	PF00244	0.575
LIG_14-3-3_CanoR_1	732	740	PF00244	0.823
LIG_14-3-3_CanoR_1	757	767	PF00244	0.741
LIG_14-3-3_CanoR_1	82	86	PF00244	0.544
LIG_14-3-3_CanoR_1	834	840	PF00244	0.707
LIG_14-3-3_CanoR_1	871	875	PF00244	0.805
LIG_APCC_ABBAyCdc20_2	501	507	PF00400	0.749
LIG_BIR_II_1	1	5	PF00653	0.707
LIG_BIR_III_4	157	161	PF00653	0.716
LIG_CaM_IQ_9	655	670	PF13499	0.537
LIG_FHA_1	188	194	PF00498	0.514
LIG_FHA_1	222	228	PF00498	0.541
LIG_FHA_1	444	450	PF00498	0.789
LIG_FHA_1	510	516	PF00498	0.682
LIG_FHA_1	70	76	PF00498	0.621
LIG_FHA_1	827	833	PF00498	0.833
LIG_FHA_2	170	176	PF00498	0.581
LIG_FHA_2	3	9	PF00498	0.704
LIG_FHA_2	422	428	PF00498	0.629
LIG_FHA_2	458	464	PF00498	0.658
LIG_FHA_2	492	498	PF00498	0.811
LIG_FHA_2	587	593	PF00498	0.657
LIG_FHA_2	840	846	PF00498	0.589
LIG_LIR_Apic_2	364	370	PF02991	0.763
LIG_LIR_Apic_2	386	391	PF02991	0.713
LIG_LIR_Apic_2	752	758	PF02991	0.650
LIG_LIR_Gen_1	125	133	PF02991	0.713
LIG_LIR_Gen_1	60	71	PF02991	0.638
LIG_LIR_LC3C_4	52	56	PF02991	0.414
LIG_LIR_Nem_3	125	130	PF02991	0.720
LIG_LIR_Nem_3	60	66	PF02991	0.605
LIG_NBox_RRM_1	212	222	PF00076	0.553
LIG_PDZ_Class_1	870	875	PF00595	0.808
LIG_Pex14_2	127	131	PF04695	0.680
LIG_PTAP_UEV_1	294	299	PF05743	0.871
LIG_RPA_C_Fungi	190	202	PF08784	0.376
LIG_SH2_NCK_1	358	362	PF00017	0.629
LIG_SH2_NCK_1	470	474	PF00017	0.625
LIG_SH2_PTP2	63	66	PF00017	0.602
LIG_SH2_SRC	358	361	PF00017	0.670
LIG_SH2_STAP1	647	651	PF00017	0.638
LIG_SH2_STAT3	710	713	PF00017	0.726
LIG_SH2_STAT5	36	39	PF00017	0.643
LIG_SH2_STAT5	4	7	PF00017	0.701
LIG_SH2_STAT5	63	66	PF00017	0.602
LIG_SH2_STAT5	839	842	PF00017	0.828
LIG_SH2_STAT5	867	870	PF00017	0.743
LIG_SH3_1	400	406	PF00018	0.870
LIG_SH3_1	788	794	PF00018	0.621
LIG_SH3_2	490	495	PF14604	0.607
LIG_SH3_3	115	121	PF00018	0.771
LIG_SH3_3	127	133	PF00018	0.485
LIG_SH3_3	233	239	PF00018	0.503
LIG_SH3_3	250	256	PF00018	0.645
LIG_SH3_3	286	292	PF00018	0.865
LIG_SH3_3	295	301	PF00018	0.722
LIG_SH3_3	347	353	PF00018	0.777
LIG_SH3_3	354	360	PF00018	0.695
LIG_SH3_3	399	405	PF00018	0.737
LIG_SH3_3	479	485	PF00018	0.819
LIG_SH3_3	487	493	PF00018	0.706
LIG_SH3_3	511	517	PF00018	0.652
LIG_SH3_3	61	67	PF00018	0.613
LIG_SH3_3	741	747	PF00018	0.812
LIG_SH3_3	774	780	PF00018	0.707
LIG_SH3_3	788	794	PF00018	0.588
LIG_SH3_3	845	851	PF00018	0.734
LIG_SUMO_SIM_anti_2	52	60	PF11976	0.410
LIG_SUMO_SIM_par_1	52	60	PF11976	0.521
LIG_SUMO_SIM_par_1	570	578	PF11976	0.569
LIG_TRAF2_1	231	234	PF00917	0.733
LIG_TRAF2_1	280	283	PF00917	0.784
LIG_TRAF2_1	361	364	PF00917	0.827
LIG_TRAF2_1	460	463	PF00917	0.653
LIG_TRAF2_1	643	646	PF00917	0.631
LIG_WW_1	847	850	PF00397	0.732
LIG_WW_3	287	291	PF00397	0.864
LIG_WW_3	789	793	PF00397	0.734
MOD_CDC14_SPxK_1	287	290	PF00782	0.721
MOD_CDC14_SPxK_1	392	395	PF00782	0.864
MOD_CDC14_SPxK_1	492	495	PF00782	0.608
MOD_CDK_SPK_2	129	134	PF00069	0.551
MOD_CDK_SPK_2	288	293	PF00069	0.708
MOD_CDK_SPK_2	743	748	PF00069	0.815
MOD_CDK_SPxK_1	284	290	PF00069	0.790
MOD_CDK_SPxK_1	389	395	PF00069	0.866
MOD_CDK_SPxK_1	489	495	PF00069	0.608
MOD_CK1_1	122	128	PF00069	0.657
MOD_CK1_1	129	135	PF00069	0.702
MOD_CK1_1	2	8	PF00069	0.702
MOD_CK1_1	220	226	PF00069	0.592
MOD_CK1_1	291	297	PF00069	0.789
MOD_CK1_1	315	321	PF00069	0.832
MOD_CK1_1	328	334	PF00069	0.637
MOD_CK1_1	380	386	PF00069	0.649
MOD_CK1_1	443	449	PF00069	0.788
MOD_CK1_1	454	460	PF00069	0.651
MOD_CK1_1	520	526	PF00069	0.818
MOD_CK1_1	602	608	PF00069	0.424
MOD_CK1_1	750	756	PF00069	0.758
MOD_CK1_1	783	789	PF00069	0.750
MOD_CK1_1	796	802	PF00069	0.610
MOD_CK2_1	169	175	PF00069	0.580
MOD_CK2_1	2	8	PF00069	0.702
MOD_CK2_1	441	447	PF00069	0.656
MOD_CK2_1	457	463	PF00069	0.581
MOD_CK2_1	480	486	PF00069	0.668
MOD_CK2_1	491	497	PF00069	0.678
MOD_CK2_1	586	592	PF00069	0.659
MOD_CK2_1	602	608	PF00069	0.393
MOD_CK2_1	758	764	PF00069	0.735
MOD_CK2_1	839	845	PF00069	0.592
MOD_Cter_Amidation	182	185	PF01082	0.558
MOD_GlcNHglycan	106	109	PF01048	0.784
MOD_GlcNHglycan	12	15	PF01048	0.770
MOD_GlcNHglycan	121	124	PF01048	0.543
MOD_GlcNHglycan	152	155	PF01048	0.774
MOD_GlcNHglycan	165	168	PF01048	0.576
MOD_GlcNHglycan	204	207	PF01048	0.643
MOD_GlcNHglycan	246	249	PF01048	0.634
MOD_GlcNHglycan	311	315	PF01048	0.822
MOD_GlcNHglycan	385	388	PF01048	0.692
MOD_GlcNHglycan	416	419	PF01048	0.837
MOD_GlcNHglycan	443	446	PF01048	0.696
MOD_GlcNHglycan	474	477	PF01048	0.817
MOD_GlcNHglycan	522	525	PF01048	0.674
MOD_GlcNHglycan	555	558	PF01048	0.649
MOD_GlcNHglycan	601	604	PF01048	0.418
MOD_GlcNHglycan	651	654	PF01048	0.570
MOD_GlcNHglycan	67	70	PF01048	0.610
MOD_GlcNHglycan	736	739	PF01048	0.833
MOD_GlcNHglycan	749	752	PF01048	0.732
MOD_GlcNHglycan	761	764	PF01048	0.611
MOD_GlcNHglycan	768	771	PF01048	0.572
MOD_GlcNHglycan	802	805	PF01048	0.820
MOD_GSK3_1	122	129	PF00069	0.687
MOD_GSK3_1	146	153	PF00069	0.822
MOD_GSK3_1	217	224	PF00069	0.551
MOD_GSK3_1	23	30	PF00069	0.722
MOD_GSK3_1	284	291	PF00069	0.705
MOD_GSK3_1	324	331	PF00069	0.752
MOD_GSK3_1	362	369	PF00069	0.792
MOD_GSK3_1	377	384	PF00069	0.690
MOD_GSK3_1	389	396	PF00069	0.621
MOD_GSK3_1	404	411	PF00069	0.681
MOD_GSK3_1	441	448	PF00069	0.809
MOD_GSK3_1	454	461	PF00069	0.673
MOD_GSK3_1	65	72	PF00069	0.662
MOD_GSK3_1	739	746	PF00069	0.725
MOD_GSK3_1	747	754	PF00069	0.672
MOD_GSK3_1	766	773	PF00069	0.597
MOD_GSK3_1	776	783	PF00069	0.750
MOD_GSK3_1	793	800	PF00069	0.578
MOD_GSK3_1	835	842	PF00069	0.701
MOD_GSK3_1	861	868	PF00069	0.745
MOD_LATS_1	310	316	PF00433	0.754
MOD_LATS_1	439	445	PF00433	0.747
MOD_N-GLC_1	10	15	PF02516	0.782
MOD_NEK2_1	126	131	PF00069	0.798
MOD_NEK2_1	414	419	PF00069	0.823
MOD_NEK2_1	46	51	PF00069	0.666
MOD_NEK2_1	509	514	PF00069	0.619
MOD_NEK2_1	562	567	PF00069	0.646
MOD_NEK2_1	586	591	PF00069	0.515
MOD_NEK2_2	421	426	PF00069	0.742
MOD_NEK2_2	445	450	PF00069	0.868
MOD_NEK2_2	500	505	PF00069	0.748
MOD_OFUCOSY	478	484	PF10250	0.704
MOD_PIKK_1	408	414	PF00454	0.792
MOD_PIKK_1	458	464	PF00454	0.736
MOD_PIKK_1	509	515	PF00454	0.697
MOD_PIKK_1	602	608	PF00454	0.657
MOD_PIKK_1	783	789	PF00454	0.633
MOD_PKA_1	184	190	PF00069	0.406
MOD_PKA_1	217	223	PF00069	0.573
MOD_PKA_2	139	145	PF00069	0.615
MOD_PKA_2	184	190	PF00069	0.406
MOD_PKA_2	2	8	PF00069	0.585
MOD_PKA_2	328	334	PF00069	0.769
MOD_PKA_2	440	446	PF00069	0.695
MOD_PKA_2	457	463	PF00069	0.616
MOD_PKA_2	500	506	PF00069	0.748
MOD_PKA_2	609	615	PF00069	0.592
MOD_PKA_2	649	655	PF00069	0.568
MOD_PKA_2	733	739	PF00069	0.828
MOD_PKA_2	747	753	PF00069	0.585
MOD_PKA_2	81	87	PF00069	0.562
MOD_PKB_1	322	330	PF00069	0.791
MOD_PKB_1	732	740	PF00069	0.753
MOD_Plk_1	362	368	PF00069	0.782
MOD_Plk_1	509	515	PF00069	0.619
MOD_Plk_4	122	128	PF00069	0.723
MOD_Plk_4	184	190	PF00069	0.639
MOD_Plk_4	568	574	PF00069	0.643
MOD_Plk_4	609	615	PF00069	0.592
MOD_Plk_4	739	745	PF00069	0.605
MOD_Plk_4	780	786	PF00069	0.738
MOD_Plk_4	835	841	PF00069	0.633
MOD_ProDKin_1	129	135	PF00069	0.580
MOD_ProDKin_1	27	33	PF00069	0.708
MOD_ProDKin_1	284	290	PF00069	0.790
MOD_ProDKin_1	291	297	PF00069	0.606
MOD_ProDKin_1	351	357	PF00069	0.664
MOD_ProDKin_1	366	372	PF00069	0.757
MOD_ProDKin_1	381	387	PF00069	0.629
MOD_ProDKin_1	389	395	PF00069	0.671
MOD_ProDKin_1	404	410	PF00069	0.695
MOD_ProDKin_1	489	495	PF00069	0.608
MOD_ProDKin_1	724	730	PF00069	0.610
MOD_ProDKin_1	743	749	PF00069	0.813
MOD_ProDKin_1	776	782	PF00069	0.794
MOD_ProDKin_1	797	803	PF00069	0.666
TRG_DiLeu_BaEn_1	672	677	PF01217	0.649
TRG_DiLeu_BaLyEn_6	239	244	PF01217	0.593
TRG_DiLeu_BaLyEn_6	464	469	PF01217	0.752
TRG_ENDOCYTIC_2	204	207	PF00928	0.643
TRG_ENDOCYTIC_2	63	66	PF00928	0.602
TRG_ER_diArg_1	184	186	PF00400	0.466
TRG_ER_diArg_1	500	502	PF00400	0.755
TRG_ER_diArg_1	628	631	PF00400	0.495
TRG_ER_diArg_1	697	700	PF00400	0.684
TRG_ER_diArg_1	714	716	PF00400	0.481
TRG_ER_diArg_1	755	757	PF00400	0.761
TRG_ER_diArg_1	77	79	PF00400	0.643
TRG_ER_diArg_1	833	835	PF00400	0.707
TRG_Pf-PMV_PEXEL_1	502	507	PF00026	0.747
TRG_Pf-PMV_PEXEL_1	620	624	PF00026	0.604
TRG_Pf-PMV_PEXEL_1	674	679	PF00026	0.655

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WUY5	Leishmania donovani	82%	97%
A4H9K1	Leishmania braziliensis	52%	98%
A4HXW6	Leishmania infantum	82%	97%
E9ARN0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	73%	100%