Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ttaggg binding factor, putative

Species:

Leishmania major

UniProt:

Q4QDR7_LEIMA

TriTrypDb:

LmjF.18.1250 , LMJLV39_180018100 , LMJSD75_180018400 , LMJSD75_180018500

Length:

796

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QDR7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QDR7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	374	378	PF00656	0.700
CLV_C14_Caspase3-7	429	433	PF00656	0.795
CLV_C14_Caspase3-7	480	484	PF00656	0.794
CLV_C14_Caspase3-7	494	498	PF00656	0.575
CLV_C14_Caspase3-7	502	506	PF00656	0.626
CLV_C14_Caspase3-7	760	764	PF00656	0.549
CLV_NRD_NRD_1	168	170	PF00675	0.823
CLV_NRD_NRD_1	244	246	PF00675	0.743
CLV_NRD_NRD_1	278	280	PF00675	0.636
CLV_NRD_NRD_1	297	299	PF00675	0.807
CLV_NRD_NRD_1	320	322	PF00675	0.715
CLV_NRD_NRD_1	344	346	PF00675	0.819
CLV_NRD_NRD_1	520	522	PF00675	0.711
CLV_NRD_NRD_1	537	539	PF00675	0.578
CLV_NRD_NRD_1	654	656	PF00675	0.791
CLV_NRD_NRD_1	683	685	PF00675	0.808
CLV_NRD_NRD_1	739	741	PF00675	0.664
CLV_NRD_NRD_1	76	78	PF00675	0.671
CLV_PCSK_FUR_1	276	280	PF00082	0.558
CLV_PCSK_FUR_1	294	298	PF00082	0.738
CLV_PCSK_KEX2_1	168	170	PF00082	0.823
CLV_PCSK_KEX2_1	244	246	PF00082	0.603
CLV_PCSK_KEX2_1	278	280	PF00082	0.636
CLV_PCSK_KEX2_1	296	298	PF00082	0.804
CLV_PCSK_KEX2_1	320	322	PF00082	0.715
CLV_PCSK_KEX2_1	346	348	PF00082	0.819
CLV_PCSK_KEX2_1	520	522	PF00082	0.716
CLV_PCSK_KEX2_1	537	539	PF00082	0.573
CLV_PCSK_KEX2_1	654	656	PF00082	0.789
CLV_PCSK_KEX2_1	682	684	PF00082	0.827
CLV_PCSK_KEX2_1	738	740	PF00082	0.680
CLV_PCSK_KEX2_1	76	78	PF00082	0.671
CLV_PCSK_PC1ET2_1	346	348	PF00082	0.819
CLV_PCSK_PC7_1	734	740	PF00082	0.656
CLV_PCSK_SKI1_1	52	56	PF00082	0.709
CLV_PCSK_SKI1_1	529	533	PF00082	0.776
CLV_PCSK_SKI1_1	659	663	PF00082	0.690
CLV_PCSK_SKI1_1	724	728	PF00082	0.629
CLV_PCSK_SKI1_1	734	738	PF00082	0.505
CLV_PCSK_SKI1_1	755	759	PF00082	0.651
DEG_SPOP_SBC_1	289	293	PF00917	0.702
DEG_SPOP_SBC_1	354	358	PF00917	0.782
DEG_SPOP_SBC_1	460	464	PF00917	0.717
DEG_SPOP_SBC_1	573	577	PF00917	0.596
DEG_SPOP_SBC_1	583	587	PF00917	0.606
DEG_SPOP_SBC_1	643	647	PF00917	0.713
DEG_SPOP_SBC_1	674	678	PF00917	0.787
DOC_CKS1_1	776	781	PF01111	0.767
DOC_CYCLIN_yCln2_LP_2	421	427	PF00134	0.747
DOC_MAPK_gen_1	721	729	PF00069	0.633
DOC_MAPK_RevD_3	263	279	PF00069	0.531
DOC_PP2B_LxvP_1	123	126	PF13499	0.750
DOC_PP2B_LxvP_1	337	340	PF13499	0.725
DOC_PP2B_LxvP_1	421	424	PF13499	0.740
DOC_PP2B_LxvP_1	640	643	PF13499	0.699
DOC_PP2B_LxvP_1	87	90	PF13499	0.675
DOC_PP2B_PxIxI_1	142	148	PF00149	0.676
DOC_USP7_MATH_1	153	157	PF00917	0.620
DOC_USP7_MATH_1	182	186	PF00917	0.709
DOC_USP7_MATH_1	229	233	PF00917	0.673
DOC_USP7_MATH_1	264	268	PF00917	0.653
DOC_USP7_MATH_1	289	293	PF00917	0.702
DOC_USP7_MATH_1	348	352	PF00917	0.780
DOC_USP7_MATH_1	354	358	PF00917	0.750
DOC_USP7_MATH_1	359	363	PF00917	0.687
DOC_USP7_MATH_1	371	375	PF00917	0.544
DOC_USP7_MATH_1	459	463	PF00917	0.591
DOC_USP7_MATH_1	531	535	PF00917	0.710
DOC_USP7_MATH_1	539	543	PF00917	0.645
DOC_USP7_MATH_1	572	576	PF00917	0.729
DOC_USP7_MATH_1	583	587	PF00917	0.721
DOC_USP7_MATH_1	634	638	PF00917	0.736
DOC_USP7_MATH_1	644	648	PF00917	0.614
DOC_USP7_MATH_1	715	719	PF00917	0.576
DOC_USP7_MATH_1	743	747	PF00917	0.696
DOC_USP7_MATH_1	753	757	PF00917	0.604
DOC_WW_Pin1_4	126	131	PF00397	0.749
DOC_WW_Pin1_4	138	143	PF00397	0.615
DOC_WW_Pin1_4	157	162	PF00397	0.777
DOC_WW_Pin1_4	172	177	PF00397	0.571
DOC_WW_Pin1_4	178	183	PF00397	0.659
DOC_WW_Pin1_4	196	201	PF00397	0.527
DOC_WW_Pin1_4	205	210	PF00397	0.540
DOC_WW_Pin1_4	238	243	PF00397	0.806
DOC_WW_Pin1_4	350	355	PF00397	0.614
DOC_WW_Pin1_4	574	579	PF00397	0.648
DOC_WW_Pin1_4	584	589	PF00397	0.673
DOC_WW_Pin1_4	685	690	PF00397	0.680
DOC_WW_Pin1_4	769	774	PF00397	0.771
DOC_WW_Pin1_4	775	780	PF00397	0.684
DOC_WW_Pin1_4	9	14	PF00397	0.718
LIG_14-3-3_CanoR_1	100	105	PF00244	0.629
LIG_14-3-3_CanoR_1	15	25	PF00244	0.717
LIG_14-3-3_CanoR_1	236	242	PF00244	0.702
LIG_14-3-3_CanoR_1	244	254	PF00244	0.629
LIG_14-3-3_CanoR_1	347	354	PF00244	0.709
LIG_14-3-3_CanoR_1	363	371	PF00244	0.555
LIG_14-3-3_CanoR_1	475	479	PF00244	0.671
LIG_14-3-3_CanoR_1	553	558	PF00244	0.567
LIG_14-3-3_CanoR_1	584	588	PF00244	0.685
LIG_14-3-3_CanoR_1	604	612	PF00244	0.712
LIG_14-3-3_CanoR_1	659	668	PF00244	0.632
LIG_14-3-3_CanoR_1	721	730	PF00244	0.633
LIG_14-3-3_CanoR_1	76	86	PF00244	0.642
LIG_BIR_II_1	1	5	PF00653	0.571
LIG_BIR_III_2	483	487	PF00653	0.793
LIG_BRCT_BRCA1_1	705	709	PF00533	0.618
LIG_BRCT_BRCA1_1	94	98	PF00533	0.625
LIG_FHA_1	118	124	PF00498	0.728
LIG_FHA_1	36	42	PF00498	0.615
LIG_FHA_1	365	371	PF00498	0.653
LIG_FHA_1	390	396	PF00498	0.727
LIG_FHA_1	466	472	PF00498	0.708
LIG_FHA_1	588	594	PF00498	0.817
LIG_FHA_1	614	620	PF00498	0.699
LIG_FHA_1	624	630	PF00498	0.629
LIG_FHA_1	676	682	PF00498	0.796
LIG_FHA_2	101	107	PF00498	0.648
LIG_FHA_2	209	215	PF00498	0.653
LIG_FHA_2	615	621	PF00498	0.633
LIG_GBD_Chelix_1	109	117	PF00786	0.629
LIG_Integrin_RGD_1	43	45	PF01839	0.695
LIG_LIR_Apic_2	410	416	PF02991	0.672
LIG_LIR_Apic_2	528	533	PF02991	0.824
LIG_LIR_Gen_1	706	716	PF02991	0.606
LIG_LIR_Nem_3	60	66	PF02991	0.676
LIG_LIR_Nem_3	706	712	PF02991	0.609
LIG_MYND_1	671	675	PF01753	0.643
LIG_NRBOX	214	220	PF00104	0.702
LIG_NRBOX	264	270	PF00104	0.728
LIG_SH2_GRB2like	413	416	PF00017	0.748
LIG_SH2_PTP2	413	416	PF00017	0.748
LIG_SH2_SRC	413	416	PF00017	0.748
LIG_SH2_STAT5	314	317	PF00017	0.723
LIG_SH2_STAT5	413	416	PF00017	0.748
LIG_SH2_STAT5	63	66	PF00017	0.657
LIG_SH2_STAT5	711	714	PF00017	0.598
LIG_SH3_1	168	174	PF00018	0.780
LIG_SH3_1	770	776	PF00018	0.772
LIG_SH3_3	168	174	PF00018	0.747
LIG_SH3_3	181	187	PF00018	0.653
LIG_SH3_3	236	242	PF00018	0.807
LIG_SH3_3	568	574	PF00018	0.580
LIG_SH3_3	575	581	PF00018	0.592
LIG_SH3_3	627	633	PF00018	0.628
LIG_SH3_3	63	69	PF00018	0.643
LIG_SH3_3	665	671	PF00018	0.776
LIG_SH3_3	770	776	PF00018	0.817
LIG_SUMO_SIM_anti_2	514	520	PF11976	0.682
LIG_SUMO_SIM_par_1	208	214	PF11976	0.663
LIG_SUMO_SIM_par_1	37	42	PF11976	0.578
LIG_SUMO_SIM_par_1	68	73	PF11976	0.621
LIG_SUMO_SIM_par_1	80	88	PF11976	0.376
LIG_SxIP_EBH_1	363	376	PF03271	0.666
LIG_TRAF2_1	426	429	PF00917	0.735
LIG_TRAF2_1	688	691	PF00917	0.639
LIG_TYR_ITIM	61	66	PF00017	0.669
LIG_WRC_WIRS_1	132	137	PF05994	0.574
MOD_CDC14_SPxK_1	241	244	PF00782	0.595
MOD_CDC14_SPxK_1	577	580	PF00782	0.586
MOD_CDK_SPK_2	201	206	PF00069	0.719
MOD_CDK_SPxK_1	238	244	PF00069	0.597
MOD_CDK_SPxK_1	574	580	PF00069	0.577
MOD_CDK_SPxK_1	9	15	PF00069	0.640
MOD_CDK_SPxxK_3	161	168	PF00069	0.763
MOD_CDK_SPxxK_3	238	245	PF00069	0.738
MOD_CK1_1	128	134	PF00069	0.817
MOD_CK1_1	172	178	PF00069	0.768
MOD_CK1_1	185	191	PF00069	0.609
MOD_CK1_1	199	205	PF00069	0.783
MOD_CK1_1	238	244	PF00069	0.807
MOD_CK1_1	247	253	PF00069	0.677
MOD_CK1_1	280	286	PF00069	0.808
MOD_CK1_1	350	356	PF00069	0.735
MOD_CK1_1	357	363	PF00069	0.779
MOD_CK1_1	37	43	PF00069	0.739
MOD_CK1_1	430	436	PF00069	0.845
MOD_CK1_1	446	452	PF00069	0.781
MOD_CK1_1	462	468	PF00069	0.558
MOD_CK1_1	576	582	PF00069	0.699
MOD_CK1_1	586	592	PF00069	0.725
MOD_CK1_1	622	628	PF00069	0.690
MOD_CK1_1	676	682	PF00069	0.792
MOD_CK1_1	88	94	PF00069	0.636
MOD_CK2_1	100	106	PF00069	0.460
MOD_CK2_1	553	559	PF00069	0.566
MOD_CK2_1	614	620	PF00069	0.647
MOD_CK2_1	685	691	PF00069	0.628
MOD_CK2_1	784	790	PF00069	0.764
MOD_CK2_1	88	94	PF00069	0.652
MOD_DYRK1A_RPxSP_1	157	161	PF00069	0.638
MOD_DYRK1A_RPxSP_1	584	588	PF00069	0.601
MOD_GlcNHglycan	19	22	PF01048	0.593
MOD_GlcNHglycan	249	252	PF01048	0.799
MOD_GlcNHglycan	357	360	PF01048	0.810
MOD_GlcNHglycan	373	376	PF01048	0.608
MOD_GlcNHglycan	45	49	PF01048	0.667
MOD_GlcNHglycan	509	512	PF01048	0.601
MOD_GlcNHglycan	525	528	PF01048	0.562
MOD_GlcNHglycan	533	536	PF01048	0.672
MOD_GlcNHglycan	541	544	PF01048	0.577
MOD_GlcNHglycan	605	608	PF01048	0.711
MOD_GlcNHglycan	620	624	PF01048	0.529
MOD_GlcNHglycan	640	643	PF01048	0.563
MOD_GlcNHglycan	646	649	PF01048	0.606
MOD_GlcNHglycan	662	665	PF01048	0.631
MOD_GlcNHglycan	7	10	PF01048	0.758
MOD_GlcNHglycan	705	708	PF01048	0.675
MOD_GlcNHglycan	745	748	PF01048	0.553
MOD_GlcNHglycan	754	758	PF01048	0.566
MOD_GSK3_1	1	8	PF00069	0.785
MOD_GSK3_1	117	124	PF00069	0.698
MOD_GSK3_1	126	133	PF00069	0.636
MOD_GSK3_1	134	141	PF00069	0.529
MOD_GSK3_1	153	160	PF00069	0.802
MOD_GSK3_1	174	181	PF00069	0.771
MOD_GSK3_1	201	208	PF00069	0.787
MOD_GSK3_1	277	284	PF00069	0.817
MOD_GSK3_1	348	355	PF00069	0.786
MOD_GSK3_1	35	42	PF00069	0.608
MOD_GSK3_1	365	372	PF00069	0.591
MOD_GSK3_1	427	434	PF00069	0.828
MOD_GSK3_1	442	449	PF00069	0.791
MOD_GSK3_1	461	468	PF00069	0.506
MOD_GSK3_1	553	560	PF00069	0.771
MOD_GSK3_1	572	579	PF00069	0.592
MOD_GSK3_1	582	589	PF00069	0.665
MOD_GSK3_1	619	626	PF00069	0.751
MOD_GSK3_1	634	641	PF00069	0.644
MOD_GSK3_1	743	750	PF00069	0.690
MOD_GSK3_1	88	95	PF00069	0.637
MOD_N-GLC_1	449	454	PF02516	0.815
MOD_NEK2_1	1	6	PF00069	0.566
MOD_NEK2_1	117	122	PF00069	0.692
MOD_NEK2_1	442	447	PF00069	0.723
MOD_NEK2_1	453	458	PF00069	0.600
MOD_NEK2_1	619	624	PF00069	0.723
MOD_NEK2_1	638	643	PF00069	0.540
MOD_NEK2_1	660	665	PF00069	0.581
MOD_NEK2_1	705	710	PF00069	0.516
MOD_NEK2_1	98	103	PF00069	0.659
MOD_PIKK_1	327	333	PF00454	0.681
MOD_PK_1	553	559	PF00069	0.566
MOD_PKA_1	244	250	PF00069	0.597
MOD_PKA_1	278	284	PF00069	0.637
MOD_PKA_1	537	543	PF00069	0.586
MOD_PKA_2	17	23	PF00069	0.832
MOD_PKA_2	235	241	PF00069	0.707
MOD_PKA_2	244	250	PF00069	0.623
MOD_PKA_2	277	283	PF00069	0.764
MOD_PKA_2	348	354	PF00069	0.777
MOD_PKA_2	474	480	PF00069	0.673
MOD_PKA_2	537	543	PF00069	0.676
MOD_PKA_2	583	589	PF00069	0.632
MOD_PKA_2	603	609	PF00069	0.733
MOD_PKB_1	276	284	PF00069	0.565
MOD_PKB_1	345	353	PF00069	0.714
MOD_Plk_1	473	479	PF00069	0.670
MOD_Plk_1	558	564	PF00069	0.561
MOD_Plk_1	753	759	PF00069	0.539
MOD_Plk_2-3	304	310	PF00069	0.541
MOD_Plk_2-3	474	480	PF00069	0.673
MOD_Plk_2-3	784	790	PF00069	0.753
MOD_Plk_4	264	270	PF00069	0.728
MOD_Plk_4	314	320	PF00069	0.733
MOD_Plk_4	365	371	PF00069	0.589
MOD_Plk_4	437	443	PF00069	0.728
MOD_ProDKin_1	126	132	PF00069	0.750
MOD_ProDKin_1	138	144	PF00069	0.616
MOD_ProDKin_1	157	163	PF00069	0.776
MOD_ProDKin_1	172	178	PF00069	0.565
MOD_ProDKin_1	196	202	PF00069	0.779
MOD_ProDKin_1	205	211	PF00069	0.531
MOD_ProDKin_1	238	244	PF00069	0.807
MOD_ProDKin_1	350	356	PF00069	0.615
MOD_ProDKin_1	574	580	PF00069	0.653
MOD_ProDKin_1	584	590	PF00069	0.673
MOD_ProDKin_1	685	691	PF00069	0.666
MOD_ProDKin_1	769	775	PF00069	0.771
MOD_ProDKin_1	9	15	PF00069	0.722
TRG_DiLeu_BaLyEn_6	49	54	PF01217	0.654
TRG_ENDOCYTIC_2	63	66	PF00928	0.657
TRG_ENDOCYTIC_2	716	719	PF00928	0.561
TRG_ER_diArg_1	275	278	PF00400	0.555
TRG_ER_diArg_1	294	297	PF00400	0.797
TRG_ER_diArg_1	319	321	PF00400	0.709
TRG_ER_diArg_1	345	348	PF00400	0.815
TRG_ER_diArg_1	519	521	PF00400	0.676
TRG_ER_diArg_1	681	684	PF00400	0.821
TRG_ER_diArg_1	737	740	PF00400	0.658
TRG_ER_diArg_1	75	77	PF00400	0.653
TRG_NLS_MonoCore_2	345	350	PF00514	0.821
TRG_NLS_MonoExtC_3	344	349	PF00514	0.819
TRG_NLS_MonoExtN_4	345	350	PF00514	0.818
TRG_Pf-PMV_PEXEL_1	273	277	PF00026	0.539

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IB42	Leishmania donovani	89%	100%
A4H9N4	Leishmania braziliensis	66%	98%
A4HXZ8	Leishmania infantum	89%	100%
E9ARR2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%