ADP/ATP translocase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

ADP/ATP translocase

Gene product:

ADP,ATP carrier protein 1, mitochondrial precursor, putative

Species:

Leishmania major

UniProt:

Q4QDK0_LEIMA

TriTrypDb:

LmjF.19.0210 , LMJLV39_190006900 , LMJSD75_190006900

Length:

317

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 4
Forrest at al. (procyclic)	no	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 21

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	yes	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 10

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 14
NetGPI	no	yes: 0, no: 14

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	2
GO:0005743	mitochondrial inner membrane	5	15
GO:0016020	membrane	2	15
GO:0019866	organelle inner membrane	4	15
GO:0031090	organelle membrane	3	15
GO:0031966	mitochondrial membrane	4	15
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	15

Expansion

Sequence features

Q4QDK0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QDK0

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	15
GO:0006811	monoatomic ion transport	4	15
GO:0006820	monoatomic anion transport	5	15
GO:0006862	nucleotide transport	6	15
GO:0009987	cellular process	1	15
GO:0015711	organic anion transport	5	15
GO:0015748	organophosphate ester transport	5	15
GO:0015865	purine nucleotide transport	7	15
GO:0015866	ADP transport	6	15
GO:0015867	ATP transport	6	15
GO:0015868	purine ribonucleotide transport	6	15
GO:0015931	nucleobase-containing compound transport	5	15
GO:0034220	monoatomic ion transmembrane transport	3	15
GO:0051179	localization	1	15
GO:0051234	establishment of localization	2	15
GO:0051503	adenine nucleotide transport	8	15
GO:0055085	transmembrane transport	2	15
GO:0071702	organic substance transport	4	15
GO:0071705	nitrogen compound transport	4	15
GO:0072530	purine-containing compound transmembrane transport	3	15
GO:0098656	monoatomic anion transmembrane transport	4	15
GO:0140021	mitochondrial ADP transmembrane transport	4	15
GO:1901264	carbohydrate derivative transport	5	15
GO:1901679	nucleotide transmembrane transport	3	15
GO:1990542	mitochondrial transmembrane transport	3	15
GO:1990544	mitochondrial ATP transmembrane transport	4	15

Molecular functions
Term	Name	Level	Count
GO:0000295	adenine nucleotide transmembrane transporter activity	6	15
GO:0005215	transporter activity	1	15
GO:0005346	purine ribonucleotide transmembrane transporter activity	4	15
GO:0005347	ATP transmembrane transporter activity	5	15
GO:0005471	ATP:ADP antiporter activity	5	15
GO:0008509	monoatomic anion transmembrane transporter activity	4	15
GO:0008514	organic anion transmembrane transporter activity	5	15
GO:0015075	monoatomic ion transmembrane transporter activity	3	15
GO:0015215	nucleotide transmembrane transporter activity	4	15
GO:0015216	purine nucleotide transmembrane transporter activity	5	15
GO:0015217	ADP transmembrane transporter activity	5	15
GO:0015291	secondary active transmembrane transporter activity	4	15
GO:0015297	antiporter activity	5	15
GO:0015605	organophosphate ester transmembrane transporter activity	3	15
GO:0015932	nucleobase-containing compound transmembrane transporter activity	3	15
GO:0022804	active transmembrane transporter activity	3	15
GO:0022853	active monoatomic ion transmembrane transporter activity	4	15
GO:0022857	transmembrane transporter activity	2	15
GO:0140323	obsolete solute:monoatomic anion antiporter activity	6	15
GO:1901505	carbohydrate derivative transmembrane transporter activity	3	15

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	300	304	PF00656	0.390
CLV_NRD_NRD_1	250	252	PF00675	0.320
CLV_PCSK_KEX2_1	112	114	PF00082	0.376
CLV_PCSK_KEX2_1	249	251	PF00082	0.370
CLV_PCSK_PC1ET2_1	112	114	PF00082	0.376
CLV_PCSK_SKI1_1	112	116	PF00082	0.376
CLV_PCSK_SKI1_1	161	165	PF00082	0.317
CLV_PCSK_SKI1_1	180	184	PF00082	0.357
CLV_PCSK_SKI1_1	313	317	PF00082	0.647
CLV_PCSK_SKI1_1	76	80	PF00082	0.379
DEG_APCC_DBOX_1	87	95	PF00400	0.525
DEG_MDM2_SWIB_1	228	236	PF02201	0.376
DOC_MAPK_gen_1	180	190	PF00069	0.550
DOC_MAPK_MEF2A_6	15	23	PF00069	0.428
DOC_PP1_RVXF_1	18	24	PF00149	0.323
DOC_USP7_UBL2_3	108	112	PF12436	0.376
DOC_USP7_UBL2_3	161	165	PF12436	0.535
LIG_14-3-3_CanoR_1	263	267	PF00244	0.572
LIG_14-3-3_CanoR_1	76	86	PF00244	0.532
LIG_AP2alpha_1	107	111	PF02296	0.376
LIG_BIR_II_1	1	5	PF00653	0.575
LIG_BRCT_BRCA1_1	141	145	PF00533	0.376
LIG_FHA_1	182	188	PF00498	0.573
LIG_FHA_1	73	79	PF00498	0.552
LIG_FHA_1	98	104	PF00498	0.384
LIG_LIR_Nem_3	64	70	PF02991	0.525
LIG_LYPXL_SIV_4	66	74	PF13949	0.616
LIG_Pex14_2	107	111	PF04695	0.376
LIG_Pex14_2	224	228	PF04695	0.325
LIG_Pex14_2	23	27	PF04695	0.323
LIG_SH2_CRK	212	216	PF00017	0.325
LIG_SH2_CRK	67	71	PF00017	0.525
LIG_SH2_STAP1	147	151	PF00017	0.376
LIG_SH2_STAT5	151	154	PF00017	0.376
LIG_SH2_STAT5	178	181	PF00017	0.525
LIG_SH2_STAT5	208	211	PF00017	0.376
LIG_SH2_STAT5	309	312	PF00017	0.390
LIG_SH2_STAT5	97	100	PF00017	0.376
LIG_SH3_3	214	220	PF00018	0.325
LIG_SUMO_SIM_par_1	232	238	PF11976	0.497
LIG_WRC_WIRS_1	179	184	PF05994	0.616
MOD_GlcNHglycan	1	4	PF01048	0.832
MOD_GlcNHglycan	133	136	PF01048	0.525
MOD_GlcNHglycan	161	164	PF01048	0.329
MOD_GlcNHglycan	171	174	PF01048	0.329
MOD_GlcNHglycan	237	240	PF01048	0.504
MOD_GlcNHglycan	255	258	PF01048	0.325
MOD_GlcNHglycan	29	32	PF01048	0.503
MOD_GlcNHglycan	299	302	PF01048	0.377
MOD_GlcNHglycan	310	313	PF01048	0.596
MOD_GlcNHglycan	6	9	PF01048	0.823
MOD_GlcNHglycan	67	70	PF01048	0.373
MOD_GSK3_1	235	242	PF00069	0.473
MOD_N-GLC_1	157	162	PF02516	0.325
MOD_N-GLC_1	4	9	PF02516	0.827
MOD_N-GLC_1	89	94	PF02516	0.376
MOD_NEK2_1	194	199	PF00069	0.376
MOD_NEK2_1	211	216	PF00069	0.376
MOD_NEK2_1	252	257	PF00069	0.525
MOD_NEK2_1	27	32	PF00069	0.484
MOD_NEK2_1	297	302	PF00069	0.499
MOD_NEK2_1	74	79	PF00069	0.525
MOD_NEK2_2	178	183	PF00069	0.593
MOD_NEK2_2	244	249	PF00069	0.376
MOD_NEK2_2	277	282	PF00069	0.588
MOD_PIKK_1	97	103	PF00454	0.376
MOD_PKA_2	262	268	PF00069	0.622
MOD_Plk_4	232	238	PF00069	0.427
MOD_Plk_4	277	283	PF00069	0.549
MOD_SUMO_for_1	273	276	PF00179	0.525
MOD_SUMO_for_1	78	81	PF00179	0.574
TRG_DiLeu_BaEn_1	45	50	PF01217	0.523
TRG_ENDOCYTIC_2	171	174	PF00928	0.599
TRG_ENDOCYTIC_2	191	194	PF00928	0.373
TRG_ENDOCYTIC_2	204	207	PF00928	0.376
TRG_ENDOCYTIC_2	208	211	PF00928	0.376
TRG_ENDOCYTIC_2	212	215	PF00928	0.325
TRG_ENDOCYTIC_2	67	70	PF00928	0.525
TRG_ER_diArg_1	152	155	PF00400	0.376
TRG_ER_diArg_1	248	251	PF00400	0.376
TRG_NLS_MonoExtC_3	11	17	PF00514	0.544
TRG_NLS_MonoExtN_4	11	16	PF00514	0.549

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0G2K5L2	Rattus norvegicus	23%	98%
A0A0N0P222	Leptomonas seymouri	89%	98%
A0A0N0P7T5	Leptomonas seymouri	22%	94%
A0A0N0P7X0	Leptomonas seymouri	23%	100%
A0A0N0P7Y4	Leptomonas seymouri	23%	100%
A0A0N1I6I9	Leptomonas seymouri	21%	100%
A0A0N1P9L0	Leptomonas seymouri	24%	92%
A0A0N1PD69	Leptomonas seymouri	21%	87%
A0A0S4IU86	Bodo saltans	31%	100%
A0A0S4IYL3	Bodo saltans	77%	99%
A0A0S4IZ65	Bodo saltans	39%	100%
A0A0S4IZG7	Bodo saltans	26%	91%
A0A0S4J045	Bodo saltans	24%	89%
A0A0S4J2G4	Bodo saltans	24%	92%
A0A0S4JDA7	Bodo saltans	25%	87%
A0A0S4JM95	Bodo saltans	22%	100%
A0A0S4JN82	Bodo saltans	24%	100%
A0A0U2IR85	Ustilago maydis	24%	100%
A0A1D6N272	Zea mays	24%	94%
A0A1X0NLW7	Trypanosomatidae	22%	100%
A0A1X0NPW5	Trypanosomatidae	29%	95%
A0A1X0NQ13	Trypanosomatidae	24%	98%
A0A1X0P6F0	Trypanosomatidae	80%	100%
A0A1X0P6P9	Trypanosomatidae	81%	100%
A0A1X0P778	Trypanosomatidae	25%	96%
A0A1X0PA63	Trypanosomatidae	25%	82%
A0A3Q8IB56	Leishmania donovani	99%	100%
A0A3R7K844	Trypanosoma rangeli	79%	100%
A0A3R7KEL4	Trypanosoma rangeli	29%	97%
A0A3R7KGU8	Trypanosoma rangeli	25%	94%
A0A3R7M893	Trypanosoma rangeli	24%	100%
A0A3S5H5Y3	Leishmania donovani	27%	87%
A0A3S5H7M7	Leishmania donovani	22%	94%
A0A3S7WTS6	Leishmania donovani	26%	100%
A0A3S7WVJ8	Leishmania donovani	24%	92%
A0A3S7WYS1	Leishmania donovani	23%	100%
A0A3S7X2U2	Leishmania donovani	20%	100%
A0A422N466	Trypanosoma rangeli	23%	97%
A0JN87	Bos taurus	22%	100%
A0PC02	Ochotona dauurica	25%	100%
A1CIF6	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	22%	95%
A1CWA4	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	23%	96%
A1DI57	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	25%	100%
A2A3V2	Mus musculus	27%	93%
A2ADF7	Mus musculus	24%	100%
A2ASZ8	Mus musculus	28%	68%
A2CEQ0	Danio rerio	29%	68%
A2R5A0	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	24%	99%
A3KPP4	Danio rerio	26%	100%
A3LVX1	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	25%	100%
A4H503	Leishmania braziliensis	26%	88%
A4H8E6	Leishmania braziliensis	28%	100%
A4H9N5	Leishmania braziliensis	24%	100%
A4H9N6	Leishmania braziliensis	24%	100%
A4H9X7	Leishmania braziliensis	93%	99%
A4H9X8	Leishmania braziliensis	91%	99%
A4HA67	Leishmania braziliensis	24%	92%
A4HDW8	Leishmania braziliensis	22%	100%
A4HT75	Leishmania infantum	27%	87%
A4HWR9	Leishmania infantum	26%	100%
A4HY43	Leishmania infantum	99%	100%
A4HYC8	Leishmania infantum	24%	92%
A4I163	Leishmania infantum	23%	100%
A4I4Z5	Leishmania infantum	20%	100%
A4I5D6	Leishmania infantum	22%	94%
A4QNX2	Danio rerio	24%	100%
A4RF23	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	22%	97%
A4RPU0	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	21%	95%
A5DIS9	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	24%	100%
A5DX39	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	27%	100%
A5PJZ1	Bos taurus	30%	66%
A6RF73	Ajellomyces capsulatus (strain NAm1 / WU24)	23%	98%
A6SL61	Botryotinia fuckeliana (strain B05.10)	25%	98%
A6ZV78	Saccharomyces cerevisiae (strain YJM789)	23%	100%
A7ER02	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	25%	98%
A7TDX5	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	27%	100%
A7TIQ0	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	22%	100%
B0G143	Dictyostelium discoideum	24%	100%
B0G159	Dictyostelium discoideum	27%	67%
B0Y4J4	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	23%	99%
B4F8I5	Zea mays	31%	95%
B4FIJ0	Zea mays	24%	94%
B8ZHC9	Rattus norvegicus	25%	100%
C9ZM27	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	82%
C9ZSY0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	96%
C9ZUP8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	95%
C9ZW54	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	100%
D0A0D8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	78%	100%
D0A0Q8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	98%
D0A9Z0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	94%
E9AL65	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	87%
E9AQH7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9ARX1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
E9ARX2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
E9AS62	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	92%
E9AX97	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
F1R4U0	Danio rerio	24%	100%
F1RFX9	Sus scrofa	23%	95%
F4HT41	Arabidopsis thaliana	22%	92%
F4HW79	Arabidopsis thaliana	29%	96%
F4JU70	Arabidopsis thaliana	29%	96%
G2QNH0	Myceliophthora thermophila (strain ATCC 42464 / BCRC 31852 / DSM 1799)	63%	100%
G5EE96	Caenorhabditis elegans	22%	100%
K7VYZ9	Zea mays	26%	93%
O04619	Arabidopsis thaliana	28%	90%
O13805	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	97%
O14281	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	100%
O18757	Oryctolagus cuniculus	28%	67%
O22342	Gossypium hirsutum	65%	82%
O43772	Homo sapiens	25%	100%
O46373	Oryctolagus cuniculus	52%	100%
O49447	Arabidopsis thaliana	67%	84%
O65023	Arabidopsis thaliana	30%	83%
O77792	Bos taurus	25%	100%
O81845	Arabidopsis thaliana	24%	100%
O89035	Rattus norvegicus	23%	100%
O94370	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
O94502	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	74%
O95258	Homo sapiens	23%	98%
O95847	Homo sapiens	23%	98%
O97470	Dictyostelium discoideum	48%	100%
O97562	Sus scrofa	25%	100%
O97649	Sus scrofa	25%	100%
P02722	Bos taurus	51%	100%
P02723	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	64%	100%
P04575	Mesocricetus auratus	25%	100%
P04633	Rattus norvegicus	24%	100%
P04709	Zea mays	65%	82%
P04710	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	57%	100%
P05141	Homo sapiens	52%	100%
P0C546	Rattus norvegicus	30%	100%
P0CAT2	Danio rerio	21%	100%
P10861	Bos taurus	25%	100%
P12235	Homo sapiens	52%	100%
P12236	Homo sapiens	50%	100%
P12242	Mus musculus	25%	100%
P12857	Zea mays	65%	82%
P14271	Oryctolagus cuniculus	25%	100%
P16260	Homo sapiens	30%	95%
P16261	Rattus norvegicus	29%	98%
P18238	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	61%	100%
P18239	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	58%	100%
P22292	Bos taurus	23%	100%
P25083	Solanum tuberosum	63%	82%
P25874	Homo sapiens	25%	100%
P27080	Chlamydomonas reinhardtii	65%	100%
P27081	Solanum tuberosum	61%	82%
P29518	Zea mays	26%	73%
P31167	Arabidopsis thaliana	65%	83%
P31691	Oryza sativa subsp. japonica	65%	83%
P31692	Parachlorella kessleri	46%	94%
P32007	Bos taurus	51%	100%
P32089	Rattus norvegicus	25%	100%
P32332	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	98%
P33303	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	98%
P34519	Caenorhabditis elegans	23%	100%
P38087	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	96%
P38127	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	21%	84%
P38152	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
P38702	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	89%
P39953	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	95%
P40556	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	85%
P40941	Arabidopsis thaliana	65%	82%
P48962	Mus musculus	52%	100%
P49382	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	62%	100%
P51881	Mus musculus	52%	100%
P53007	Homo sapiens	23%	100%
P53257	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	100%
P55851	Homo sapiens	25%	100%
P55916	Homo sapiens	24%	100%
P56499	Rattus norvegicus	24%	100%
P56500	Rattus norvegicus	24%	100%
P56501	Mus musculus	25%	100%
P70406	Mus musculus	25%	100%
P79110	Bos taurus	23%	100%
P90992	Caenorhabditis elegans	23%	100%
P97521	Rattus norvegicus	25%	100%
P97700	Rattus norvegicus	23%	100%
Q000K2	Tachyglossus aculeatus aculeatus	51%	100%
Q01888	Bos taurus	30%	96%
Q02978	Homo sapiens	23%	100%
Q03028	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	100%
Q05962	Rattus norvegicus	52%	100%
Q05AQ3	Xenopus tropicalis	29%	97%
Q06497	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	97%
Q08DK4	Bos taurus	22%	98%
Q08DK7	Bos taurus	27%	100%
Q09073	Rattus norvegicus	52%	100%
Q09188	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	65%	98%
Q0CEN9	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	24%	99%
Q0II44	Bos taurus	26%	91%
Q0P483	Danio rerio	30%	99%
Q0UUH1	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	26%	99%
Q0V7M4	Bos taurus	29%	68%
Q10248	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
Q12251	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	97%
Q18P97	Suncus murinus	23%	100%
Q1E7P0	Coccidioides immitis (strain RS)	22%	99%
Q1ECW7	Danio rerio	25%	100%
Q1LZB3	Bos taurus	23%	99%
Q26365	Drosophila melanogaster	51%	100%
Q27238	Anopheles gambiae	51%	100%
Q27257	Caenorhabditis elegans	22%	100%
Q287T7	Danio rerio	23%	95%
Q29RM1	Bos taurus	24%	100%
Q2HFL6	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	22%	98%
Q2UCW8	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	26%	100%
Q2YDD9	Bos taurus	52%	98%
Q3KQZ1	Homo sapiens	25%	100%
Q3MHI3	Bos taurus	23%	100%
Q3SZI5	Bos taurus	24%	100%
Q3SZK0	Bos taurus	24%	100%
Q3TZX3	Mus musculus	24%	99%
Q3V132	Mus musculus	50%	99%
Q41629	Triticum aestivum	64%	96%
Q41630	Triticum aestivum	63%	96%
Q4Q7J8	Leishmania major	22%	94%
Q4QA75	Leishmania major	23%	100%
Q4QDA4	Leishmania major	24%	92%
Q4QF00	Leishmania major	25%	100%
Q4QIN9	Leishmania major	27%	87%
Q4R8M0	Macaca fascicularis	51%	100%
Q4WQC5	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	23%	99%
Q4X022	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	24%	100%
Q505J6	Rattus norvegicus	24%	99%
Q54BM3	Dictyostelium discoideum	23%	100%
Q54DU1	Dictyostelium discoideum	29%	100%
Q54EV4	Dictyostelium discoideum	28%	97%
Q54FE6	Dictyostelium discoideum	25%	100%
Q54FU9	Dictyostelium discoideum	25%	96%
Q54MZ4	Dictyostelium discoideum	27%	73%
Q54PY7	Dictyostelium discoideum	22%	100%
Q54QI8	Dictyostelium discoideum	26%	97%
Q54QN2	Dictyostelium discoideum	21%	100%
Q54S10	Dictyostelium discoideum	21%	81%
Q54VS7	Dictyostelium discoideum	24%	98%
Q54VX4	Dictyostelium discoideum	20%	92%
Q54W11	Dictyostelium discoideum	23%	100%
Q55BF4	Dictyostelium discoideum	24%	100%
Q55E45	Dictyostelium discoideum	24%	100%
Q55GE2	Dictyostelium discoideum	25%	100%
Q59Q36	Candida albicans (strain SC5314 / ATCC MYA-2876)	27%	100%
Q5AVW1	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	24%	97%
Q5HZE0	Rattus norvegicus	26%	100%
Q5IS35	Macaca fascicularis	22%	99%
Q5NVC1	Pongo abelii	22%	99%
Q5PQ27	Xenopus laevis	29%	97%
Q5PQM9	Rattus norvegicus	25%	100%
Q5R5A1	Pongo abelii	51%	100%
Q5R5A8	Pongo abelii	25%	100%
Q5RD67	Pongo abelii	21%	100%
Q5RD81	Pongo abelii	22%	98%
Q5RFB7	Pongo abelii	23%	100%
Q5SVS4	Homo sapiens	24%	100%
Q5SWT3	Mus musculus	26%	100%
Q5U3V7	Danio rerio	29%	92%
Q5XGI1	Xenopus tropicalis	25%	100%
Q5XHA0	Xenopus tropicalis	29%	67%
Q5XIF9	Rattus norvegicus	23%	100%
Q5ZKP7	Gallus gallus	25%	100%
Q66L49	Danio rerio	27%	66%
Q6BPW0	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	24%	100%
Q6C107	Yarrowia lipolytica (strain CLIB 122 / E 150)	25%	94%
Q6C6I3	Yarrowia lipolytica (strain CLIB 122 / E 150)	22%	100%
Q6CNY8	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	21%	100%
Q6CQR3	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	24%	100%
Q6DE75	Xenopus laevis	22%	100%
Q6DG32	Danio rerio	25%	100%
Q6DHC3	Danio rerio	21%	90%
Q6DHS9	Danio rerio	22%	100%
Q6DJ08	Xenopus tropicalis	20%	100%
Q6FTE5	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	23%	100%
Q6FTN2	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	23%	100%
Q6GQ22	Xenopus laevis	25%	100%
Q6GQS1	Mus musculus	26%	68%
Q6IZB5	Cricetulus griseus	26%	100%
Q6KCM7	Homo sapiens	28%	68%
Q6NUK1	Homo sapiens	29%	66%
Q6NYZ6	Danio rerio	32%	68%
Q6P036	Danio rerio	25%	100%
Q6PGY3	Danio rerio	24%	88%
Q6PIV7	Homo sapiens	23%	100%
Q6QRN9	Sus scrofa	50%	100%
Q6ZT89	Homo sapiens	21%	100%
Q75A82	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	24%	93%
Q75EP3	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	26%	100%
Q76P23	Dictyostelium discoideum	21%	96%
Q7K566	Drosophila melanogaster	26%	100%
Q7PQV7	Anopheles gambiae	51%	100%
Q7S2H8	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	25%	95%
Q7T0U6	Xenopus laevis	30%	67%
Q7XA87	Arabidopsis thaliana	24%	100%
Q7ZY36	Xenopus laevis	30%	67%
Q84UC7	Arabidopsis thaliana	23%	100%
Q86AV5	Dictyostelium discoideum	26%	100%
Q86HN8	Dictyostelium discoideum	22%	73%
Q86VD7	Homo sapiens	29%	100%
Q8BGF9	Mus musculus	21%	100%
Q8BL03	Mus musculus	26%	100%
Q8BMD8	Mus musculus	30%	67%
Q8BMG8	Mus musculus	25%	100%
Q8BVN7	Mus musculus	26%	100%
Q8BW66	Mus musculus	22%	100%
Q8C0K5	Mus musculus	30%	95%
Q8CFJ7	Mus musculus	22%	100%
Q8HXE3	Macaca fascicularis	24%	100%
Q8HXY2	Macaca fascicularis	26%	100%
Q8JZU2	Mus musculus	23%	100%
Q8K3P6	Rattus norvegicus	28%	68%
Q8K404	Dicrostonyx groenlandicus	24%	100%
Q8LB08	Arabidopsis thaliana	56%	100%
Q8N413	Homo sapiens	23%	100%
Q8N5S1	Homo sapiens	26%	86%
Q8N8R3	Homo sapiens	27%	100%
Q8R0Y8	Mus musculus	30%	100%
Q8RWA5	Arabidopsis thaliana	24%	87%
Q8RXZ9	Arabidopsis thaliana	25%	95%
Q8SQH5	Bos taurus	52%	100%
Q8TFH2	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	100%
Q8WUT9	Homo sapiens	28%	93%
Q922G0	Mus musculus	26%	100%
Q93XM7	Arabidopsis thaliana	21%	100%
Q944H5	Arabidopsis thaliana	23%	77%
Q95J75	Macaca fascicularis	27%	100%
Q96CQ1	Homo sapiens	25%	100%
Q96H78	Homo sapiens	21%	100%
Q99297	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	100%
Q9BQT8	Homo sapiens	23%	100%
Q9BSK2	Homo sapiens	25%	99%
Q9BV35	Homo sapiens	27%	68%
Q9C9R4	Arabidopsis thaliana	25%	76%
Q9CA93	Arabidopsis thaliana	23%	100%
Q9CR58	Mus musculus	25%	100%
Q9CR62	Mus musculus	24%	100%
Q9D6M3	Mus musculus	23%	98%
Q9DAM5	Mus musculus	22%	100%
Q9DB41	Mus musculus	23%	99%
Q9ER18	Phodopus sungorus	24%	100%
Q9FI73	Arabidopsis thaliana	24%	94%
Q9FLS8	Arabidopsis thaliana	26%	66%
Q9FM86	Arabidopsis thaliana	35%	96%
Q9FY68	Arabidopsis thaliana	24%	94%
Q9GMZ1	Canis lupus familiaris	22%	100%
Q9H0C2	Homo sapiens	49%	100%
Q9H1K4	Homo sapiens	23%	100%
Q9H2D1	Homo sapiens	27%	100%
Q9H936	Homo sapiens	22%	98%
Q9HC21	Homo sapiens	22%	99%
Q9LJX5	Arabidopsis thaliana	25%	91%
Q9LV81	Arabidopsis thaliana	25%	74%
Q9LY28	Arabidopsis thaliana	27%	66%
Q9M024	Arabidopsis thaliana	28%	76%
Q9M038	Arabidopsis thaliana	23%	100%
Q9N2I9	Canis lupus familiaris	24%	100%
Q9N2J1	Canis lupus familiaris	24%	100%
Q9P3T7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	100%
Q9P6L7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	88%
Q9QZD8	Mus musculus	23%	100%
Q9SB52	Arabidopsis thaliana	21%	100%
Q9SJY5	Arabidopsis thaliana	21%	100%
Q9SUV1	Arabidopsis thaliana	26%	81%
Q9UTN1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	99%
Q9VM51	Drosophila melanogaster	26%	100%
Q9VMK1	Drosophila melanogaster	25%	95%
Q9VQ37	Drosophila melanogaster	24%	87%
Q9VQG4	Drosophila melanogaster	23%	100%
Q9W720	Danio rerio	23%	100%
Q9W725	Cyprinus carpio	23%	100%
Q9XI74	Arabidopsis thaliana	26%	100%
Q9Z2B2	Mus musculus	24%	98%
Q9Z2Z6	Mus musculus	26%	100%
Q9ZWG1	Arabidopsis thaliana	24%	100%
V5B150	Trypanosoma cruzi	22%	100%
V5BDR1	Trypanosoma cruzi	24%	100%
V5BKU8	Trypanosoma cruzi	24%	82%
V5BNE7	Trypanosoma cruzi	23%	99%
V5BTA6	Trypanosoma cruzi	22%	100%
V5BTC0	Trypanosoma cruzi	30%	97%
V5BWX9	Trypanosoma cruzi	79%	100%
V5DFB9	Trypanosoma cruzi	26%	100%
W5PSH7	Ovis aries	25%	100%