Chromosome partition protein Smc

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QDE9_LEIMA

TriTrypDb:

LmjF.19.0720 , LMJLV39_190012800 , LMJSD75_190012500

Length:

304

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QDE9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QDE9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	255	259	PF00656	0.524
CLV_C14_Caspase3-7	98	102	PF00656	0.384
CLV_NRD_NRD_1	291	293	PF00675	0.525
CLV_PCSK_SKI1_1	125	129	PF00082	0.463
CLV_PCSK_SKI1_1	178	182	PF00082	0.584
CLV_PCSK_SKI1_1	197	201	PF00082	0.481
CLV_PCSK_SKI1_1	247	251	PF00082	0.469
DEG_APCC_DBOX_1	196	204	PF00400	0.518
DEG_APCC_DBOX_1	246	254	PF00400	0.477
DEG_Nend_UBRbox_2	1	3	PF02207	0.526
DEG_SPOP_SBC_1	297	301	PF00917	0.619
DOC_USP7_MATH_1	252	256	PF00917	0.533
DOC_USP7_UBL2_3	153	157	PF12436	0.532
DOC_WW_Pin1_4	293	298	PF00397	0.672
LIG_14-3-3_CanoR_1	125	131	PF00244	0.526
LIG_BIR_III_4	101	105	PF00653	0.393
LIG_FHA_2	274	280	PF00498	0.531
LIG_LIR_Gen_1	272	283	PF02991	0.609
LIG_LIR_Nem_3	208	214	PF02991	0.466
LIG_LIR_Nem_3	266	271	PF02991	0.540
LIG_LIR_Nem_3	272	278	PF02991	0.590
LIG_NRP_CendR_1	303	304	PF00754	0.646
LIG_RPA_C_Fungi	222	234	PF08784	0.437
LIG_SH2_SRC	67	70	PF00017	0.390
LIG_SH2_STAT5	67	70	PF00017	0.383
LIG_TRAF2_1	213	216	PF00917	0.423
MOD_CK1_1	204	210	PF00069	0.507
MOD_CK1_1	296	302	PF00069	0.673
MOD_CK2_1	210	216	PF00069	0.426
MOD_CK2_1	273	279	PF00069	0.447
MOD_GlcNHglycan	190	193	PF01048	0.649
MOD_GlcNHglycan	215	219	PF01048	0.450
MOD_GlcNHglycan	238	242	PF01048	0.605
MOD_GSK3_1	126	133	PF00069	0.476
MOD_GSK3_1	210	217	PF00069	0.425
MOD_GSK3_1	293	300	PF00069	0.629
MOD_LATS_1	151	157	PF00433	0.398
MOD_NEK2_1	130	135	PF00069	0.482
MOD_NEK2_1	18	23	PF00069	0.464
MOD_NEK2_1	288	293	PF00069	0.586
MOD_NEK2_1	37	42	PF00069	0.452
MOD_NEK2_1	7	12	PF00069	0.482
MOD_NEK2_2	298	303	PF00069	0.582
MOD_PIKK_1	37	43	PF00454	0.464
MOD_PKA_2	130	136	PF00069	0.512
MOD_PKA_2	188	194	PF00069	0.687
MOD_Plk_1	237	243	PF00069	0.544
MOD_ProDKin_1	293	299	PF00069	0.674
MOD_SUMO_rev_2	97	105	PF00179	0.487
TRG_DiLeu_BaLyEn_6	9	14	PF01217	0.611
TRG_ER_diArg_1	302	304	PF00400	0.642
TRG_ER_diArg_1	81	84	PF00400	0.530
TRG_Pf-PMV_PEXEL_1	56	60	PF00026	0.491

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIA8	Leptomonas seymouri	76%	100%
A0A1X0P7A5	Trypanosomatidae	37%	97%
A0A3Q8IB89	Leishmania donovani	95%	100%
A0A422NN36	Trypanosoma rangeli	35%	100%
A4HA29	Leishmania braziliensis	83%	100%
A4HY92	Leishmania infantum	95%	100%
D0A0M5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	100%
E9AS24	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
V5B7K2	Trypanosoma cruzi	36%	99%