4-coumarate:coa ligase-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

4-coumarate:coa ligase-like protein

Species:

Leishmania major

UniProt:

Q4QDB5_LEIMA

TriTrypDb:

LmjF.19.1005 , LMJLV39_190015500 , LMJSD75_190015400

Length:

603

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 45

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 32

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 16
NetGPI	no	yes: 0, no: 16

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4QDB5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QDB5

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	17
GO:0016207	4-coumarate-CoA ligase activity	5	14
GO:0016405	CoA-ligase activity	4	14
GO:0016874	ligase activity	2	17
GO:0016877	ligase activity, forming carbon-sulfur bonds	3	14
GO:0016878	acid-thiol ligase activity	4	14

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	407	411	PF00656	0.322
CLV_NRD_NRD_1	100	102	PF00675	0.427
CLV_NRD_NRD_1	160	162	PF00675	0.383
CLV_NRD_NRD_1	176	178	PF00675	0.525
CLV_NRD_NRD_1	567	569	PF00675	0.551
CLV_NRD_NRD_1	570	572	PF00675	0.515
CLV_PCSK_KEX2_1	189	191	PF00082	0.450
CLV_PCSK_KEX2_1	328	330	PF00082	0.373
CLV_PCSK_KEX2_1	545	547	PF00082	0.455
CLV_PCSK_KEX2_1	567	569	PF00082	0.551
CLV_PCSK_KEX2_1	57	59	PF00082	0.505
CLV_PCSK_PC1ET2_1	189	191	PF00082	0.303
CLV_PCSK_PC1ET2_1	328	330	PF00082	0.432
CLV_PCSK_PC1ET2_1	545	547	PF00082	0.455
CLV_PCSK_PC1ET2_1	57	59	PF00082	0.505
CLV_PCSK_SKI1_1	152	156	PF00082	0.454
CLV_PCSK_SKI1_1	225	229	PF00082	0.451
CLV_PCSK_SKI1_1	391	395	PF00082	0.417
CLV_PCSK_SKI1_1	57	61	PF00082	0.416
CLV_PCSK_SKI1_1	591	595	PF00082	0.570
CLV_PCSK_SKI1_1	76	80	PF00082	0.397
CLV_Separin_Metazoa	556	560	PF03568	0.455
DEG_SPOP_SBC_1	10	14	PF00917	0.605
DOC_ANK_TNKS_1	373	380	PF00023	0.287
DOC_CYCLIN_yClb5_NLxxxL_5	559	565	PF00134	0.382
DOC_CYCLIN_yCln2_LP_2	129	135	PF00134	0.312
DOC_MAPK_gen_1	296	303	PF00069	0.457
DOC_MAPK_gen_1	545	553	PF00069	0.401
DOC_MAPK_gen_1	99	108	PF00069	0.422
DOC_MAPK_MEF2A_6	101	110	PF00069	0.420
DOC_MAPK_MEF2A_6	347	354	PF00069	0.335
DOC_MAPK_MEF2A_6	493	500	PF00069	0.518
DOC_PP1_RVXF_1	502	509	PF00149	0.455
DOC_PP2B_LxvP_1	303	306	PF13499	0.525
DOC_PP4_FxxP_1	508	511	PF00568	0.495
DOC_USP7_MATH_1	137	141	PF00917	0.399
DOC_USP7_MATH_1	215	219	PF00917	0.306
DOC_USP7_MATH_1	350	354	PF00917	0.335
DOC_USP7_MATH_1	513	517	PF00917	0.335
DOC_USP7_MATH_1	597	601	PF00917	0.604
DOC_USP7_UBL2_3	314	318	PF12436	0.436
DOC_USP7_UBL2_3	467	471	PF12436	0.401
DOC_USP7_UBL2_3	62	66	PF12436	0.303
DOC_WW_Pin1_4	12	17	PF00397	0.602
DOC_WW_Pin1_4	128	133	PF00397	0.518
DOC_WW_Pin1_4	245	250	PF00397	0.335
DOC_WW_Pin1_4	475	480	PF00397	0.563
DOC_WW_Pin1_4	519	524	PF00397	0.486
LIG_14-3-3_CanoR_1	44	52	PF00244	0.309
LIG_14-3-3_CanoR_1	512	518	PF00244	0.416
LIG_14-3-3_CanoR_1	528	536	PF00244	0.390
LIG_14-3-3_CanoR_1	552	561	PF00244	0.303
LIG_14-3-3_CanoR_1	8	16	PF00244	0.585
LIG_BIR_II_1	1	5	PF00653	0.541
LIG_BIR_III_2	410	414	PF00653	0.478
LIG_EH1_1	274	282	PF00400	0.335
LIG_FHA_1	2	8	PF00498	0.566
LIG_FHA_1	209	215	PF00498	0.399
LIG_FHA_1	218	224	PF00498	0.403
LIG_FHA_1	264	270	PF00498	0.486
LIG_FHA_1	298	304	PF00498	0.471
LIG_FHA_1	445	451	PF00498	0.430
LIG_FHA_1	461	467	PF00498	0.401
LIG_FHA_2	284	290	PF00498	0.335
LIG_FHA_2	48	54	PF00498	0.353
LIG_LIR_Apic_2	505	511	PF02991	0.455
LIG_LIR_Gen_1	50	59	PF02991	0.352
LIG_LIR_Gen_1	77	86	PF02991	0.335
LIG_LIR_Nem_3	113	119	PF02991	0.382
LIG_LIR_Nem_3	199	203	PF02991	0.461
LIG_LIR_Nem_3	36	41	PF02991	0.455
LIG_LIR_Nem_3	50	55	PF02991	0.458
LIG_LIR_Nem_3	531	537	PF02991	0.382
LIG_LIR_Nem_3	77	83	PF02991	0.456
LIG_LYPXL_yS_3	38	41	PF13949	0.335
LIG_MYND_2	306	310	PF01753	0.525
LIG_NRBOX	308	314	PF00104	0.423
LIG_NRBOX	481	487	PF00104	0.455
LIG_Pex14_2	187	191	PF04695	0.392
LIG_REV1ctd_RIR_1	185	194	PF16727	0.525
LIG_SH2_CRK	116	120	PF00017	0.457
LIG_SH2_CRK	121	125	PF00017	0.457
LIG_SH2_CRK	200	204	PF00017	0.450
LIG_SH2_CRK	534	538	PF00017	0.407
LIG_SH2_CRK	80	84	PF00017	0.396
LIG_SH2_PTP2	192	195	PF00017	0.335
LIG_SH2_SRC	273	276	PF00017	0.335
LIG_SH2_STAP1	52	56	PF00017	0.355
LIG_SH2_STAP1	80	84	PF00017	0.531
LIG_SH2_STAT5	144	147	PF00017	0.418
LIG_SH2_STAT5	159	162	PF00017	0.248
LIG_SH2_STAT5	192	195	PF00017	0.335
LIG_SH2_STAT5	285	288	PF00017	0.429
LIG_SH2_STAT5	290	293	PF00017	0.405
LIG_SH2_STAT5	430	433	PF00017	0.401
LIG_SH2_STAT5	54	57	PF00017	0.547
LIG_SH3_3	209	215	PF00018	0.279
LIG_SH3_3	301	307	PF00018	0.368
LIG_SH3_3	333	339	PF00018	0.335
LIG_SH3_3	364	370	PF00018	0.408
LIG_SH3_3	418	424	PF00018	0.454
LIG_SH3_3	497	503	PF00018	0.380
LIG_SUMO_SIM_anti_2	165	172	PF11976	0.448
LIG_SUMO_SIM_par_1	306	311	PF11976	0.457
LIG_TYR_ITIM	114	119	PF00017	0.475
LIG_TYR_ITIM	78	83	PF00017	0.493
LIG_UBA3_1	154	162	PF00899	0.335
LIG_UBA3_1	308	314	PF00899	0.457
LIG_UBA3_1	55	62	PF00899	0.370
MOD_CDK_SPK_2	519	524	PF00069	0.303
MOD_CK1_1	11	17	PF00069	0.602
MOD_CK1_1	217	223	PF00069	0.403
MOD_CK1_1	398	404	PF00069	0.450
MOD_CK1_1	478	484	PF00069	0.605
MOD_CK2_1	47	53	PF00069	0.360
MOD_CK2_1	589	595	PF00069	0.656
MOD_CMANNOS	191	194	PF00535	0.335
MOD_Cter_Amidation	175	178	PF01082	0.525
MOD_GlcNHglycan	217	220	PF01048	0.403
MOD_GlcNHglycan	400	403	PF01048	0.457
MOD_GlcNHglycan	406	409	PF01048	0.457
MOD_GlcNHglycan	561	564	PF01048	0.370
MOD_GlcNHglycan	585	588	PF01048	0.652
MOD_GlcNHglycan	591	594	PF01048	0.644
MOD_GlcNHglycan	599	602	PF01048	0.541
MOD_GSK3_1	16	23	PF00069	0.572
MOD_GSK3_1	204	211	PF00069	0.422
MOD_GSK3_1	217	224	PF00069	0.316
MOD_GSK3_1	319	326	PF00069	0.349
MOD_GSK3_1	33	40	PF00069	0.512
MOD_GSK3_1	348	355	PF00069	0.279
MOD_GSK3_1	400	407	PF00069	0.351
MOD_GSK3_1	513	520	PF00069	0.335
MOD_GSK3_1	585	592	PF00069	0.628
MOD_GSK3_1	8	15	PF00069	0.602
MOD_N-GLC_1	322	327	PF02516	0.239
MOD_N-GLC_1	559	564	PF02516	0.364
MOD_N-GLC_1	597	602	PF02516	0.594
MOD_NEK2_1	1	6	PF00069	0.703
MOD_NEK2_1	110	115	PF00069	0.444
MOD_NEK2_1	208	213	PF00069	0.461
MOD_NEK2_1	485	490	PF00069	0.455
MOD_NEK2_1	536	541	PF00069	0.328
MOD_NEK2_1	78	83	PF00069	0.408
MOD_NEK2_1	9	14	PF00069	0.773
MOD_PIKK_1	1	7	PF00454	0.641
MOD_PIKK_1	352	358	PF00454	0.525
MOD_PIKK_1	395	401	PF00454	0.457
MOD_PK_1	37	43	PF00069	0.594
MOD_PKA_2	527	533	PF00069	0.425
MOD_Plk_1	208	214	PF00069	0.403
MOD_Plk_1	322	328	PF00069	0.403
MOD_Plk_1	433	439	PF00069	0.455
MOD_Plk_1	47	53	PF00069	0.555
MOD_Plk_1	504	510	PF00069	0.455
MOD_Plk_1	76	82	PF00069	0.335
MOD_Plk_4	110	116	PF00069	0.525
MOD_Plk_4	137	143	PF00069	0.303
MOD_Plk_4	208	214	PF00069	0.318
MOD_Plk_4	37	43	PF00069	0.602
MOD_Plk_4	433	439	PF00069	0.364
MOD_ProDKin_1	12	18	PF00069	0.601
MOD_ProDKin_1	128	134	PF00069	0.518
MOD_ProDKin_1	245	251	PF00069	0.335
MOD_ProDKin_1	475	481	PF00069	0.565
MOD_ProDKin_1	519	525	PF00069	0.486
TRG_DiLeu_BaEn_1	456	461	PF01217	0.518
TRG_DiLeu_BaEn_2	531	537	PF01217	0.439
TRG_DiLeu_BaEn_3	165	171	PF01217	0.335
TRG_ENDOCYTIC_2	116	119	PF00928	0.457
TRG_ENDOCYTIC_2	121	124	PF00928	0.457
TRG_ENDOCYTIC_2	200	203	PF00928	0.457
TRG_ENDOCYTIC_2	38	41	PF00928	0.411
TRG_ENDOCYTIC_2	472	475	PF00928	0.613
TRG_ENDOCYTIC_2	52	55	PF00928	0.508
TRG_ENDOCYTIC_2	534	537	PF00928	0.364
TRG_ENDOCYTIC_2	80	83	PF00928	0.457
TRG_ER_diArg_1	566	568	PF00400	0.550
TRG_Pf-PMV_PEXEL_1	162	166	PF00026	0.450
TRG_Pf-PMV_PEXEL_1	49	53	PF00026	0.350

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0H2ZF83	Pseudomonas aeruginosa (strain UCBPP-PA14)	26%	100%
A0A0N1IFY3	Leptomonas seymouri	65%	100%
A0A0S4IL67	Bodo saltans	21%	78%
A0A0S4J3H6	Bodo saltans	41%	100%
A0A0S4KJT4	Bodo saltans	25%	87%
A0A1X0NYC1	Trypanosomatidae	23%	89%
A0A1X0NYG3	Trypanosomatidae	23%	89%
A0A1X0NYK4	Trypanosomatidae	22%	83%
A0A2H5AIX5	Narcissus pseudonarcissus	32%	100%
A0A2H5AIY4	Narcissus pseudonarcissus	29%	100%
A0A3G1DJF8	Phoma sp. (strain ATCC 20986 / MF5453)	24%	100%
A0A3Q8ID29	Leishmania donovani	21%	81%
A0A3R7JTL0	Trypanosoma rangeli	23%	89%
A0A3S7WVG2	Leishmania donovani	69%	99%
A0A3S7WVH9	Leishmania donovani	96%	100%
A0A3S7WVL1	Leishmania donovani	70%	100%
A0A422NFF5	Trypanosoma rangeli	24%	86%
A0A451EJM7	Leishmania donovani	24%	86%
A0KNI2	Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)	23%	93%
A0L576	Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1)	24%	94%
A0LG91	Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)	24%	93%
A0R4Q2	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	24%	100%
A0RK73	Bacillus thuringiensis (strain Al Hakam)	27%	100%
A1A787	Escherichia coli O1:K1 / APEC	25%	100%
A1AF47	Escherichia coli O1:K1 / APEC	25%	84%
A1JIK3	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	23%	92%
A1JPF0	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	26%	84%
A1SZA2	Psychromonas ingrahamii (strain 37)	23%	93%
A1WY97	Halorhodospira halophila (strain DSM 244 / SL1)	23%	93%
A2QTE5	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	30%	100%
A4G3L8	Herminiimonas arsenicoxydans	24%	91%
A4HA52	Leishmania braziliensis	85%	100%
A4HGG0	Leishmania braziliensis	22%	81%
A4HRT4	Leishmania infantum	24%	86%
A4HYA8	Leishmania infantum	69%	100%
A4HYB7	Leishmania infantum	96%	100%
A4I3J3	Leishmania infantum	21%	82%
A4SJM6	Aeromonas salmonicida (strain A449)	23%	93%
A4TLD3	Yersinia pestis (strain Pestoides F)	24%	84%
A4TS06	Yersinia pestis (strain Pestoides F)	23%	92%
A4WE11	Enterobacter sp. (strain 638)	26%	84%
A4YDR9	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	25%	100%
A4YK73	Bradyrhizobium sp. (strain ORS 278)	24%	93%
A6TDH2	Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)	26%	84%
A7FFD1	Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)	24%	84%
A7FNG1	Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)	23%	92%
A7GU88	Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)	27%	100%
A7IFD4	Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)	23%	93%
A7MPJ7	Cronobacter sakazakii (strain ATCC BAA-894)	22%	92%
A7MR36	Cronobacter sakazakii (strain ATCC BAA-894)	26%	84%
A7Z809	Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42)	29%	100%
A7ZHC8	Escherichia coli O139:H28 (strain E24377A / ETEC)	25%	100%
A7ZQU2	Escherichia coli O139:H28 (strain E24377A / ETEC)	25%	84%
A7ZVY7	Escherichia coli O9:H4 (strain HS)	25%	100%
A8A3X0	Escherichia coli O9:H4 (strain HS)	25%	84%
A8ALR6	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	23%	100%
A8AN29	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	23%	92%
A8AP56	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	26%	84%
A8G8G7	Serratia proteamaculans (strain 568)	22%	92%
A8PDE3	Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)	25%	91%
A9MQH7	Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)	24%	100%
A9MYJ6	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	22%	100%
A9N3H8	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	26%	84%
A9R2S1	Yersinia pestis bv. Antiqua (strain Angola)	24%	84%
A9VM74	Bacillus mycoides (strain KBAB4)	27%	100%
B0S8X7	Leptospira biflexa serovar Patoc (strain Patoc 1 / Ames)	23%	92%
B0SRX5	Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris)	23%	92%
B1IRD9	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	25%	100%
B1IU08	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	25%	84%
B1JQC1	Yersinia pseudotuberculosis serotype O:3 (strain YPIII)	24%	84%
B1LFX0	Escherichia coli (strain SMS-3-5 / SECEC)	25%	100%
B1LR34	Escherichia coli (strain SMS-3-5 / SECEC)	25%	84%
B1M0M1	Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1)	24%	93%
B1XBG2	Escherichia coli (strain K12 / DH10B)	24%	100%
B1XDP2	Escherichia coli (strain K12 / DH10B)	25%	84%
B1ZB59	Methylorubrum populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001)	23%	93%
B2HI05	Mycobacterium marinum (strain ATCC BAA-535 / M)	24%	100%
B2JD61	Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815)	23%	91%
B2JZ75	Yersinia pseudotuberculosis serotype IB (strain PB1/+)	24%	84%
B2KWI3	Ajellomyces capsulatus	24%	100%
B2TYQ5	Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)	25%	84%
B2VFS7	Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)	26%	84%
B4EY25	Proteus mirabilis (strain HI4320)	26%	100%
B4T503	Salmonella newport (strain SL254)	26%	84%
B4T6J6	Salmonella newport (strain SL254)	22%	100%
B4TGR5	Salmonella heidelberg (strain SL476)	26%	84%
B4TIH0	Salmonella heidelberg (strain SL476)	22%	100%
B4TUM9	Salmonella schwarzengrund (strain CVM19633)	25%	84%
B4TWR4	Salmonella schwarzengrund (strain CVM19633)	22%	100%
B5BFH6	Salmonella paratyphi A (strain AKU_12601)	25%	84%
B5BL55	Salmonella paratyphi A (strain AKU_12601)	23%	100%
B5F4V4	Salmonella agona (strain SL483)	26%	84%
B5F750	Salmonella agona (strain SL483)	21%	100%
B5FHG5	Salmonella dublin (strain CT_02021853)	22%	100%
B5FUB9	Salmonella dublin (strain CT_02021853)	25%	84%
B5QWU2	Salmonella enteritidis PT4 (strain P125109)	26%	84%
B5R1R0	Salmonella enteritidis PT4 (strain P125109)	21%	100%
B5RDY6	Salmonella gallinarum (strain 287/91 / NCTC 13346)	26%	84%
B5XUP2	Klebsiella pneumoniae (strain 342)	26%	84%
B5YYD1	Escherichia coli O157:H7 (strain EC4115 / EHEC)	25%	100%
B5Z4F4	Escherichia coli O157:H7 (strain EC4115 / EHEC)	25%	84%
B5Z6E9	Helicobacter pylori (strain G27)	23%	91%
B6HYY8	Escherichia coli (strain SE11)	25%	100%
B6I6W1	Escherichia coli (strain SE11)	25%	84%
B7HTW3	Bacillus cereus (strain AH187)	27%	100%
B7JDD6	Bacillus cereus (strain AH820)	28%	100%
B7L4G0	Escherichia coli (strain 55989 / EAEC)	25%	100%
B7LF13	Escherichia coli (strain 55989 / EAEC)	25%	84%
B7LNJ2	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	25%	84%
B7LWM8	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	25%	100%
B7M0D4	Escherichia coli O8 (strain IAI1)	25%	100%
B7MAG0	Escherichia coli O45:K1 (strain S88 / ExPEC)	25%	100%
B7MLI2	Escherichia coli O45:K1 (strain S88 / ExPEC)	25%	84%
B7MNP4	Escherichia coli O81 (strain ED1a)	24%	100%
B7N768	Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)	25%	84%
B7N7R2	Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)	25%	100%
B7NHE1	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	25%	100%
B7NVY2	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	25%	84%
B7UHQ4	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	25%	84%
B7UI83	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	25%	100%
B8FIN2	Desulfatibacillum aliphaticivorans	23%	93%
B9J2F2	Bacillus cereus (strain Q1)	27%	100%
C0PXJ8	Salmonella paratyphi C (strain RKS4594)	26%	84%
C0Q4L3	Salmonella paratyphi C (strain RKS4594)	22%	100%
C0SPB0	Bacillus subtilis (strain 168)	24%	100%
C1D6V9	Laribacter hongkongensis (strain HLHK9)	25%	92%
C3LB87	Bacillus anthracis (strain CDC 684 / NRRL 3495)	27%	100%
C3PCK3	Bacillus anthracis (strain A0248)	27%	100%
C4ZPW3	Escherichia coli (strain K12 / MC4100 / BW2952)	24%	100%
C4ZZY9	Escherichia coli (strain K12 / MC4100 / BW2952)	25%	84%
C5D6U5	Geobacillus sp. (strain WCH70)	27%	100%
C5NN18	Alternaria alternata	28%	100%
C6DE43	Pectobacterium carotovorum subsp. carotovorum (strain PC1)	25%	83%
C9ZXK3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	86%
D0A7V2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	83%
E9AGS5	Leishmania infantum	69%	83%
E9AGS6	Leishmania infantum	70%	100%
E9AS49	Leishmania mexicana (strain MHOM/GT/2001/U1103)	69%	93%
E9AS50	Leishmania mexicana (strain MHOM/GT/2001/U1103)	66%	95%
E9AS51	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	91%
E9AW57	Leishmania mexicana (strain MHOM/GT/2001/U1103)	21%	85%
E9AW86	Leishmania mexicana (strain MHOM/GT/2001/U1103)	21%	87%
E9AZT3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	21%	81%
F4HUK6	Arabidopsis thaliana	25%	100%
G3XMC0	Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a / NRRL 328 / USDA 3528.7)	30%	100%
I3PB37	Petunia hybrida	31%	100%
K0E2F3	Aspergillus rugulosus	26%	100%
M4IQQ5	Humulus lupulus	25%	100%
M4IQQ7	Humulus lupulus	27%	100%
M4IQR7	Humulus lupulus	33%	100%
M4IQS1	Humulus lupulus	31%	100%
M4IRL4	Humulus lupulus	23%	100%
M4IRL6	Humulus lupulus	32%	100%
M4IS88	Humulus lupulus	23%	100%
M4IS92	Humulus lupulus	24%	100%
M4ISH0	Humulus lupulus	29%	100%
O07610	Bacillus subtilis (strain 168)	26%	100%
O07899	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	23%	100%
O13440	Coprinopsis cinerea	25%	91%
O24145	Nicotiana tabacum	30%	100%
O24146	Nicotiana tabacum	30%	100%
O24540	Vanilla planifolia	30%	100%
O31826	Bacillus subtilis (strain 168)	25%	100%
O54154	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	23%	100%
O60011	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	23%	85%
O68040	Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)	22%	92%
O70490	Rattus norvegicus	22%	100%
O80658	Arabidopsis thaliana	26%	100%
O93730	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	24%	90%
O93800	Alternaria alternata	28%	100%
O94049	Candida albicans	24%	89%
P08659	Photinus pyralis	31%	100%
P0C5B6	Arabidopsis thaliana	31%	100%
P13129	Luciola cruciata	31%	100%
P14912	Petroselinum crispum	31%	100%
P14913	Petroselinum crispum	31%	100%
P16928	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	24%	90%
P16929	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	24%	90%
P17814	Oryza sativa subsp. japonica	29%	100%
P23971	Bacillus subtilis (strain 168)	27%	100%
P27550	Escherichia coli (strain K12)	23%	92%
P28812	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	24%	96%
P31119	Escherichia coli (strain K12)	25%	84%
P31552	Escherichia coli (strain K12)	24%	100%
P31684	Solanum tuberosum	29%	100%
P31685	Solanum tuberosum	29%	100%
P31687	Glycine max	29%	100%
P36333	Penicillium chrysogenum	24%	90%
P38137	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	100%
P39062	Bacillus subtilis (strain 168)	21%	100%
P40871	Bacillus subtilis (strain 168)	24%	100%
P41636	Pinus taeda	29%	100%
P46450	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	27%	100%
P58730	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)	24%	100%
P63521	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	27%	100%
P63522	Salmonella typhi	27%	100%
P69451	Escherichia coli (strain K12)	28%	100%
P69452	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	28%	100%
P78773	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	91%
P86831	Arthrobacter sp.	24%	100%
P86832	Arthrobacter sp.	24%	100%
P94547	Bacillus subtilis (strain 168)	29%	100%
P96575	Bacillus subtilis (strain 168)	26%	100%
P9WQ36	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	25%	100%
P9WQ37	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	25%	100%
P9WQ50	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	25%	100%
P9WQ51	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	25%	100%
Q01158	Aquatica lateralis	30%	100%
Q01574	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	85%
Q01576	Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC 33097 / NRRL 1555)	22%	90%
Q04P35	Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)	23%	92%
Q056J9	Leptospira borgpetersenii serovar Hardjo-bovis (strain L550)	23%	92%
Q07VK4	Rhodopseudomonas palustris (strain BisA53)	24%	93%
Q08AH1	Homo sapiens	22%	100%
Q08AH3	Homo sapiens	22%	100%
Q0AAW0	Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1)	23%	93%
Q0DV32	Oryza sativa subsp. japonica	31%	100%
Q0K844	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	26%	100%
Q0S4D9	Rhodococcus jostii (strain RHA1)	28%	100%
Q0T128	Shigella flexneri serotype 5b (strain 8401)	25%	84%
Q0T8F7	Shigella flexneri serotype 5b (strain 8401)	24%	100%
Q0TDZ6	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	25%	84%
Q0TLV2	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	25%	100%
Q10S72	Oryza sativa subsp. japonica	31%	100%
Q17577	Caenorhabditis elegans	31%	100%
Q1C0N0	Yersinia pestis bv. Antiqua (strain Antiqua)	23%	92%
Q1CAS8	Yersinia pestis bv. Antiqua (strain Antiqua)	24%	84%
Q1CE37	Yersinia pestis bv. Antiqua (strain Nepal516)	23%	92%
Q1H0J2	Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875)	23%	92%
Q1R7H5	Escherichia coli (strain UTI89 / UPEC)	25%	84%
Q1RGG1	Escherichia coli (strain UTI89 / UPEC)	25%	100%
Q21LV0	Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)	24%	93%
Q26304	Luciola mingrelica	29%	100%
Q27757	Photuris pensylvanica	27%	100%
Q2G512	Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199)	25%	93%
Q2NR28	Sodalis glossinidius (strain morsitans)	23%	92%
Q2NXE2	Xanthomonas oryzae pv. oryzae (strain MAFF 311018)	23%	93%
Q2UB01	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	27%	100%
Q32K60	Shigella dysenteriae serotype 1 (strain Sd197)	25%	100%
Q3E6Y4	Arabidopsis thaliana	32%	100%
Q3YY21	Shigella sonnei (strain Ss046)	25%	84%
Q3Z5X2	Shigella sonnei (strain Ss046)	25%	100%
Q42524	Arabidopsis thaliana	32%	100%
Q42982	Oryza sativa subsp. japonica	31%	100%
Q4G176	Homo sapiens	25%	100%
Q4KCY5	Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)	23%	100%
Q4Q8F1	Leishmania major	22%	81%
Q4QBC0	Leishmania major	21%	100%
Q4QDB6	Leishmania major	71%	100%
Q4QDB7	Leishmania major	72%	98%
Q4UP35	Xanthomonas campestris pv. campestris (strain 8004)	22%	93%
Q4WR83	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	26%	100%
Q4ZQG8	Pseudomonas syringae pv. syringae (strain B728a)	23%	93%
Q53005	Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)	24%	100%
Q54P77	Dictyostelium discoideum	30%	100%
Q54P78	Dictyostelium discoideum	30%	100%
Q54P79	Dictyostelium discoideum	30%	100%
Q554Z5	Dictyostelium discoideum	25%	88%
Q55DR6	Dictyostelium discoideum	25%	90%
Q57KA7	Salmonella choleraesuis (strain SC-B67)	26%	84%
Q57TJ0	Salmonella choleraesuis (strain SC-B67)	22%	100%
Q5B7J0	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	26%	100%
Q5KVX9	Geobacillus kaustophilus (strain HTA426)	28%	100%
Q5LRT0	Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)	26%	100%
Q5PEN7	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	25%	84%
Q5PIL0	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	23%	100%
Q5SKN9	Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)	27%	100%
Q632I5	Bacillus cereus (strain ZK / E33L)	28%	100%
Q65FT5	Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)	28%	100%
Q667F1	Yersinia pseudotuberculosis serotype I (strain IP32953)	24%	84%
Q66FM8	Yersinia pseudotuberculosis serotype I (strain IP32953)	23%	92%
Q67W82	Oryza sativa subsp. japonica	31%	100%
Q68CK6	Homo sapiens	22%	100%
Q69RG7	Oryza sativa subsp. japonica	28%	100%
Q6BQF2	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	24%	90%
Q6BS00	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	25%	89%
Q6D107	Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)	24%	82%
Q6ETN3	Oryza sativa subsp. japonica	33%	100%
Q6FLU2	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	22%	86%
Q6FXI2	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	24%	88%
Q6GLK6	Xenopus laevis	25%	100%
Q6HC29	Bacillus thuringiensis subsp. konkukian (strain 97-27)	27%	100%
Q6MNF1	Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100)	23%	93%
Q6YYZ2	Oryza sativa subsp. japonica	30%	100%
Q6ZAC1	Oryza sativa subsp. japonica	31%	100%
Q71YZ5	Listeria monocytogenes serotype 4b (strain F2365)	23%	100%
Q72LY9	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)	23%	91%
Q74RZ6	Yersinia pestis	24%	84%
Q7F1X5	Oryza sativa subsp. japonica	29%	100%
Q7MBA6	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	23%	93%
Q7MGU3	Vibrio vulnificus (strain YJ016)	24%	93%
Q7N7A9	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	25%	94%
Q7NSY7	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	23%	92%
Q7TWB7	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	25%	100%
Q7WSH3	Comamonas testosteroni	28%	100%
Q7XXL2	Oryza sativa subsp. japonica	32%	100%
Q816I1	Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)	28%	100%
Q81K97	Bacillus anthracis	27%	100%
Q83JV7	Shigella flexneri	25%	84%
Q83MG9	Shigella flexneri	24%	100%
Q84HC5	Streptomyces carzinostaticus	24%	100%
Q84P21	Arabidopsis thaliana	34%	100%
Q84P23	Arabidopsis thaliana	30%	100%
Q84P24	Arabidopsis thaliana	31%	100%
Q84P25	Arabidopsis thaliana	30%	100%
Q84P26	Arabidopsis thaliana	32%	100%
Q87C00	Xylella fastidiosa (strain Temecula1 / ATCC 700964)	23%	93%
Q87KU7	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	23%	93%
Q885K7	Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)	23%	93%
Q89WV5	Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)	24%	93%
Q8D1G8	Yersinia pestis	23%	92%
Q8DCZ9	Vibrio vulnificus (strain CMCP6)	24%	93%
Q8ENZ7	Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)	25%	100%
Q8EYG2	Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)	23%	91%
Q8FAY8	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	23%	92%
Q8FEA6	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	25%	84%
Q8FLA5	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	25%	100%
Q8GB18	Proteus sp. (strain LE138)	25%	100%
Q8GQN9	Thauera aromatica	23%	100%
Q8GVF9	Oryza sativa subsp. japonica	27%	99%
Q8K0L3	Mus musculus	23%	100%
Q8NJN3	Candida albicans (strain SC5314 / ATCC MYA-2876)	26%	90%
Q8P3L1	Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)	22%	93%
Q8PF09	Xanthomonas axonopodis pv. citri (strain 306)	23%	93%
Q8RU95	Oryza sativa subsp. japonica	29%	100%
Q8VYJ1	Arabidopsis thaliana	26%	100%
Q8VZF1	Arabidopsis thaliana	23%	100%
Q8X6J8	Escherichia coli O157:H7	25%	84%
Q8XA34	Escherichia coli O157:H7	25%	100%
Q8XDR6	Escherichia coli O157:H7	28%	100%
Q8XY11	Ralstonia solanacearum (strain GMI1000)	23%	91%
Q8Z1R0	Salmonella typhi	22%	92%
Q8Z406	Salmonella typhi	26%	84%
Q8Z9L4	Salmonella typhi	22%	100%
Q8ZES9	Yersinia pestis	29%	100%
Q8ZKF6	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	22%	92%
Q8ZMA4	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	26%	84%
Q8ZRX4	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	22%	100%
Q91VA0	Mus musculus	23%	100%
Q92AY8	Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)	25%	100%
Q96VB5	Alternaria alternata	28%	100%
Q96VC7	Zygosaccharomyces bailii	24%	89%
Q973W5	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	25%	92%
Q98ET8	Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)	23%	93%
Q99NB1	Mus musculus	24%	88%
Q9AJS8	Thauera aromatica	22%	100%
Q9BEA2	Bos taurus	25%	100%
Q9C8D4	Arabidopsis thaliana	23%	100%
Q9C9G2	Arabidopsis thaliana	21%	100%
Q9EY88	Amycolatopsis sp.	27%	100%
Q9F7R5	Gamma-proteobacterium EBAC31A08	23%	94%
Q9FFE9	Arabidopsis thaliana	25%	100%
Q9HV66	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	23%	93%
Q9HWG3	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	26%	100%
Q9I558	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	23%	93%
Q9KV59	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	24%	93%
Q9LQ12	Arabidopsis thaliana	31%	100%
Q9LU36	Arabidopsis thaliana	29%	100%
Q9M0X9	Arabidopsis thaliana	32%	100%
Q9NUB1	Homo sapiens	23%	88%
Q9PB89	Xylella fastidiosa (strain 9a5c)	24%	93%
Q9S725	Arabidopsis thaliana	31%	100%
Q9S777	Arabidopsis thaliana	30%	100%
Q9SEY5	Arabidopsis thaliana	22%	100%
Q9SFW5	Arabidopsis thaliana	24%	100%
Q9SMT7	Arabidopsis thaliana	25%	100%
Q9SS00	Arabidopsis thaliana	22%	100%
Q9SS01	Arabidopsis thaliana	23%	100%
Q9U0W1	Leishmania major	22%	100%
Q9VP61	Drosophila melanogaster	24%	90%
Q9Y7B5	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	23%	88%
S3DB78	Glarea lozoyensis (strain ATCC 20868 / MF5171)	27%	100%
S5M744	Streptomyces sp.	27%	100%
V5ASG2	Trypanosoma cruzi	22%	89%
W7NDP3	Gibberella moniliformis (strain M3125 / FGSC 7600)	24%	100%