Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QD98_LEIMA

TriTrypDb:

LmjF.19.1170 , LMJLV39_190017300 , LMJSD75_190017300

Length:

928

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QD98

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QD98

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	123	127	PF00656	0.663
CLV_C14_Caspase3-7	401	405	PF00656	0.443
CLV_C14_Caspase3-7	562	566	PF00656	0.638
CLV_C14_Caspase3-7	576	580	PF00656	0.777
CLV_C14_Caspase3-7	911	915	PF00656	0.585
CLV_NRD_NRD_1	158	160	PF00675	0.724
CLV_NRD_NRD_1	20	22	PF00675	0.584
CLV_NRD_NRD_1	45	47	PF00675	0.646
CLV_NRD_NRD_1	464	466	PF00675	0.513
CLV_NRD_NRD_1	610	612	PF00675	0.815
CLV_PCSK_KEX2_1	158	160	PF00082	0.724
CLV_PCSK_KEX2_1	20	22	PF00082	0.584
CLV_PCSK_KEX2_1	464	466	PF00082	0.499
CLV_PCSK_KEX2_1	619	621	PF00082	0.744
CLV_PCSK_KEX2_1	96	98	PF00082	0.616
CLV_PCSK_PC1ET2_1	619	621	PF00082	0.680
CLV_PCSK_PC1ET2_1	96	98	PF00082	0.659
CLV_PCSK_PC7_1	460	466	PF00082	0.449
CLV_PCSK_SKI1_1	130	134	PF00082	0.625
CLV_PCSK_SKI1_1	143	147	PF00082	0.649
CLV_PCSK_SKI1_1	279	283	PF00082	0.702
CLV_PCSK_SKI1_1	403	407	PF00082	0.491
CLV_PCSK_SKI1_1	409	413	PF00082	0.489
CLV_PCSK_SKI1_1	415	419	PF00082	0.511
CLV_PCSK_SKI1_1	468	472	PF00082	0.458
CLV_PCSK_SKI1_1	578	582	PF00082	0.651
DEG_Nend_UBRbox_3	1	3	PF02207	0.611
DEG_SPOP_SBC_1	167	171	PF00917	0.685
DEG_SPOP_SBC_1	176	180	PF00917	0.656
DEG_SPOP_SBC_1	183	187	PF00917	0.576
DEG_SPOP_SBC_1	281	285	PF00917	0.638
DEG_SPOP_SBC_1	298	302	PF00917	0.536
DEG_SPOP_SBC_1	381	385	PF00917	0.665
DEG_SPOP_SBC_1	580	584	PF00917	0.662
DEG_SPOP_SBC_1	588	592	PF00917	0.594
DEG_SPOP_SBC_1	908	912	PF00917	0.709
DOC_CKS1_1	218	223	PF01111	0.670
DOC_CYCLIN_RxL_1	409	422	PF00134	0.548
DOC_CYCLIN_yCln2_LP_2	218	224	PF00134	0.709
DOC_CYCLIN_yCln2_LP_2	327	333	PF00134	0.635
DOC_MAPK_gen_1	20	26	PF00069	0.635
DOC_MAPK_RevD_3	8	21	PF00069	0.539
DOC_PP1_RVXF_1	128	134	PF00149	0.621
DOC_PP1_RVXF_1	880	886	PF00149	0.512
DOC_PP1_RVXF_1	94	101	PF00149	0.614
DOC_PP4_FxxP_1	635	638	PF00568	0.583
DOC_USP7_MATH_1	111	115	PF00917	0.584
DOC_USP7_MATH_1	139	143	PF00917	0.836
DOC_USP7_MATH_1	167	171	PF00917	0.674
DOC_USP7_MATH_1	183	187	PF00917	0.580
DOC_USP7_MATH_1	229	233	PF00917	0.671
DOC_USP7_MATH_1	234	238	PF00917	0.678
DOC_USP7_MATH_1	268	272	PF00917	0.740
DOC_USP7_MATH_1	281	285	PF00917	0.620
DOC_USP7_MATH_1	298	302	PF00917	0.678
DOC_USP7_MATH_1	316	320	PF00917	0.674
DOC_USP7_MATH_1	323	327	PF00917	0.606
DOC_USP7_MATH_1	34	38	PF00917	0.650
DOC_USP7_MATH_1	346	350	PF00917	0.619
DOC_USP7_MATH_1	365	369	PF00917	0.741
DOC_USP7_MATH_1	374	378	PF00917	0.744
DOC_USP7_MATH_1	381	385	PF00917	0.639
DOC_USP7_MATH_1	455	459	PF00917	0.527
DOC_USP7_MATH_1	484	488	PF00917	0.453
DOC_USP7_MATH_1	524	528	PF00917	0.788
DOC_USP7_MATH_1	568	572	PF00917	0.644
DOC_USP7_MATH_1	573	577	PF00917	0.638
DOC_USP7_MATH_1	580	584	PF00917	0.656
DOC_USP7_MATH_1	639	643	PF00917	0.625
DOC_USP7_MATH_1	694	698	PF00917	0.665
DOC_USP7_MATH_1	699	703	PF00917	0.605
DOC_USP7_MATH_1	705	709	PF00917	0.493
DOC_USP7_MATH_1	725	729	PF00917	0.610
DOC_USP7_MATH_1	908	912	PF00917	0.675
DOC_USP7_MATH_2	750	756	PF00917	0.666
DOC_USP7_UBL2_3	619	623	PF12436	0.679
DOC_WW_Pin1_4	177	182	PF00397	0.730
DOC_WW_Pin1_4	190	195	PF00397	0.564
DOC_WW_Pin1_4	2	7	PF00397	0.613
DOC_WW_Pin1_4	217	222	PF00397	0.663
DOC_WW_Pin1_4	237	242	PF00397	0.762
DOC_WW_Pin1_4	282	287	PF00397	0.665
DOC_WW_Pin1_4	288	293	PF00397	0.647
DOC_WW_Pin1_4	308	313	PF00397	0.606
DOC_WW_Pin1_4	339	344	PF00397	0.631
DOC_WW_Pin1_4	369	374	PF00397	0.767
DOC_WW_Pin1_4	37	42	PF00397	0.670
DOC_WW_Pin1_4	431	436	PF00397	0.677
DOC_WW_Pin1_4	437	442	PF00397	0.571
DOC_WW_Pin1_4	519	524	PF00397	0.709
DOC_WW_Pin1_4	679	684	PF00397	0.661
DOC_WW_Pin1_4	742	747	PF00397	0.655
DOC_WW_Pin1_4	753	758	PF00397	0.706
DOC_WW_Pin1_4	836	841	PF00397	0.621
DOC_WW_Pin1_4	897	902	PF00397	0.666
DOC_WW_Pin1_4	909	914	PF00397	0.796
LIG_14-3-3_CanoR_1	113	121	PF00244	0.643
LIG_14-3-3_CanoR_1	136	144	PF00244	0.660
LIG_14-3-3_CanoR_1	158	164	PF00244	0.738
LIG_14-3-3_CanoR_1	168	176	PF00244	0.680
LIG_14-3-3_CanoR_1	279	286	PF00244	0.623
LIG_14-3-3_CanoR_1	359	363	PF00244	0.673
LIG_14-3-3_CanoR_1	431	435	PF00244	0.588
LIG_14-3-3_CanoR_1	468	477	PF00244	0.507
LIG_14-3-3_CanoR_1	485	492	PF00244	0.537
LIG_14-3-3_CanoR_1	620	629	PF00244	0.735
LIG_14-3-3_CanoR_1	79	87	PF00244	0.568
LIG_14-3-3_CanoR_1	831	836	PF00244	0.638
LIG_14-3-3_CanoR_1	882	886	PF00244	0.515
LIG_14-3-3_CanoR_1	91	100	PF00244	0.621
LIG_Actin_WH2_2	388	405	PF00022	0.506
LIG_Actin_WH2_2	54	71	PF00022	0.459
LIG_APCC_ABBA_1	838	843	PF00400	0.646
LIG_CtBP_PxDLS_1	903	907	PF00389	0.601
LIG_FHA_1	185	191	PF00498	0.638
LIG_FHA_1	262	268	PF00498	0.653
LIG_FHA_1	289	295	PF00498	0.684
LIG_FHA_1	301	307	PF00498	0.628
LIG_FHA_1	395	401	PF00498	0.487
LIG_FHA_1	469	475	PF00498	0.614
LIG_FHA_1	49	55	PF00498	0.536
LIG_FHA_2	121	127	PF00498	0.666
LIG_FHA_2	186	192	PF00498	0.582
LIG_FXI_DFP_1	670	674	PF00024	0.533
LIG_LIR_Apic_2	796	802	PF02991	0.788
LIG_LIR_LC3C_4	487	492	PF02991	0.535
LIG_MYND_1	662	666	PF01753	0.738
LIG_MYND_1	836	840	PF01753	0.516
LIG_MYND_1	904	908	PF01753	0.601
LIG_Pex14_1	548	552	PF04695	0.492
LIG_PTAP_UEV_1	695	700	PF05743	0.637
LIG_SH2_CRK	677	681	PF00017	0.689
LIG_SH2_STAP1	50	54	PF00017	0.533
LIG_SH2_STAP1	552	556	PF00017	0.529
LIG_SH2_STAT3	853	856	PF00017	0.477
LIG_SH2_STAT3	858	861	PF00017	0.461
LIG_SH2_STAT5	50	53	PF00017	0.565
LIG_SH2_STAT5	841	844	PF00017	0.551
LIG_SH2_STAT5	858	861	PF00017	0.461
LIG_SH3_3	289	295	PF00018	0.781
LIG_SH3_3	30	36	PF00018	0.628
LIG_SH3_3	327	333	PF00018	0.727
LIG_SH3_3	449	455	PF00018	0.656
LIG_SH3_3	635	641	PF00018	0.693
LIG_SH3_3	656	662	PF00018	0.634
LIG_SH3_3	685	691	PF00018	0.736
LIG_SH3_3	693	699	PF00018	0.631
LIG_SH3_3	743	749	PF00018	0.774
LIG_SH3_3	754	760	PF00018	0.634
LIG_SH3_3	898	904	PF00018	0.696
LIG_SH3_3	910	916	PF00018	0.572
LIG_SUMO_SIM_anti_2	103	109	PF11976	0.657
LIG_SUMO_SIM_par_1	103	109	PF11976	0.657
LIG_SUMO_SIM_par_1	396	404	PF11976	0.493
LIG_SUMO_SIM_par_1	416	422	PF11976	0.481
LIG_SxIP_EBH_1	200	213	PF03271	0.555
LIG_TRAF2_2	760	765	PF00917	0.583
LIG_WW_3	440	444	PF00397	0.687
MOD_CDC14_SPxK_1	434	437	PF00782	0.686
MOD_CDK_SPxK_1	431	437	PF00069	0.678
MOD_CK1_1	109	115	PF00069	0.607
MOD_CK1_1	116	122	PF00069	0.673
MOD_CK1_1	170	176	PF00069	0.666
MOD_CK1_1	186	192	PF00069	0.562
MOD_CK1_1	237	243	PF00069	0.615
MOD_CK1_1	271	277	PF00069	0.786
MOD_CK1_1	37	43	PF00069	0.693
MOD_CK1_1	377	383	PF00069	0.587
MOD_CK1_1	527	533	PF00069	0.704
MOD_CK1_1	668	674	PF00069	0.656
MOD_CK1_1	679	685	PF00069	0.600
MOD_CK1_1	708	714	PF00069	0.581
MOD_CK1_1	756	762	PF00069	0.753
MOD_CK1_1	804	810	PF00069	0.714
MOD_CK1_1	834	840	PF00069	0.560
MOD_CK1_1	897	903	PF00069	0.714
MOD_CK1_1	92	98	PF00069	0.693
MOD_CMANNOS	548	551	PF00535	0.484
MOD_GlcNHglycan	115	118	PF01048	0.707
MOD_GlcNHglycan	137	140	PF01048	0.773
MOD_GlcNHglycan	172	175	PF01048	0.680
MOD_GlcNHglycan	204	207	PF01048	0.635
MOD_GlcNHglycan	237	240	PF01048	0.622
MOD_GlcNHglycan	268	271	PF01048	0.736
MOD_GlcNHglycan	334	337	PF01048	0.687
MOD_GlcNHglycan	348	351	PF01048	0.654
MOD_GlcNHglycan	36	39	PF01048	0.638
MOD_GlcNHglycan	367	370	PF01048	0.634
MOD_GlcNHglycan	376	379	PF01048	0.632
MOD_GlcNHglycan	384	387	PF01048	0.547
MOD_GlcNHglycan	425	428	PF01048	0.606
MOD_GlcNHglycan	530	533	PF01048	0.683
MOD_GlcNHglycan	554	557	PF01048	0.665
MOD_GlcNHglycan	575	578	PF01048	0.667
MOD_GlcNHglycan	646	649	PF01048	0.649
MOD_GlcNHglycan	651	654	PF01048	0.707
MOD_GlcNHglycan	667	670	PF01048	0.507
MOD_GlcNHglycan	683	686	PF01048	0.608
MOD_GlcNHglycan	696	699	PF01048	0.542
MOD_GlcNHglycan	701	704	PF01048	0.481
MOD_GlcNHglycan	720	723	PF01048	0.788
MOD_GlcNHglycan	727	730	PF01048	0.720
MOD_GlcNHglycan	739	742	PF01048	0.650
MOD_GlcNHglycan	771	774	PF01048	0.737
MOD_GlcNHglycan	775	778	PF01048	0.608
MOD_GlcNHglycan	803	806	PF01048	0.757
MOD_GlcNHglycan	81	84	PF01048	0.616
MOD_GlcNHglycan	814	817	PF01048	0.712
MOD_GlcNHglycan	891	894	PF01048	0.681
MOD_GlcNHglycan	895	899	PF01048	0.716
MOD_GlcNHglycan	917	920	PF01048	0.730
MOD_GSK3_1	109	116	PF00069	0.640
MOD_GSK3_1	135	142	PF00069	0.780
MOD_GSK3_1	166	173	PF00069	0.828
MOD_GSK3_1	182	189	PF00069	0.531
MOD_GSK3_1	242	249	PF00069	0.608
MOD_GSK3_1	277	284	PF00069	0.588
MOD_GSK3_1	300	307	PF00069	0.696
MOD_GSK3_1	332	339	PF00069	0.648
MOD_GSK3_1	363	370	PF00069	0.636
MOD_GSK3_1	373	380	PF00069	0.636
MOD_GSK3_1	394	401	PF00069	0.473
MOD_GSK3_1	519	526	PF00069	0.604
MOD_GSK3_1	564	571	PF00069	0.728
MOD_GSK3_1	587	594	PF00069	0.714
MOD_GSK3_1	607	614	PF00069	0.584
MOD_GSK3_1	639	646	PF00069	0.605
MOD_GSK3_1	708	715	PF00069	0.499
MOD_GSK3_1	752	759	PF00069	0.779
MOD_GSK3_1	763	770	PF00069	0.629
MOD_LATS_1	421	427	PF00433	0.525
MOD_LATS_1	609	615	PF00433	0.625
MOD_N-GLC_1	202	207	PF02516	0.731
MOD_N-GLC_1	423	428	PF02516	0.594
MOD_N-GLC_1	592	597	PF02516	0.647
MOD_N-GLC_1	644	649	PF02516	0.541
MOD_N-GLC_1	725	730	PF02516	0.581
MOD_NEK2_1	581	586	PF00069	0.617
MOD_NEK2_1	644	649	PF00069	0.618
MOD_NEK2_1	718	723	PF00069	0.624
MOD_NEK2_1	89	94	PF00069	0.565
MOD_PIKK_1	106	112	PF00454	0.658
MOD_PIKK_1	223	229	PF00454	0.627
MOD_PIKK_1	300	306	PF00454	0.580
MOD_PIKK_1	476	482	PF00454	0.471
MOD_PIKK_1	524	530	PF00454	0.703
MOD_PIKK_1	713	719	PF00454	0.631
MOD_PK_1	172	178	PF00069	0.683
MOD_PKA_1	611	617	PF00069	0.625
MOD_PKA_2	112	118	PF00069	0.563
MOD_PKA_2	135	141	PF00069	0.658
MOD_PKA_2	167	173	PF00069	0.678
MOD_PKA_2	358	364	PF00069	0.681
MOD_PKA_2	430	436	PF00069	0.779
MOD_PKA_2	484	490	PF00069	0.539
MOD_PKA_2	881	887	PF00069	0.517
MOD_PKA_2	90	96	PF00069	0.605
MOD_PKB_1	141	149	PF00069	0.576
MOD_PKB_1	443	451	PF00069	0.652
MOD_Plk_1	250	256	PF00069	0.631
MOD_Plk_1	271	277	PF00069	0.681
MOD_Plk_1	819	825	PF00069	0.549
MOD_Plk_2-3	398	404	PF00069	0.493
MOD_Plk_4	101	107	PF00069	0.612
MOD_Plk_4	214	220	PF00069	0.631
MOD_Plk_4	242	248	PF00069	0.630
MOD_Plk_4	250	256	PF00069	0.605
MOD_Plk_4	639	645	PF00069	0.629
MOD_Plk_4	705	711	PF00069	0.608
MOD_Plk_4	794	800	PF00069	0.536
MOD_Plk_4	881	887	PF00069	0.517
MOD_ProDKin_1	177	183	PF00069	0.727
MOD_ProDKin_1	190	196	PF00069	0.563
MOD_ProDKin_1	2	8	PF00069	0.615
MOD_ProDKin_1	217	223	PF00069	0.662
MOD_ProDKin_1	237	243	PF00069	0.762
MOD_ProDKin_1	282	288	PF00069	0.668
MOD_ProDKin_1	308	314	PF00069	0.607
MOD_ProDKin_1	339	345	PF00069	0.626
MOD_ProDKin_1	369	375	PF00069	0.765
MOD_ProDKin_1	37	43	PF00069	0.667
MOD_ProDKin_1	431	437	PF00069	0.680
MOD_ProDKin_1	519	525	PF00069	0.707
MOD_ProDKin_1	679	685	PF00069	0.664
MOD_ProDKin_1	742	748	PF00069	0.653
MOD_ProDKin_1	753	759	PF00069	0.705
MOD_ProDKin_1	836	842	PF00069	0.618
MOD_ProDKin_1	897	903	PF00069	0.664
MOD_ProDKin_1	909	915	PF00069	0.795
TRG_DiLeu_BaLyEn_6	22	27	PF01217	0.637
TRG_DiLeu_BaLyEn_6	465	470	PF01217	0.418
TRG_ENDOCYTIC_2	677	680	PF00928	0.689
TRG_ER_diArg_1	128	131	PF00400	0.698
TRG_ER_diArg_1	141	144	PF00400	0.643
TRG_ER_diArg_1	158	160	PF00400	0.664
TRG_ER_diArg_1	442	445	PF00400	0.684
TRG_Pf-PMV_PEXEL_1	415	419	PF00026	0.457
TRG_Pf-PMV_PEXEL_1	468	472	PF00026	0.474
TRG_Pf-PMV_PEXEL_1	59	63	PF00026	0.455
TRG_Pf-PMV_PEXEL_1	869	873	PF00026	0.465

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I094	Leptomonas seymouri	35%	85%
A0A3S5H766	Leishmania donovani	84%	98%
A4HA64	Leishmania braziliensis	61%	99%
A4HYD5	Leishmania infantum	84%	94%
E9AS68	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	93%