LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QD74_LEIMA
TriTrypDb:
LmjF.19.1365 , LMJLV39_190020000 * , LMJSD75_190018900 *
Length:
124

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 15
NetGPI no yes: 0, no: 15
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QD74
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QD74

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 4 6 PF00675 0.531
CLV_PCSK_KEX2_1 4 6 PF00082 0.534
CLV_PCSK_SKI1_1 4 8 PF00082 0.510
DEG_Nend_Nbox_1 1 3 PF02207 0.550
DEG_SCF_FBW7_1 99 105 PF00400 0.438
DOC_CKS1_1 99 104 PF01111 0.441
DOC_USP7_MATH_1 102 106 PF00917 0.548
DOC_USP7_MATH_1 37 41 PF00917 0.599
DOC_WW_Pin1_4 63 68 PF00397 0.513
DOC_WW_Pin1_4 98 103 PF00397 0.635
LIG_14-3-3_CanoR_1 114 124 PF00244 0.421
LIG_14-3-3_CanoR_1 5 11 PF00244 0.528
LIG_BRCT_BRCA1_1 86 90 PF00533 0.572
LIG_FHA_1 44 50 PF00498 0.575
LIG_FHA_1 94 100 PF00498 0.494
LIG_LIR_Gen_1 105 110 PF02991 0.539
LIG_LIR_Nem_3 105 109 PF02991 0.599
LIG_LIR_Nem_3 87 93 PF02991 0.566
LIG_MYND_1 33 37 PF01753 0.547
LIG_PDZ_Class_2 119 124 PF00595 0.433
LIG_Pex14_2 106 110 PF04695 0.458
LIG_SH3_3 86 92 PF00018 0.605
LIG_SH3_3 96 102 PF00018 0.504
LIG_SUMO_SIM_par_1 95 101 PF11976 0.455
LIG_TRAF2_1 69 72 PF00917 0.575
LIG_WRC_WIRS_1 103 108 PF05994 0.462
MOD_CK1_1 63 69 PF00069 0.555
MOD_CK1_1 81 87 PF00069 0.391
MOD_CK1_1 98 104 PF00069 0.488
MOD_CK2_1 102 108 PF00069 0.464
MOD_CK2_1 66 72 PF00069 0.683
MOD_Cter_Amidation 2 5 PF01082 0.564
MOD_GlcNHglycan 78 81 PF01048 0.593
MOD_GlcNHglycan 8 11 PF01048 0.464
MOD_GSK3_1 38 45 PF00069 0.617
MOD_GSK3_1 48 55 PF00069 0.582
MOD_GSK3_1 76 83 PF00069 0.543
MOD_GSK3_1 93 100 PF00069 0.520
MOD_NEK2_1 117 122 PF00069 0.588
MOD_NEK2_1 38 43 PF00069 0.525
MOD_NEK2_1 78 83 PF00069 0.635
MOD_NEK2_1 95 100 PF00069 0.584
MOD_PIKK_1 48 54 PF00454 0.594
MOD_PKA_2 43 49 PF00069 0.500
MOD_Plk_1 71 77 PF00069 0.478
MOD_Plk_4 102 108 PF00069 0.499
MOD_Plk_4 84 90 PF00069 0.476
MOD_ProDKin_1 63 69 PF00069 0.510
MOD_ProDKin_1 98 104 PF00069 0.637
TRG_ER_diArg_1 4 6 PF00400 0.532

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3I1 Leptomonas seymouri 64% 100%
A0A1X0P784 Trypanosomatidae 32% 100%
A0A3Q8IBH0 Leishmania donovani 53% 100%
A0A3S7WVJ6 Leishmania donovani 93% 76%
A0A422NUN3 Trypanosoma rangeli 44% 100%
A4HA86 Leishmania braziliensis 74% 100%
A4HA99 Leishmania braziliensis 41% 100%
A4HF75 Leishmania braziliensis 40% 100%
A4HYG5 Leishmania infantum 93% 76%
E9AHU8 Leishmania infantum 52% 100%
E9AS83 Leishmania mexicana (strain MHOM/GT/2001/U1103) 51% 100%
E9AS90 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
Q4QD83 Leishmania major 51% 100%
V5D1C6 Trypanosoma cruzi 43% 91%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS