LeishMANIAdb
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CHCH domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
CHCH domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4QD64_LEIMA
TriTrypDb:
LmjF.19.1460 , LMJLV39_190021100 , LMJSD75_190020800
Length:
116

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QD64
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QD64

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 101 103 PF00675 0.482
CLV_NRD_NRD_1 8 10 PF00675 0.495
CLV_PCSK_KEX2_1 100 102 PF00082 0.456
CLV_PCSK_KEX2_1 8 10 PF00082 0.495
CLV_PCSK_PC1ET2_1 100 102 PF00082 0.499
DOC_MAPK_gen_1 100 109 PF00069 0.531
DOC_MAPK_MEF2A_6 100 109 PF00069 0.391
DOC_PP1_RVXF_1 7 14 PF00149 0.536
LIG_eIF4E_1 57 63 PF01652 0.508
LIG_FHA_1 24 30 PF00498 0.637
LIG_LIR_Nem_3 73 78 PF02991 0.479
LIG_Pex14_2 59 63 PF04695 0.492
LIG_PTB_Apo_2 51 58 PF02174 0.574
LIG_PTB_Phospho_1 51 57 PF10480 0.573
LIG_SH2_STAT5 20 23 PF00017 0.512
LIG_SH2_STAT5 6 9 PF00017 0.524
LIG_SH2_STAT5 85 88 PF00017 0.432
LIG_SH3_3 39 45 PF00018 0.449
LIG_SUMO_SIM_anti_2 106 111 PF11976 0.424
LIG_UBA3_1 92 100 PF00899 0.481
MOD_Plk_4 2 8 PF00069 0.517
MOD_SUMO_rev_2 47 52 PF00179 0.522
TRG_ER_diArg_1 101 104 PF00400 0.485
TRG_ER_diArg_1 7 9 PF00400 0.515

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PE55 Leptomonas seymouri 84% 98%
A0A0S4KEM4 Bodo saltans 56% 97%
A0A1X0P7F3 Trypanosomatidae 68% 94%
A0A3R7NNX8 Trypanosoma rangeli 68% 100%
A4HA96 Leishmania braziliensis 91% 99%
A4HYH6 Leishmania infantum 96% 99%
D0A0V1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 62% 100%
E9ASA0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 99%
Q9BID8 Leishmania donovani 96% 99%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS