BRCA-2_OB1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA repair protein BRCA2, putative

Species:

Leishmania major

UniProt:

Q4QD38_LEIMA

TriTrypDb:

LmjF.20.0060 , LMJLV39_200005500 , LMJSD75_200005500

Length:

1165

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0005654	nucleoplasm	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4QD38

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QD38

PDB structure(s): 7qv8_D

Function

Biological processes
Term	Name	Level	Count
GO:0000724	double-strand break repair via homologous recombination	7	11
GO:0000725	recombinational repair	6	11
GO:0006139	nucleobase-containing compound metabolic process	3	11
GO:0006259	DNA metabolic process	4	11
GO:0006281	DNA repair	5	11
GO:0006302	double-strand break repair	6	11
GO:0006310	DNA recombination	5	11
GO:0006355	regulation of DNA-templated transcription	6	2
GO:0006725	cellular aromatic compound metabolic process	3	11
GO:0006807	nitrogen compound metabolic process	2	11
GO:0006950	response to stress	2	11
GO:0006974	DNA damage response	4	11
GO:0008152	metabolic process	1	11
GO:0009605	response to external stimulus	2	2
GO:0009607	response to biotic stimulus	2	2
GO:0009889	regulation of biosynthetic process	4	2
GO:0009987	cellular process	1	11
GO:0010468	regulation of gene expression	5	2
GO:0010556	regulation of macromolecule biosynthetic process	5	2
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	2
GO:0019222	regulation of metabolic process	3	2
GO:0020033	antigenic variation	7	2
GO:0031323	regulation of cellular metabolic process	4	2
GO:0031326	regulation of cellular biosynthetic process	5	2
GO:0033554	cellular response to stress	3	11
GO:0034641	cellular nitrogen compound metabolic process	3	11
GO:0042783	evasion of host immune response	6	2
GO:0043170	macromolecule metabolic process	3	11
GO:0043207	response to external biotic stimulus	3	2
GO:0044237	cellular metabolic process	2	11
GO:0044238	primary metabolic process	2	11
GO:0044260	obsolete cellular macromolecule metabolic process	3	11
GO:0044403	biological process involved in symbiotic interaction	2	2
GO:0044419	biological process involved in interspecies interaction between organisms	1	2
GO:0046483	heterocycle metabolic process	3	11
GO:0050789	regulation of biological process	2	2
GO:0050794	regulation of cellular process	3	2
GO:0050896	response to stimulus	1	11
GO:0051171	regulation of nitrogen compound metabolic process	4	2
GO:0051252	regulation of RNA metabolic process	5	2
GO:0051701	biological process involved in interaction with host	3	2
GO:0051707	response to other organism	2	2
GO:0051716	cellular response to stimulus	2	11
GO:0052173	response to defenses of other organism	3	2
GO:0052200	response to host defenses	4	2
GO:0052572	response to host immune response	5	2
GO:0060255	regulation of macromolecule metabolic process	4	2
GO:0065007	biological regulation	1	2
GO:0071704	organic substance metabolic process	2	11
GO:0075136	response to host	3	2
GO:0080090	regulation of primary metabolic process	4	2
GO:0090304	nucleic acid metabolic process	4	11
GO:1901360	organic cyclic compound metabolic process	3	11
GO:1903506	regulation of nucleic acid-templated transcription	7	2
GO:2001141	regulation of RNA biosynthetic process	6	2

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	2
GO:0003677	DNA binding	4	2
GO:0003684	damaged DNA binding	5	2
GO:0005488	binding	1	2
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	460	464	PF00656	0.536
CLV_C14_Caspase3-7	613	617	PF00656	0.438
CLV_C14_Caspase3-7	873	877	PF00656	0.592
CLV_NRD_NRD_1	1020	1022	PF00675	0.315
CLV_NRD_NRD_1	1083	1085	PF00675	0.524
CLV_NRD_NRD_1	124	126	PF00675	0.336
CLV_NRD_NRD_1	269	271	PF00675	0.618
CLV_NRD_NRD_1	27	29	PF00675	0.500
CLV_NRD_NRD_1	426	428	PF00675	0.336
CLV_NRD_NRD_1	45	47	PF00675	0.497
CLV_NRD_NRD_1	608	610	PF00675	0.514
CLV_NRD_NRD_1	696	698	PF00675	0.481
CLV_NRD_NRD_1	712	714	PF00675	0.413
CLV_NRD_NRD_1	846	848	PF00675	0.446
CLV_NRD_NRD_1	995	997	PF00675	0.530
CLV_PCSK_FUR_1	606	610	PF00082	0.510
CLV_PCSK_KEX2_1	1020	1022	PF00082	0.419
CLV_PCSK_KEX2_1	1083	1085	PF00082	0.465
CLV_PCSK_KEX2_1	124	126	PF00082	0.336
CLV_PCSK_KEX2_1	163	165	PF00082	0.617
CLV_PCSK_KEX2_1	269	271	PF00082	0.644
CLV_PCSK_KEX2_1	29	31	PF00082	0.508
CLV_PCSK_KEX2_1	608	610	PF00082	0.591
CLV_PCSK_KEX2_1	712	714	PF00082	0.495
CLV_PCSK_KEX2_1	995	997	PF00082	0.504
CLV_PCSK_PC1ET2_1	163	165	PF00082	0.489
CLV_PCSK_PC1ET2_1	29	31	PF00082	0.502
CLV_PCSK_PC7_1	25	31	PF00082	0.505
CLV_PCSK_SKI1_1	1093	1097	PF00082	0.470
CLV_PCSK_SKI1_1	119	123	PF00082	0.297
CLV_PCSK_SKI1_1	157	161	PF00082	0.636
CLV_PCSK_SKI1_1	312	316	PF00082	0.570
CLV_PCSK_SKI1_1	376	380	PF00082	0.396
CLV_PCSK_SKI1_1	423	427	PF00082	0.299
CLV_PCSK_SKI1_1	457	461	PF00082	0.289
CLV_PCSK_SKI1_1	497	501	PF00082	0.263
CLV_PCSK_SKI1_1	589	593	PF00082	0.537
CLV_PCSK_SKI1_1	651	655	PF00082	0.554
CLV_PCSK_SKI1_1	691	695	PF00082	0.414
CLV_PCSK_SKI1_1	824	828	PF00082	0.460
CLV_Separin_Metazoa	1145	1149	PF03568	0.489
DEG_APCC_DBOX_1	124	132	PF00400	0.496
DEG_APCC_DBOX_1	422	430	PF00400	0.279
DEG_APCC_DBOX_1	780	788	PF00400	0.470
DEG_COP1_1	142	150	PF00400	0.552
DEG_COP1_1	873	883	PF00400	0.608
DEG_SCF_FBW7_1	314	319	PF00400	0.409
DEG_SCF_FBW7_2	235	242	PF00400	0.543
DEG_SPOP_SBC_1	83	87	PF00917	0.534
DOC_ANK_TNKS_1	426	433	PF00023	0.475
DOC_CDC14_PxL_1	102	110	PF14671	0.587
DOC_CKS1_1	39	44	PF01111	0.544
DOC_CKS1_1	527	532	PF01111	0.557
DOC_CKS1_1	938	943	PF01111	0.714
DOC_CYCLIN_RxL_1	767	778	PF00134	0.479
DOC_CYCLIN_yClb5_NLxxxL_5	923	932	PF00134	0.502
DOC_CYCLIN_yCln2_LP_2	1001	1007	PF00134	0.594
DOC_CYCLIN_yCln2_LP_2	1101	1107	PF00134	0.475
DOC_CYCLIN_yCln2_LP_2	539	545	PF00134	0.456
DOC_CYCLIN_yCln2_LP_2	938	944	PF00134	0.585
DOC_MAPK_DCC_7	875	885	PF00069	0.605
DOC_MAPK_gen_1	1083	1090	PF00069	0.500
DOC_MAPK_gen_1	17	26	PF00069	0.518
DOC_MAPK_gen_1	448	458	PF00069	0.468
DOC_MAPK_MEF2A_6	17	26	PF00069	0.572
DOC_MAPK_RevD_3	1069	1084	PF00069	0.445
DOC_PP1_RVXF_1	1076	1083	PF00149	0.442
DOC_PP1_RVXF_1	383	389	PF00149	0.291
DOC_PP1_RVXF_1	689	695	PF00149	0.468
DOC_PP2B_LxvP_1	138	141	PF13499	0.569
DOC_PP2B_LxvP_1	539	542	PF13499	0.457
DOC_PP2B_LxvP_1	761	764	PF13499	0.478
DOC_PP2B_LxvP_1	772	775	PF13499	0.386
DOC_PP2B_LxvP_1	80	83	PF13499	0.563
DOC_PP4_FxxP_1	11	14	PF00568	0.528
DOC_PP4_FxxP_1	272	275	PF00568	0.623
DOC_PP4_MxPP_1	205	208	PF00568	0.519
DOC_USP7_MATH_1	1007	1011	PF00917	0.646
DOC_USP7_MATH_1	169	173	PF00917	0.646
DOC_USP7_MATH_1	182	186	PF00917	0.783
DOC_USP7_MATH_1	316	320	PF00917	0.431
DOC_USP7_MATH_1	378	382	PF00917	0.410
DOC_USP7_MATH_1	396	400	PF00917	0.337
DOC_USP7_MATH_1	40	44	PF00917	0.603
DOC_USP7_MATH_1	50	54	PF00917	0.587
DOC_USP7_MATH_1	619	623	PF00917	0.512
DOC_USP7_MATH_1	677	681	PF00917	0.461
DOC_USP7_MATH_1	764	768	PF00917	0.428
DOC_USP7_MATH_1	83	87	PF00917	0.703
DOC_USP7_MATH_1	894	898	PF00917	0.714
DOC_USP7_MATH_1	967	971	PF00917	0.695
DOC_WW_Pin1_4	1100	1105	PF00397	0.606
DOC_WW_Pin1_4	189	194	PF00397	0.786
DOC_WW_Pin1_4	235	240	PF00397	0.628
DOC_WW_Pin1_4	312	317	PF00397	0.535
DOC_WW_Pin1_4	35	40	PF00397	0.672
DOC_WW_Pin1_4	363	368	PF00397	0.428
DOC_WW_Pin1_4	399	404	PF00397	0.439
DOC_WW_Pin1_4	450	455	PF00397	0.536
DOC_WW_Pin1_4	46	51	PF00397	0.655
DOC_WW_Pin1_4	52	57	PF00397	0.601
DOC_WW_Pin1_4	526	531	PF00397	0.486
DOC_WW_Pin1_4	73	78	PF00397	0.684
DOC_WW_Pin1_4	892	897	PF00397	0.740
DOC_WW_Pin1_4	899	904	PF00397	0.778
DOC_WW_Pin1_4	937	942	PF00397	0.672
LIG_14-3-3_CanoR_1	1093	1101	PF00244	0.435
LIG_14-3-3_CanoR_1	1151	1159	PF00244	0.567
LIG_14-3-3_CanoR_1	155	160	PF00244	0.682
LIG_14-3-3_CanoR_1	213	218	PF00244	0.755
LIG_14-3-3_CanoR_1	457	462	PF00244	0.533
LIG_14-3-3_CanoR_1	589	595	PF00244	0.562
LIG_14-3-3_CanoR_1	627	632	PF00244	0.327
LIG_14-3-3_CanoR_1	770	775	PF00244	0.498
LIG_14-3-3_CanoR_1	781	785	PF00244	0.470
LIG_14-3-3_CanoR_1	817	823	PF00244	0.474
LIG_Actin_WH2_2	1135	1150	PF00022	0.438
LIG_Actin_WH2_2	454	471	PF00022	0.536
LIG_Actin_WH2_2	472	488	PF00022	0.442
LIG_BIR_III_2	36	40	PF00653	0.629
LIG_BIR_III_2	838	842	PF00653	0.479
LIG_BRCT_BRCA1_1	324	328	PF00533	0.504
LIG_CSL_BTD_1	1116	1119	PF09270	0.478
LIG_CSL_BTD_1	997	1000	PF09270	0.543
LIG_CtBP_PxDLS_1	542	546	PF00389	0.502
LIG_deltaCOP1_diTrp_1	1113	1122	PF00928	0.384
LIG_FHA_1	1000	1006	PF00498	0.553
LIG_FHA_1	1035	1041	PF00498	0.498
LIG_FHA_1	156	162	PF00498	0.526
LIG_FHA_1	224	230	PF00498	0.795
LIG_FHA_1	294	300	PF00498	0.650
LIG_FHA_1	356	362	PF00498	0.331
LIG_FHA_1	403	409	PF00498	0.475
LIG_FHA_1	469	475	PF00498	0.485
LIG_FHA_1	602	608	PF00498	0.534
LIG_FHA_1	627	633	PF00498	0.351
LIG_FHA_1	722	728	PF00498	0.553
LIG_FHA_1	745	751	PF00498	0.383
LIG_FHA_1	755	761	PF00498	0.407
LIG_FHA_1	777	783	PF00498	0.404
LIG_FHA_1	810	816	PF00498	0.359
LIG_FHA_1	899	905	PF00498	0.584
LIG_FHA_1	927	933	PF00498	0.579
LIG_FHA_2	1046	1052	PF00498	0.539
LIG_FHA_2	147	153	PF00498	0.615
LIG_FHA_2	31	37	PF00498	0.672
LIG_FHA_2	458	464	PF00498	0.536
LIG_FHA_2	505	511	PF00498	0.536
LIG_FHA_2	53	59	PF00498	0.647
LIG_FHA_2	645	651	PF00498	0.555
LIG_FHA_2	791	797	PF00498	0.503
LIG_FHA_2	871	877	PF00498	0.732
LIG_Integrin_isoDGR_2	920	922	PF01839	0.523
LIG_LIR_Apic_2	10	14	PF02991	0.604
LIG_LIR_Apic_2	1113	1119	PF02991	0.388
LIG_LIR_Gen_1	516	526	PF02991	0.553
LIG_LIR_Gen_1	666	677	PF02991	0.472
LIG_LIR_Gen_1	747	753	PF02991	0.348
LIG_LIR_Gen_1	756	766	PF02991	0.348
LIG_LIR_Gen_1	810	815	PF02991	0.358
LIG_LIR_LC3C_4	436	441	PF02991	0.476
LIG_LIR_LC3C_4	783	786	PF02991	0.348
LIG_LIR_Nem_3	1089	1095	PF02991	0.335
LIG_LIR_Nem_3	399	404	PF02991	0.452
LIG_LIR_Nem_3	516	522	PF02991	0.553
LIG_LIR_Nem_3	666	672	PF02991	0.532
LIG_LIR_Nem_3	747	751	PF02991	0.399
LIG_LIR_Nem_3	756	761	PF02991	0.313
LIG_LIR_Nem_3	810	814	PF02991	0.335
LIG_LIR_Nem_3	850	855	PF02991	0.518
LIG_LIR_Nem_3	976	982	PF02991	0.388
LIG_MYND_1	106	110	PF01753	0.563
LIG_NRBOX	338	344	PF00104	0.381
LIG_Pex14_1	1091	1095	PF04695	0.460
LIG_Pex14_1	669	673	PF04695	0.470
LIG_PTB_Apo_2	752	759	PF02174	0.401
LIG_PTB_Apo_2	785	792	PF02174	0.328
LIG_PTB_Phospho_1	752	758	PF10480	0.405
LIG_Rb_pABgroove_1	983	991	PF01858	0.508
LIG_REV1ctd_RIR_1	691	702	PF16727	0.491
LIG_SH2_CRK	519	523	PF00017	0.536
LIG_SH2_CRK	758	762	PF00017	0.434
LIG_SH2_CRK	811	815	PF00017	0.371
LIG_SH2_CRK	979	983	PF00017	0.480
LIG_SH2_SRC	701	704	PF00017	0.573
LIG_SH2_STAP1	811	815	PF00017	0.390
LIG_SH2_STAT5	1139	1142	PF00017	0.341
LIG_SH2_STAT5	701	704	PF00017	0.493
LIG_SH2_STAT5	737	740	PF00017	0.507
LIG_SH2_STAT5	811	814	PF00017	0.404
LIG_SH2_STAT5	915	918	PF00017	0.683
LIG_SH3_1	875	881	PF00018	0.507
LIG_SH3_2	39	44	PF14604	0.544
LIG_SH3_3	104	110	PF00018	0.509
LIG_SH3_3	195	201	PF00018	0.686
LIG_SH3_3	36	42	PF00018	0.659
LIG_SH3_3	481	487	PF00018	0.497
LIG_SH3_3	875	881	PF00018	0.610
LIG_SH3_3	91	97	PF00018	0.723
LIG_SH3_3	928	934	PF00018	0.706
LIG_SH3_3	938	944	PF00018	0.687
LIG_SH3_3	957	963	PF00018	0.746
LIG_Sin3_3	437	444	PF02671	0.461
LIG_SUMO_SIM_anti_2	296	303	PF11976	0.456
LIG_SUMO_SIM_anti_2	319	325	PF11976	0.392
LIG_SUMO_SIM_anti_2	402	408	PF11976	0.390
LIG_SUMO_SIM_anti_2	438	443	PF11976	0.442
LIG_SUMO_SIM_anti_2	629	636	PF11976	0.485
LIG_SUMO_SIM_anti_2	778	786	PF11976	0.486
LIG_SUMO_SIM_par_1	341	346	PF11976	0.303
LIG_SUMO_SIM_par_1	457	463	PF11976	0.536
LIG_SUMO_SIM_par_1	629	636	PF11976	0.486
LIG_TRAF2_1	1055	1058	PF00917	0.442
LIG_TYR_ITIM	517	522	PF00017	0.410
LIG_UBA3_1	322	331	PF00899	0.290
LIG_UBA3_1	359	368	PF00899	0.381
LIG_WRC_WIRS_1	327	332	PF05994	0.376
LIG_WRC_WIRS_1	564	569	PF05994	0.480
MOD_CDK_SPK_2	363	368	PF00069	0.413
MOD_CDK_SPxK_1	38	44	PF00069	0.656
MOD_CDK_SPxxK_3	450	457	PF00069	0.342
MOD_CK1_1	1029	1035	PF00069	0.594
MOD_CK1_1	114	120	PF00069	0.371
MOD_CK1_1	172	178	PF00069	0.649
MOD_CK1_1	253	259	PF00069	0.603
MOD_CK1_1	321	327	PF00069	0.446
MOD_CK1_1	38	44	PF00069	0.699
MOD_CK1_1	399	405	PF00069	0.434
MOD_CK1_1	435	441	PF00069	0.355
MOD_CK1_1	51	57	PF00069	0.610
MOD_CK1_1	626	632	PF00069	0.341
MOD_CK1_1	668	674	PF00069	0.430
MOD_CK1_1	85	91	PF00069	0.638
MOD_CK1_1	952	958	PF00069	0.671
MOD_CK2_1	1045	1051	PF00069	0.443
MOD_CK2_1	1155	1161	PF00069	0.574
MOD_CK2_1	146	152	PF00069	0.615
MOD_CK2_1	248	254	PF00069	0.665
MOD_CK2_1	343	349	PF00069	0.578
MOD_CK2_1	443	449	PF00069	0.286
MOD_CK2_1	504	510	PF00069	0.331
MOD_CK2_1	52	58	PF00069	0.644
MOD_CK2_1	644	650	PF00069	0.478
MOD_Cter_Amidation	44	47	PF01082	0.656
MOD_DYRK1A_RPxSP_1	312	316	PF00069	0.439
MOD_GlcNHglycan	1009	1012	PF01048	0.591
MOD_GlcNHglycan	1028	1031	PF01048	0.598
MOD_GlcNHglycan	1129	1132	PF01048	0.457
MOD_GlcNHglycan	1142	1145	PF01048	0.479
MOD_GlcNHglycan	116	119	PF01048	0.321
MOD_GlcNHglycan	184	187	PF01048	0.645
MOD_GlcNHglycan	189	192	PF01048	0.649
MOD_GlcNHglycan	344	348	PF01048	0.486
MOD_GlcNHglycan	380	383	PF01048	0.432
MOD_GlcNHglycan	393	396	PF01048	0.624
MOD_GlcNHglycan	398	401	PF01048	0.521
MOD_GlcNHglycan	435	438	PF01048	0.411
MOD_GlcNHglycan	575	579	PF01048	0.660
MOD_GlcNHglycan	766	769	PF01048	0.551
MOD_GlcNHglycan	89	92	PF01048	0.704
MOD_GlcNHglycan	896	899	PF01048	0.783
MOD_GlcNHglycan	934	937	PF01048	0.627
MOD_GlcNHglycan	951	954	PF01048	0.789
MOD_GSK3_1	1041	1048	PF00069	0.531
MOD_GSK3_1	1069	1076	PF00069	0.469
MOD_GSK3_1	108	115	PF00069	0.291
MOD_GSK3_1	1093	1100	PF00069	0.381
MOD_GSK3_1	1151	1158	PF00069	0.538
MOD_GSK3_1	146	153	PF00069	0.562
MOD_GSK3_1	242	249	PF00069	0.755
MOD_GSK3_1	293	300	PF00069	0.537
MOD_GSK3_1	310	317	PF00069	0.354
MOD_GSK3_1	318	325	PF00069	0.381
MOD_GSK3_1	326	333	PF00069	0.386
MOD_GSK3_1	343	350	PF00069	0.399
MOD_GSK3_1	387	394	PF00069	0.430
MOD_GSK3_1	46	53	PF00069	0.759
MOD_GSK3_1	563	570	PF00069	0.440
MOD_GSK3_1	619	626	PF00069	0.451
MOD_GSK3_1	716	723	PF00069	0.555
MOD_GSK3_1	776	783	PF00069	0.408
MOD_GSK3_1	83	90	PF00069	0.679
MOD_GSK3_1	866	873	PF00069	0.693
MOD_GSK3_1	894	901	PF00069	0.613
MOD_LATS_1	1149	1155	PF00433	0.511
MOD_LATS_1	211	217	PF00433	0.563
MOD_LATS_1	455	461	PF00433	0.406
MOD_N-GLC_1	720	725	PF02516	0.625
MOD_N-GLC_1	754	759	PF02516	0.410
MOD_N-GLC_1	787	792	PF02516	0.331
MOD_N-GLC_1	926	931	PF02516	0.504
MOD_NEK2_1	1005	1010	PF00069	0.599
MOD_NEK2_1	1095	1100	PF00069	0.358
MOD_NEK2_1	112	117	PF00069	0.279
MOD_NEK2_1	1138	1143	PF00069	0.386
MOD_NEK2_1	150	155	PF00069	0.580
MOD_NEK2_1	248	253	PF00069	0.778
MOD_NEK2_1	293	298	PF00069	0.608
MOD_NEK2_1	322	327	PF00069	0.475
MOD_NEK2_1	343	348	PF00069	0.445
MOD_NEK2_1	442	447	PF00069	0.308
MOD_NEK2_1	692	697	PF00069	0.443
MOD_NEK2_1	787	792	PF00069	0.463
MOD_NEK2_1	815	820	PF00069	0.532
MOD_NEK2_1	866	871	PF00069	0.776
MOD_NEK2_2	443	448	PF00069	0.311
MOD_PIKK_1	64	70	PF00454	0.646
MOD_PIKK_1	816	822	PF00454	0.509
MOD_PKA_1	124	130	PF00069	0.410
MOD_PKA_2	1026	1032	PF00069	0.567
MOD_PKA_2	124	130	PF00069	0.410
MOD_PKA_2	277	283	PF00069	0.783
MOD_PKA_2	626	632	PF00069	0.348
MOD_PKA_2	780	786	PF00069	0.402
MOD_PKA_2	816	822	PF00069	0.509
MOD_PKB_1	213	221	PF00069	0.594
MOD_PKB_1	28	36	PF00069	0.586
MOD_Plk_1	1040	1046	PF00069	0.509
MOD_Plk_1	1069	1075	PF00069	0.480
MOD_Plk_1	253	259	PF00069	0.598
MOD_Plk_1	30	36	PF00069	0.567
MOD_Plk_1	754	760	PF00069	0.404
MOD_Plk_1	787	793	PF00069	0.375
MOD_Plk_1	809	815	PF00069	0.398
MOD_Plk_2-3	1155	1161	PF00069	0.482
MOD_Plk_4	1041	1047	PF00069	0.470
MOD_Plk_4	1058	1064	PF00069	0.520
MOD_Plk_4	108	114	PF00069	0.279
MOD_Plk_4	1086	1092	PF00069	0.399
MOD_Plk_4	146	152	PF00069	0.514
MOD_Plk_4	297	303	PF00069	0.591
MOD_Plk_4	318	324	PF00069	0.494
MOD_Plk_4	355	361	PF00069	0.351
MOD_Plk_4	402	408	PF00069	0.363
MOD_Plk_4	435	441	PF00069	0.279
MOD_Plk_4	495	501	PF00069	0.361
MOD_Plk_4	541	547	PF00069	0.473
MOD_Plk_4	563	569	PF00069	0.427
MOD_Plk_4	627	633	PF00069	0.363
MOD_Plk_4	665	671	PF00069	0.373
MOD_Plk_4	7	13	PF00069	0.560
MOD_Plk_4	780	786	PF00069	0.385
MOD_Plk_4	787	793	PF00069	0.334
MOD_Plk_4	942	948	PF00069	0.585
MOD_ProDKin_1	1100	1106	PF00069	0.609
MOD_ProDKin_1	189	195	PF00069	0.786
MOD_ProDKin_1	235	241	PF00069	0.630
MOD_ProDKin_1	312	318	PF00069	0.525
MOD_ProDKin_1	35	41	PF00069	0.676
MOD_ProDKin_1	363	369	PF00069	0.430
MOD_ProDKin_1	399	405	PF00069	0.439
MOD_ProDKin_1	450	456	PF00069	0.410
MOD_ProDKin_1	46	52	PF00069	0.650
MOD_ProDKin_1	526	532	PF00069	0.340
MOD_ProDKin_1	73	79	PF00069	0.681
MOD_ProDKin_1	892	898	PF00069	0.742
MOD_ProDKin_1	899	905	PF00069	0.778
MOD_ProDKin_1	937	943	PF00069	0.675
TRG_DiLeu_BaEn_1	780	785	PF01217	0.375
TRG_DiLeu_BaEn_4	1041	1047	PF01217	0.394
TRG_DiLeu_BaLyEn_6	1148	1153	PF01217	0.503
TRG_DiLeu_BaLyEn_6	22	27	PF01217	0.559
TRG_ENDOCYTIC_2	1139	1142	PF00928	0.341
TRG_ENDOCYTIC_2	519	522	PF00928	0.410
TRG_ENDOCYTIC_2	758	761	PF00928	0.342
TRG_ENDOCYTIC_2	811	814	PF00928	0.367
TRG_ENDOCYTIC_2	979	982	PF00928	0.480
TRG_ER_diArg_1	1019	1021	PF00400	0.336
TRG_ER_diArg_1	1082	1084	PF00400	0.439
TRG_ER_diArg_1	123	125	PF00400	0.353
TRG_ER_diArg_1	212	215	PF00400	0.745
TRG_ER_diArg_1	27	30	PF00400	0.500
TRG_ER_diArg_1	587	590	PF00400	0.564
TRG_ER_diArg_1	606	609	PF00400	0.315
TRG_ER_diArg_1	711	713	PF00400	0.515
TRG_Pf-PMV_PEXEL_1	1151	1155	PF00026	0.493
TRG_Pf-PMV_PEXEL_1	215	219	PF00026	0.578
TRG_Pf-PMV_PEXEL_1	651	656	PF00026	0.570
TRG_Pf-PMV_PEXEL_1	834	838	PF00026	0.467
TRG_Pf-PMV_PEXEL_1	853	857	PF00026	0.444

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAP2	Leptomonas seymouri	51%	95%
A0A1X0NWJ4	Trypanosomatidae	27%	100%
A0A3S7WVQ6	Leishmania donovani	91%	100%
A0A422N7U4	Trypanosoma rangeli	30%	100%
A4HBH5	Leishmania braziliensis	74%	99%
A4HYJ9	Leishmania infantum	91%	100%
C9ZHU4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	100%
E9AUE6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
V5BQX8	Trypanosoma cruzi	29%	100%