| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 11 |
| NetGPI | no | yes: 0, no: 11 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005737 | cytoplasm | 2 | 2 |
| GO:0110165 | cellular anatomical entity | 1 | 2 |
Related structures:
AlphaFold database: Q4QD19
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006807 | nitrogen compound metabolic process | 2 | 12 |
| GO:0008152 | metabolic process | 1 | 12 |
| GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine | 3 | 12 |
| GO:0009058 | biosynthetic process | 2 | 12 |
| GO:0018193 | peptidyl-amino acid modification | 5 | 12 |
| GO:0018205 | peptidyl-lysine modification | 6 | 12 |
| GO:0019538 | protein metabolic process | 3 | 12 |
| GO:0036211 | protein modification process | 4 | 12 |
| GO:0043170 | macromolecule metabolic process | 3 | 12 |
| GO:0043412 | macromolecule modification | 4 | 12 |
| GO:0044238 | primary metabolic process | 2 | 12 |
| GO:0051604 | protein maturation | 4 | 12 |
| GO:0071704 | organic substance metabolic process | 2 | 12 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 12 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003824 | catalytic activity | 1 | 6 |
| GO:0016740 | transferase activity | 2 | 6 |
| GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups | 3 | 6 |
| GO:0034038 | deoxyhypusine synthase activity | 4 | 6 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 170 | 172 | PF00675 | 0.273 |
| CLV_NRD_NRD_1 | 19 | 21 | PF00675 | 0.741 |
| CLV_NRD_NRD_1 | 284 | 286 | PF00675 | 0.389 |
| CLV_PCSK_KEX2_1 | 169 | 171 | PF00082 | 0.313 |
| CLV_PCSK_KEX2_1 | 19 | 21 | PF00082 | 0.767 |
| CLV_PCSK_PC7_1 | 166 | 172 | PF00082 | 0.395 |
| CLV_PCSK_SKI1_1 | 108 | 112 | PF00082 | 0.346 |
| CLV_PCSK_SKI1_1 | 370 | 374 | PF00082 | 0.387 |
| CLV_PCSK_SKI1_1 | 9 | 13 | PF00082 | 0.755 |
| DEG_Nend_Nbox_1 | 1 | 3 | PF02207 | 0.604 |
| DOC_CKS1_1 | 192 | 197 | PF01111 | 0.328 |
| DOC_CYCLIN_yClb5_NLxxxL_5 | 292 | 300 | PF00134 | 0.277 |
| DOC_MAPK_gen_1 | 290 | 298 | PF00069 | 0.251 |
| DOC_MAPK_MEF2A_6 | 292 | 300 | PF00069 | 0.256 |
| DOC_MAPK_RevD_3 | 273 | 286 | PF00069 | 0.328 |
| DOC_PP2B_LxvP_1 | 179 | 182 | PF13499 | 0.268 |
| DOC_PP4_FxxP_1 | 192 | 195 | PF00568 | 0.267 |
| DOC_USP7_MATH_1 | 112 | 116 | PF00917 | 0.293 |
| DOC_USP7_MATH_1 | 23 | 27 | PF00917 | 0.599 |
| DOC_USP7_MATH_1 | 37 | 41 | PF00917 | 0.679 |
| DOC_USP7_MATH_1 | 48 | 52 | PF00917 | 0.556 |
| DOC_USP7_MATH_1 | 74 | 78 | PF00917 | 0.422 |
| DOC_USP7_UBL2_3 | 21 | 25 | PF12436 | 0.584 |
| DOC_USP7_UBL2_3 | 286 | 290 | PF12436 | 0.280 |
| DOC_WW_Pin1_4 | 101 | 106 | PF00397 | 0.431 |
| DOC_WW_Pin1_4 | 191 | 196 | PF00397 | 0.328 |
| DOC_WW_Pin1_4 | 248 | 253 | PF00397 | 0.301 |
| DOC_WW_Pin1_4 | 44 | 49 | PF00397 | 0.706 |
| LIG_14-3-3_CanoR_1 | 208 | 215 | PF00244 | 0.291 |
| LIG_14-3-3_CanoR_1 | 244 | 250 | PF00244 | 0.433 |
| LIG_14-3-3_CanoR_1 | 311 | 316 | PF00244 | 0.389 |
| LIG_Actin_WH2_2 | 297 | 313 | PF00022 | 0.395 |
| LIG_Actin_WH2_2 | 57 | 75 | PF00022 | 0.436 |
| LIG_AP2alpha_1 | 189 | 193 | PF02296 | 0.286 |
| LIG_BRCT_BRCA1_1 | 250 | 254 | PF00533 | 0.346 |
| LIG_CaM_IQ_9 | 197 | 212 | PF13499 | 0.256 |
| LIG_FHA_1 | 192 | 198 | PF00498 | 0.328 |
| LIG_FHA_1 | 233 | 239 | PF00498 | 0.387 |
| LIG_FHA_1 | 320 | 326 | PF00498 | 0.346 |
| LIG_FHA_1 | 347 | 353 | PF00498 | 0.328 |
| LIG_FHA_1 | 79 | 85 | PF00498 | 0.340 |
| LIG_FHA_2 | 321 | 327 | PF00498 | 0.286 |
| LIG_FHA_2 | 65 | 71 | PF00498 | 0.493 |
| LIG_GBD_Chelix_1 | 296 | 304 | PF00786 | 0.328 |
| LIG_LIR_Apic_2 | 190 | 195 | PF02991 | 0.252 |
| LIG_LIR_Gen_1 | 124 | 134 | PF02991 | 0.267 |
| LIG_LIR_Gen_1 | 184 | 193 | PF02991 | 0.306 |
| LIG_LIR_Gen_1 | 59 | 66 | PF02991 | 0.392 |
| LIG_LIR_Nem_3 | 107 | 113 | PF02991 | 0.266 |
| LIG_LIR_Nem_3 | 124 | 129 | PF02991 | 0.202 |
| LIG_LIR_Nem_3 | 184 | 189 | PF02991 | 0.291 |
| LIG_LIR_Nem_3 | 190 | 196 | PF02991 | 0.290 |
| LIG_LIR_Nem_3 | 237 | 243 | PF02991 | 0.267 |
| LIG_LIR_Nem_3 | 59 | 63 | PF02991 | 0.377 |
| LIG_PCNA_yPIPBox_3 | 306 | 319 | PF02747 | 0.328 |
| LIG_Pex14_1 | 188 | 192 | PF04695 | 0.395 |
| LIG_Pex14_2 | 189 | 193 | PF04695 | 0.252 |
| LIG_Pex14_2 | 250 | 254 | PF04695 | 0.346 |
| LIG_PTB_Apo_2 | 180 | 187 | PF02174 | 0.252 |
| LIG_PTB_Phospho_1 | 180 | 186 | PF10480 | 0.252 |
| LIG_RPA_C_Fungi | 88 | 100 | PF08784 | 0.312 |
| LIG_SH2_STAP1 | 113 | 117 | PF00017 | 0.252 |
| LIG_SH2_STAT5 | 113 | 116 | PF00017 | 0.252 |
| LIG_SH2_STAT5 | 128 | 131 | PF00017 | 0.397 |
| LIG_SH2_STAT5 | 186 | 189 | PF00017 | 0.267 |
| LIG_SH2_STAT5 | 264 | 267 | PF00017 | 0.262 |
| LIG_SH3_3 | 246 | 252 | PF00018 | 0.286 |
| LIG_SH3_3 | 271 | 277 | PF00018 | 0.267 |
| LIG_SH3_3 | 357 | 363 | PF00018 | 0.328 |
| LIG_SUMO_SIM_par_1 | 316 | 323 | PF11976 | 0.348 |
| LIG_TRAF2_1 | 199 | 202 | PF00917 | 0.256 |
| LIG_TRAF2_1 | 66 | 69 | PF00917 | 0.510 |
| LIG_UBA3_1 | 364 | 370 | PF00899 | 0.183 |
| MOD_CDK_SPxxK_3 | 101 | 108 | PF00069 | 0.328 |
| MOD_CK1_1 | 15 | 21 | PF00069 | 0.661 |
| MOD_CK1_1 | 24 | 30 | PF00069 | 0.778 |
| MOD_CK1_1 | 248 | 254 | PF00069 | 0.328 |
| MOD_CK1_1 | 78 | 84 | PF00069 | 0.399 |
| MOD_CK2_1 | 196 | 202 | PF00069 | 0.346 |
| MOD_CK2_1 | 320 | 326 | PF00069 | 0.312 |
| MOD_CK2_1 | 64 | 70 | PF00069 | 0.522 |
| MOD_GlcNHglycan | 14 | 17 | PF01048 | 0.742 |
| MOD_GlcNHglycan | 140 | 143 | PF01048 | 0.372 |
| MOD_GlcNHglycan | 21 | 24 | PF01048 | 0.746 |
| MOD_GlcNHglycan | 3 | 6 | PF01048 | 0.755 |
| MOD_GlcNHglycan | 33 | 38 | PF01048 | 0.697 |
| MOD_GlcNHglycan | 332 | 335 | PF01048 | 0.361 |
| MOD_GlcNHglycan | 39 | 42 | PF01048 | 0.650 |
| MOD_GSK3_1 | 112 | 119 | PF00069 | 0.273 |
| MOD_GSK3_1 | 15 | 22 | PF00069 | 0.746 |
| MOD_GSK3_1 | 204 | 211 | PF00069 | 0.301 |
| MOD_GSK3_1 | 230 | 237 | PF00069 | 0.334 |
| MOD_GSK3_1 | 248 | 255 | PF00069 | 0.158 |
| MOD_GSK3_1 | 33 | 40 | PF00069 | 0.622 |
| MOD_GSK3_1 | 44 | 51 | PF00069 | 0.587 |
| MOD_GSK3_1 | 64 | 71 | PF00069 | 0.425 |
| MOD_GSK3_1 | 74 | 81 | PF00069 | 0.403 |
| MOD_N-GLC_1 | 266 | 271 | PF02516 | 0.252 |
| MOD_N-GLC_1 | 311 | 316 | PF02516 | 0.328 |
| MOD_N-GLC_2 | 185 | 187 | PF02516 | 0.267 |
| MOD_NEK2_1 | 1 | 6 | PF00069 | 0.598 |
| MOD_NEK2_1 | 111 | 116 | PF00069 | 0.268 |
| MOD_NEK2_1 | 122 | 127 | PF00069 | 0.300 |
| MOD_NEK2_1 | 138 | 143 | PF00069 | 0.311 |
| MOD_NEK2_1 | 320 | 325 | PF00069 | 0.386 |
| MOD_NEK2_1 | 84 | 89 | PF00069 | 0.334 |
| MOD_PIKK_1 | 50 | 56 | PF00454 | 0.601 |
| MOD_PIKK_1 | 64 | 70 | PF00454 | 0.503 |
| MOD_PIKK_1 | 84 | 90 | PF00454 | 0.395 |
| MOD_PKA_1 | 12 | 18 | PF00069 | 0.723 |
| MOD_PKA_1 | 19 | 25 | PF00069 | 0.726 |
| MOD_PKA_2 | 122 | 128 | PF00069 | 0.259 |
| MOD_PKA_2 | 19 | 25 | PF00069 | 0.736 |
| MOD_PKA_2 | 204 | 210 | PF00069 | 0.252 |
| MOD_PKA_2 | 37 | 43 | PF00069 | 0.400 |
| MOD_Plk_1 | 311 | 317 | PF00069 | 0.328 |
| MOD_Plk_1 | 356 | 362 | PF00069 | 0.252 |
| MOD_Plk_1 | 68 | 74 | PF00069 | 0.546 |
| MOD_Plk_4 | 153 | 159 | PF00069 | 0.252 |
| MOD_Plk_4 | 234 | 240 | PF00069 | 0.252 |
| MOD_Plk_4 | 356 | 362 | PF00069 | 0.258 |
| MOD_Plk_4 | 59 | 65 | PF00069 | 0.521 |
| MOD_ProDKin_1 | 101 | 107 | PF00069 | 0.431 |
| MOD_ProDKin_1 | 191 | 197 | PF00069 | 0.328 |
| MOD_ProDKin_1 | 248 | 254 | PF00069 | 0.301 |
| MOD_ProDKin_1 | 44 | 50 | PF00069 | 0.705 |
| TRG_AP2beta_CARGO_1 | 124 | 133 | PF09066 | 0.286 |
| TRG_DiLeu_BaEn_2 | 105 | 111 | PF01217 | 0.328 |
| TRG_ENDOCYTIC_2 | 186 | 189 | PF00928 | 0.292 |
| TRG_ER_diArg_1 | 168 | 171 | PF00400 | 0.312 |
| TRG_ER_diArg_1 | 282 | 285 | PF00400 | 0.274 |
| TRG_ER_FFAT_2 | 190 | 198 | PF00635 | 0.207 |
| TRG_Pf-PMV_PEXEL_1 | 93 | 97 | PF00026 | 0.252 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P4N5 | Leptomonas seymouri | 80% | 100% |
| A0A0S4JCE9 | Bodo saltans | 51% | 100% |
| A0A0S4KFM4 | Bodo saltans | 27% | 97% |
| A0A1X0NWI9 | Trypanosomatidae | 60% | 100% |
| A0A3Q8IEQ5 | Leishmania donovani | 96% | 100% |
| A0A422NEH6 | Trypanosoma rangeli | 60% | 100% |
| A3MVC9 | Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1) | 30% | 100% |
| A4HYL6 | Leishmania infantum | 96% | 100% |
| A4YHK6 | Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) | 27% | 100% |
| A4ZZ93 | Leishmania donovani | 97% | 100% |
| A6URC0 | Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB) | 38% | 100% |
| A8AA61 | Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125) | 28% | 100% |
| A9KDQ8 | Coxiella burnetii (strain Dugway 5J108-111) | 22% | 100% |
| A9NCJ8 | Coxiella burnetii (strain RSA 331 / Henzerling II) | 22% | 100% |
| B0R5L2 | Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) | 31% | 100% |
| B2IZP9 | Nostoc punctiforme (strain ATCC 29133 / PCC 73102) | 24% | 97% |
| B2KER6 | Elusimicrobium minutum (strain Pei191) | 23% | 100% |
| B3QLU4 | Chlorobaculum parvum (strain DSM 263 / NCIMB 8327) | 26% | 100% |
| B6YVB1 | Thermococcus onnurineus (strain NA1) | 38% | 100% |
| B8HNE7 | Cyanothece sp. (strain PCC 7425 / ATCC 29141) | 22% | 95% |
| C3MPN8 | Sulfolobus islandicus (strain L.S.2.15 / Lassen #1) | 26% | 100% |
| C3MYN2 | Sulfolobus islandicus (strain M.14.25 / Kamchatka #1) | 26% | 100% |
| C3N5B4 | Sulfolobus islandicus (strain M.16.27) | 26% | 100% |
| C3NDW8 | Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1) | 26% | 100% |
| C3NHT5 | Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2) | 26% | 100% |
| C4KGY0 | Sulfolobus islandicus (strain M.16.4 / Kamchatka #3) | 26% | 100% |
| C5A5L0 | Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) | 39% | 100% |
| C9ZHW4 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 58% | 100% |
| E9AI79 | Leishmania braziliensis | 87% | 100% |
| E9AUG5 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 94% | 100% |
| O26230 | Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) | 24% | 100% |
| O27984 | Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) | 22% | 100% |
| O28088 | Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) | 24% | 100% |
| O50105 | Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) | 38% | 100% |
| O94337 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 37% | 100% |
| P38791 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 35% | 98% |
| P49365 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 37% | 100% |
| P49366 | Homo sapiens | 41% | 100% |
| P59650 | Coxiella burnetii (strain RSA 493 / Nine Mile phase I) | 22% | 100% |
| P60038 | Senecio vernalis | 37% | 100% |
| Q3TXU5 | Mus musculus | 41% | 100% |
| Q4GZD1 | Trypanosoma brucei brucei (strain 927/4 GUTat10.1) | 58% | 100% |
| Q4J978 | Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) | 26% | 100% |
| Q54MQ7 | Dictyostelium discoideum | 38% | 100% |
| Q58224 | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) | 39% | 100% |
| Q5JEY0 | Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) | 38% | 100% |
| Q6AY53 | Rattus norvegicus | 41% | 100% |
| Q6BJH5 | Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) | 35% | 100% |
| Q6CG56 | Yarrowia lipolytica (strain CLIB 122 / E 150) | 38% | 100% |
| Q6CNG7 | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) | 36% | 100% |
| Q6EWQ6 | Bos taurus | 41% | 100% |
| Q6FRN2 | Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) | 36% | 98% |
| Q6KZL5 | Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828) | 30% | 100% |
| Q6RJS2 | Brassica napus | 37% | 100% |
| Q75EW4 | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) | 35% | 99% |
| Q8DKP1 | Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1) | 23% | 95% |
| Q8KGF7 | Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) | 26% | 100% |
| Q8PV89 | Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) | 23% | 100% |
| Q8SQN2 | Encephalitozoon cuniculi (strain GB-M1) | 36% | 100% |
| Q8TS38 | Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) | 23% | 100% |
| Q8TXD7 | Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) | 25% | 100% |
| Q8U407 | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) | 39% | 100% |
| Q8YQL7 | Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) | 24% | 99% |
| Q8ZT09 | Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2) | 27% | 100% |
| Q971T3 | Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) | 26% | 100% |
| Q977X6 | Methanosarcina thermophila | 23% | 100% |
| Q97BN6 | Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1) | 29% | 100% |
| Q97ZF1 | Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) | 25% | 100% |
| Q9AXQ8 | Dianthus caryophyllus | 37% | 100% |
| Q9AXQ9 | Musa acuminata | 36% | 100% |
| Q9AXR0 | Solanum lycopersicum | 39% | 99% |
| Q9FI94 | Arabidopsis thaliana | 37% | 100% |
| Q9HL74 | Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) | 32% | 100% |
| Q9HPX2 | Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) | 31% | 100% |
| Q9M4B0 | Senecio vulgaris | 37% | 100% |
| Q9SC13 | Senecio vernalis | 37% | 100% |
| Q9SC14 | Senecio vernalis | 39% | 100% |
| Q9SC80 | Nicotiana tabacum | 38% | 100% |
| Q9V0N5 | Pyrococcus abyssi (strain GE5 / Orsay) | 37% | 100% |
| Q9VSF4 | Drosophila melanogaster | 39% | 100% |
| Q9XXJ0 | Caenorhabditis elegans | 40% | 100% |
| Q9YE72 | Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) | 28% | 100% |
| V5C0C4 | Trypanosoma cruzi | 61% | 100% |