LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Enkurin domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Enkurin domain-containing protein
Gene product:
Enkuring domain-containig protein
Species:
Leishmania major
UniProt:
Q4QD16_LEIMA
TriTrypDb:
LmjF.20.0270 * , LMJLV39_200007900 * , LMJSD75_200007800 *
Length:
367

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QD16
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QD16

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0005488 binding 1 2
GO:0005515 protein binding 2 2
GO:0005516 calmodulin binding 3 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 173 177 PF00656 0.669
CLV_NRD_NRD_1 115 117 PF00675 0.603
CLV_NRD_NRD_1 220 222 PF00675 0.508
CLV_NRD_NRD_1 230 232 PF00675 0.509
CLV_NRD_NRD_1 291 293 PF00675 0.346
CLV_NRD_NRD_1 312 314 PF00675 0.302
CLV_NRD_NRD_1 96 98 PF00675 0.625
CLV_PCSK_FUR_1 243 247 PF00082 0.420
CLV_PCSK_KEX2_1 219 221 PF00082 0.513
CLV_PCSK_KEX2_1 245 247 PF00082 0.409
CLV_PCSK_KEX2_1 290 292 PF00082 0.375
CLV_PCSK_KEX2_1 314 316 PF00082 0.294
CLV_PCSK_KEX2_1 9 11 PF00082 0.511
CLV_PCSK_PC1ET2_1 219 221 PF00082 0.532
CLV_PCSK_PC1ET2_1 245 247 PF00082 0.423
CLV_PCSK_PC1ET2_1 314 316 PF00082 0.337
CLV_PCSK_PC1ET2_1 9 11 PF00082 0.511
CLV_PCSK_SKI1_1 199 203 PF00082 0.571
CLV_PCSK_SKI1_1 335 339 PF00082 0.522
CLV_PCSK_SKI1_1 73 77 PF00082 0.503
DEG_Nend_UBRbox_1 1 4 PF02207 0.516
DOC_ANK_TNKS_1 77 84 PF00023 0.515
DOC_CYCLIN_RxL_1 6 16 PF00134 0.449
DOC_MAPK_gen_1 331 340 PF00069 0.280
DOC_MAPK_MEF2A_6 321 330 PF00069 0.307
DOC_PP1_RVXF_1 7 14 PF00149 0.455
DOC_USP7_MATH_1 239 243 PF00917 0.307
DOC_USP7_MATH_1 363 367 PF00917 0.567
DOC_USP7_UBL2_3 113 117 PF12436 0.428
DOC_USP7_UBL2_3 32 36 PF12436 0.704
DOC_USP7_UBL2_3 357 361 PF12436 0.531
DOC_USP7_UBL2_3 94 98 PF12436 0.662
DOC_WW_Pin1_4 121 126 PF00397 0.574
DOC_WW_Pin1_4 234 239 PF00397 0.307
DOC_WW_Pin1_4 36 41 PF00397 0.689
LIG_14-3-3_CanoR_1 231 235 PF00244 0.497
LIG_14-3-3_CanoR_1 313 323 PF00244 0.343
LIG_Actin_WH2_2 83 99 PF00022 0.518
LIG_APCC_ABBA_1 338 343 PF00400 0.383
LIG_BIR_III_4 145 149 PF00653 0.596
LIG_BRCT_BRCA1_1 122 126 PF00533 0.727
LIG_FHA_2 107 113 PF00498 0.462
LIG_FHA_2 315 321 PF00498 0.430
LIG_FHA_2 57 63 PF00498 0.565
LIG_LIR_Apic_2 112 118 PF02991 0.551
LIG_LIR_Gen_1 56 61 PF02991 0.589
LIG_LIR_Nem_3 18 24 PF02991 0.498
LIG_LIR_Nem_3 38 44 PF02991 0.374
LIG_LIR_Nem_3 56 60 PF02991 0.450
LIG_REV1ctd_RIR_1 72 82 PF16727 0.632
LIG_SH2_CRK 115 119 PF00017 0.641
LIG_SH2_CRK 41 45 PF00017 0.592
LIG_SH2_PTP2 273 276 PF00017 0.419
LIG_SH2_STAP1 24 28 PF00017 0.492
LIG_SH2_STAP1 45 49 PF00017 0.553
LIG_SH2_STAP1 57 61 PF00017 0.507
LIG_SH2_STAT3 298 301 PF00017 0.282
LIG_SH2_STAT5 273 276 PF00017 0.393
LIG_SH2_STAT5 41 44 PF00017 0.546
LIG_SH2_STAT5 95 98 PF00017 0.616
LIG_SH3_3 49 55 PF00018 0.606
LIG_SUMO_SIM_par_1 208 214 PF11976 0.522
LIG_TRAF2_1 109 112 PF00917 0.571
LIG_TRAF2_1 257 260 PF00917 0.371
LIG_TRAF2_1 278 281 PF00917 0.361
LIG_UBA3_1 20 26 PF00899 0.548
LIG_WRC_WIRS_1 57 62 PF05994 0.524
MOD_CK1_1 16 22 PF00069 0.522
MOD_CK1_1 230 236 PF00069 0.552
MOD_CK1_1 306 312 PF00069 0.370
MOD_CK1_1 39 45 PF00069 0.652
MOD_CK1_1 56 62 PF00069 0.655
MOD_CK2_1 106 112 PF00069 0.462
MOD_CK2_1 230 236 PF00069 0.552
MOD_CK2_1 24 30 PF00069 0.545
MOD_CK2_1 254 260 PF00069 0.381
MOD_CK2_1 314 320 PF00069 0.334
MOD_CK2_1 32 38 PF00069 0.508
MOD_CK2_1 56 62 PF00069 0.567
MOD_GlcNHglycan 131 134 PF01048 0.658
MOD_GlcNHglycan 136 139 PF01048 0.626
MOD_GlcNHglycan 15 18 PF01048 0.513
MOD_GlcNHglycan 165 170 PF01048 0.734
MOD_GlcNHglycan 172 175 PF01048 0.713
MOD_GlcNHglycan 183 186 PF01048 0.554
MOD_GlcNHglycan 26 29 PF01048 0.494
MOD_GSK3_1 120 127 PF00069 0.693
MOD_GSK3_1 195 202 PF00069 0.636
MOD_GSK3_1 226 233 PF00069 0.504
MOD_GSK3_1 32 39 PF00069 0.628
MOD_N-GLC_1 121 126 PF02516 0.723
MOD_N-GLC_1 154 159 PF02516 0.620
MOD_NEK2_1 205 210 PF00069 0.460
MOD_NEK2_1 254 259 PF00069 0.307
MOD_NEK2_1 285 290 PF00069 0.319
MOD_PIKK_1 124 130 PF00454 0.674
MOD_PKA_1 314 320 PF00069 0.334
MOD_PKA_2 230 236 PF00069 0.493
MOD_PKA_2 314 320 PF00069 0.334
MOD_Plk_1 319 325 PF00069 0.339
MOD_Plk_4 16 22 PF00069 0.522
MOD_Plk_4 56 62 PF00069 0.528
MOD_ProDKin_1 121 127 PF00069 0.578
MOD_ProDKin_1 234 240 PF00069 0.307
MOD_ProDKin_1 36 42 PF00069 0.690
MOD_SUMO_for_1 244 247 PF00179 0.292
MOD_SUMO_rev_2 247 254 PF00179 0.397
MOD_SUMO_rev_2 256 263 PF00179 0.373
MOD_SUMO_rev_2 27 34 PF00179 0.564
MOD_SUMO_rev_2 6 16 PF00179 0.424
TRG_DiLeu_BaEn_1 281 286 PF01217 0.312
TRG_DiLeu_BaEn_2 249 255 PF01217 0.307
TRG_ENDOCYTIC_2 273 276 PF00928 0.419
TRG_ENDOCYTIC_2 41 44 PF00928 0.690
TRG_ENDOCYTIC_2 57 60 PF00928 0.432
TRG_ER_diArg_1 289 292 PF00400 0.435
TRG_ER_diArg_1 312 315 PF00400 0.319
TRG_NLS_MonoCore_2 218 223 PF00514 0.526
TRG_NLS_MonoCore_2 312 317 PF00514 0.419
TRG_NLS_MonoExtC_3 312 318 PF00514 0.419
TRG_NLS_MonoExtN_4 218 223 PF00514 0.576
TRG_Pf-PMV_PEXEL_1 246 250 PF00026 0.402

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IJA5 Leptomonas seymouri 54% 100%
A0A1X0NWL2 Trypanosomatidae 39% 96%
A0A3R7MDK6 Trypanosoma rangeli 37% 93%
A0A3R7RTB5 Trypanosoma rangeli 26% 100%
A0A3S5H782 Leishmania donovani 92% 100%
A4HYL9 Leishmania infantum 92% 100%
C9ZHT3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 38% 98%
E9AI83 Leishmania braziliensis 76% 100%
E9AUG8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
V5DS69 Trypanosoma cruzi 39% 93%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS