Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QD10_LEIMA

TriTrypDb:

LmjF.20.0330 , LMJLV39_200008500 , LMJSD75_200008400

Length:

317

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QD10

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QD10

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	30	32	PF00675	0.545
CLV_NRD_NRD_1	314	316	PF00675	0.703
CLV_PCSK_KEX2_1	30	32	PF00082	0.545
CLV_PCSK_KEX2_1	314	316	PF00082	0.703
CLV_PCSK_SKI1_1	216	220	PF00082	0.545
CLV_PCSK_SKI1_1	236	240	PF00082	0.347
CLV_PCSK_SKI1_1	290	294	PF00082	0.662
CLV_PCSK_SKI1_1	30	34	PF00082	0.623
CLV_PCSK_SKI1_1	67	71	PF00082	0.778
DEG_Nend_Nbox_1	1	3	PF02207	0.604
DOC_CYCLIN_RxL_1	26	38	PF00134	0.622
DOC_MAPK_gen_1	213	223	PF00069	0.540
DOC_MAPK_gen_1	27	35	PF00069	0.528
DOC_MAPK_MEF2A_6	213	221	PF00069	0.565
DOC_PP2B_LxvP_1	219	222	PF13499	0.552
DOC_USP7_MATH_1	302	306	PF00917	0.632
DOC_USP7_MATH_1	60	64	PF00917	0.698
DOC_WW_Pin1_4	298	303	PF00397	0.613
DOC_WW_Pin1_4	309	314	PF00397	0.650
LIG_14-3-3_CanoR_1	290	299	PF00244	0.614
LIG_14-3-3_CanoR_1	84	88	PF00244	0.745
LIG_Actin_WH2_2	223	241	PF00022	0.414
LIG_FHA_1	230	236	PF00498	0.546
LIG_FHA_2	104	110	PF00498	0.773
LIG_FHA_2	118	124	PF00498	0.692
LIG_FHA_2	195	201	PF00498	0.570
LIG_Pex14_2	114	118	PF04695	0.792
LIG_SH2_CRK	262	266	PF00017	0.797
LIG_SH2_STAT5	43	46	PF00017	0.721
LIG_SH3_1	132	138	PF00018	0.804
LIG_SH3_1	75	81	PF00018	0.796
LIG_SH3_3	132	138	PF00018	0.752
LIG_SH3_3	190	196	PF00018	0.627
LIG_SH3_3	214	220	PF00018	0.569
LIG_SH3_3	75	81	PF00018	0.796
LIG_SUMO_SIM_par_1	31	38	PF11976	0.520
LIG_TRAF2_1	10	13	PF00917	0.554
LIG_UBA3_1	234	239	PF00899	0.425
LIG_WRC_WIRS_1	104	109	PF05994	0.659
LIG_WW_3	134	138	PF00397	0.723
MOD_CDC14_SPxK_1	312	315	PF00782	0.644
MOD_CDK_SPK_2	309	314	PF00069	0.674
MOD_CDK_SPxK_1	309	315	PF00069	0.632
MOD_CK1_1	301	307	PF00069	0.714
MOD_CK2_1	103	109	PF00069	0.768
MOD_CK2_1	194	200	PF00069	0.574
MOD_CK2_1	34	40	PF00069	0.631
MOD_GlcNHglycan	167	170	PF01048	0.772
MOD_GlcNHglycan	179	182	PF01048	0.582
MOD_GlcNHglycan	274	277	PF01048	0.642
MOD_GlcNHglycan	58	61	PF01048	0.788
MOD_GlcNHglycan	90	93	PF01048	0.710
MOD_GSK3_1	112	119	PF00069	0.650
MOD_GSK3_1	165	172	PF00069	0.830
MOD_GSK3_1	182	189	PF00069	0.677
MOD_GSK3_1	298	305	PF00069	0.728
MOD_GSK3_1	56	63	PF00069	0.762
MOD_GSK3_1	79	86	PF00069	0.596
MOD_N-GLC_1	169	174	PF02516	0.818
MOD_NEK2_1	151	156	PF00069	0.774
MOD_NEK2_1	165	170	PF00069	0.631
MOD_NEK2_1	238	243	PF00069	0.627
MOD_PKA_2	116	122	PF00069	0.724
MOD_PKA_2	156	162	PF00069	0.767
MOD_PKA_2	83	89	PF00069	0.598
MOD_Plk_1	302	308	PF00069	0.609
MOD_Plk_1	35	41	PF00069	0.538
MOD_Plk_2-3	194	200	PF00069	0.588
MOD_Plk_4	194	200	PF00069	0.588
MOD_Plk_4	83	89	PF00069	0.644
MOD_ProDKin_1	298	304	PF00069	0.615
MOD_ProDKin_1	309	315	PF00069	0.654
MOD_SUMO_rev_2	243	252	PF00179	0.554
TRG_DiLeu_BaLyEn_6	230	235	PF01217	0.532
TRG_ENDOCYTIC_2	262	265	PF00928	0.803
TRG_ER_diArg_1	131	134	PF00400	0.708
TRG_ER_diArg_1	230	233	PF00400	0.532
TRG_ER_diArg_1	30	32	PF00400	0.550
TRG_ER_diArg_1	313	315	PF00400	0.786
TRG_Pf-PMV_PEXEL_1	236	240	PF00026	0.424
TRG_Pf-PMV_PEXEL_1	31	36	PF00026	0.585

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P529	Leptomonas seymouri	42%	98%
A0A3S7WVT8	Leishmania donovani	90%	100%
A4HYR9	Leishmania infantum	90%	100%
E9AI89	Leishmania braziliensis	66%	98%
E9AUH4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%