MORN repeat family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

MORN repeat, putative

Species:

Leishmania major

UniProt:

Q4QCY2_LEIMA

TriTrypDb:

LmjF.20.0580 , LMJLV39_200011700 , LMJSD75_200011500

Length:

431

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005829	cytosol	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4QCY2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QCY2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	181	185	PF00656	0.328
CLV_C14_Caspase3-7	376	380	PF00656	0.723
CLV_C14_Caspase3-7	64	68	PF00656	0.634
CLV_NRD_NRD_1	328	330	PF00675	0.538
CLV_PCSK_KEX2_1	193	195	PF00082	0.305
CLV_PCSK_KEX2_1	209	211	PF00082	0.450
CLV_PCSK_KEX2_1	328	330	PF00082	0.538
CLV_PCSK_PC1ET2_1	193	195	PF00082	0.305
CLV_PCSK_PC1ET2_1	209	211	PF00082	0.450
CLV_PCSK_SKI1_1	305	309	PF00082	0.484
CLV_PCSK_SKI1_1	373	377	PF00082	0.566
CLV_PCSK_SKI1_1	56	60	PF00082	0.545
DEG_COP1_1	2	9	PF00400	0.639
DEG_SPOP_SBC_1	119	123	PF00917	0.656
DEG_SPOP_SBC_1	394	398	PF00917	0.704
DOC_MAPK_gen_1	209	219	PF00069	0.304
DOC_MAPK_gen_1	278	287	PF00069	0.300
DOC_MAPK_gen_1	328	335	PF00069	0.495
DOC_MAPK_JIP1_4	329	335	PF00069	0.504
DOC_MAPK_MEF2A_6	210	219	PF00069	0.304
DOC_MAPK_MEF2A_6	328	337	PF00069	0.502
DOC_PP1_RVXF_1	142	149	PF00149	0.437
DOC_PP2B_LxvP_1	285	288	PF13499	0.360
DOC_USP7_MATH_1	118	122	PF00917	0.752
DOC_USP7_MATH_1	345	349	PF00917	0.500
DOC_USP7_MATH_1	394	398	PF00917	0.654
DOC_USP7_MATH_1	40	44	PF00917	0.715
DOC_USP7_MATH_1	89	93	PF00917	0.618
DOC_WW_Pin1_4	113	118	PF00397	0.646
DOC_WW_Pin1_4	30	35	PF00397	0.719
LIG_14-3-3_CanoR_1	354	364	PF00244	0.418
LIG_Actin_WH2_2	150	166	PF00022	0.465
LIG_BIR_II_1	1	5	PF00653	0.640
LIG_DLG_GKlike_1	363	371	PF00625	0.545
LIG_FHA_1	141	147	PF00498	0.421
LIG_FHA_1	57	63	PF00498	0.612
LIG_FHA_1	67	73	PF00498	0.474
LIG_FHA_1	89	95	PF00498	0.615
LIG_FHA_2	257	263	PF00498	0.231
LIG_FHA_2	306	312	PF00498	0.494
LIG_FHA_2	356	362	PF00498	0.527
LIG_FHA_2	374	380	PF00498	0.617
LIG_FHA_2	396	402	PF00498	0.639
LIG_FHA_2	59	65	PF00498	0.603
LIG_LIR_Gen_1	238	247	PF02991	0.434
LIG_LIR_Nem_3	238	242	PF02991	0.477
LIG_LIR_Nem_3	301	307	PF02991	0.471
LIG_Pex14_2	270	274	PF04695	0.360
LIG_PTB_Apo_2	270	277	PF02174	0.255
LIG_PTB_Phospho_1	270	276	PF10480	0.255
LIG_REV1ctd_RIR_1	301	309	PF16727	0.474
LIG_RPA_C_Fungi	358	370	PF08784	0.510
LIG_SH2_CRK	239	243	PF00017	0.476
LIG_SH2_GRB2like	171	174	PF00017	0.415
LIG_SH2_SRC	286	289	PF00017	0.305
LIG_SH2_STAT3	153	156	PF00017	0.435
LIG_SH2_STAT3	247	250	PF00017	0.336
LIG_SH2_STAT5	153	156	PF00017	0.419
LIG_SH2_STAT5	178	181	PF00017	0.360
LIG_SH2_STAT5	216	219	PF00017	0.392
LIG_SH2_STAT5	247	250	PF00017	0.302
LIG_SH2_STAT5	286	289	PF00017	0.343
LIG_SH3_3	1	7	PF00018	0.637
LIG_SH3_3	31	37	PF00018	0.828
LIG_SH3_3	332	338	PF00018	0.650
LIG_SH3_4	232	239	PF00018	0.328
LIG_TRAF2_1	130	133	PF00917	0.573
MOD_CDK_SPxxK_3	113	120	PF00069	0.626
MOD_CK1_1	121	127	PF00069	0.736
MOD_CK1_1	331	337	PF00069	0.644
MOD_CK1_1	43	49	PF00069	0.734
MOD_CK2_1	127	133	PF00069	0.720
MOD_CK2_1	256	262	PF00069	0.231
MOD_CK2_1	305	311	PF00069	0.495
MOD_CK2_1	355	361	PF00069	0.543
MOD_Cter_Amidation	207	210	PF01082	0.360
MOD_Cter_Amidation	276	279	PF01082	0.327
MOD_GlcNHglycan	129	132	PF01048	0.695
MOD_GlcNHglycan	14	17	PF01048	0.681
MOD_GlcNHglycan	210	213	PF01048	0.369
MOD_GlcNHglycan	330	333	PF01048	0.611
MOD_GlcNHglycan	345	348	PF01048	0.729
MOD_GlcNHglycan	381	385	PF01048	0.764
MOD_GlcNHglycan	42	45	PF01048	0.707
MOD_GlcNHglycan	48	51	PF01048	0.676
MOD_GlcNHglycan	98	101	PF01048	0.667
MOD_GSK3_1	118	125	PF00069	0.696
MOD_GSK3_1	12	19	PF00069	0.712
MOD_GSK3_1	127	134	PF00069	0.619
MOD_GSK3_1	22	29	PF00069	0.630
MOD_GSK3_1	256	263	PF00069	0.231
MOD_GSK3_1	40	47	PF00069	0.837
MOD_GSK3_1	402	409	PF00069	0.774
MOD_GSK3_1	54	61	PF00069	0.597
MOD_GSK3_1	84	91	PF00069	0.672
MOD_NEK2_1	355	360	PF00069	0.579
MOD_NEK2_2	26	31	PF00069	0.560
MOD_PIKK_1	323	329	PF00454	0.675
MOD_PIKK_1	84	90	PF00454	0.602
MOD_PKA_1	328	334	PF00069	0.562
MOD_PKA_2	245	251	PF00069	0.347
MOD_PKA_2	260	266	PF00069	0.303
MOD_PKA_2	328	334	PF00069	0.633
MOD_Plk_1	26	32	PF00069	0.611
MOD_Plk_2-3	132	138	PF00069	0.630
MOD_ProDKin_1	113	119	PF00069	0.647
MOD_ProDKin_1	30	36	PF00069	0.718
MOD_SUMO_rev_2	136	146	PF00179	0.522
MOD_SUMO_rev_2	225	233	PF00179	0.328
MOD_SUMO_rev_2	49	58	PF00179	0.644
TRG_DiLeu_BaEn_1	142	147	PF01217	0.437
TRG_DiLeu_BaLyEn_6	68	73	PF01217	0.557
TRG_ENDOCYTIC_2	216	219	PF00928	0.390
TRG_ENDOCYTIC_2	224	227	PF00928	0.333
TRG_ENDOCYTIC_2	239	242	PF00928	0.465
TRG_ER_diArg_1	328	330	PF00400	0.538
TRG_ER_diArg_1	352	355	PF00400	0.438

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDL7	Leptomonas seymouri	60%	89%
A0A3Q8IAI5	Leishmania donovani	89%	100%
A4HYQ3	Leishmania infantum	88%	100%
E9AIB5	Leishmania braziliensis	63%	99%
E9AUK2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%
V5BGR9	Trypanosoma cruzi	27%	77%