Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QCT9_LEIMA

TriTrypDb:

LmjF.20.1070 , LMJLV39_200016300 , LMJSD75_200016100

Length:

291

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QCT9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QCT9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	113	115	PF00675	0.560
CLV_NRD_NRD_1	160	162	PF00675	0.679
CLV_NRD_NRD_1	183	185	PF00675	0.580
CLV_NRD_NRD_1	198	200	PF00675	0.593
CLV_NRD_NRD_1	207	209	PF00675	0.762
CLV_NRD_NRD_1	221	223	PF00675	0.626
CLV_NRD_NRD_1	226	228	PF00675	0.579
CLV_NRD_NRD_1	248	250	PF00675	0.622
CLV_NRD_NRD_1	287	289	PF00675	0.730
CLV_NRD_NRD_1	83	85	PF00675	0.539
CLV_NRD_NRD_1	97	99	PF00675	0.515
CLV_PCSK_KEX2_1	113	115	PF00082	0.560
CLV_PCSK_KEX2_1	158	160	PF00082	0.696
CLV_PCSK_KEX2_1	182	184	PF00082	0.591
CLV_PCSK_KEX2_1	207	209	PF00082	0.787
CLV_PCSK_KEX2_1	225	227	PF00082	0.596
CLV_PCSK_KEX2_1	241	243	PF00082	0.585
CLV_PCSK_KEX2_1	248	250	PF00082	0.619
CLV_PCSK_KEX2_1	277	279	PF00082	0.698
CLV_PCSK_KEX2_1	287	289	PF00082	0.709
CLV_PCSK_KEX2_1	83	85	PF00082	0.622
CLV_PCSK_KEX2_1	97	99	PF00082	0.558
CLV_PCSK_PC1ET2_1	158	160	PF00082	0.664
CLV_PCSK_PC1ET2_1	241	243	PF00082	0.543
CLV_PCSK_PC1ET2_1	277	279	PF00082	0.649
CLV_PCSK_PC1ET2_1	287	289	PF00082	0.590
CLV_PCSK_PC1ET2_1	83	85	PF00082	0.609
CLV_PCSK_PC7_1	222	228	PF00082	0.580
CLV_PCSK_PC7_1	79	85	PF00082	0.487
CLV_PCSK_SKI1_1	155	159	PF00082	0.665
CLV_PCSK_SKI1_1	161	165	PF00082	0.613
CLV_PCSK_SKI1_1	226	230	PF00082	0.596
CLV_PCSK_SKI1_1	234	238	PF00082	0.605
CLV_PCSK_SKI1_1	242	246	PF00082	0.530
CLV_PCSK_SKI1_1	84	88	PF00082	0.562
DEG_Nend_UBRbox_3	1	3	PF02207	0.636
DOC_CKS1_1	47	52	PF01111	0.585
DOC_MAPK_gen_1	207	216	PF00069	0.624
DOC_MAPK_gen_1	30	39	PF00069	0.559
DOC_MAPK_JIP1_4	208	214	PF00069	0.537
DOC_MAPK_MEF2A_6	207	216	PF00069	0.624
DOC_PP2B_LxvP_1	122	125	PF13499	0.630
DOC_PP4_FxxP_1	33	36	PF00568	0.586
DOC_USP7_MATH_1	106	110	PF00917	0.628
DOC_USP7_MATH_1	125	129	PF00917	0.645
DOC_USP7_MATH_1	174	178	PF00917	0.612
DOC_USP7_MATH_1	192	196	PF00917	0.664
DOC_USP7_MATH_1	218	222	PF00917	0.726
DOC_USP7_MATH_1	28	32	PF00917	0.592
DOC_USP7_UBL2_3	144	148	PF12436	0.674
DOC_USP7_UBL2_3	151	155	PF12436	0.608
DOC_USP7_UBL2_3	158	162	PF12436	0.539
DOC_USP7_UBL2_3	264	268	PF12436	0.593
DOC_USP7_UBL2_3	53	57	PF12436	0.556
DOC_USP7_UBL2_3	83	87	PF12436	0.508
DOC_WW_Pin1_4	15	20	PF00397	0.593
DOC_WW_Pin1_4	242	247	PF00397	0.562
DOC_WW_Pin1_4	46	51	PF00397	0.600
LIG_14-3-3_CanoR_1	142	148	PF00244	0.571
LIG_14-3-3_CanoR_1	161	169	PF00244	0.600
LIG_14-3-3_CanoR_1	176	180	PF00244	0.650
LIG_14-3-3_CanoR_1	225	233	PF00244	0.614
LIG_Actin_WH2_2	150	166	PF00022	0.599
LIG_BIR_III_2	25	29	PF00653	0.566
LIG_FHA_1	124	130	PF00498	0.714
LIG_FHA_1	88	94	PF00498	0.558
LIG_FHA_2	47	53	PF00498	0.664
LIG_LIR_Apic_2	31	36	PF02991	0.586
LIG_RPA_C_Fungi	74	86	PF08784	0.483
LIG_SH2_STAT5	21	24	PF00017	0.596
LIG_SH3_1	130	136	PF00018	0.654
LIG_SH3_3	130	136	PF00018	0.597
LIG_SH3_3	198	204	PF00018	0.672
LIG_SH3_3	241	247	PF00018	0.575
LIG_SH3_3	248	254	PF00018	0.612
LIG_SH3_3	255	261	PF00018	0.716
LIG_SUMO_SIM_par_1	120	126	PF11976	0.539
LIG_SUMO_SIM_par_1	41	49	PF11976	0.602
LIG_TRAF2_1	49	52	PF00917	0.586
LIG_TRAF2_1	6	9	PF00917	0.631
LIG_TRAF2_1	65	68	PF00917	0.382
LIG_WW_3	245	249	PF00397	0.528
MOD_CDK_SPxK_1	242	248	PF00069	0.534
MOD_CDK_SPxxK_3	242	249	PF00069	0.535
MOD_CDK_SPxxK_3	46	53	PF00069	0.586
MOD_CK1_1	123	129	PF00069	0.638
MOD_CK1_1	13	19	PF00069	0.511
MOD_CK1_1	146	152	PF00069	0.659
MOD_CK1_1	178	184	PF00069	0.678
MOD_CK1_1	263	269	PF00069	0.546
MOD_CK2_1	3	9	PF00069	0.547
MOD_CK2_1	38	44	PF00069	0.627
MOD_CK2_1	46	52	PF00069	0.575
MOD_Cter_Amidation	111	114	PF01082	0.572
MOD_Cter_Amidation	159	162	PF01082	0.626
MOD_Cter_Amidation	223	226	PF01082	0.576
MOD_DYRK1A_RPxSP_1	242	246	PF00069	0.537
MOD_GlcNHglycan	5	8	PF01048	0.555
MOD_GSK3_1	13	20	PF00069	0.568
MOD_GSK3_1	174	181	PF00069	0.647
MOD_GSK3_1	3	10	PF00069	0.517
MOD_NEK2_1	138	143	PF00069	0.627
MOD_NEK2_1	163	168	PF00069	0.601
MOD_NEK2_1	262	267	PF00069	0.563
MOD_NEK2_2	125	130	PF00069	0.613
MOD_NEK2_2	194	199	PF00069	0.600
MOD_PIKK_1	10	16	PF00454	0.566
MOD_PIKK_1	149	155	PF00454	0.519
MOD_PKA_1	226	232	PF00069	0.565
MOD_PKA_2	175	181	PF00069	0.599
MOD_PKA_2	185	191	PF00069	0.628
MOD_PKA_2	226	232	PF00069	0.680
MOD_PKB_1	225	233	PF00069	0.663
MOD_Plk_1	149	155	PF00069	0.519
MOD_Plk_1	58	64	PF00069	0.492
MOD_Plk_4	17	23	PF00069	0.658
MOD_Plk_4	175	181	PF00069	0.562
MOD_ProDKin_1	15	21	PF00069	0.596
MOD_ProDKin_1	242	248	PF00069	0.563
MOD_ProDKin_1	46	52	PF00069	0.597
MOD_SUMO_for_1	147	150	PF00179	0.649
TRG_ER_diArg_1	182	184	PF00400	0.587
TRG_ER_diArg_1	207	209	PF00400	0.797
TRG_ER_diArg_1	225	227	PF00400	0.647
TRG_ER_diArg_1	247	249	PF00400	0.549
TRG_ER_diArg_1	29	32	PF00400	0.560
TRG_ER_diArg_1	97	99	PF00400	0.640
TRG_ER_diLys_1	287	291	PF00400	0.560
TRG_NLS_Bipartite_1	207	226	PF00514	0.545
TRG_NLS_MonoExtC_3	157	162	PF00514	0.666
TRG_NLS_MonoExtC_3	221	226	PF00514	0.553
TRG_NLS_MonoExtC_3	82	87	PF00514	0.503
TRG_NLS_MonoExtN_4	155	162	PF00514	0.665
TRG_NLS_MonoExtN_4	275	280	PF00514	0.520
TRG_NLS_MonoExtN_4	83	88	PF00514	0.514
TRG_Pf-PMV_PEXEL_1	170	175	PF00026	0.783

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WW27	Leishmania donovani	79%	100%
A4HYU9	Leishmania infantum	80%	100%
E9AIF6	Leishmania braziliensis	54%	100%
E9AUP6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	75%	100%