Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QCT7_LEIMA

TriTrypDb:

LmjF.20.1090 , LMJLV39_200016500 , LMJSD75_200016300

Length:

1961

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0005654	nucleoplasm	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

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Expansion

Sequence features

Q4QCT7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0006508	proteolysis	4	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0008152	metabolic process	1	2
GO:0019538	protein metabolic process	3	2
GO:0043170	macromolecule metabolic process	3	2
GO:0044238	primary metabolic process	2	2
GO:0071704	organic substance metabolic process	2	2
GO:1901564	organonitrogen compound metabolic process	3	2

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Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	2
GO:0003677	DNA binding	4	2
GO:0003824	catalytic activity	1	2
GO:0005488	binding	1	2
GO:0008233	peptidase activity	3	2
GO:0008236	serine-type peptidase activity	4	2
GO:0016787	hydrolase activity	2	2
GO:0017171	serine hydrolase activity	3	2
GO:0097159	organic cyclic compound binding	2	2
GO:0140096	catalytic activity, acting on a protein	2	2

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1729	1733	PF00656	0.543
CLV_C14_Caspase3-7	1876	1880	PF00656	0.737
CLV_C14_Caspase3-7	1881	1885	PF00656	0.739
CLV_C14_Caspase3-7	782	786	PF00656	0.672
CLV_C14_Caspase3-7	861	865	PF00656	0.685
CLV_NRD_NRD_1	1024	1026	PF00675	0.545
CLV_NRD_NRD_1	1126	1128	PF00675	0.455
CLV_NRD_NRD_1	1475	1477	PF00675	0.494
CLV_NRD_NRD_1	1563	1565	PF00675	0.763
CLV_NRD_NRD_1	1598	1600	PF00675	0.543

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCX8	Leptomonas seymouri	40%	86%
A0A3Q8IA30	Leishmania donovani	88%	100%
A4HYV1	Leishmania infantum	90%	100%
E9AIF8	Leishmania braziliensis	69%	83%
E9AUP8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%

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