LeishMANIAdb
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Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Secreted protein
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania major
UniProt:
Q4QCQ7_LEIMA
TriTrypDb:
Length:
83

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QCQ7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QCQ7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 33 35 PF00675 0.413
CLV_PCSK_FUR_1 71 75 PF00082 0.464
CLV_PCSK_KEX2_1 73 75 PF00082 0.470
CLV_PCSK_PC1ET2_1 73 75 PF00082 0.470
CLV_PCSK_SKI1_1 65 69 PF00082 0.462
DEG_Nend_UBRbox_4 1 3 PF02207 0.410
DOC_MAPK_gen_1 34 43 PF00069 0.404
DOC_MAPK_gen_1 7 16 PF00069 0.398
DOC_MAPK_gen_1 71 81 PF00069 0.443
DOC_MAPK_MEF2A_6 37 45 PF00069 0.385
DOC_MAPK_MEF2A_6 74 83 PF00069 0.435
DOC_PP4_FxxP_1 10 13 PF00568 0.410
DOC_WW_Pin1_4 56 61 PF00397 0.398
LIG_14-3-3_CanoR_1 17 26 PF00244 0.398
LIG_14-3-3_CanoR_1 7 13 PF00244 0.404
LIG_14-3-3_CterR_2 80 83 PF00244 0.427
LIG_FHA_1 52 58 PF00498 0.377
LIG_FHA_2 17 23 PF00498 0.414
LIG_NRBOX 52 58 PF00104 0.377
LIG_PDZ_Class_2 78 83 PF00595 0.423
LIG_Pex14_1 6 10 PF04695 0.397
LIG_SH2_STAT5 15 18 PF00017 0.393
LIG_WW_3 68 72 PF00397 0.456
MOD_CK1_1 44 50 PF00069 0.365
MOD_CK1_1 52 58 PF00069 0.377
MOD_CK2_1 16 22 PF00069 0.405
MOD_CK2_1 56 62 PF00069 0.404
MOD_GlcNHglycan 10 13 PF01048 0.410
MOD_GSK3_1 52 59 PF00069 0.381
MOD_N-GLC_2 36 38 PF02516 0.412
MOD_NEK2_1 16 21 PF00069 0.401
MOD_NEK2_1 25 30 PF00069 0.397
MOD_NEK2_1 41 46 PF00069 0.366
MOD_PKA_2 16 22 PF00069 0.405
MOD_PKA_2 8 14 PF00069 0.405
MOD_Plk_4 52 58 PF00069 0.377
MOD_ProDKin_1 56 62 PF00069 0.404
TRG_ER_diArg_1 6 9 PF00400 0.398

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS