Separase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Separase

Gene product:

Peptidase C50 separase, putative

Species:

Leishmania major

UniProt:

Q4QCN4_LEIMA

TriTrypDb:

LmjF.20.1680 , LMJLV39_200022900 , LMJSD75_200022800

Length:

1279

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	8
GO:0005737	cytoplasm	2	2
GO:0005813	centrosome	3	2
GO:0005815	microtubule organizing center	2	2
GO:0005819	spindle	5	2
GO:0043226	organelle	2	8
GO:0043227	membrane-bounded organelle	3	8
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	8
GO:0043231	intracellular membrane-bounded organelle	4	8
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:0072686	mitotic spindle	6	2
GO:0110165	cellular anatomical entity	1	8

Expansion

Sequence features

Q4QCN4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QCN4

Function

Biological processes
Term	Name	Level	Count
GO:0006508	proteolysis	4	8
GO:0006807	nitrogen compound metabolic process	2	8
GO:0008152	metabolic process	1	8
GO:0009987	cellular process	1	8
GO:0019538	protein metabolic process	3	8
GO:0022402	cell cycle process	2	8
GO:0022414	reproductive process	1	2
GO:0043170	macromolecule metabolic process	3	8
GO:0044238	primary metabolic process	2	8
GO:0051304	chromosome separation	3	2
GO:0051307	meiotic chromosome separation	3	2
GO:0071704	organic substance metabolic process	2	8
GO:1901564	organonitrogen compound metabolic process	3	8
GO:1903046	meiotic cell cycle process	2	2
GO:0000280	nuclear division	6	6
GO:0006996	organelle organization	4	6
GO:0007059	chromosome segregation	2	6
GO:0016043	cellular component organization	3	6
GO:0048285	organelle fission	5	6
GO:0071840	cellular component organization or biogenesis	2	6
GO:0098813	nuclear chromosome segregation	3	6

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	8
GO:0004175	endopeptidase activity	4	8
GO:0004197	cysteine-type endopeptidase activity	5	8
GO:0008233	peptidase activity	3	8
GO:0008234	cysteine-type peptidase activity	4	8
GO:0016787	hydrolase activity	2	8
GO:0140096	catalytic activity, acting on a protein	2	8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1208	1212	PF00656	0.500
CLV_C14_Caspase3-7	196	200	PF00656	0.421
CLV_C14_Caspase3-7	234	238	PF00656	0.383
CLV_C14_Caspase3-7	609	613	PF00656	0.472
CLV_C14_Caspase3-7	614	618	PF00656	0.519
CLV_C14_Caspase3-7	619	623	PF00656	0.529
CLV_C14_Caspase3-7	791	795	PF00656	0.475
CLV_C14_Caspase3-7	822	826	PF00656	0.568
CLV_NRD_NRD_1	1004	1006	PF00675	0.493
CLV_NRD_NRD_1	1121	1123	PF00675	0.269
CLV_NRD_NRD_1	1245	1247	PF00675	0.414
CLV_NRD_NRD_1	182	184	PF00675	0.460
CLV_NRD_NRD_1	205	207	PF00675	0.544
CLV_NRD_NRD_1	218	220	PF00675	0.323
CLV_NRD_NRD_1	340	342	PF00675	0.510
CLV_NRD_NRD_1	433	435	PF00675	0.435
CLV_NRD_NRD_1	641	643	PF00675	0.482
CLV_NRD_NRD_1	698	700	PF00675	0.453
CLV_NRD_NRD_1	800	802	PF00675	0.438
CLV_PCSK_FUR_1	338	342	PF00082	0.486
CLV_PCSK_FUR_1	797	801	PF00082	0.486
CLV_PCSK_KEX2_1	1004	1006	PF00082	0.540
CLV_PCSK_KEX2_1	1121	1123	PF00082	0.283
CLV_PCSK_KEX2_1	1245	1247	PF00082	0.416
CLV_PCSK_KEX2_1	182	184	PF00082	0.460
CLV_PCSK_KEX2_1	205	207	PF00082	0.545
CLV_PCSK_KEX2_1	218	220	PF00082	0.321
CLV_PCSK_KEX2_1	340	342	PF00082	0.510
CLV_PCSK_KEX2_1	433	435	PF00082	0.435
CLV_PCSK_KEX2_1	698	700	PF00082	0.453
CLV_PCSK_KEX2_1	799	801	PF00082	0.557
CLV_PCSK_KEX2_1	917	919	PF00082	0.411
CLV_PCSK_PC1ET2_1	917	919	PF00082	0.417
CLV_PCSK_SKI1_1	1121	1125	PF00082	0.272
CLV_PCSK_SKI1_1	1151	1155	PF00082	0.304
CLV_PCSK_SKI1_1	206	210	PF00082	0.510
CLV_PCSK_SKI1_1	218	222	PF00082	0.345
CLV_PCSK_SKI1_1	341	345	PF00082	0.543
CLV_PCSK_SKI1_1	572	576	PF00082	0.447
CLV_PCSK_SKI1_1	605	609	PF00082	0.464
CLV_PCSK_SKI1_1	719	723	PF00082	0.349
CLV_PCSK_SKI1_1	770	774	PF00082	0.538
CLV_PCSK_SKI1_1	921	925	PF00082	0.509
CLV_Separin_Metazoa	331	335	PF03568	0.445
DEG_APCC_DBOX_1	920	928	PF00400	0.416
DEG_COP1_1	1040	1049	PF00400	0.483
DEG_MDM2_SWIB_1	288	296	PF02201	0.435
DEG_SPOP_SBC_1	576	580	PF00917	0.474
DEG_SPOP_SBC_1	774	778	PF00917	0.570
DOC_CDC14_PxL_1	880	888	PF14671	0.521
DOC_CKS1_1	396	401	PF01111	0.274
DOC_CKS1_1	664	669	PF01111	0.739
DOC_CYCLIN_RxL_1	1118	1128	PF00134	0.472
DOC_CYCLIN_RxL_1	216	226	PF00134	0.393
DOC_CYCLIN_RxL_1	917	928	PF00134	0.416
DOC_MAPK_gen_1	917	924	PF00069	0.376
DOC_MAPK_MEF2A_6	1016	1023	PF00069	0.534
DOC_MAPK_MEF2A_6	394	403	PF00069	0.431
DOC_MAPK_MEF2A_6	90	99	PF00069	0.472
DOC_PP1_RVXF_1	623	630	PF00149	0.540
DOC_PP2B_LxvP_1	1012	1015	PF13499	0.410
DOC_PP2B_LxvP_1	97	100	PF13499	0.619
DOC_PP2B_PxIxI_1	398	404	PF00149	0.398
DOC_PP4_FxxP_1	1188	1191	PF00568	0.504
DOC_PP4_FxxP_1	321	324	PF00568	0.400
DOC_SPAK_OSR1_1	544	548	PF12202	0.402
DOC_USP7_MATH_1	1197	1201	PF00917	0.500
DOC_USP7_MATH_1	138	142	PF00917	0.614
DOC_USP7_MATH_1	211	215	PF00917	0.448
DOC_USP7_MATH_1	242	246	PF00917	0.484
DOC_USP7_MATH_1	257	261	PF00917	0.505
DOC_USP7_MATH_1	343	347	PF00917	0.724
DOC_USP7_MATH_1	444	448	PF00917	0.636
DOC_USP7_MATH_1	451	455	PF00917	0.455
DOC_USP7_MATH_1	621	625	PF00917	0.594
DOC_USP7_MATH_1	630	634	PF00917	0.579
DOC_USP7_MATH_1	670	674	PF00917	0.452
DOC_USP7_MATH_1	684	688	PF00917	0.493
DOC_USP7_MATH_1	71	75	PF00917	0.535
DOC_USP7_MATH_1	723	727	PF00917	0.357
DOC_USP7_MATH_1	730	734	PF00917	0.391
DOC_USP7_MATH_1	774	778	PF00917	0.666
DOC_USP7_MATH_1	838	842	PF00917	0.496
DOC_USP7_MATH_1	941	945	PF00917	0.496
DOC_USP7_MATH_1	949	953	PF00917	0.527
DOC_USP7_MATH_1	966	970	PF00917	0.286
DOC_WW_Pin1_4	106	111	PF00397	0.615
DOC_WW_Pin1_4	1114	1119	PF00397	0.457
DOC_WW_Pin1_4	1161	1166	PF00397	0.472
DOC_WW_Pin1_4	309	314	PF00397	0.622
DOC_WW_Pin1_4	371	376	PF00397	0.347
DOC_WW_Pin1_4	395	400	PF00397	0.409
DOC_WW_Pin1_4	454	459	PF00397	0.440
DOC_WW_Pin1_4	65	70	PF00397	0.459
DOC_WW_Pin1_4	663	668	PF00397	0.752
DOC_WW_Pin1_4	74	79	PF00397	0.483
DOC_WW_Pin1_4	888	893	PF00397	0.637
DOC_WW_Pin1_4	987	992	PF00397	0.432
LIG_14-3-3_CanoR_1	1178	1188	PF00244	0.599
LIG_14-3-3_CanoR_1	149	159	PF00244	0.330
LIG_14-3-3_CanoR_1	182	189	PF00244	0.370
LIG_14-3-3_CanoR_1	205	209	PF00244	0.502
LIG_14-3-3_CanoR_1	40	45	PF00244	0.495
LIG_14-3-3_CanoR_1	475	485	PF00244	0.293
LIG_14-3-3_CanoR_1	544	550	PF00244	0.400
LIG_14-3-3_CanoR_1	572	577	PF00244	0.441
LIG_14-3-3_CanoR_1	631	639	PF00244	0.506
LIG_14-3-3_CanoR_1	698	707	PF00244	0.484
LIG_14-3-3_CanoR_1	719	727	PF00244	0.455
LIG_14-3-3_CanoR_1	818	824	PF00244	0.442
LIG_14-3-3_CanoR_1	861	869	PF00244	0.550
LIG_14-3-3_CanoR_1	894	903	PF00244	0.494
LIG_14-3-3_CanoR_1	904	913	PF00244	0.394
LIG_Actin_WH2_2	5	23	PF00022	0.427
LIG_APCC_ABBA_1	1067	1072	PF00400	0.483
LIG_APCC_ABBAyCdc20_2	1066	1072	PF00400	0.500
LIG_BIR_III_4	825	829	PF00653	0.439
LIG_BRCT_BRCA1_1	311	315	PF00533	0.514
LIG_CtBP_PxDLS_1	241	245	PF00389	0.488
LIG_deltaCOP1_diTrp_1	803	810	PF00928	0.462
LIG_DLG_GKlike_1	1045	1052	PF00625	0.483
LIG_FHA_1	1082	1088	PF00498	0.492
LIG_FHA_1	1114	1120	PF00498	0.472
LIG_FHA_1	1165	1171	PF00498	0.472
LIG_FHA_1	15	21	PF00498	0.422
LIG_FHA_1	151	157	PF00498	0.449
LIG_FHA_1	222	228	PF00498	0.403
LIG_FHA_1	396	402	PF00498	0.382
LIG_FHA_1	419	425	PF00498	0.348
LIG_FHA_1	509	515	PF00498	0.447
LIG_FHA_1	526	532	PF00498	0.494
LIG_FHA_1	577	583	PF00498	0.486
LIG_FHA_1	632	638	PF00498	0.636
LIG_FHA_1	674	680	PF00498	0.558
LIG_FHA_1	874	880	PF00498	0.420
LIG_FHA_1	94	100	PF00498	0.483
LIG_FHA_2	1208	1214	PF00498	0.457
LIG_FHA_2	1234	1240	PF00498	0.364
LIG_FHA_2	194	200	PF00498	0.377
LIG_FHA_2	232	238	PF00498	0.427
LIG_FHA_2	478	484	PF00498	0.415
LIG_FHA_2	485	491	PF00498	0.377
LIG_FHA_2	559	565	PF00498	0.418
LIG_FHA_2	604	610	PF00498	0.418
LIG_FHA_2	789	795	PF00498	0.487
LIG_FHA_2	9	15	PF00498	0.505
LIG_GBD_Chelix_1	401	409	PF00786	0.399
LIG_GBD_Chelix_1	569	577	PF00786	0.430
LIG_HCF-1_HBM_1	1017	1020	PF13415	0.500
LIG_LIR_Apic_2	1186	1191	PF02991	0.500
LIG_LIR_Apic_2	395	399	PF02991	0.347
LIG_LIR_Apic_2	46	51	PF02991	0.441
LIG_LIR_Apic_2	586	590	PF02991	0.544
LIG_LIR_Apic_2	897	903	PF02991	0.450
LIG_LIR_Gen_1	1017	1027	PF02991	0.457
LIG_LIR_Gen_1	1182	1193	PF02991	0.504
LIG_LIR_Gen_1	1218	1228	PF02991	0.434
LIG_LIR_Gen_1	263	273	PF02991	0.420
LIG_LIR_Gen_1	312	322	PF02991	0.492
LIG_LIR_Gen_1	958	966	PF02991	0.401
LIG_LIR_Nem_3	1017	1023	PF02991	0.457
LIG_LIR_Nem_3	1182	1188	PF02991	0.506
LIG_LIR_Nem_3	1218	1224	PF02991	0.431
LIG_LIR_Nem_3	1258	1263	PF02991	0.373
LIG_LIR_Nem_3	178	184	PF02991	0.397
LIG_LIR_Nem_3	187	192	PF02991	0.346
LIG_LIR_Nem_3	263	269	PF02991	0.369
LIG_LIR_Nem_3	312	318	PF02991	0.514
LIG_LIR_Nem_3	38	44	PF02991	0.550
LIG_LIR_Nem_3	404	410	PF02991	0.465
LIG_LIR_Nem_3	516	521	PF02991	0.550
LIG_LIR_Nem_3	958	964	PF02991	0.433
LIG_MYND_1	309	313	PF01753	0.482
LIG_MYND_3	1046	1050	PF01753	0.472
LIG_NRBOX	562	568	PF00104	0.397
LIG_PCNA_yPIPBox_3	259	272	PF02747	0.404
LIG_PCNA_yPIPBox_3	968	978	PF02747	0.433
LIG_Pex14_1	1093	1097	PF04695	0.500
LIG_Pex14_1	806	810	PF04695	0.444
LIG_Pex14_2	1188	1192	PF04695	0.488
LIG_Pex14_2	288	292	PF04695	0.433
LIG_Pex14_2	518	522	PF04695	0.431
LIG_PTB_Apo_2	980	987	PF02174	0.393
LIG_PTB_Phospho_1	980	986	PF10480	0.371
LIG_SH2_CRK	41	45	PF00017	0.516
LIG_SH2_NCK_1	587	591	PF00017	0.543
LIG_SH2_PTP2	396	399	PF00017	0.361
LIG_SH2_PTP2	546	549	PF00017	0.396
LIG_SH2_SRC	1137	1140	PF00017	0.435
LIG_SH2_SRC	682	685	PF00017	0.446
LIG_SH2_STAT5	1020	1023	PF00017	0.457
LIG_SH2_STAT5	1051	1054	PF00017	0.534
LIG_SH2_STAT5	1137	1140	PF00017	0.435
LIG_SH2_STAT5	1194	1197	PF00017	0.500
LIG_SH2_STAT5	1252	1255	PF00017	0.376
LIG_SH2_STAT5	1266	1269	PF00017	0.437
LIG_SH2_STAT5	396	399	PF00017	0.365
LIG_SH2_STAT5	467	470	PF00017	0.438
LIG_SH2_STAT5	546	549	PF00017	0.473
LIG_SH2_STAT5	682	685	PF00017	0.387
LIG_SH2_STAT5	885	888	PF00017	0.465
LIG_SH3_1	552	558	PF00018	0.387
LIG_SH3_3	1112	1118	PF00018	0.534
LIG_SH3_3	236	242	PF00018	0.404
LIG_SH3_3	380	386	PF00018	0.470
LIG_SH3_3	552	558	PF00018	0.402
LIG_SH3_3	624	630	PF00018	0.534
LIG_SH3_3	664	670	PF00018	0.567
LIG_SH3_3	92	98	PF00018	0.485
LIG_SUMO_SIM_anti_2	1010	1015	PF11976	0.488
LIG_SUMO_SIM_anti_2	112	118	PF11976	0.459
LIG_SUMO_SIM_anti_2	1167	1173	PF11976	0.483
LIG_SUMO_SIM_anti_2	231	237	PF11976	0.412
LIG_SUMO_SIM_anti_2	477	487	PF11976	0.418
LIG_SUMO_SIM_anti_2	561	567	PF11976	0.304
LIG_SUMO_SIM_anti_2	676	681	PF11976	0.361
LIG_SUMO_SIM_par_1	115	123	PF11976	0.500
LIG_SUMO_SIM_par_1	398	404	PF11976	0.415
LIG_TRAF2_1	707	710	PF00917	0.492
LIG_TYR_ITIM	160	165	PF00017	0.300
LIG_TYR_ITIM	39	44	PF00017	0.471
LIG_WRC_WIRS_1	645	650	PF05994	0.346
LIG_WW_3	891	895	PF00397	0.538
MOD_CDK_SPK_2	371	376	PF00069	0.334
MOD_CDK_SPK_2	454	459	PF00069	0.420
MOD_CDK_SPxK_1	888	894	PF00069	0.624
MOD_CDK_SPxxK_3	1114	1121	PF00069	0.328
MOD_CK1_1	1060	1066	PF00069	0.412
MOD_CK1_1	1081	1087	PF00069	0.360
MOD_CK1_1	109	115	PF00069	0.519
MOD_CK1_1	1113	1119	PF00069	0.289
MOD_CK1_1	1226	1232	PF00069	0.513
MOD_CK1_1	140	146	PF00069	0.506
MOD_CK1_1	177	183	PF00069	0.556
MOD_CK1_1	231	237	PF00069	0.413
MOD_CK1_1	245	251	PF00069	0.495
MOD_CK1_1	260	266	PF00069	0.464
MOD_CK1_1	346	352	PF00069	0.603
MOD_CK1_1	357	363	PF00069	0.447
MOD_CK1_1	371	377	PF00069	0.300
MOD_CK1_1	43	49	PF00069	0.350
MOD_CK1_1	454	460	PF00069	0.466
MOD_CK1_1	525	531	PF00069	0.481
MOD_CK1_1	673	679	PF00069	0.314
MOD_CK1_1	686	692	PF00069	0.397
MOD_CK1_1	74	80	PF00069	0.469
MOD_CK1_1	775	781	PF00069	0.558
MOD_CK1_1	944	950	PF00069	0.672
MOD_CK2_1	1122	1128	PF00069	0.344
MOD_CK2_1	115	121	PF00069	0.396
MOD_CK2_1	1233	1239	PF00069	0.433
MOD_CK2_1	325	331	PF00069	0.536
MOD_CK2_1	558	564	PF00069	0.354
MOD_CK2_1	603	609	PF00069	0.477
MOD_CK2_1	649	655	PF00069	0.496
MOD_CK2_1	684	690	PF00069	0.596
MOD_GlcNHglycan	1058	1062	PF01048	0.384
MOD_GlcNHglycan	1112	1115	PF01048	0.413
MOD_GlcNHglycan	1175	1178	PF01048	0.292
MOD_GlcNHglycan	1181	1184	PF01048	0.292
MOD_GlcNHglycan	1195	1198	PF01048	0.171
MOD_GlcNHglycan	184	187	PF01048	0.411
MOD_GlcNHglycan	230	233	PF01048	0.443
MOD_GlcNHglycan	259	262	PF01048	0.481
MOD_GlcNHglycan	288	291	PF01048	0.398
MOD_GlcNHglycan	346	349	PF01048	0.574
MOD_GlcNHglycan	359	362	PF01048	0.369
MOD_GlcNHglycan	447	450	PF01048	0.664
MOD_GlcNHglycan	524	527	PF01048	0.346
MOD_GlcNHglycan	55	58	PF01048	0.429
MOD_GlcNHglycan	582	585	PF01048	0.560
MOD_GlcNHglycan	661	664	PF01048	0.608
MOD_GlcNHglycan	702	705	PF01048	0.561
MOD_GlcNHglycan	754	757	PF01048	0.592
MOD_GlcNHglycan	777	780	PF01048	0.639
MOD_GSK3_1	1041	1048	PF00069	0.292
MOD_GSK3_1	105	112	PF00069	0.491
MOD_GSK3_1	1053	1060	PF00069	0.292
MOD_GSK3_1	1109	1116	PF00069	0.363
MOD_GSK3_1	1193	1200	PF00069	0.351
MOD_GSK3_1	1251	1258	PF00069	0.366
MOD_GSK3_1	150	157	PF00069	0.405
MOD_GSK3_1	240	247	PF00069	0.501
MOD_GSK3_1	251	258	PF00069	0.600
MOD_GSK3_1	286	293	PF00069	0.461
MOD_GSK3_1	309	316	PF00069	0.666
MOD_GSK3_1	343	350	PF00069	0.583
MOD_GSK3_1	40	47	PF00069	0.425
MOD_GSK3_1	53	60	PF00069	0.405
MOD_GSK3_1	572	579	PF00069	0.511
MOD_GSK3_1	61	68	PF00069	0.412
MOD_GSK3_1	659	666	PF00069	0.637
MOD_GSK3_1	719	726	PF00069	0.336
MOD_GSK3_1	770	777	PF00069	0.531
MOD_GSK3_1	935	942	PF00069	0.445
MOD_N-GLC_2	656	658	PF02516	0.516
MOD_NEK2_1	1	6	PF00069	0.455
MOD_NEK2_1	115	120	PF00069	0.462
MOD_NEK2_1	1172	1177	PF00069	0.292
MOD_NEK2_1	1179	1184	PF00069	0.292
MOD_NEK2_1	244	249	PF00069	0.567
MOD_NEK2_1	325	330	PF00069	0.531
MOD_NEK2_1	344	349	PF00069	0.419
MOD_NEK2_1	368	373	PF00069	0.320
MOD_NEK2_1	392	397	PF00069	0.304
MOD_NEK2_1	514	519	PF00069	0.428
MOD_NEK2_1	522	527	PF00069	0.380
MOD_NEK2_1	53	58	PF00069	0.393
MOD_NEK2_1	545	550	PF00069	0.400
MOD_NEK2_1	577	582	PF00069	0.581
MOD_NEK2_1	697	702	PF00069	0.401
MOD_NEK2_1	750	755	PF00069	0.476
MOD_NEK2_1	763	768	PF00069	0.589
MOD_NEK2_1	772	777	PF00069	0.557
MOD_NEK2_1	8	13	PF00069	0.412
MOD_NEK2_2	1255	1260	PF00069	0.407
MOD_NEK2_2	912	917	PF00069	0.363
MOD_PIKK_1	1	7	PF00454	0.477
MOD_PIKK_1	1223	1229	PF00454	0.466
MOD_PIKK_1	347	353	PF00454	0.546
MOD_PIKK_1	426	432	PF00454	0.334
MOD_PIKK_1	558	564	PF00454	0.420
MOD_PIKK_1	57	63	PF00454	0.450
MOD_PIKK_1	684	690	PF00454	0.624
MOD_PIKK_1	763	769	PF00454	0.606
MOD_PKA_1	182	188	PF00069	0.434
MOD_PKA_2	1215	1221	PF00069	0.339
MOD_PKA_2	148	154	PF00069	0.431
MOD_PKA_2	182	188	PF00069	0.370
MOD_PKA_2	204	210	PF00069	0.329
MOD_PKA_2	426	432	PF00069	0.399
MOD_PKA_2	474	480	PF00069	0.307
MOD_PKA_2	630	636	PF00069	0.462
MOD_PKA_2	697	703	PF00069	0.411
MOD_PKA_2	723	729	PF00069	0.309
MOD_PKA_2	750	756	PF00069	0.438
MOD_PKB_1	717	725	PF00069	0.367
MOD_PKB_1	859	867	PF00069	0.427
MOD_Plk_1	1039	1045	PF00069	0.435
MOD_Plk_1	1057	1063	PF00069	0.171
MOD_Plk_1	177	183	PF00069	0.432
MOD_Plk_1	325	331	PF00069	0.595
MOD_Plk_1	942	948	PF00069	0.533
MOD_Plk_1	966	972	PF00069	0.401
MOD_Plk_2-3	1233	1239	PF00069	0.395
MOD_Plk_2-3	130	136	PF00069	0.464
MOD_Plk_4	1133	1139	PF00069	0.340
MOD_Plk_4	1164	1170	PF00069	0.308
MOD_Plk_4	1255	1261	PF00069	0.362
MOD_Plk_4	155	161	PF00069	0.352
MOD_Plk_4	184	190	PF00069	0.369
MOD_Plk_4	212	218	PF00069	0.388
MOD_Plk_4	231	237	PF00069	0.539
MOD_Plk_4	545	551	PF00069	0.533
MOD_Plk_4	572	578	PF00069	0.503
MOD_Plk_4	589	595	PF00069	0.472
MOD_Plk_4	673	679	PF00069	0.504
MOD_ProDKin_1	106	112	PF00069	0.613
MOD_ProDKin_1	1114	1120	PF00069	0.292
MOD_ProDKin_1	1161	1167	PF00069	0.313
MOD_ProDKin_1	309	315	PF00069	0.614
MOD_ProDKin_1	371	377	PF00069	0.342
MOD_ProDKin_1	395	401	PF00069	0.404
MOD_ProDKin_1	454	460	PF00069	0.444
MOD_ProDKin_1	65	71	PF00069	0.463
MOD_ProDKin_1	663	669	PF00069	0.746
MOD_ProDKin_1	74	80	PF00069	0.478
MOD_ProDKin_1	888	894	PF00069	0.651
MOD_ProDKin_1	987	993	PF00069	0.447
MOD_SUMO_rev_2	1272	1278	PF00179	0.461
TRG_DiLeu_BaEn_1	1017	1022	PF01217	0.328
TRG_DiLeu_BaEn_1	412	417	PF01217	0.395
TRG_DiLeu_BaEn_1	690	695	PF01217	0.466
TRG_DiLeu_BaEn_2	758	764	PF01217	0.507
TRG_DiLeu_BaLyEn_6	1119	1124	PF01217	0.301
TRG_DiLeu_BaLyEn_6	306	311	PF01217	0.450
TRG_DiLeu_BaLyEn_6	363	368	PF01217	0.416
TRG_DiLeu_BaLyEn_6	396	401	PF01217	0.548
TRG_DiLeu_BaLyEn_6	526	531	PF01217	0.513
TRG_DiLeu_BaLyEn_6	549	554	PF01217	0.451
TRG_ENDOCYTIC_2	1020	1023	PF00928	0.292
TRG_ENDOCYTIC_2	1155	1158	PF00928	0.343
TRG_ENDOCYTIC_2	1185	1188	PF00928	0.308
TRG_ENDOCYTIC_2	162	165	PF00928	0.387
TRG_ENDOCYTIC_2	41	44	PF00928	0.506
TRG_ENDOCYTIC_2	546	549	PF00928	0.390
TRG_ENDOCYTIC_2	986	989	PF00928	0.454
TRG_ER_diArg_1	1120	1122	PF00400	0.328
TRG_ER_diArg_1	181	183	PF00400	0.461
TRG_ER_diArg_1	204	206	PF00400	0.546
TRG_ER_diArg_1	217	219	PF00400	0.319
TRG_ER_diArg_1	281	284	PF00400	0.408
TRG_ER_diArg_1	338	341	PF00400	0.490
TRG_ER_diArg_1	433	435	PF00400	0.535
TRG_ER_diArg_1	502	505	PF00400	0.514
TRG_ER_diArg_1	697	699	PF00400	0.442
TRG_ER_diArg_1	797	800	PF00400	0.488
TRG_ER_diArg_1	858	861	PF00400	0.408
TRG_NES_CRM1_1	226	237	PF08389	0.286
TRG_Pf-PMV_PEXEL_1	10	14	PF00026	0.431
TRG_Pf-PMV_PEXEL_1	762	767	PF00026	0.653
TRG_Pf-PMV_PEXEL_1	921	925	PF00026	0.427

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCC3	Leptomonas seymouri	40%	98%
A0A3Q8IDS1	Leishmania donovani	91%	100%
A4HYZ7	Leishmania infantum	91%	100%
C9ZIN0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
E9AIL6	Leishmania braziliensis	74%	100%
E9AUU9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%