Glutaredoxin domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QCH0_LEIMA

TriTrypDb:

LmjF.21.0450 , LMJLV39_210009800 , LMJSD75_210009900

Length:

258

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QCH0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QCH0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	167	171	PF00656	0.689
CLV_C14_Caspase3-7	173	177	PF00656	0.592
CLV_MEL_PAP_1	84	90	PF00089	0.691
CLV_NRD_NRD_1	125	127	PF00675	0.623
CLV_NRD_NRD_1	210	212	PF00675	0.577
CLV_NRD_NRD_1	59	61	PF00675	0.666
CLV_NRD_NRD_1	98	100	PF00675	0.613
CLV_PCSK_KEX2_1	125	127	PF00082	0.623
CLV_PCSK_KEX2_1	209	211	PF00082	0.575
CLV_PCSK_KEX2_1	59	61	PF00082	0.666
CLV_PCSK_KEX2_1	98	100	PF00082	0.613
CLV_PCSK_SKI1_1	126	130	PF00082	0.526
CLV_PCSK_SKI1_1	2	6	PF00082	0.589
DEG_APCC_DBOX_1	26	34	PF00400	0.510
DEG_Nend_UBRbox_1	1	4	PF02207	0.599
DOC_CYCLIN_RxL_1	123	132	PF00134	0.522
DOC_CYCLIN_RxL_1	177	188	PF00134	0.702
DOC_MAPK_gen_1	209	216	PF00069	0.658
DOC_MAPK_gen_1	59	68	PF00069	0.686
DOC_PP2B_LxvP_1	182	185	PF13499	0.700
DOC_USP7_MATH_1	164	168	PF00917	0.661
DOC_USP7_MATH_1	91	95	PF00917	0.581
LIG_14-3-3_CanoR_1	211	217	PF00244	0.599
LIG_14-3-3_CanoR_1	27	31	PF00244	0.512
LIG_14-3-3_CanoR_1	93	97	PF00244	0.729
LIG_Actin_WH2_2	47	64	PF00022	0.660
LIG_Clathr_ClatBox_1	21	25	PF01394	0.558
LIG_FHA_1	16	22	PF00498	0.500
LIG_FHA_1	177	183	PF00498	0.706
LIG_FHA_2	243	249	PF00498	0.591
LIG_GBD_Chelix_1	142	150	PF00786	0.651
LIG_Integrin_isoDGR_2	222	224	PF01839	0.639
LIG_LIR_Gen_1	18	26	PF02991	0.549
LIG_LIR_Nem_3	18	22	PF02991	0.546
LIG_SH2_PTP2	111	114	PF00017	0.708
LIG_SH2_STAT5	101	104	PF00017	0.703
LIG_SH2_STAT5	111	114	PF00017	0.574
LIG_SH2_STAT5	192	195	PF00017	0.544
LIG_SH3_3	63	69	PF00018	0.584
LIG_TRAF2_1	245	248	PF00917	0.596
MOD_CK1_1	132	138	PF00069	0.539
MOD_CK1_1	83	89	PF00069	0.725
MOD_CK1_1	92	98	PF00069	0.621
MOD_CK2_1	242	248	PF00069	0.599
MOD_GlcNHglycan	131	134	PF01048	0.502
MOD_GlcNHglycan	166	169	PF01048	0.587
MOD_GlcNHglycan	195	198	PF01048	0.726
MOD_GlcNHglycan	219	222	PF01048	0.723
MOD_GSK3_1	172	179	PF00069	0.632
MOD_GSK3_1	188	195	PF00069	0.475
MOD_GSK3_1	79	86	PF00069	0.675
MOD_NEK2_1	129	134	PF00069	0.691
MOD_NEK2_1	193	198	PF00069	0.577
MOD_NEK2_1	80	85	PF00069	0.539
MOD_NEK2_2	39	44	PF00069	0.678
MOD_PKA_2	26	32	PF00069	0.510
MOD_PKA_2	92	98	PF00069	0.682
MOD_Plk_1	37	43	PF00069	0.559
MOD_Plk_2-3	170	176	PF00069	0.654
MOD_Plk_4	188	194	PF00069	0.534
MOD_Plk_4	212	218	PF00069	0.591
MOD_Plk_4	80	86	PF00069	0.702
TRG_DiLeu_BaEn_1	152	157	PF01217	0.651
TRG_DiLeu_BaLyEn_6	146	151	PF01217	0.646
TRG_ER_diArg_1	125	127	PF00400	0.644
TRG_ER_diArg_1	209	211	PF00400	0.575
TRG_ER_diArg_1	59	62	PF00400	0.668
TRG_NES_CRM1_1	25	38	PF08389	0.528
TRG_Pf-PMV_PEXEL_1	149	153	PF00026	0.534

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PE19	Leptomonas seymouri	43%	100%
A0A3Q8IBT2	Leishmania donovani	88%	100%
A4HZ44	Leishmania infantum	88%	100%
E9AV12	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%