Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania major

UniProt:

Q4QCB7_LEIMA

TriTrypDb:

LmjF.21.0870 , LMJLV39_210015700 , LMJSD75_210015800

Length:

913

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QCB7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QCB7

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	202	206	PF00656	0.778
CLV_C14_Caspase3-7	260	264	PF00656	0.737
CLV_C14_Caspase3-7	694	698	PF00656	0.828
CLV_NRD_NRD_1	123	125	PF00675	0.827
CLV_NRD_NRD_1	333	335	PF00675	0.606
CLV_NRD_NRD_1	829	831	PF00675	0.769
CLV_PCSK_KEX2_1	123	125	PF00082	0.710
CLV_PCSK_KEX2_1	410	412	PF00082	0.610
CLV_PCSK_KEX2_1	829	831	PF00082	0.767
CLV_PCSK_PC1ET2_1	410	412	PF00082	0.610

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IC08	Leishmania donovani	87%	100%
A4HBU2	Leishmania braziliensis	54%	100%
E9AGU8	Leishmania infantum	87%	100%
E9AV64	Leishmania mexicana (strain MHOM/GT/2001/U1103)	75%	100%

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