Putative 60S ribosomal protein L9

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

60S ribosomal protein L9, putative

Species:

Leishmania major

UniProt:

Q4QC91_LEIMA

TriTrypDb:

LmjF.21.1050 , LMJLV39_300042200 , LMJSD75_210018400

Length:

190

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 40

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	yes	yes: 7

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 28

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 14
NetGPI	no	yes: 0, no: 14

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	2
GO:0005737	cytoplasm	2	2
GO:0015934	large ribosomal subunit	4	3
GO:0022625	cytosolic large ribosomal subunit	5	3
GO:0032991	protein-containing complex	1	15
GO:0043226	organelle	2	14
GO:0043228	non-membrane-bounded organelle	3	14
GO:0043229	intracellular organelle	3	14
GO:0043232	intracellular non-membrane-bounded organelle	4	14
GO:0044391	ribosomal subunit	3	3
GO:0110165	cellular anatomical entity	1	14
GO:1990904	ribonucleoprotein complex	2	15
GO:0005840	ribosome	5	12

Expansion

Sequence features

Q4QC91

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QC91

PDB structure(s): 6az3_E

Function

Biological processes
Term	Name	Level	Count
GO:0002181	cytoplasmic translation	5	3
GO:0006412	translation	4	15
GO:0006518	peptide metabolic process	4	15
GO:0006807	nitrogen compound metabolic process	2	15
GO:0008152	metabolic process	1	15
GO:0009058	biosynthetic process	2	15
GO:0009059	macromolecule biosynthetic process	4	15
GO:0009987	cellular process	1	15
GO:0019538	protein metabolic process	3	15
GO:0034641	cellular nitrogen compound metabolic process	3	15
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	15
GO:0043043	peptide biosynthetic process	5	15
GO:0043170	macromolecule metabolic process	3	15
GO:0043603	amide metabolic process	3	15
GO:0043604	amide biosynthetic process	4	15
GO:0044237	cellular metabolic process	2	15
GO:0044238	primary metabolic process	2	15
GO:0044249	cellular biosynthetic process	3	15
GO:0044260	obsolete cellular macromolecule metabolic process	3	15
GO:0044271	cellular nitrogen compound biosynthetic process	4	15
GO:0071704	organic substance metabolic process	2	15
GO:1901564	organonitrogen compound metabolic process	3	15
GO:1901566	organonitrogen compound biosynthetic process	4	15
GO:1901576	organic substance biosynthetic process	3	15

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	15
GO:0003723	RNA binding	4	15
GO:0003735	structural constituent of ribosome	2	15
GO:0005198	structural molecule activity	1	15
GO:0005488	binding	1	15
GO:0019843	rRNA binding	5	15
GO:0097159	organic cyclic compound binding	2	15
GO:1901363	heterocyclic compound binding	2	15

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	121	123	PF00675	0.323
CLV_NRD_NRD_1	171	173	PF00675	0.350
CLV_NRD_NRD_1	22	24	PF00675	0.432
CLV_PCSK_FUR_1	119	123	PF00082	0.328
CLV_PCSK_KEX2_1	118	120	PF00082	0.328
CLV_PCSK_KEX2_1	121	123	PF00082	0.328
CLV_PCSK_KEX2_1	30	32	PF00082	0.369
CLV_PCSK_PC1ET2_1	118	120	PF00082	0.328
CLV_PCSK_PC1ET2_1	30	32	PF00082	0.369
CLV_PCSK_SKI1_1	112	116	PF00082	0.328
CLV_PCSK_SKI1_1	172	176	PF00082	0.342
CLV_PCSK_SKI1_1	23	27	PF00082	0.340
CLV_PCSK_SKI1_1	36	40	PF00082	0.333
CLV_PCSK_SKI1_1	52	56	PF00082	0.273
DEG_APCC_DBOX_1	171	179	PF00400	0.553
DOC_MAPK_gen_1	138	145	PF00069	0.604
DOC_MAPK_gen_1	172	180	PF00069	0.542
DOC_MAPK_gen_1	3	12	PF00069	0.488
DOC_MAPK_MEF2A_6	36	45	PF00069	0.540
DOC_MAPK_RevD_3	16	31	PF00069	0.569
DOC_PP2B_LxvP_1	10	13	PF13499	0.590
DOC_SPAK_OSR1_1	88	92	PF12202	0.448
DOC_USP7_UBL2_3	169	173	PF12436	0.553
LIG_14-3-3_CanoR_1	23	28	PF00244	0.571
LIG_14-3-3_CanoR_1	52	57	PF00244	0.528
LIG_CaM_IQ_9	38	54	PF13499	0.540
LIG_FHA_1	126	132	PF00498	0.519
LIG_FHA_1	15	21	PF00498	0.569
LIG_FHA_1	33	39	PF00498	0.442
LIG_FHA_1	51	57	PF00498	0.553
LIG_FHA_1	7	13	PF00498	0.550
LIG_FHA_2	182	188	PF00498	0.551
LIG_LIR_Gen_1	53	60	PF02991	0.540
LIG_LIR_Nem_3	53	57	PF02991	0.540
LIG_PCNA_yPIPBox_3	108	122	PF02747	0.632
LIG_SH2_STAT5	179	182	PF00017	0.503
LIG_SxIP_EBH_1	58	70	PF03271	0.632
MOD_CK1_1	6	12	PF00069	0.566
MOD_CK2_1	181	187	PF00069	0.538
MOD_Cter_Amidation	21	24	PF01082	0.391
MOD_Cter_Amidation	28	31	PF01082	0.345
MOD_GSK3_1	125	132	PF00069	0.621
MOD_GSK3_1	32	39	PF00069	0.622
MOD_N-GLC_1	100	105	PF02516	0.415
MOD_N-GLC_1	50	55	PF02516	0.391
MOD_N-GLC_1	69	74	PF02516	0.216
MOD_NEK2_1	69	74	PF00069	0.624
MOD_PIKK_1	129	135	PF00454	0.632
MOD_PKA_1	23	29	PF00069	0.591
MOD_PKA_1	30	36	PF00069	0.545
MOD_PKA_2	30	36	PF00069	0.540
MOD_Plk_1	100	106	PF00069	0.615
MOD_Plk_1	36	42	PF00069	0.632
MOD_Plk_1	50	56	PF00069	0.517
MOD_Plk_2-3	14	20	PF00069	0.573
MOD_SUMO_for_1	139	142	PF00179	0.528
TRG_DiLeu_BaEn_2	109	115	PF01217	0.528
TRG_ENDOCYTIC_2	95	98	PF00928	0.484
TRG_ER_diArg_1	119	122	PF00400	0.528
TRG_NES_CRM1_1	37	48	PF08389	0.632

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4KHJ4	Bodo saltans	65%	100%
A0A1X0NZC1	Trypanosomatidae	70%	100%
A0A3R7MU98	Trypanosoma rangeli	67%	100%
A0A3S7WWL2	Leishmania donovani	98%	100%
A0A3S7X3V0	Leishmania donovani	98%	100%
A0A422NWE3	Trypanosoma rangeli	67%	100%
A0A422P0X9	Trypanosoma rangeli	73%	100%
A0B9V4	Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)	38%	100%
A2BMD5	Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)	41%	100%
A3DNC3	Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)	39%	100%
A4FWA5	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	37%	100%
A4HBW5	Leishmania braziliensis	91%	100%
A4I672	Leishmania infantum	98%	100%
A5UL72	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	37%	100%
A6UQ60	Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)	35%	100%
A6UWV4	Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)	33%	100%
A6VH01	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	37%	100%
A8AC04	Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)	38%	100%
A9A9P8	Methanococcus maripaludis (strain C6 / ATCC BAA-1332)	35%	100%
B3PK52	Cellvibrio japonicus (strain Ueda107)	28%	100%
B6YSN0	Thermococcus onnurineus (strain NA1)	37%	100%
B8D5V4	Desulfurococcus amylolyticus (strain DSM 18924 / JCM 16383 / VKM B-2413 / 1221n)	38%	100%
C5A269	Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)	38%	100%
C9ZRE3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	72%	100%
E9AGX3	Leishmania infantum	98%	100%
E9AV89	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
O05637	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	34%	100%
O26127	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	35%	100%
O28370	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	34%	97%
O59433	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	37%	100%
O74905	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	50%	100%
P05738	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	51%	99%
P14030	Methanococcus vannielii	35%	100%
P14135	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	33%	100%
P17077	Rattus norvegicus	47%	99%
P30707	Pisum sativum	48%	98%
P32969	Homo sapiens	48%	99%
P49209	Arabidopsis thaliana	48%	98%
P49210	Oryza sativa subsp. japonica	54%	100%
P50882	Drosophila melanogaster	47%	100%
P51401	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	52%	99%
P51410	Mus musculus	47%	99%
P54042	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	34%	100%
Q0W1X2	Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)	34%	100%
Q10232	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	51%	100%
Q12ZT5	Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)	33%	100%
Q18GG5	Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)	34%	100%
Q1QN15	Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14)	25%	100%
Q211G3	Rhodopseudomonas palustris (strain BisB18)	28%	100%
Q22AX5	Tetrahymena thermophila (strain SB210)	44%	100%
Q2FSG5	Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)	34%	100%
Q2NFX3	Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)	36%	100%
Q3IMX2	Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB 2260 / Gabara)	33%	100%
Q3SSV1	Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255)	26%	100%
Q3SYR7	Bos taurus	48%	99%
Q46GB1	Methanosarcina barkeri (strain Fusaro / DSM 804)	34%	100%
Q4Q6V5	Leishmania major	99%	100%
Q54XI5	Dictyostelium discoideum	50%	100%
Q5AEN2	Candida albicans (strain SC5314 / ATCC MYA-2876)	52%	99%
Q5IFJ7	Macaca fascicularis	48%	99%
Q5JJG4	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	37%	100%
Q5R9Q7	Pongo abelii	48%	99%
Q6L1B1	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	27%	100%
Q6LXD7	Methanococcus maripaludis (strain S2 / LL)	36%	100%
Q74MR6	Nanoarchaeum equitans (strain Kin4-M)	30%	99%
Q8PV34	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	34%	100%
Q8TRT1	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	35%	100%
Q8TW14	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	32%	93%
Q8U015	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	37%	100%
Q8ZVA7	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	33%	97%
Q90YW0	Ictalurus punctatus	47%	99%
Q95Y90	Caenorhabditis elegans	51%	100%
Q963B7	Spodoptera frugiperda	51%	100%
Q975J6	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	35%	100%
Q97BW0	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	26%	100%
Q9HIS3	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	27%	100%
Q9HPB8	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	32%	100%
Q9SZX9	Arabidopsis thaliana	48%	98%
Q9UX91	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	34%	100%
Q9V1V1	Pyrococcus abyssi (strain GE5 / Orsay)	38%	100%
Q9YF91	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	37%	100%