IQ_calmodulin-binding_motif_containing_protein_-_putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QC85_LEIMA

TriTrypDb:

LmjF.21.1110 , LMJLV39_210019200 , LMJSD75_210019300

Length:

1761

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QC85

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	2
GO:0005515	protein binding	2	2
GO:0005516	calmodulin binding	3	2

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	183	187	PF00656	0.730
CLV_C14_Caspase3-7	400	404	PF00656	0.427
CLV_C14_Caspase3-7	424	428	PF00656	0.473
CLV_MEL_PAP_1	1177	1183	PF00089	0.402
CLV_NRD_NRD_1	106	108	PF00675	0.547
CLV_NRD_NRD_1	1061	1063	PF00675	0.400
CLV_NRD_NRD_1	1089	1091	PF00675	0.395
CLV_NRD_NRD_1	1165	1167	PF00675	0.413
CLV_NRD_NRD_1	1188	1190	PF00675	0.339
CLV_NRD_NRD_1	1195	1197	PF00675	0.346

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIB0	Leptomonas seymouri	53%	97%
A0A1X0NY24	Trypanosomatidae	38%	100%
A0A3Q8IDZ3	Leishmania donovani	91%	100%
A0A3R7KW01	Trypanosoma rangeli	36%	100%
A4HBW9	Leishmania braziliensis	74%	100%
D0A184	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
E9AGX9	Leishmania infantum	91%	100%
E9AV95	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	99%
V5BE65	Trypanosoma cruzi	35%	100%

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