Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QC82_LEIMA

TriTrypDb:

LmjF.21.1140 , LMJLV39_210019500 , LMJSD75_210019600

Length:

303

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QC82

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QC82

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	255	259	PF00656	0.650
CLV_NRD_NRD_1	245	247	PF00675	0.721
CLV_NRD_NRD_1	284	286	PF00675	0.532
CLV_PCSK_KEX2_1	187	189	PF00082	0.512
CLV_PCSK_KEX2_1	245	247	PF00082	0.790
CLV_PCSK_KEX2_1	249	251	PF00082	0.765
CLV_PCSK_PC1ET2_1	187	189	PF00082	0.512
CLV_PCSK_PC1ET2_1	249	251	PF00082	0.691
CLV_PCSK_PC7_1	245	251	PF00082	0.610
DEG_Nend_UBRbox_1	1	4	PF02207	0.650
DOC_CYCLIN_yCln2_LP_2	24	30	PF00134	0.477
DOC_MAPK_HePTP_8	18	30	PF00069	0.504
DOC_MAPK_MEF2A_6	21	30	PF00069	0.492
DOC_MAPK_MEF2A_6	47	54	PF00069	0.517
DOC_PP2B_LxvP_1	24	27	PF13499	0.484
DOC_USP7_MATH_1	99	103	PF00917	0.769
DOC_WW_Pin1_4	167	172	PF00397	0.745
DOC_WW_Pin1_4	216	221	PF00397	0.640
DOC_WW_Pin1_4	298	303	PF00397	0.513
LIG_14-3-3_CanoR_1	222	231	PF00244	0.690
LIG_14-3-3_CanoR_1	285	291	PF00244	0.469
LIG_14-3-3_CanoR_1	51	61	PF00244	0.447
LIG_14-3-3_CanoR_1	9	18	PF00244	0.656
LIG_CtBP_PxDLS_1	27	31	PF00389	0.569
LIG_FHA_1	11	17	PF00498	0.712
LIG_FHA_1	226	232	PF00498	0.677
LIG_FHA_1	237	243	PF00498	0.572
LIG_LIR_Nem_3	297	303	PF02991	0.696
LIG_NRBOX	146	152	PF00104	0.571
LIG_PDZ_Class_1	298	303	PF00595	0.513
LIG_SH2_STAT5	116	119	PF00017	0.597
LIG_TRAF2_1	287	290	PF00917	0.583
LIG_TYR_ITIM	298	303	PF00017	0.603
MOD_CDC14_SPxK_1	219	222	PF00782	0.655
MOD_CDK_SPxK_1	216	222	PF00069	0.643
MOD_CK1_1	102	108	PF00069	0.684
MOD_CK1_1	225	231	PF00069	0.653
MOD_CK2_1	125	131	PF00069	0.406
MOD_CK2_1	284	290	PF00069	0.687
MOD_Cter_Amidation	247	250	PF01082	0.616
MOD_GlcNHglycan	159	162	PF01048	0.635
MOD_GlcNHglycan	204	207	PF01048	0.554
MOD_GlcNHglycan	70	73	PF01048	0.736
MOD_GSK3_1	125	132	PF00069	0.498
MOD_GSK3_1	150	157	PF00069	0.543
MOD_GSK3_1	163	170	PF00069	0.641
MOD_N-GLC_1	28	33	PF02516	0.510
MOD_N-GLC_2	110	112	PF02516	0.601
MOD_NEK2_1	108	113	PF00069	0.495
MOD_NEK2_1	28	33	PF00069	0.510
MOD_NEK2_1	68	73	PF00069	0.629
MOD_PIKK_1	170	176	PF00454	0.733
MOD_PIKK_1	87	93	PF00454	0.543
MOD_PKA_1	249	255	PF00069	0.638
MOD_PKA_2	249	255	PF00069	0.638
MOD_PKA_2	284	290	PF00069	0.646
MOD_PKA_2	87	93	PF00069	0.541
MOD_Plk_1	117	123	PF00069	0.486
MOD_Plk_1	163	169	PF00069	0.531
MOD_Plk_1	236	242	PF00069	0.732
MOD_Plk_1	28	34	PF00069	0.514
MOD_Plk_2-3	284	290	PF00069	0.602
MOD_Plk_4	28	34	PF00069	0.514
MOD_ProDKin_1	167	173	PF00069	0.743
MOD_ProDKin_1	216	222	PF00069	0.643
MOD_SUMO_rev_2	283	287	PF00179	0.494
TRG_ENDOCYTIC_2	137	140	PF00928	0.482
TRG_ENDOCYTIC_2	295	298	PF00928	0.544
TRG_ENDOCYTIC_2	300	303	PF00928	0.532
TRG_ER_diArg_1	245	247	PF00400	0.722
TRG_ER_diArg_1	291	294	PF00400	0.695
TRG_Pf-PMV_PEXEL_1	193	198	PF00026	0.530

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3P3	Leptomonas seymouri	35%	96%
A0A3Q8IL55	Leishmania donovani	91%	100%
A4HC50	Leishmania braziliensis	67%	93%
A4HZ90	Leishmania infantum	91%	100%
E9AV98	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	97%