Ribosomal protein L1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Ribosomal protein L1p/L10e family, putative

Species:

Leishmania major

UniProt:

Q4QC78_LEIMA

TriTrypDb:

LmjF.21.1180 , LMJLV39_210019900 , LMJSD75_210020100

Length:

267

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	2
GO:0043226	organelle	2	3
GO:0043228	non-membrane-bounded organelle	3	3
GO:0043229	intracellular organelle	3	3
GO:0043232	intracellular non-membrane-bounded organelle	4	3
GO:0110165	cellular anatomical entity	1	3
GO:0005840	ribosome	5	1

Expansion

Sequence features

Q4QC78

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QC78

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	145	149	PF00656	0.270
CLV_MEL_PAP_1	209	215	PF00089	0.321
CLV_NRD_NRD_1	123	125	PF00675	0.245
CLV_NRD_NRD_1	172	174	PF00675	0.379
CLV_PCSK_FUR_1	121	125	PF00082	0.229
CLV_PCSK_KEX2_1	120	122	PF00082	0.317
CLV_PCSK_KEX2_1	123	125	PF00082	0.322
CLV_PCSK_KEX2_1	5	7	PF00082	0.481
CLV_PCSK_KEX2_1	96	98	PF00082	0.314
CLV_PCSK_PC1ET2_1	120	122	PF00082	0.307
CLV_PCSK_PC1ET2_1	5	7	PF00082	0.481
CLV_PCSK_PC1ET2_1	96	98	PF00082	0.314
CLV_PCSK_SKI1_1	11	15	PF00082	0.533
CLV_PCSK_SKI1_1	124	128	PF00082	0.351
CLV_PCSK_SKI1_1	174	178	PF00082	0.304
DOC_CKS1_1	175	180	PF01111	0.420
DOC_MAPK_gen_1	254	263	PF00069	0.570
DOC_MAPK_MEF2A_6	257	265	PF00069	0.591
DOC_PP1_RVXF_1	255	261	PF00149	0.562
DOC_PP2B_LxvP_1	81	84	PF13499	0.302
DOC_PP4_FxxP_1	46	49	PF00568	0.368
DOC_PP4_FxxP_1	65	68	PF00568	0.321
DOC_USP7_MATH_1	163	167	PF00917	0.394
DOC_WW_Pin1_4	174	179	PF00397	0.346
LIG_14-3-3_CanoR_1	123	133	PF00244	0.388
LIG_14-3-3_CanoR_1	77	84	PF00244	0.321
LIG_FHA_1	145	151	PF00498	0.462
LIG_FHA_1	195	201	PF00498	0.352
LIG_FHA_1	253	259	PF00498	0.454
LIG_FHA_1	76	82	PF00498	0.321
LIG_FHA_1	8	14	PF00498	0.474
LIG_FHA_2	143	149	PF00498	0.471
LIG_FHA_2	175	181	PF00498	0.386
LIG_Integrin_isoDGR_2	75	77	PF01839	0.321
LIG_KLC1_Yacidic_2	40	45	PF13176	0.475
LIG_LIR_Apic_2	45	49	PF02991	0.364
LIG_LIR_Apic_2	62	68	PF02991	0.314
LIG_LIR_Gen_1	127	136	PF02991	0.303
LIG_LIR_Gen_1	40	51	PF02991	0.386
LIG_LIR_Nem_3	127	132	PF02991	0.303
LIG_LIR_Nem_3	237	241	PF02991	0.307
LIG_LIR_Nem_3	40	46	PF02991	0.367
LIG_Pex14_2	238	242	PF04695	0.307
LIG_SH2_CRK	101	105	PF00017	0.321
LIG_SH2_STAP1	101	105	PF00017	0.321
LIG_SH2_STAT3	15	18	PF00017	0.562
LIG_SH2_STAT5	244	247	PF00017	0.340
LIG_SH2_STAT5	43	46	PF00017	0.463
LIG_SH3_3	166	172	PF00018	0.372
LIG_SUMO_SIM_anti_2	247	252	PF11976	0.229
LIG_TRAF2_1	37	40	PF00917	0.551
MOD_CK1_1	153	159	PF00069	0.386
MOD_CK1_1	249	255	PF00069	0.316
MOD_CK1_1	29	35	PF00069	0.715
MOD_CK1_1	50	56	PF00069	0.514
MOD_GlcNHglycan	156	159	PF01048	0.415
MOD_GlcNHglycan	166	169	PF01048	0.413
MOD_GSK3_1	150	157	PF00069	0.366
MOD_GSK3_1	190	197	PF00069	0.355
MOD_GSK3_1	26	33	PF00069	0.672
MOD_N-GLC_1	252	257	PF02516	0.427
MOD_NEK2_1	190	195	PF00069	0.351
MOD_NEK2_1	7	12	PF00069	0.467
MOD_PIKK_1	190	196	PF00454	0.346
MOD_PKA_2	184	190	PF00069	0.321
MOD_PKA_2	76	82	PF00069	0.328
MOD_Plk_1	246	252	PF00069	0.420
MOD_Plk_4	237	243	PF00069	0.330
MOD_Plk_4	246	252	PF00069	0.344
MOD_Plk_4	47	53	PF00069	0.440
MOD_ProDKin_1	174	180	PF00069	0.346
MOD_SUMO_for_1	234	237	PF00179	0.346
TRG_DiLeu_BaEn_2	255	261	PF01217	0.456
TRG_DiLeu_BaEn_4	183	189	PF01217	0.335
TRG_DiLeu_BaEn_4	39	45	PF01217	0.414
TRG_DiLeu_BaLyEn_6	3	8	PF01217	0.501
TRG_ENDOCYTIC_2	101	104	PF00928	0.321
TRG_ENDOCYTIC_2	43	46	PF00928	0.463
TRG_ER_diArg_1	121	124	PF00400	0.345
TRG_ER_diArg_1	257	260	PF00400	0.545
TRG_NLS_MonoExtC_3	119	124	PF00514	0.229
TRG_Pf-PMV_PEXEL_1	243	247	PF00026	0.356

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HUF4	Leptomonas seymouri	73%	100%
A0A0S4JGP8	Bodo saltans	48%	100%
A0A1X0NYA3	Trypanosomatidae	53%	89%
A0A3Q8IC01	Leishmania donovani	93%	100%
A0A3R7N930	Trypanosoma rangeli	54%	92%
A4HBX4	Leishmania braziliensis	85%	100%
A4HZ94	Leishmania infantum	93%	100%
D0A178	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	90%
E9AVA2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%