MsrB domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QC68_LEIMA

TriTrypDb:

LmjF.21.1280 , LMJLV39_210020900 , LMJSD75_210021100

Length:

443

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QC68

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QC68

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	413	417	PF00656	0.659
DEG_APCC_DBOX_1	372	380	PF00400	0.545
DEG_Nend_UBRbox_2	1	3	PF02207	0.638
DEG_SCF_FBW7_1	432	437	PF00400	0.599
DEG_SPOP_SBC_1	10	14	PF00917	0.658
DEG_SPOP_SBC_1	434	438	PF00917	0.603
DOC_CKS1_1	238	243	PF01111	0.498
DOC_CYCLIN_RxL_1	19	30	PF00134	0.651
DOC_MAPK_gen_1	19	27	PF00069	0.751
DOC_MAPK_JIP1_4	21	27	PF00069	0.650

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1P9M4	Leptomonas seymouri	41%	68%
A0A3S7WWN0	Leishmania donovani	89%	100%
A4HZC5	Leishmania infantum	89%	100%
E9AVB2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	96%

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