Palmitoyltransferase. Leishmaniids have +2 extra TM segments at the N-terminus while all other Kinetoplastids typically only have the 4 core ones.. Localization: ER (by homology)
Source | Evidence on protein | Close homologs |
---|---|---|
Cuervo et al. | no | yes: 0 |
Hassani et al. | no | yes: 0 |
Forrest at al. (metacyclic) | no | yes: 0 |
Forrest at al. (procyclic) | no | yes: 0 |
Silverman et al. | no | yes: 0 |
Pissara et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Pires et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Silverman et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Jamdhade et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
DeepLoc | ||
SignalP6 | no | yes: 0, no: 6 |
NetGPI | no | yes: 0, no: 6 |
Term | Name | Level | Count |
---|---|---|---|
GO:0005783 | endoplasmic reticulum | 5 | 3 |
GO:0005794 | Golgi apparatus | 5 | 3 |
GO:0016020 | membrane | 2 | 7 |
GO:0043226 | organelle | 2 | 3 |
GO:0043227 | membrane-bounded organelle | 3 | 3 |
GO:0043229 | intracellular organelle | 3 | 3 |
GO:0043231 | intracellular membrane-bounded organelle | 4 | 3 |
GO:0110165 | cellular anatomical entity | 1 | 7 |
GO:0005789 | endoplasmic reticulum membrane | 4 | 1 |
GO:0031090 | organelle membrane | 3 | 1 |
Related structures:
AlphaFold database: Q4QC55
Term | Name | Level | Count |
---|---|---|---|
GO:0006497 | protein lipidation | 5 | 3 |
GO:0006605 | protein targeting | 5 | 3 |
GO:0006612 | protein targeting to membrane | 5 | 3 |
GO:0006807 | nitrogen compound metabolic process | 2 | 3 |
GO:0006810 | transport | 3 | 3 |
GO:0006886 | intracellular protein transport | 4 | 3 |
GO:0006897 | endocytosis | 5 | 3 |
GO:0008104 | protein localization | 4 | 3 |
GO:0008152 | metabolic process | 1 | 3 |
GO:0009987 | cellular process | 1 | 3 |
GO:0015031 | protein transport | 4 | 3 |
GO:0016192 | vesicle-mediated transport | 4 | 3 |
GO:0018193 | peptidyl-amino acid modification | 5 | 3 |
GO:0018198 | peptidyl-cysteine modification | 6 | 3 |
GO:0018230 | peptidyl-L-cysteine S-palmitoylation | 7 | 3 |
GO:0018231 | peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine | 7 | 3 |
GO:0018345 | protein palmitoylation | 6 | 3 |
GO:0019538 | protein metabolic process | 3 | 3 |
GO:0033036 | macromolecule localization | 2 | 3 |
GO:0036211 | protein modification process | 4 | 3 |
GO:0043170 | macromolecule metabolic process | 3 | 3 |
GO:0043412 | macromolecule modification | 4 | 3 |
GO:0043543 | protein acylation | 5 | 3 |
GO:0044238 | primary metabolic process | 2 | 3 |
GO:0045184 | establishment of protein localization | 3 | 3 |
GO:0046907 | intracellular transport | 3 | 3 |
GO:0051179 | localization | 1 | 3 |
GO:0051234 | establishment of localization | 2 | 3 |
GO:0051641 | cellular localization | 2 | 3 |
GO:0051649 | establishment of localization in cell | 3 | 3 |
GO:0051668 | localization within membrane | 3 | 3 |
GO:0070727 | cellular macromolecule localization | 3 | 3 |
GO:0071702 | organic substance transport | 4 | 3 |
GO:0071704 | organic substance metabolic process | 2 | 3 |
GO:0071705 | nitrogen compound transport | 4 | 3 |
GO:0072657 | protein localization to membrane | 4 | 3 |
GO:0090150 | establishment of protein localization to membrane | 4 | 3 |
GO:1901564 | organonitrogen compound metabolic process | 3 | 3 |
Term | Name | Level | Count |
---|---|---|---|
GO:0003824 | catalytic activity | 1 | 7 |
GO:0016409 | palmitoyltransferase activity | 5 | 7 |
GO:0016417 | S-acyltransferase activity | 5 | 7 |
GO:0016740 | transferase activity | 2 | 7 |
GO:0016746 | acyltransferase activity | 3 | 7 |
GO:0016747 | acyltransferase activity, transferring groups other than amino-acyl groups | 4 | 7 |
GO:0019706 | protein-cysteine S-palmitoyltransferase activity | 4 | 7 |
GO:0019707 | protein-cysteine S-acyltransferase activity | 3 | 7 |
GO:0140096 | catalytic activity, acting on a protein | 2 | 7 |
Leishmania | From | To | Domain/Motif | Score |
---|---|---|---|---|
CLV_C14_Caspase3-7 | 140 | 144 | PF00656 | 0.762 |
CLV_C14_Caspase3-7 | 187 | 191 | PF00656 | 0.748 |
CLV_C14_Caspase3-7 | 230 | 234 | PF00656 | 0.802 |
CLV_NRD_NRD_1 | 13 | 15 | PF00675 | 0.520 |
CLV_NRD_NRD_1 | 268 | 270 | PF00675 | 0.512 |
CLV_NRD_NRD_1 | 324 | 326 | PF00675 | 0.438 |
CLV_NRD_NRD_1 | 331 | 333 | PF00675 | 0.355 |
CLV_NRD_NRD_1 | 399 | 401 | PF00675 | 0.635 |
CLV_NRD_NRD_1 | 403 | 405 | PF00675 | 0.594 |
CLV_NRD_NRD_1 | 529 | 531 | PF00675 | 0.567 |
CLV_NRD_NRD_1 | 552 | 554 | PF00675 | 0.469 |
CLV_PCSK_KEX2_1 | 13 | 15 | PF00082 | 0.519 |
CLV_PCSK_KEX2_1 | 268 | 270 | PF00082 | 0.512 |
CLV_PCSK_KEX2_1 | 324 | 326 | PF00082 | 0.438 |
CLV_PCSK_KEX2_1 | 331 | 333 | PF00082 | 0.355 |
CLV_PCSK_KEX2_1 | 403 | 405 | PF00082 | 0.622 |
CLV_PCSK_KEX2_1 | 463 | 465 | PF00082 | 0.399 |
CLV_PCSK_KEX2_1 | 481 | 483 | PF00082 | 0.363 |
CLV_PCSK_KEX2_1 | 529 | 531 | PF00082 | 0.526 |
CLV_PCSK_KEX2_1 | 552 | 554 | PF00082 | 0.469 |
CLV_PCSK_PC1ET2_1 | 463 | 465 | PF00082 | 0.380 |
CLV_PCSK_PC1ET2_1 | 481 | 483 | PF00082 | 0.382 |
CLV_PCSK_SKI1_1 | 257 | 261 | PF00082 | 0.551 |
CLV_PCSK_SKI1_1 | 331 | 335 | PF00082 | 0.438 |
CLV_PCSK_SKI1_1 | 464 | 468 | PF00082 | 0.438 |
CLV_PCSK_SKI1_1 | 518 | 522 | PF00082 | 0.513 |
CLV_PCSK_SKI1_1 | 529 | 533 | PF00082 | 0.469 |
CLV_PCSK_SKI1_1 | 8 | 12 | PF00082 | 0.517 |
DEG_APCC_DBOX_1 | 13 | 21 | PF00400 | 0.725 |
DEG_APCC_DBOX_1 | 256 | 264 | PF00400 | 0.688 |
DEG_APCC_DBOX_1 | 512 | 520 | PF00400 | 0.694 |
DEG_Nend_UBRbox_2 | 1 | 3 | PF02207 | 0.752 |
DOC_CKS1_1 | 67 | 72 | PF01111 | 0.517 |
DOC_CYCLIN_RxL_1 | 460 | 471 | PF00134 | 0.473 |
DOC_CYCLIN_RxL_1 | 498 | 507 | PF00134 | 0.695 |
DOC_CYCLIN_yCln2_LP_2 | 425 | 431 | PF00134 | 0.438 |
DOC_MAPK_gen_1 | 13 | 20 | PF00069 | 0.661 |
DOC_MAPK_gen_1 | 313 | 322 | PF00069 | 0.745 |
DOC_MAPK_gen_1 | 552 | 560 | PF00069 | 0.662 |
DOC_MAPK_MEF2A_6 | 13 | 22 | PF00069 | 0.657 |
DOC_MAPK_MEF2A_6 | 309 | 316 | PF00069 | 0.756 |
DOC_MAPK_MEF2A_6 | 553 | 562 | PF00069 | 0.694 |
DOC_PP1_RVXF_1 | 36 | 43 | PF00149 | 0.572 |
DOC_PP1_RVXF_1 | 499 | 506 | PF00149 | 0.695 |
DOC_PP2B_LxvP_1 | 320 | 323 | PF13499 | 0.784 |
DOC_PP2B_LxvP_1 | 333 | 336 | PF13499 | 0.483 |
DOC_PP2B_LxvP_1 | 425 | 428 | PF13499 | 0.438 |
DOC_PP2B_PxIxI_1 | 217 | 223 | PF00149 | 0.744 |
DOC_PP4_FxxP_1 | 169 | 172 | PF00568 | 0.836 |
DOC_USP7_MATH_1 | 472 | 476 | PF00917 | 0.595 |
DOC_USP7_UBL2_3 | 518 | 522 | PF12436 | 0.672 |
DOC_WW_Pin1_4 | 142 | 147 | PF00397 | 0.818 |
DOC_WW_Pin1_4 | 168 | 173 | PF00397 | 0.740 |
DOC_WW_Pin1_4 | 190 | 195 | PF00397 | 0.852 |
DOC_WW_Pin1_4 | 409 | 414 | PF00397 | 0.370 |
DOC_WW_Pin1_4 | 492 | 497 | PF00397 | 0.628 |
DOC_WW_Pin1_4 | 66 | 71 | PF00397 | 0.522 |
LIG_14-3-3_CanoR_1 | 268 | 274 | PF00244 | 0.761 |
LIG_14-3-3_CanoR_1 | 287 | 292 | PF00244 | 0.673 |
LIG_14-3-3_CanoR_1 | 529 | 536 | PF00244 | 0.768 |
LIG_AP2alpha_1 | 505 | 509 | PF02296 | 0.680 |
LIG_BRCT_BRCA1_1 | 270 | 274 | PF00533 | 0.774 |
LIG_BRCT_BRCA1_1 | 487 | 491 | PF00533 | 0.759 |
LIG_CaM_NSCaTE_8 | 378 | 385 | PF13499 | 0.473 |
LIG_Clathr_ClatBox_1 | 297 | 301 | PF01394 | 0.795 |
LIG_deltaCOP1_diTrp_1 | 541 | 547 | PF00928 | 0.696 |
LIG_EH1_1 | 444 | 452 | PF00400 | 0.443 |
LIG_eIF4E_1 | 460 | 466 | PF01652 | 0.534 |
LIG_eIF4E_1 | 580 | 586 | PF01652 | 0.725 |
LIG_FHA_1 | 200 | 206 | PF00498 | 0.791 |
LIG_FHA_1 | 237 | 243 | PF00498 | 0.861 |
LIG_FHA_1 | 254 | 260 | PF00498 | 0.596 |
LIG_FHA_1 | 268 | 274 | PF00498 | 0.611 |
LIG_FHA_1 | 35 | 41 | PF00498 | 0.534 |
LIG_FHA_1 | 383 | 389 | PF00498 | 0.473 |
LIG_FHA_1 | 435 | 441 | PF00498 | 0.390 |
LIG_FHA_1 | 468 | 474 | PF00498 | 0.639 |
LIG_FHA_1 | 51 | 57 | PF00498 | 0.338 |
LIG_FHA_1 | 580 | 586 | PF00498 | 0.725 |
LIG_FHA_2 | 185 | 191 | PF00498 | 0.813 |
LIG_FHA_2 | 294 | 300 | PF00498 | 0.776 |
LIG_FHA_2 | 347 | 353 | PF00498 | 0.595 |
LIG_FHA_2 | 469 | 475 | PF00498 | 0.639 |
LIG_FHA_2 | 509 | 515 | PF00498 | 0.685 |
LIG_Integrin_RGD_1 | 227 | 229 | PF01839 | 0.605 |
LIG_LIR_Apic_2 | 109 | 115 | PF02991 | 0.815 |
LIG_LIR_Apic_2 | 168 | 172 | PF02991 | 0.725 |
LIG_LIR_Gen_1 | 456 | 466 | PF02991 | 0.534 |
LIG_LIR_Gen_1 | 53 | 60 | PF02991 | 0.534 |
LIG_LIR_Gen_1 | 582 | 591 | PF02991 | 0.742 |
LIG_LIR_Gen_1 | 72 | 83 | PF02991 | 0.199 |
LIG_LIR_Nem_3 | 214 | 220 | PF02991 | 0.851 |
LIG_LIR_Nem_3 | 385 | 390 | PF02991 | 0.534 |
LIG_LIR_Nem_3 | 456 | 461 | PF02991 | 0.534 |
LIG_LIR_Nem_3 | 53 | 57 | PF02991 | 0.385 |
LIG_LIR_Nem_3 | 565 | 570 | PF02991 | 0.705 |
LIG_LIR_Nem_3 | 582 | 586 | PF02991 | 0.572 |
LIG_LIR_Nem_3 | 72 | 78 | PF02991 | 0.199 |
LIG_LIR_Nem_3 | 86 | 90 | PF02991 | 0.534 |
LIG_LYPXL_SIV_4 | 428 | 436 | PF13949 | 0.438 |
LIG_NRBOX | 293 | 299 | PF00104 | 0.800 |
LIG_NRBOX | 77 | 83 | PF00104 | 0.473 |
LIG_Pex14_1 | 563 | 567 | PF04695 | 0.689 |
LIG_Pex14_2 | 29 | 33 | PF04695 | 0.758 |
LIG_Pex14_2 | 505 | 509 | PF04695 | 0.680 |
LIG_SH2_CRK | 112 | 116 | PF00017 | 0.779 |
LIG_SH2_CRK | 390 | 394 | PF00017 | 0.534 |
LIG_SH2_CRK | 493 | 497 | PF00017 | 0.718 |
LIG_SH2_GRB2like | 460 | 463 | PF00017 | 0.534 |
LIG_SH2_GRB2like | 90 | 93 | PF00017 | 0.534 |
LIG_SH2_PTP2 | 75 | 78 | PF00017 | 0.473 |
LIG_SH2_SRC | 125 | 128 | PF00017 | 0.773 |
LIG_SH2_STAP1 | 116 | 120 | PF00017 | 0.717 |
LIG_SH2_STAT3 | 9 | 12 | PF00017 | 0.667 |
LIG_SH2_STAT5 | 110 | 113 | PF00017 | 0.773 |
LIG_SH2_STAT5 | 116 | 119 | PF00017 | 0.697 |
LIG_SH2_STAT5 | 16 | 19 | PF00017 | 0.700 |
LIG_SH2_STAT5 | 326 | 329 | PF00017 | 0.548 |
LIG_SH2_STAT5 | 369 | 372 | PF00017 | 0.534 |
LIG_SH2_STAT5 | 392 | 395 | PF00017 | 0.438 |
LIG_SH2_STAT5 | 439 | 442 | PF00017 | 0.473 |
LIG_SH2_STAT5 | 460 | 463 | PF00017 | 0.534 |
LIG_SH2_STAT5 | 477 | 480 | PF00017 | 0.524 |
LIG_SH2_STAT5 | 75 | 78 | PF00017 | 0.372 |
LIG_SH2_STAT5 | 90 | 93 | PF00017 | 0.534 |
LIG_SH3_3 | 177 | 183 | PF00018 | 0.829 |
LIG_SH3_3 | 191 | 197 | PF00018 | 0.716 |
LIG_SH3_3 | 204 | 210 | PF00018 | 0.707 |
LIG_SH3_3 | 282 | 288 | PF00018 | 0.784 |
LIG_SH3_3 | 425 | 431 | PF00018 | 0.438 |
LIG_SH3_3 | 575 | 581 | PF00018 | 0.766 |
LIG_SUMO_SIM_par_1 | 295 | 301 | PF11976 | 0.793 |
LIG_TRAF2_1 | 138 | 141 | PF00917 | 0.734 |
LIG_TYR_ITIM | 388 | 393 | PF00017 | 0.473 |
LIG_TYR_ITIM | 73 | 78 | PF00017 | 0.534 |
LIG_WRC_WIRS_1 | 30 | 35 | PF05994 | 0.710 |
LIG_WRC_WIRS_1 | 51 | 56 | PF05994 | 0.534 |
LIG_WRC_WIRS_1 | 567 | 572 | PF05994 | 0.664 |
LIG_WRC_WIRS_1 | 580 | 585 | PF05994 | 0.494 |
LIG_WRC_WIRS_1 | 84 | 89 | PF05994 | 0.534 |
LIG_WW_1 | 107 | 110 | PF00397 | 0.718 |
LIG_WW_2 | 210 | 213 | PF00397 | 0.817 |
LIG_WW_3 | 310 | 314 | PF00397 | 0.699 |
MOD_CDC14_SPxK_1 | 171 | 174 | PF00782 | 0.815 |
MOD_CDC14_SPxK_1 | 412 | 415 | PF00782 | 0.534 |
MOD_CDK_SPxK_1 | 168 | 174 | PF00069 | 0.812 |
MOD_CDK_SPxK_1 | 409 | 415 | PF00069 | 0.534 |
MOD_CK1_1 | 128 | 134 | PF00069 | 0.838 |
MOD_CK1_1 | 135 | 141 | PF00069 | 0.736 |
MOD_CK1_1 | 255 | 261 | PF00069 | 0.684 |
MOD_CK1_1 | 438 | 444 | PF00069 | 0.443 |
MOD_CK2_1 | 135 | 141 | PF00069 | 0.670 |
MOD_CK2_1 | 293 | 299 | PF00069 | 0.705 |
MOD_CK2_1 | 468 | 474 | PF00069 | 0.534 |
MOD_CMANNOS | 375 | 378 | PF00535 | 0.534 |
MOD_GlcNHglycan | 229 | 233 | PF01048 | 0.797 |
MOD_GlcNHglycan | 270 | 273 | PF01048 | 0.706 |
MOD_GlcNHglycan | 587 | 590 | PF01048 | 0.759 |
MOD_GSK3_1 | 114 | 121 | PF00069 | 0.670 |
MOD_GSK3_1 | 128 | 135 | PF00069 | 0.723 |
MOD_GSK3_1 | 149 | 156 | PF00069 | 0.739 |
MOD_GSK3_1 | 184 | 191 | PF00069 | 0.798 |
MOD_GSK3_1 | 264 | 271 | PF00069 | 0.606 |
MOD_GSK3_1 | 29 | 36 | PF00069 | 0.565 |
MOD_GSK3_1 | 378 | 385 | PF00069 | 0.534 |
MOD_GSK3_1 | 434 | 441 | PF00069 | 0.482 |
MOD_GSK3_1 | 468 | 475 | PF00069 | 0.482 |
MOD_GSK3_1 | 562 | 569 | PF00069 | 0.616 |
MOD_GSK3_1 | 65 | 72 | PF00069 | 0.585 |
MOD_GSK3_1 | 93 | 100 | PF00069 | 0.427 |
MOD_N-GLC_1 | 118 | 123 | PF02516 | 0.638 |
MOD_N-GLC_1 | 188 | 193 | PF02516 | 0.750 |
MOD_N-GLC_1 | 33 | 38 | PF02516 | 0.636 |
MOD_N-GLC_1 | 468 | 473 | PF02516 | 0.534 |
MOD_N-GLC_2 | 345 | 347 | PF02516 | 0.460 |
MOD_N-GLC_2 | 359 | 361 | PF02516 | 0.375 |
MOD_NEK2_1 | 184 | 189 | PF00069 | 0.806 |
MOD_NEK2_1 | 29 | 34 | PF00069 | 0.528 |
MOD_NEK2_1 | 382 | 387 | PF00069 | 0.534 |
MOD_NEK2_1 | 435 | 440 | PF00069 | 0.534 |
MOD_NEK2_1 | 453 | 458 | PF00069 | 0.233 |
MOD_NEK2_1 | 467 | 472 | PF00069 | 0.300 |
MOD_NEK2_1 | 508 | 513 | PF00069 | 0.587 |
MOD_NEK2_1 | 94 | 99 | PF00069 | 0.451 |
MOD_NEK2_2 | 472 | 477 | PF00069 | 0.473 |
MOD_PIKK_1 | 128 | 134 | PF00454 | 0.656 |
MOD_PIKK_1 | 149 | 155 | PF00454 | 0.761 |
MOD_PIKK_1 | 205 | 211 | PF00454 | 0.762 |
MOD_PKA_1 | 268 | 274 | PF00069 | 0.626 |
MOD_PKA_1 | 529 | 535 | PF00069 | 0.705 |
MOD_PKA_2 | 252 | 258 | PF00069 | 0.670 |
MOD_PKA_2 | 264 | 270 | PF00069 | 0.522 |
MOD_PKA_2 | 393 | 399 | PF00069 | 0.443 |
MOD_PKA_2 | 529 | 535 | PF00069 | 0.657 |
MOD_Plk_1 | 108 | 114 | PF00069 | 0.692 |
MOD_Plk_1 | 135 | 141 | PF00069 | 0.686 |
MOD_Plk_1 | 153 | 159 | PF00069 | 0.656 |
MOD_Plk_1 | 184 | 190 | PF00069 | 0.843 |
MOD_Plk_1 | 468 | 474 | PF00069 | 0.534 |
MOD_Plk_4 | 293 | 299 | PF00069 | 0.729 |
MOD_Plk_4 | 378 | 384 | PF00069 | 0.534 |
MOD_Plk_4 | 435 | 441 | PF00069 | 0.504 |
MOD_Plk_4 | 453 | 459 | PF00069 | 0.263 |
MOD_Plk_4 | 472 | 478 | PF00069 | 0.216 |
MOD_ProDKin_1 | 142 | 148 | PF00069 | 0.786 |
MOD_ProDKin_1 | 168 | 174 | PF00069 | 0.678 |
MOD_ProDKin_1 | 190 | 196 | PF00069 | 0.832 |
MOD_ProDKin_1 | 409 | 415 | PF00069 | 0.437 |
MOD_ProDKin_1 | 492 | 498 | PF00069 | 0.514 |
MOD_ProDKin_1 | 66 | 72 | PF00069 | 0.645 |
MOD_SUMO_for_1 | 521 | 524 | PF00179 | 0.573 |
TRG_DiLeu_LyEn_5 | 590 | 595 | PF01217 | 0.717 |
TRG_ENDOCYTIC_2 | 369 | 372 | PF00928 | 0.534 |
TRG_ENDOCYTIC_2 | 390 | 393 | PF00928 | 0.534 |
TRG_ENDOCYTIC_2 | 580 | 583 | PF00928 | 0.707 |
TRG_ENDOCYTIC_2 | 75 | 78 | PF00928 | 0.534 |
TRG_ER_diArg_1 | 312 | 315 | PF00400 | 0.723 |
TRG_ER_diArg_1 | 323 | 325 | PF00400 | 0.384 |
TRG_ER_diArg_1 | 331 | 333 | PF00400 | 0.250 |
TRG_ER_diArg_1 | 402 | 404 | PF00400 | 0.516 |
TRG_ER_diArg_1 | 552 | 554 | PF00400 | 0.576 |
TRG_NES_CRM1_1 | 154 | 166 | PF08389 | 0.740 |
TRG_NLS_MonoExtC_3 | 399 | 404 | PF00514 | 0.382 |
TRG_Pf-PMV_PEXEL_1 | 101 | 105 | PF00026 | 0.628 |
TRG_Pf-PMV_PEXEL_1 | 257 | 261 | PF00026 | 0.571 |
TRG_Pf-PMV_PEXEL_1 | 403 | 408 | PF00026 | 0.534 |
TRG_Pf-PMV_PEXEL_1 | 552 | 556 | PF00026 | 0.636 |
Protein | Taxonomy | Sequence identity | Coverage |
---|---|---|---|
A0A3Q8IAF5 | Leishmania donovani | 92% | 84% |
A4HC51 | Leishmania braziliensis | 67% | 100% |
A4HZD7 | Leishmania infantum | 92% | 100% |
E9AVC4 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 87% | 100% |
Q4QC56 | Leishmania major | 100% | 100% |